William Herman Prusoff

1953-2011 Pharmacology Yale University, New Haven, CT 
antiviral chemotherapy
"William Herman Prusoff"

(1920 - 2011)

Mean distance: 10.73


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Charles Glen King grad student 1950 Columbia
 (Relationship of pteroylglutamic acid to nucleic acid synthesis)
Arnold D. Welch post-doc 1949-1953 Western Reserve University
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Kim BJ, Zhang J, Tan S, et al. (2012) Synthesis and properties of 1-(3′-dihydroxyboryl-2′,3′- dideoxyribosyl)pyrimidines Organic and Biomolecular Chemistry. 10: 9349-9358
Martin JC, Hitchcock MJ, De Clercq E, et al. (2010) Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: a brief history of stavudine (D4T) and its comparison with other dideoxynucleosides. Antiviral Research. 85: 34-8
Pivazyan AD, Matteson DS, Fabry-Asztalos L, et al. (2000) Inhibition of HIV-1 protease by a boron-modified polypeptide Biochemical Pharmacology. 60: 927-936
Kukhanova M, Krayevsky A, Prusoff W, et al. (2000) Design of anti-HIV compounds: From nucleoside to nucleoside 5'- triphosphate analogs. Problems and perspectives Current Pharmaceutical Design. 6: 585-598
Kukhanova M, Li X, Chen SH, et al. (1998) Interaction of β-L-2',3'-dideoxy-2',3'-didehydro-5-fluoro-CTP with human immunodeficiency virus-1 reverse transcriptase and human DNA polymerases: Implications for human immunodeficiency virus drug design Molecular Pharmacology. 53: 801-807
Lin TS, Zhu JL, Dutschman GE, et al. (1993) Syntheses and biological evaluations of 3′-deoxy-3′-C-branched-chain-substituted nucleosides Journal of Medicinal Chemistry. 36: 353-362
Tai-Shun L, Schinazi RF, Zhu J, et al. (1993) Anti-HIV-1 activity and cellular pharmacology of various analogs of gossypol Biochemical Pharmacology. 46: 251-255
Prusoff W, Lin TS, Pivazyan A, et al. (1993) Empirical and rational approaches for development of inhibitors of the human immunodeficiency virus - HIV-1 Pharmacology and Therapeutics. 60: 315-329
August EM, He-Ying Q, Birks EM, et al. (1993) Metabolism and mode of selective inhibition of human immunodeficiency virus replication by 3'-azido-2',3'-dideoxy-5-iodouridine and 3'-azido-2',3'-dideoxy-5-bromouridine Biochemical Pharmacology. 45: 223-230
Pivazyan AD, Birks EM, Wood TG, et al. (1992) Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine Biochemical Pharmacology. 44: 947-953
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