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William Herman Prusoff

Affiliations: 
1953-2011 Pharmacology Yale University, New Haven, CT 
Area:
antiviral chemotherapy
Website:
http://news.yale.edu/2011/04/08/memoriam-william-h-prusoff
Google:
"William Herman Prusoff"
Bio:

(1920 - 2011)
http://yalemedicine.yale.edu/autumn1999/features/feature/55286/

Mean distance: 10.73
 

Parents

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Charles Glen King grad student 1950 Columbia
 (Relationship of pteroylglutamic acid to nucleic acid synthesis)
Arnold D. Welch post-doc 1949-1953 Western Reserve University
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Publications

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Kim BJ, Zhang J, Tan S, et al. (2012) Synthesis and properties of 1-(3′-dihydroxyboryl-2′,3′- dideoxyribosyl)pyrimidines Organic and Biomolecular Chemistry. 10: 9349-9358
Kukhanova M, Krayevsky A, Prusoff W, et al. (2000) Design of anti-HIV compounds: From nucleoside to nucleoside 5'- triphosphate analogs. Problems and perspectives Current Pharmaceutical Design. 6: 585-598
Lin TS, Zhu JL, Dutschman GE, et al. (1993) Syntheses and biological evaluations of 3′-deoxy-3′-C-branched-chain-substituted nucleosides Journal of Medicinal Chemistry. 36: 353-362
Tai-Shun L, Schinazi RF, Zhu J, et al. (1993) Anti-HIV-1 activity and cellular pharmacology of various analogs of gossypol Biochemical Pharmacology. 46: 251-255
Prusoff W, Lin TS, Pivazyan A, et al. (1993) Empirical and rational approaches for development of inhibitors of the human immunodeficiency virus - HIV-1 Pharmacology and Therapeutics. 60: 315-329
August EM, He-Ying Q, Birks EM, et al. (1993) Metabolism and mode of selective inhibition of human immunodeficiency virus replication by 3'-azido-2',3'-dideoxy-5-iodouridine and 3'-azido-2',3'-dideoxy-5-bromouridine Biochemical Pharmacology. 45: 223-230
Lin TS, Yang JH, Liu MC, et al. (1991) Synthesis and anticancer activity of various 3′-deoxy pyrimidine nucleoside analogues and crystal structure of 1-(3-deoxy-β-D-threo-pentofuranosyl)cytosine Journal of Medicinal Chemistry. 34: 693-701
Wood TG, Marongiu ME, Prusoff WH. (1991) Effect of ultraviolet light on DNA structure in 5-iodo-2′-deoxyuridine-substituted HSV-1 DNA Biochemical Pharmacology. 41: 439-444
Lin TS, Luo MZ, Liu MC, et al. (1991) Synthesis and anticancer and antiviral activities of various 2′- and 3′-methylidene-substituted nucleoside analogues and crystal structure of 2′-deoxy-2′-methylidenecytidine hydrochloride Journal of Medicinal Chemistry. 34: 2607-2615
Keilbaugh SA, Prusoff WH, Simpson MV. (1991) The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs Biochemical Pharmacology. 42: R5-R8
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