Nir London
Affiliations: | 2015- | Weizmann Institute of Science, Rehovot, Israel |
Area:
Chemical biology, drug discovery and designWebsite:
https://www.weizmann.ac.il/Organic_Chemistry/London/Google:
"Nir London"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Ora Schueler-Furman | grad student | 2007-2011 | Hebrew University (Computational Biology Tree) | |
| (Understanding, modeling and manipulating protein-peptide interactions.) | ||||
| Brian K. Shoichet | post-doc | 2012-2015 | UCSF | |
BETA: Related publications
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Publications
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| Algranati D, Oren R, Dassa B, et al. (2024) Dual targeting of histone deacetylases and MYC as potential treatment strategy for H3-K27M pediatric gliomas. Elife. 13 |
| McCorkindale W, Filep M, London N, et al. (2024) Deconvoluting low yield from weak potency in direct-to-biology workflows with machine learning. Rsc Medicinal Chemistry. 15: 1015-1021 |
| Gabizon R, Tivon B, Reddi RN, et al. (2023) A simple method for developing lysine targeted covalent protein reagents. Nature Communications. 14: 7933 |
| Boby ML, Fearon D, Ferla M, et al. (2023) Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science (New York, N.Y.). 382: eabo7201 |
| Saar KL, McCorkindale W, Fearon D, et al. (2023) Turning high-throughput structural biology into predictive inhibitor design. Proceedings of the National Academy of Sciences of the United States of America. 120: e2214168120 |
| Vanhoutte R, Barniol-Xicota M, Chiu W, et al. (2023) Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells. Chemical Science. 14: 1666-1672 |
| Reddi RN, Rogel A, Gabizon R, et al. (2023) Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry. Journal of the American Chemical Society |
| Bejan DS, Sundalam S, Jin H, et al. (2022) Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor. Chemical Science. 13: 13898-13906 |
| Hassan A, Pollak YE, Kilav-Levin R, et al. (2022) Kidney Failure Alters Parathyroid Pin1 Phosphorylation and Parathyroid Hormone mRNA-Binding Proteins Leading to Secondary Hyperparathyroidism. Journal of the American Society of Nephrology : Jasn |
| Gehrtz P, Marom S, Bührmann M, et al. (2022) Optimization of Covalent MKK7 Inhibitors Crude Nanomole-Scale Libraries. Journal of Medicinal Chemistry |