Michael D. Olp
Affiliations: | 2014-2019 | Biochemistry | Medical College of Wisconsin, Milwaukee, WI, United States |
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| Bursch KL, Goetz CJ, Jiao G, et al. (2024) Cancer-associated Polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression. The Journal of Biological Chemistry. 107146 |
| Bursch KL, Olp MD, Smith BC. (2023) Analysis of continuous enzyme kinetic data using ICEKAT. Methods in Enzymology. 690: 109-129 |
| Shishodia S, Nuñez R, Strohmier BP, et al. (2022) Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. Journal of Medicinal Chemistry |
| Kanack AJ, Olp MD, Newsom OJ, et al. (2022) Chemical regulation of the protein quality control E3 ubiquitin ligase C-terminus of Hsc70 interacting protein (CHIP). Chembiochem : a European Journal of Chemical Biology |
| Olp MD, Kalous KS, Smith BC. (2020) ICEKAT: an interactive online tool for calculating initial rates from continuous enzyme kinetic traces. Bmc Bioinformatics. 21: 186 |
| Olp MD, Sprague DJ, Goetz CJ, et al. (2020) Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites. Acs Chemical Biology |
| McCusker P, Mian MY, Li G, et al. (2019) Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni. Plos Neglected Tropical Diseases. 13: e0007826 |
| Egner JM, Jensen DR, Olp MD, et al. (2017) Development and Validation of 2D Difference Intensity Analysis for Chemical Library Screening by Protein-Detected NMR. Chembiochem : a European Journal of Chemical Biology |
| Olp M, Zhu N, Smith B. (2017) Metabolically-derived lysine acylations and neighboring modifications tune BET bromodomain binding to histone H4. Biochemistry |
| Kalous KS, Wynia-Smith SL, Olp MD, et al. (2016) Mechanism of Sirt1 NAD+-dependent Deacetylase Inhibition by Cysteine S-nitrosation. The Journal of Biological Chemistry |