Brian C Smith

Medical College of Wisconsin 
acetylation, bromodomains, sirtuins
"Brian Smith"
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Yang M, Li W, Harberg C, et al. (2020) Cysteine sulfenylation by CD36 signaling promotes arterial thrombosis in dyslipidemia. Blood Advances. 4: 4494-4507
Olp MD, Kalous KS, Smith BC. (2020) ICEKAT: an interactive online tool for calculating initial rates from continuous enzyme kinetic traces. Bmc Bioinformatics. 21: 186
Kalous KS, Wynia-Smith SL, Summers SB, et al. (2020) Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants. The Journal of Biological Chemistry
Olp MD, Sprague DJ, Goetz CJ, et al. (2020) Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites. Acs Chemical Biology
Hanson QM, Carley JR, Gilbreath TJ, et al. (2018) Calmodulin-induced conformational control and allostery underlying neuronal nitric oxide synthase activation. Journal of Molecular Biology
Kalous KS, Wynia-Smith SL, Olp MD, et al. (2016) Mechanism of Sirt1 NAD+-dependent Deacetylase Inhibition by Cysteine S-nitrosation. The Journal of Biological Chemistry
Wynia-Smith SL, Smith BC. (2016) Nitrosothiol formation and S-nitrosation signaling through nitric oxide synthases. Nitric Oxide : Biology and Chemistry
Zhou Y, Wynia-Smith SL, Couvertier SM, et al. (2016) Chemoproteomic Strategy to Quantitatively Monitor Transnitrosation Uncovers Functionally Relevant S-Nitrosation Sites on Cathepsin D and HADH2. Cell Chemical Biology
Rao M, Smith BC, Marletta MA. (2015) Nitric Oxide Mediates Biofilm Formation and Symbiosis in Silicibacter sp. Strain TrichCH4B. Mbio. 6: e00206-15
Shteyer E, Edvardson S, Wynia-Smith SL, et al. (2015) Truncating mutation in the nitric oxide synthase 1 gene is associated with infantile achalasia. Gastroenterology. 148: 533-536.e4
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