Brian C Smith, Ph.D.
Affiliations: | 2014- | Biochemistry | Medical College of Wisconsin |
Area:
acetylation, bromodomains, sirtuinsWebsite:
https://bsmith.scienceGoogle:
"Brian C. Smith"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Scott K. Silverman | research assistant | 2001-2003 | UIUC |
| John M. Denu | grad student | 2003-2009 | UW Madison |
| Michael A. Marletta | post-doc | 2009-2014 | University of California, Berkeley, Scripps Research Institute |
Children
Sign in to add trainee| Karina Bursch | grad student | Medical College of Wisconsin | |
| Raymundo Nuñez | grad student | 2020- | Medical College of Wisconsin |
| Paul Sidlowski | grad student | 2023- | Medical College of Wisconsin |
| Michael D. Olp | grad student | 2014-2019 | Medical College of Wisconsin |
| Kelsey S. Bohl | grad student | 2015-2020 | Medical College of Wisconsin |
| Christopher J. Goetz | grad student | 2016-2021 | Medical College of Wisconsin |
| Rachel Jones Lipinski | grad student | 2019-2023 | Medical College of Wisconsin |
| Joshua A. Nord | post-doc | 2019- | Medical College of Wisconsin |
| Moua Yang | post-doc | 2018-2019 | Medical College of Wisconsin |
| Daniel J. Sprague | post-doc | 2016-2021 | Medical College of Wisconsin |
| Shifali Shishodia | post-doc | 2019-2022 | Medical College of Wisconsin |
| Sarah L. Wynia Smith | research scientist | 2014- | Medical College of Wisconsin (Neurotree) |
BETA: Related publications
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Publications
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| Olp MD, Bursch KL, Wynia-Smith SL, et al. (2025) Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. The Journal of Biological Chemistry. 108289 |
| Nuñez R, Sidlowski PFW, Steen EA, et al. (2024) The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation. Acs Chemical Biology |
| Bohl K, Wynia-Smith SL, Jones Lipinski RA, et al. (2024) Inhibition of Sirtuin Deacylase Activity by Peroxynitrite. Biochemistry |
| Zhang J, Chang J, Chen V, et al. (2024) Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway. Biorxiv : the Preprint Server For Biology |
| Jones Lipinski RA, Stancill JS, Nuñez R, et al. (2024) Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology |
| Bursch KL, Goetz CJ, Smith BC. (2024) Current Trends in Sirtuin Activator and Inhibitor Development. Molecules (Basel, Switzerland). 29 |
| Bursch KL, Goetz CJ, Jiao G, et al. (2024) Cancer-associated Polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression. The Journal of Biological Chemistry. 107146 |
| Kerber PJ, Nuñez R, Jensen DR, et al. (2023) Fragment-based screening by protein-detected NMR spectroscopy. Methods in Enzymology. 690: 285-310 |
| Bursch KL, Olp MD, Smith BC. (2023) Analysis of continuous enzyme kinetic data using ICEKAT. Methods in Enzymology. 690: 109-129 |
| Ordonez-Rubiano SC, Maschinot CA, Wang S, et al. (2023) Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer. Journal of Medicinal Chemistry. 66: 11250-11270 |