Philipp Ottis
Affiliations: | Yale University, New Haven, CT |
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| Ottis P, Palladino C, Thienger P, et al. (2019) Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway. Acs Chemical Biology |
| Burslem GM, Ottis P, Jaime-Figueroa S, et al. (2018) Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure Degradation Relationships. Chemmedchem |
| Ottis P, Toure M, Cromm PM, et al. (2017) Assessing Different E3 Ligases for Small Molecule-induced Protein Ubiquitination and Degradation. Acs Chemical Biology |
| Ottis P, Crews CM. (2017) PROTACs: Induced Protein Degradation as a Therapeutic Strategy. Acs Chemical Biology |
| Korth C, Bader V, Trossbach S, et al. (2017) Functional Proteomics Backed by Genetics and Reverse Genetic Engineering: A Novel Successful Approach to Identify Schizophrenia Subsets European Neuropsychopharmacology. 27 |
| Schmitz M, Greis C, Ottis P, et al. (2014) Loss of prion protein leads to age-dependent behavioral abnormalities and changes in cytoskeletal protein expression. Molecular Neurobiology. 50: 923-36 |
| Ottis P, Topic B, Loos M, et al. (2013) Aging-induced proteostatic changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as a molecular circuitry for cognitive impairment. Plos One. 8: e75112 |
| Bader V, Ottis P, Pum M, et al. (2012) Generation, purification, and characterization of cell-invasive DISC1 protein species. Journal of Visualized Experiments : Jove. e4132 |
| Ottis P, Koppe K, Onisko B, et al. (2012) Human and rat brain lipofuscin proteome. Proteomics. 12: 2445-54 |