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Nathan David Thomsen

Affiliations: 
2010 Molecular  University of California, Berkeley, Berkeley, CA, United States 
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"Nathan Thomsen"
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James M. Berger grad student 2010 UC Berkeley
 (Structural Studies of Translocation Mechanism and Chemomechanical Coupling in Hexameric Helicases.)

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Thomsen ND, Lawson MR, Witkowsky LB, et al. (2016) Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor. Proceedings of the National Academy of Sciences of the United States of America
Seaman JE, Julien O, Lee PS, et al. (2016) Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues. Cell Death and Differentiation
Rettenmaier TJ, Sadowsky JD, Thomsen ND, et al. (2014) A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proceedings of the National Academy of Sciences of the United States of America. 111: 18590-5
Thomsen ND, Koerber JT, Wells JA. (2013) Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proceedings of the National Academy of Sciences of the United States of America. 110: 8477-82
Thomsen ND, Berger JM. (2012) Crystallization and X-ray structure determination of an RNA-dependent hexameric helicase. Methods in Enzymology. 511: 171-90
Berger JM, Thomsen ND. (2012) Unexpected Sophistication and Complexity of Chemomechanical Control Linkages in Nucleic Acid Motor Biophysical Journal. 102: 428a
Montpetit B, Thomsen ND, Helmke KJ, et al. (2011) A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export. Nature. 472: 238-42
Lombana TN, Echols N, Good MC, et al. (2010) Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure (London, England : 1993). 18: 1667-77
Thomsen ND, Berger JM. (2009) Running in reverse: the structural basis for translocation polarity in hexameric helicases. Cell. 139: 523-34
Thomsen ND, Berger JM. (2008) Structural frameworks for considering microbial protein- and nucleic acid-dependent motor ATPases. Molecular Microbiology. 69: 1071-90
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