David Akopian

Affiliations: 
2014 Biochemistry and Molecular Biophysics California Institute of Technology, Pasadena, CA 
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"David Akopian"
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Parents

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Shu-ou Shan grad student 2014 Caltech
 (Phospholipids and a protein-conducting channel regulate cotranslational protein targeting.)
Michael Rape post-doc 2014- UC Berkeley and HHMI
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Publications

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Akopian D, McGourty CA, Rapé M. (2022) Co-adaptor driven assembly of a CUL3 E3 ligase complex. Molecular Cell. 82: 585-597.e11
Mena EL, Jevtić P, Greber BJ, et al. (2020) Structural basis for dimerization quality control. Nature
Oh E, Akopian D, Rape M. (2018) Principles of Ubiquitin-Dependent Signaling. Annual Review of Cell and Developmental Biology
Akopian D, Rape M. (2017) Conducting the finale of DNA replication. Genes & Development. 31: 226-227
Roberts AM, Miyamoto DK, Huffman TR, et al. (2017) Chemoproteomic Screening of Covalent Ligands Reveals UBA5 as a Novel Pancreatic Cancer Target. Acs Chemical Biology
McGourty CA, Akopian D, Walsh C, et al. (2016) Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. Cell. 167: 525-538.e14
Saraogi I, Akopian D, Shan SO. (2014) Regulation of cargo recognition, commitment, and unloading drives cotranslational protein targeting. The Journal of Cell Biology. 205: 693-706
Akopian D, Shen K, Zhang X, et al. (2013) Signal recognition particle: an essential protein-targeting machine. Annual Review of Biochemistry. 82: 693-721
Akopian D, Dalal K, Shen K, et al. (2013) SecYEG activates GTPases to drive the completion of cotranslational protein targeting. The Journal of Cell Biology. 200: 397-405
Shen K, Arslan S, Akopian D, et al. (2013) Activated GTPase Movement on SRP RNA Drives Cotranslational Protein Targeting Biophysical Journal. 104: 419a
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