Mark Jason Seierstad - Publications

Affiliations: 
1994-2000 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 

4/26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Leonard KA, Madge LA, Krawczuk PJ, Wang A, Kreutter KD, Bacani GM, Chai W, Smith RC, Tichenor MS, Harris MC, Malaviya R, Seierstad M, Johnson ME, Venable JD, Kim S, et al. Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease. Journal of Medicinal Chemistry. PMID 32134643 DOI: 10.1021/Acs.Jmedchem.9B01439  0.342
2003 Price JM, Nizzi KE, Campbell JL, Kenttämaa HI, Seierstad M, Cramer CJ. Experimental and theoretical characterization of the 3,5-didehydrobenzoate anion: a negatively charged meta-benzyne. Journal of the American Chemical Society. 125: 131-40. PMID 12515514 DOI: 10.1021/Ja021112O  0.314
1999 Denmark SE, Seierstad M. Tandem Cycloaddition Chemistry of Nitroalkenes: Probing the Remarkable Stereochemical Influence of the Lewis Acid. The Journal of Organic Chemistry. 64: 1610-1619. PMID 11674226 DOI: 10.1021/Jo9820869  0.369
1999 Denmark SE, Seierstad M, Herbert B. Tandem Cycloaddition Chemistry of Nitroalkenes: Preparative and Theoretical Studies on the Stereochemical Course of [3 + 2] Cycloaddition of Cyclic Nitronates. The Journal of Organic Chemistry. 64: 884-901. PMID 11674161 DOI: 10.1021/Jo9818374  0.396
Low-probability matches (unlikely to be authored by this person)
2002 Seierstad M, Kinsinger CR, Cramer CJ. Design optimization of 1,3-diphospha-2,4-diboretane diradicals. Angewandte Chemie (International Ed. in English). 41: 3894-6. PMID 12386883 DOI: 10.1002/1521-3773(20021018)41:20<3894::Aid-Anie3894>3.0.Co;2-Z  0.255
2020 Keith JM, Jones W, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz M, Scott BP, Wilson SJ, Luo L, Wennerholm M, Chang L, Rizzolio M, Rynberg R, Chaplan S, et al. Heteroarylureas with Fused Bicyclic Diamine Cores as Inhibitors of Fatty Acid Amide Hydrolase. Bioorganic & Medicinal Chemistry Letters. 127463. PMID 32784090 DOI: 10.1016/j.bmcl.2020.127463  0.243
2019 Savall BM, Wu D, Swanson DM, Seierstad M, Wu N, Vives Martinez J, García Olmos B, Lord B, Coe K, Koudriakova T, Lovenberg TW, Carruthers NI, Maher MP, Ameriks MK. Discovery of Imidazo[1,2-]pyrazines and Pyrazolo[1,5-]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators. Acs Medicinal Chemistry Letters. 10: 267-272. PMID 30891124 DOI: 10.1021/acsmedchemlett.8b00599  0.222
2021 Tichenor MS, Wiener JJM, Rao NL, Pooley Deckhut C, Barbay JK, Kreutter KD, Bacani GM, Wei J, Chang L, Murrey HE, Wang W, Ahn K, Huber M, Rex E, Coe KJ, ... ... Seierstad M, et al. Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity. Acs Medicinal Chemistry Letters. 12: 782-790. PMID 34055226 DOI: 10.1021/acsmedchemlett.1c00044  0.22
2012 Tichenor MS, Keith JM, Jones WM, Pierce JM, Merit J, Hawryluk N, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Wilson SJ, Wennerholm ML, Woestenborghs F, Beerens D, Luo L, et al. Heteroaryl urea inhibitors of fatty acid amide hydrolase: structure-mutagenicity relationships for arylamine metabolites. Bioorganic & Medicinal Chemistry Letters. 22: 7357-62. PMID 23141911 DOI: 10.1016/j.bmcl.2012.10.076  0.216
2008 Keith JM, Apodaca R, Xiao W, Seierstad M, Pattabiraman K, Wu J, Webb M, Karbarz MJ, Brown S, Wilson S, Scott B, Tham CS, Luo L, Palmer J, Wennerholm M, et al. Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 18: 4838-43. PMID 18693015 DOI: 10.1016/j.bmcl.2008.07.081  0.213
2014 Keith JM, Hawryluk N, Apodaca RL, Chambers A, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Luo L, Wennerholm ML, Chang L, Rizzolio M, et al. 1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 24: 1280-4. PMID 24513048 DOI: 10.1016/j.bmcl.2014.01.064  0.202
2014 Keith JM, Jones WM, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Luo L, Wennerholm ML, Chang L, Brown SM, Rizzolio M, Rynberg R, et al. Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 24: 737-41. PMID 24433863 DOI: 10.1016/j.bmcl.2013.12.113  0.196
2015 Keith JM, Jones WM, Tichenor M, Liu J, Seierstad M, Palmer JA, Webb M, Karbarz M, Scott BP, Wilson SJ, Luo L, Wennerholm ML, Chang L, Rizzolio M, Rynberg R, et al. Preclinical Characterization of the FAAH Inhibitor JNJ-42165279. Acs Medicinal Chemistry Letters. 6: 1204-8. PMID 26713105 DOI: 10.1021/acsmedchemlett.5b00353  0.187
2008 Timmons A, Seierstad M, Apodaca R, Epperson M, Pippel D, Brown S, Chang L, Scott B, Webb M, Chaplan SR, Breitenbucher JG. Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH) Bioorganic and Medicinal Chemistry Letters. 18: 2109-2113. PMID 18289847 DOI: 10.1016/j.bmcl.2008.01.091  0.186
2012 Keith JM, Apodaca R, Tichenor M, Xiao W, Jones W, Pierce J, Seierstad M, Palmer J, Webb M, Karbarz M, Scott B, Wilson S, Luo L, Wennerholm M, Chang L, et al. Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate. Acs Medicinal Chemistry Letters. 3: 823-7. PMID 24900385 DOI: 10.1021/ml300186g  0.186
2016 Keith JM, Tichenor MS, Apodaca RL, Xiao W, Jones WM, Seierstad M, Pierce JM, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Wennerholm ML, Rizzolio M, Rynberg R, et al. The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27189675 DOI: 10.1016/j.bmcl.2016.05.001  0.18
2018 Ravula S, Savall BM, Wu N, Lord B, Coe K, Wang K, Seierstad M, Swanson DM, Ziff J, Nguyen M, Leung P, Rynberg R, La D, Pippel DJ, Koudriakova T, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. Acs Medicinal Chemistry Letters. 9: 821-826. PMID 30128074 DOI: 10.1021/acsmedchemlett.8b00215  0.177
2007 Keith JM, Gomez LA, Letavic MA, Ly KS, Jablonowski JA, Seierstad M, Barbier AJ, Wilson SJ, Boggs JD, Fraser IC, Mazur C, Lovenberg TW, Carruthers NI. Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore. Bioorganic & Medicinal Chemistry Letters. 17: 702-6. PMID 17107798 DOI: 10.1016/j.bmcl.2006.10.089  0.158
2018 Saha A, Shih AY, Mirzadegan T, Seierstad M. Predicting the Binding of Fatty Acid Amide Hydrolase Inhibitors by Free Energy Perturbation (FEP). Journal of Chemical Theory and Computation. PMID 30289722 DOI: 10.1021/Acs.Jctc.8B00672  0.148
2021 Seierstad M, Tichenor MS, DesJarlais RL, Na J, Bacani GM, Chung M, Mercado-Marin EV, Steffens HC, Mirzadegan T. Novel Reagent Space: Identifying Unorderable but Readily Synthesizable Building Blocks. Acs Medicinal Chemistry Letters. 12: 1853-1860. PMID 34795876 DOI: 10.1021/acsmedchemlett.1c00340  0.12
2011 Hack MD, Rassokhin DN, Buyck C, Seierstad M, Skalkin A, ten Holte P, Jones TK, Mirzadegan T, Agrafiotis DK. Library enhancement through the wisdom of crowds. Journal of Chemical Information and Modeling. 51: 3275-86. PMID 22035213 DOI: 10.1021/ci200446y  0.12
2009 Seierstad M, Breitenbucher JG. Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors. Journal of Medicinal Chemistry. 51: 7327-43. PMID 18983142 DOI: 10.1021/jm800311k  0.12
2006 Seierstad M, Agrafiotis DK. A QSAR model of HERG binding using a large, diverse, and internally consistent training set. Chemical Biology & Drug Design. 67: 284-96. PMID 16629826 DOI: 10.1111/j.1747-0285.2006.00379.x  0.12
2017 Maher MP, Matta JA, Gu S, Seierstad M, Bredt DS. Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins. Neuron. 96: 989-1001. PMID 29216460 DOI: 10.1016/j.neuron.2017.10.001  0.1
2011 Swanson DM, Wong VD, Jablonowski JA, Shah C, Rudolph DA, Dvorak CA, Seierstad M, Dvorak LK, Morton K, Nepomuceno D, Atack JR, Bonaventure P, Lovenberg TW, Carruthers NI. The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor. Bioorganic & Medicinal Chemistry Letters. 21: 5552-6. PMID 21802951 DOI: 10.1016/j.bmcl.2011.06.136  0.081
2007 Kuei C, Sutton S, Bonaventure P, Pudiak C, Shelton J, Zhu J, Nepomuceno D, Wu J, Chen J, Kamme F, Seierstad M, Hack MD, Bathgate RA, Hossain MA, Wade JD, et al. R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization. The Journal of Biological Chemistry. 282: 25425-35. PMID 17606621 DOI: 10.1074/jbc.M701416200  0.056
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