Thomas J. Greshock, Ph.D. - Publications

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Natural products synthesis

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Greshock TJ, Sanders JM, Drolet RE, Rajapakse HA, Chang RK, Kim B, Rada VL, Tiscia HE, Su H, Lai MT, Sur SM, Sanchez RI, Bilodeau MT, Renger JJ, Kern JT, et al. Potent, selective and orally bioavailable leucine-rich repeat kinase 2 (LRRK2) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27106707 DOI: 10.1016/j.bmcl.2016.04.021  1
2012 Kuduk SD, Chang RK, Greshock TJ, Ray WJ, Ma L, Wittmann M, Seager MA, Koeplinger KA, Thompson CD, Hartman GD, Bilodeau MT. Identification of amides as carboxylic Acid surrogates for quinolizidinone-based m1 positive allosteric modulators. Acs Medicinal Chemistry Letters. 3: 1070-4. PMID 24900430 DOI: 10.1021/ml300280g  1
2011 Finefield JM, Greshock TJ, Sherman DH, Tsukamoto S, Williams RM. Notoamide E: Biosynthetic incorporation into notoamides C and D in cultures of Aspergillus versicolor NRRL 35600. Tetrahedron Letters. 52: 1987-1989. PMID 22140279 DOI: 10.1016/j.tetlet.2011.02.078  1
2011 Finefield JM, Kato H, Greshock TJ, Sherman DH, Tsukamoto S, Williams RM. Biosynthetic studies of the notoamides: isotopic synthesis of stephacidin A and incorporation into notoamide B and sclerotiamide. Organic Letters. 13: 3802-5. PMID 21714564 DOI: 10.1021/ol201284y  1
2011 Kuduk SD, Chang RK, Di Marco CN, Pitts DR, Greshock TJ, Ma L, Wittmann M, Seager MA, Koeplinger KA, Thompson CD, Hartman GD, Bilodeau MT, Ray WJ. Discovery of a selective allosteric M1 receptor modulator with suitable development properties based on a quinolizidinone carboxylic acid scaffold. Journal of Medicinal Chemistry. 54: 4773-80. PMID 21682298 DOI: 10.1021/jm200400m  1
2010 Namba K, Inai M, Sundermeier U, Greshock TJ, Williams RM. Synthetic Studies on Palau'amine. Construction of the Cyclopentane Core via an Asymmetric 1,3-Dipolar Cycloaddition. Tetrahedron Letters. 51: 6557-6559. PMID 21286237 DOI: 10.1016/j.tetlet.2010.10.037  1
2010 Ding Y, de Wet JR, Cavalcoli J, Li S, Greshock TJ, Miller KA, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH. Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp. Journal of the American Chemical Society. 132: 12733-40. PMID 20722388 DOI: 10.1021/ja1049302  1
2009 Tsukamoto S, Kato H, Greshock TJ, Hirota H, Ohta T, Williams RM. Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp. Journal of the American Chemical Society. 131: 3834-5. PMID 19292484 DOI: 10.1021/ja810029b  1
2009 Tsukamoto S, Kawabata T, Kato H, Greshock TJ, Hirota H, Ohta T, Williams RM. Isolation of antipodal (-)-versicolamide B and notoamides L-N from a marine-derived Aspergillus sp. Organic Letters. 11: 1297-300. PMID 19281134 DOI: 10.1021/ol900071c  1
2009 Chang RK, Di Marco CN, Pitts DR, Greshock TJ, Kuduk SD. Preparation of 4-heteroaryl-4-cyanopiperidines via SNAr substitution reactions Tetrahedron Letters. 50: 6303-6306. DOI: 10.1016/j.tetlet.2009.08.123  1
2008 Miller KA, Figueroa M, Valente MW, Greshock TJ, Mata R, Williams RM. Calmodulin inhibitory activity of the malbrancheamides and various analogs. Bioorganic & Medicinal Chemistry Letters. 18: 6479-81. PMID 18986806 DOI: 10.1016/j.bmcl.2008.10.057  1
2008 Ding Y, Greshock TJ, Miller KA, Sherman DH, Williams RM. Premalbrancheamide: synthesis, isotopic labeling, biosynthetic incorporation, and detection in cultures of Malbranchea aurantiaca. Organic Letters. 10: 4863-6. PMID 18844365 DOI: 10.1021/ol8019633  1
2008 Ding Y, Gruschow S, Greshock TJ, Finefield JM, Sherman DH, Williams RM. Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: biosynthetic implications. Journal of Natural Products. 71: 1574-8. PMID 18754595 DOI: 10.1021/np800292n  1
2008 Greshock TJ, Grubbs AW, Jiao P, Wicklow DT, Gloer JB, Williams RM. Isolation, structure elucidation, and biomimetic total synthesis of versicolamide B, and the isolation of antipodal (-)-stephacidin A and (+)-notoamide B from Aspergillus versicolor NRRL 35600. Angewandte Chemie (International Ed. in English). 47: 3573-7. PMID 18389509 DOI: 10.1002/anie.200800106  1
2008 Miller KA, Welch TR, Greshock TJ, Ding Y, Sherman DH, Williams RM. Biomimetic total synthesis of malbrancheamide and malbrancheamide B. The Journal of Organic Chemistry. 73: 3116-9. PMID 18345688 DOI: 10.1021/jo800116y  1
2008 Greshock TJ, Johns DM, Noguchi Y, Williams RM. Improved total synthesis of the potent HDAC inhibitor FK228 (FR-901228). Organic Letters. 10: 613-6. PMID 18205373 DOI: 10.1021/ol702957z  1
2007 Greshock TJ, Grubbs AW, Williams RM. Concise, Biomimetic Total Synthesis of d,l-Marcfortine C. Tetrahedron. 63: 6124-6130. PMID 18596842 DOI: 10.1016/j.tet.2007.03.016  1
2007 Greshock TJ, Williams RM. Improved biomimetic total synthesis of D,L-stephacidin A. Organic Letters. 9: 4255-8. PMID 17854197 DOI: 10.1021/ol701845t  1
2007 Greshock TJ, Grubbs AW, Tsukamoto S, Williams RM. A concise, biomimetic total synthesis of stephacidin A and notoamide B. Angewandte Chemie (International Ed. in English). 46: 2262-5. PMID 17304610 DOI: 10.1002/anie.200604378  1
2006 Greshock TJ, Funk RL. An approach to the total synthesis of welwistatin. Organic Letters. 8: 2643-5. PMID 16737334 DOI: 10.1021/ol0608799  1
2006 Greshock TJ, Funk RL. Synthesis of indoles via 6pi-electrocyclic ring closures of trienecarbamates. Journal of the American Chemical Society. 128: 4946-7. PMID 16608316 DOI: 10.1021/ja060282o  1
2006 Greshock TJ, Funk RL. 6-(2-Haloethyl)-2,2-dimethyl-4H-1,3-dioxins: versatile haloethyl vinyl ketone equivalents for carbocycle construction Tetrahedron Letters. 47: 5437-5439. DOI: 10.1016/j.tetlet.2006.05.171  1
2002 Greshock TJ, Funk RL. 6-Bromomethyl-4H-1,3-dioxin: a versatile bromomethyl vinyl ketone equivalent for heterocycle and carbocycle construction. Journal of the American Chemical Society. 124: 754-5. PMID 11817942 DOI: 10.1021/ja0123554  1
2001 Greshock TJ, Funk RL. Total synthesis of (+/-)-lepadiformine via an amidoacrolein cycloaddition. Organic Letters. 3: 3511-4. PMID 11678695  1
2001 Greshock TJ, Funk RL. Total synthesis of (±)-lepadiformine via an amidoacrolein cycloaddition Organic Letters. 3: 3511-3514. DOI: 10.1021/ol0165903  1
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