| Year |
Citation |
Score |
| 2024 |
Phan TN, Park KP, Shum D, No JH. Identification of PEX5-PTS1 Interaction Inhibitors through Fluorescence Polarization-Based High-Throughput Screening. Molecules (Basel, Switzerland). 29. PMID 38675653 DOI: 10.3390/molecules29081835 |
0.307 |
|
| 2023 |
Hassan AHE, Alam MM, Phan TN, Baek KH, Lee H, Cho SB, Lee CH, Kim YJ, No JH, Lee YS. Repurposing of conformationally-restricted cyclopentane-based AKT-inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine. Bioorganic Chemistry. 141: 106890. PMID 37783099 DOI: 10.1016/j.bioorg.2023.106890 |
0.319 |
|
| 2023 |
Stampolaki M, Malwal SR, Alvarez-Cabrera N, Gao Z, Moniruzzaman M, Babii SO, Naziris N, Rey-Cibati A, Valladares-Delgado M, Turcu AL, Baek KH, Phan TN, Lee H, Alcaraz M, Watson S, ... ... No JH, et al. Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against and Malaria Parasites. Acs Infectious Diseases. PMID 36706233 DOI: 10.1021/acsinfecdis.2c00537 |
0.516 |
|
| 2022 |
Phan TN, Park KP, Benítez D, Comini MA, Shum D, No JH. Discovery of novel Leishmania major trypanothione synthetase inhibitors by high-throughput screening. Biochemical and Biophysical Research Communications. 637: 308-313. PMID 36413853 DOI: 10.1016/j.bbrc.2022.11.044 |
0.33 |
|
| 2022 |
Baek KH, Phan TN, Malwal SR, Lee H, Li ZH, Moreno SNJ, Oldfield E, No JH. In Vivo Efficacy of SQ109 against , spp. and and In Vitro Activity of SQ109 Metabolites. Biomedicines. 10. PMID 35327472 DOI: 10.3390/biomedicines10030670 |
0.428 |
|
| 2022 |
Benítez D, Franco J, Sardi F, Leyva A, Durán R, Choi G, Yang G, Kim T, Kim N, Heo J, Kim K, Lee H, Choi I, Radu C, Shum D, ... No JH, et al. Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening. Journal of Enzyme Inhibition and Medicinal Chemistry. 37: 912-929. PMID 35306933 DOI: 10.1080/14756366.2022.2045590 |
0.379 |
|
| 2021 |
Lee H, Baek KH, Phan TN, Park IS, Lee S, Kim J, No JH. Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits. Biochemical and Biophysical Research Communications. 569: 193-198. PMID 34256188 DOI: 10.1016/j.bbrc.2021.07.019 |
0.348 |
|
| 2020 |
Baek KH, Piel L, Rosazza T, Prina E, Späth GF, No JH. Infectivity and Drug Susceptibility Profiling of Different -Host Cell Combinations. Pathogens (Basel, Switzerland). 9. PMID 32443883 DOI: 10.3390/Pathogens9050393 |
0.355 |
|
| 2020 |
Phan TN, Baek KH, Lee N, Byun SY, Shum D, No JH. In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against and . Molecules (Basel, Switzerland). 25. PMID 32340370 DOI: 10.3390/Molecules25081980 |
0.431 |
|
| 2019 |
Zahedifard F, Lee H, No JH, Salimi M, Seyed N, Asoodeh A, Rafati S. Comparative study of different forms of Jellein antimicrobial peptide on Leishmania parasite. Experimental Parasitology. 107823. PMID 31862270 DOI: 10.1016/J.Exppara.2019.107823 |
0.308 |
|
| 2017 |
O'Dowd B, Williams S, Wang H, No JH, Rao G, Wang W, McCammon JA, Cramer SP, Oldfield E. Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non-Diphosphate Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 28253432 DOI: 10.1002/Cbic.201700052 |
0.708 |
|
| 2017 |
O'Dowd B, Williams S, Wang H, No JH, Rao G, Wang W, McCammon JA, Cramer SP, Oldfield E. Inside Cover: Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non-diphosphate Inhibitors (ChemBioChem 10/2017) Chembiochem. 18: 882-882. DOI: 10.1002/Cbic.201700218 |
0.679 |
|
| 2016 |
Yang G, Lee N, Ioset JR, No JH. Evaluation of Parameters Impacting Drug Susceptibility in Intracellular Trypanosoma cruzi Assay Protocols. Journal of Biomolecular Screening. PMID 27729503 DOI: 10.1177/1087057116673796 |
0.388 |
|
| 2016 |
Yang G, Choi G, No JH. Antileishmanial Mechanism of Diamidines: Targeting Kinetoplasts. Antimicrobial Agents and Chemotherapy. PMID 27600039 DOI: 10.1128/Aac.01129-16 |
0.385 |
|
| 2016 |
Sun YN, No JH, Lee GY, Li W, Yang SY, Yang G, Schmidt TJ, Kang JS, Kim YH. Phenolic Constituents of Medicinal Plants with Activity against Trypanosoma brucei. Molecules (Basel, Switzerland). 21. PMID 27077842 DOI: 10.3390/Molecules21040480 |
0.383 |
|
| 2016 |
Durieu E, Prina E, Leclercq O, Oumata N, Gaboriaud-Kolar N, Vougogiannopoulou K, Aulner N, Defontaine A, No JH, Ruchaud S, Skaltsounis AL, Galons H, Späth GF, Meijer L, Rachidi N. From drug screening to target deconvolution: A target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with anti-leishmanial activity. Antimicrobial Agents and Chemotherapy. PMID 26902771 DOI: 10.1128/Aac.00021-16 |
0.414 |
|
| 2015 |
No JH. Visceral leishmaniasis: Revisiting current treatments and approaches for future discoveries. Acta Tropica. 155: 113-123. PMID 26748356 DOI: 10.1016/J.Actatropica.2015.12.016 |
0.319 |
|
| 2015 |
Yang G, Zhu W, Kim K, Byun SY, Choi G, Wang K, Cha JS, Cho HS, Oldfield E, No JH. Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates: An In Vitro and In Vivo Investigation. Antimicrobial Agents and Chemotherapy. PMID 26392508 DOI: 10.1128/Aac.01873-15 |
0.599 |
|
| 2015 |
Yang G, Zhu W, Wang Y, Huang G, Byun S, Choi G, Li K, Huang Z, Docampo R, Oldfield E, No JH. In Vitro and In Vivo Activity of Multi-Target Inhibitors Against Trypanosoma brucei. Acs Infectious Diseases. 1: 388-398. PMID 26295062 DOI: 10.1021/Acsinfecdis.5B00068 |
0.581 |
|
| 2015 |
Li K, Wang Y, Yang G, Byun S, Rao G, Shoen C, Yang H, Gulati A, Crick DC, Cynamon M, Huang G, Docampo R, No JH, Oldfield E. Oxa, Thia, Heterocycle, and Carborane Analogues of SQ109: Bacterial and Protozoal Cell Growth Inhibitors. Acs Infectious Diseases. 1: 215-221. PMID 26258172 DOI: 10.1021/Acsinfecdis.5B00026 |
0.559 |
|
| 2014 |
Thao NP, No JH, Luyen BT, Yang G, Byun SY, Goo J, Kim KT, Cuong NX, Nam NH, Van Minh C, Schmidt TJ, Kang JS, Kim YH. Secondary metabolites from Vietnamese marine invertebrates with activity against Trypanosoma brucei and T. cruzi. Molecules (Basel, Switzerland). 19: 7869-80. PMID 24962391 DOI: 10.3390/Molecules19067869 |
0.343 |
|
| 2014 |
Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, et al. Multitarget drug discovery for tuberculosis and other infectious diseases. Journal of Medicinal Chemistry. 57: 3126-39. PMID 24568559 DOI: 10.1021/Jm500131S |
0.632 |
|
| 2013 |
Cruz DJ, Bonotto RM, Gomes RG, da Silva CT, Taniguchi JB, No JH, Lombardot B, Schwartz O, Hansen MA, Freitas-Junior LH. Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library. Plos Neglected Tropical Diseases. 7: e2471. PMID 24205414 DOI: 10.1371/Journal.Pntd.0002471 |
0.4 |
|
| 2013 |
Zhang Y, Zhu W, Liu YL, Wang H, Wang K, Li K, No JH, Ayong L, Gulati A, Pang R, Freitas-Junior L, Morita CT, Old-Field E. Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis. Acs Medicinal Chemistry Letters. 4: 423-427. PMID 23610597 DOI: 10.1021/Ml4000436 |
0.444 |
|
| 2013 |
Cruz DJ, Koishi AC, Taniguchi JB, Li X, Milan Bonotto R, No JH, Kim KH, Baek S, Kim HY, Windisch MP, Pamplona Mosimann AL, de Borba L, Liuzzi M, Hansen MA, Duarte dos Santos CN, et al. High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses. Plos Neglected Tropical Diseases. 7: e2073. PMID 23437413 DOI: 10.1371/Journal.Pntd.0002073 |
0.343 |
|
| 2013 |
Zhang Y, Zhu W, Liu YL, Wang H, Wang K, Li K, No JH, Ayong L, Gulati A, Pang R, Freitas-Junior L, Morita CT, Oldfield E. Chemo-immunotherapeutic antimalarials targeting isoprenoid biosynthesis Acs Medicinal Chemistry Letters. 4: 423-427. DOI: 10.1021/ml4000436 |
0.383 |
|
| 2012 |
No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 4058-63. PMID 22392982 DOI: 10.1073/Pnas.1118215109 |
0.693 |
|
| 2010 |
Singh AP, Zhang Y, No JH, Docampo R, Nussenzweig V, Oldfield E. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrobial Agents and Chemotherapy. 54: 2987-93. PMID 20457823 DOI: 10.1128/Aac.00198-10 |
0.54 |
|
| 2010 |
Wang K, Wang W, No JH, Zhang Y, Zhang Y, Oldfield E. Inhibition of the Fe(4)S(4)-cluster-containing protein IspH (LytB): electron paramagnetic resonance, metallacycles, and mechanisms. Journal of the American Chemical Society. 132: 6719-27. PMID 20426416 DOI: 10.1021/Ja909664J |
0.713 |
|
| 2010 |
Wang W, Wang K, Liu YL, No JH, Li J, Nilges MJ, Oldfield E. Bioorganometallic mechanism of action, and inhibition, of IspH. Proceedings of the National Academy of Sciences of the United States of America. 107: 4522-7. PMID 20173096 DOI: 10.1073/Pnas.0911087107 |
0.714 |
|
| 2010 |
Zhang Y, Cao R, Yin F, Lin FY, Wang H, Krysiak K, No JH, Mukkamala D, Houlihan K, Li J, Morita CT, Oldfield E. Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulators. Angewandte Chemie (International Ed. in English). 49: 1136-8. PMID 20039246 DOI: 10.1002/Anie.200905933 |
0.723 |
|
| 2009 |
Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. Journal of Medicinal Chemistry. 52: 3869-80. PMID 19456099 DOI: 10.1021/Jm9001764 |
0.692 |
|
| 2009 |
Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, et al. Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. Journal of the American Chemical Society. 131: 5153-62. PMID 19309137 DOI: 10.1021/Ja808285E |
0.707 |
|
| 2008 |
Mukkamala D, No JH, Cass LM, Chang TK, Oldfield E. Bisphosphonate inhibition of a Plasmodium farnesyl diphosphate synthase and a general method for predicting cell-based activity from enzyme data. Journal of Medicinal Chemistry. 51: 7827-33. PMID 19053772 DOI: 10.1021/Jm8009074 |
0.505 |
|
| 2008 |
Rekittke I, Wiesner J, Röhrich R, Demmer U, Warkentin E, Xu W, Troschke K, Hintz M, No JH, Duin EC, Oldfield E, Jomaa H, Ermler U. Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. Journal of the American Chemical Society. 130: 17206-7. PMID 19035630 DOI: 10.1021/Ja806668Q |
0.529 |
|
| 2008 |
K-M Chen C, Hudock MP, Zhang Y, Guo RT, Cao R, No JH, Liang PH, Ko TP, Chang TH, Chang SC, Song Y, Axelson J, Kumar A, Wang AH, Oldfield E. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. Journal of Medicinal Chemistry. 51: 5594-607. PMID 18800762 DOI: 10.1021/Jm800325Y |
0.74 |
|
| Show low-probability matches. |