Sarah Heilshorn, Ph.D. - Publications

Stanford University, Palo Alto, CA 
 2004 California Institute of Technology, Pasadena, CA 
Materials Science and Engineering, Chemical Engineering, Bioengineering

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Navarro RS, Huang MS, Roth JG, Hubka KM, Long CM, Enejder A, Heilshorn SC. Tuning Polymer Hydrophilicity to Regulate Gel Mechanics and Encapsulated Cell Morphology. Advanced Healthcare Materials. e2200011. PMID 35373510 DOI: 10.1002/adhm.202200011  0.767
2022 Hull SM, Brunel LG, Heilshorn SC. 3D Bioprinting of Cell-Laden Hydrogels for Improved Biological Functionality. Advanced Materials (Deerfield Beach, Fla.). 34: e2103691. PMID 34672027 DOI: 10.1002/adma.202103691  0.308
2021 Roth JG, Huang MS, Li TL, Feig VR, Jiang Y, Cui B, Greely HT, Bao Z, Paşca SP, Heilshorn SC. Advancing models of neural development with biomaterials. Nature Reviews. Neuroscience. PMID 34376834 DOI: 10.1038/s41583-021-00496-y  0.728
2021 Seymour AJ, Shin S, Heilshorn SC. 3D Printing of Microgel Scaffolds with Tunable Void Fraction to Promote Cell Infiltration. Advanced Healthcare Materials. e2100644. PMID 34342179 DOI: 10.1002/adhm.202100644  0.318
2021 Hunt DR, Klett KC, Mascharak S, Wang H, Gong D, Lou J, Li X, Cai PC, Suhar RA, Co JY, LeSavage BL, Foster AA, Guan Y, Amieva MR, Peltz G, ... ... Heilshorn SC, et al. Engineered Matrices Enable the Culture of Human Patient-Derived Intestinal Organoids. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2004705. PMID 34026461 DOI: 10.1002/advs.202004705  0.601
2021 Hull SM, Lindsay CD, Brunel LG, Shiwarski DJ, Tashman JW, Roth JG, Myung D, Feinberg AW, Heilshorn SC. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials. 31. PMID 33613150 DOI: 10.1002/adfm.202007983  0.757
2021 Krajina BA, LeSavage BL, Roth JG, Zhu AW, Cai PC, Spakowitz AJ, Heilshorn SC. Microrheology reveals simultaneous cell-mediated matrix stiffening and fluidization that underlie breast cancer invasion. Science Advances. 7. PMID 33597244 DOI: 10.1126/sciadv.abe1969  0.707
2020 Madl CM, LeSavage BL, Khariton M, Heilshorn SC. Neural Progenitor Cells Alter Chromatin Organization and Neurotrophin Expression in Response to 3D Matrix Degradability. Advanced Healthcare Materials. e2000754. PMID 32743903 DOI: 10.1002/adhm.202000754  0.318
2020 Duarte Campos DF, Lindsay CD, Roth JG, LeSavage BL, Seymour AJ, Krajina BA, Ribeiro R, Costa PF, Blaeser A, Heilshorn SC. Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms. Frontiers in Bioengineering and Biotechnology. 8: 374. PMID 32411691 DOI: 10.3389/fbioe.2020.00374  0.743
2019 Lindsay CD, Roth JG, LeSavage BL, Heilshorn SC. Bioprinting of stem cell expansion lattices. Acta Biomaterialia. PMID 31096043 DOI: 10.1016/j.actbio.2019.05.014  0.719
2019 Madl CM, LeSavage BL, Dewi RE, Lampe KJ, Heilshorn SC. Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1801716. PMID 30828535 DOI: 10.1002/Advs.201801716  0.741
2019 Natarajan S, Foreman K, Soriano M, Shehade H, Fregoso D, Eggold J, Rosen NS, Heilshorn S, Krieg AJ, Krishnan V, Dorigo O, Sinha S, Fuh KC, Rankin EB. Abstract TMIM-081: THE HYPOXIC TUMOR-MESOTHELIAL NICHE PROMOTES OVARIAN CANCER METASTASIS THROUGH COLLAGEN REMODELING Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Tmim-081  0.316
2018 Madl CM, Heilshorn SC. Bioorthogonal Strategies for Engineering Extracellular Matrices. Advanced Functional Materials. 28. PMID 31558890 DOI: 10.1002/adfm.201706046  0.324
2018 Deming TJ, Klok HA, Armes SP, Becker ML, Champion JA, Chen EY, Heilshorn SC, van Hest JCM, Irvine DJ, Johnson JA, Kiessling LL, Maynard HD, de la Cruz MO, Sullivan MO, Tirrell MV, et al. Polymers at the Interface with Biology. Biomacromolecules. 19: 3151-3162. PMID 30099879 DOI: 10.1021/Acs.Biomac.8B01029  0.7
2018 LeSavage BL, Suhar NA, Madl CM, Heilshorn SC. Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D. Journal of Visualized Experiments : Jove. PMID 29863669 DOI: 10.3791/57739  0.383
2018 Foster AA, Dewi RE, Cai L, Hou L, Strassberg Z, Alcazar CA, Heilshorn SC, Huang NF. Protein-engineered hydrogels enhance the survival of induced pluripotent stem cell-derived endothelial cells for treatment of peripheral arterial disease. Biomaterials Science. PMID 29406542 DOI: 10.1039/C7Bm00883J  0.637
2018 Gai H, Gras~Pena R, Verma Y, Fateh V, Ikeda K, Dejene B, Min D, Wang J, Swigut T, Weinberg KI, Hollander GA, Heilshorn S, Roncarolo M, Sebastiano V, Weinacht KG. Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis Blood. 132: 5092-5092. DOI: 10.1182/Blood-2018-99-117499  0.44
2017 Wang H, Zhu D, Paul A, Cai L, Enejder A, Yang F, Heilshorn SC. Covalently adaptable elastin-like protein - hyaluronic acid (ELP - HA) hybrid hydrogels with secondary thermoresponsive crosslinking for injectable stem cell delivery. Advanced Functional Materials. 27. PMID 33041740 DOI: 10.1002/adfm.201605609  0.359
2017 Madl CM, LeSavage BL, Dewi RE, Dinh CB, Stowers RS, Khariton M, Lampe KJ, Nguyen D, Chaudhuri O, Enejder A, Heilshorn SC. Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling. Nature Materials. PMID 29115291 DOI: 10.1038/Nmat5020  0.725
2017 Foster AA, Marquardt LM, Heilshorn SC. The Diverse Roles of Hydrogel Mechanics in Injectable Stem Cell Transplantation. Current Opinion in Chemical Engineering. 15: 15-23. PMID 29085771 DOI: 10.1016/j.coche.2016.11.003  0.573
2017 Dubbin K, Tabet A, Heilshorn S. Quantitative criteria to benchmark new and existing bio-inks for cell compatibility. Biofabrication. PMID 28812982 DOI: 10.1088/1758-5090/Aa869F  0.755
2017 Fernandes Cunha GM, Lee HJ, Kumar A, Kreymerman A, Heilshorn SC, Myung D. Immobilization of growth factors to collagen surfaces using visible light. Biomacromolecules. PMID 28799757 DOI: 10.1021/Acs.Biomac.7B00838  0.379
2017 Steele AN, Cai L, Truong VN, Edwards BB, Goldstone AB, Eskandari A, Mitchell AC, Marquardt LM, Foster AA, Cochran JR, Heilshorn SC, Woo YJ. A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. Biotechnology and Bioengineering. PMID 28574594 DOI: 10.1002/Bit.26345  0.549
2017 DiMarco RL, Hunt DR, Dewi RE, Heilshorn SC. Improvement of paracellular transport in the Caco-2 drug screening model using protein-engineered substrates. Biomaterials. 129: 152-162. PMID 28342321 DOI: 10.1016/j.biomaterials.2017.03.023  0.325
2017 Madl CM, Heilshorn SC. Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels. Bioconjugate Chemistry. PMID 28151642 DOI: 10.1021/acs.bioconjchem.6b00720  0.341
2017 Wang H, Zhu D, Paul A, Cai L, Enejder A, Yang F, Heilshorn SC. Hydrogels: Covalently Adaptable Elastin-Like Protein-Hyaluronic Acid (ELP-HA) Hybrid Hydrogels with Secondary Thermoresponsive Crosslinking for Injectable Stem Cell Delivery (Adv. Funct. Mater. 28/2017) Advanced Functional Materials. 27. DOI: 10.1002/ADFM.201770167  0.316
2016 Mascharak S, Benitez PL, Proctor AC, Madl CM, Hu KH, Dewi RE, Butte MJ, Heilshorn SC. YAP-dependent mechanotransduction is required for proliferation and migration on native-like substrate topography. Biomaterials. 115: 155-166. PMID 27889666 DOI: 10.1016/J.Biomaterials.2016.11.019  0.346
2016 Madl CM, Katz LM, Heilshorn SC. Bio-Orthogonally Crosslinked, Engineered Protein Hydrogels with Tunable Mechanics and Biochemistry for Cell Encapsulation. Advanced Functional Materials. 26: 3612-3620. PMID 27642274 DOI: 10.1002/adfm.201505329  0.414
2016 Quarta M, Brett JO, DiMarco R, De Morree A, Boutet SC, Chacon R, Gibbons MC, Garcia VA, Su J, Shrager JB, Heilshorn S, Rando TA. An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy. Nature Biotechnology. PMID 27240197 DOI: 10.1038/Nbt.3576  0.358
2015 Shamloo A, Mohammadaliha N, Heilshorn SC, Bauer AL. A Comparative Study of Collagen Matrix Density Effect on Endothelial Sprout Formation Using Experimental and Computational Approaches. Annals of Biomedical Engineering. PMID 26271521 DOI: 10.1007/S10439-015-1416-2  0.6
2015 Madl CM, Heilshorn SC. Matrix interactions modulate neurotrophin-mediated neurite outgrowth and pathfinding. Neural Regeneration Research. 10: 514-7. PMID 26170800 DOI: 10.4103/1673-5374.155426  0.309
2015 Romano NH, Lampe KJ, Xu H, Ferreira MM, Heilshorn SC. Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities. Small (Weinheim An Der Bergstrasse, Germany). 11: 722-30. PMID 25315156 DOI: 10.1002/Smll.201401574  0.718
2014 Wang H, Cai L, Paul A, Enejder A, Heilshorn SC. Hybrid elastin-like polypeptide-polyethylene glycol (ELP-PEG) hydrogels with improved transparency and independent control of matrix mechanics and cell ligand density. Biomacromolecules. 15: 3421-8. PMID 25111283 DOI: 10.1021/bm500969d  0.329
2014 Mulyasasmita W, Cai L, Dewi RE, Jha A, Ullmann SD, Luong RH, Huang NF, Heilshorn SC. Avidity-controlled hydrogels for injectable co-delivery of induced pluripotent stem cell-derived endothelial cells and growth factors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 191: 71-81. PMID 24848744 DOI: 10.1016/J.Jconrel.2014.05.015  0.332
2014 Cai L, Dinh CB, Heilshorn SC. One-pot Synthesis of Elastin-like Polypeptide Hydrogels with Grafted VEGF-Mimetic Peptides. Biomaterials Science. 2: 757-765. PMID 24729868 DOI: 10.1039/C3BM60293A  0.327
2014 Cai L, Heilshorn SC. Designing ECM-mimetic materials using protein engineering. Acta Biomaterialia. 10: 1751-60. PMID 24365704 DOI: 10.1016/j.actbio.2013.12.028  0.364
2014 Benitez PL, Heilshorn SC. Recombinant protein hydrogels for cell injection and transplantation Rsc Soft Matter. 48-72.  0.302
2013 Shamloo A, Manchandia M, Ferreira M, Mani M, Nguyen C, Jahn T, Weinberg K, Heilshorn S. Complex chemoattractive and chemorepellent Kit signals revealed by direct imaging of murine mast cells in microfluidic gradient chambers. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1076-85. PMID 23835699 DOI: 10.1039/C3Ib40025E  0.631
2013 Parisi-Amon A, Mulyasasmita W, Chung C, Heilshorn SC. Protein-engineered injectable hydrogel to improve retention of transplanted adipose-derived stem cells. Advanced Healthcare Materials. 2: 428-32. PMID 23184882 DOI: 10.1002/adhm.201200293  0.33
2013 Lampe KJ, Antaris AL, Heilshorn SC. Design of three-dimensional engineered protein hydrogels for tailored control of neurite growth. Acta Biomaterialia. 9: 5590-9. PMID 23128159 DOI: 10.1016/J.Actbio.2012.10.033  0.708
2012 Chung C, Lampe KJ, Heilshorn SC. Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels. Biomacromolecules. 13: 3912-6. PMID 23151175 DOI: 10.1021/Bm3015279  0.751
2012 Raphel J, Parisi-Amon A, Heilshorn S. Photoreactive elastin-like proteins for use as versatile bioactive materials and surface coatings. Journal of Materials Chemistry. 22: 19429-19437. PMID 23015764 DOI: 10.1039/C2JM31768K  0.327
2012 Lampe KJ, Heilshorn SC. Building stem cell niches from the molecule up through engineered peptide materials. Neuroscience Letters. 519: 138-46. PMID 22322073 DOI: 10.1016/J.Neulet.2012.01.042  0.724
2012 Aguado BA, Mulyasasmita W, Su J, Lampe KJ, Heilshorn SC. Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers. Tissue Engineering. Part A. 18: 806-15. PMID 22011213 DOI: 10.1089/Ten.Tea.2011.0391  0.731
2012 Shamloo A, Xu H, Heilshorn S. Mechanisms of vascular endothelial growth factor-induced pathfinding by endothelial sprouts in biomaterials. Tissue Engineering. Part A. 18: 320-30. PMID 21888475 DOI: 10.1089/Ten.Tea.2011.0323  0.632
2011 Romano NH, Sengupta D, Chung C, Heilshorn SC. Protein-engineered biomaterials: nanoscale mimics of the extracellular matrix. Biochimica Et Biophysica Acta. 1810: 339-49. PMID 20647034 DOI: 10.1016/j.bbagen.2010.07.005  0.364
2010 Kuhnert F, Mancuso MR, Shamloo A, Wang HT, Choksi V, Florek M, Su H, Fruttiger M, Young WL, Heilshorn SC, Kuo CJ. Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. Science (New York, N.Y.). 330: 985-9. PMID 21071672 DOI: 10.1126/Science.1196554  0.577
2010 Shamloo A, Heilshorn SC. Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients. Lab On a Chip. 10: 3061-8. PMID 20820484 DOI: 10.1039/C005069E  0.599
2010 Sengupta D, Heilshorn SC. Protein-engineered biomaterials: highly tunable tissue engineering scaffolds. Tissue Engineering. Part B, Reviews. 16: 285-93. PMID 20141386 DOI: 10.1089/ten.teb.2009.0591  0.322
2010 Straley KS, Foo CW, Heilshorn SC. Biomaterial design strategies for the treatment of spinal cord injuries. Journal of Neurotrauma. 27: 1-19. PMID 19698073 DOI: 10.1089/neu.2009.0948  0.68
2010 Shamloo A, Manchandia M, Mani M, Nguyen C, Jahn T, Weinberg KI, Heilshorn S. Paradoxical Dose-Dependent Chemoattractive and Chemorepellent Effects of Kit Ligand (KL) In Mast Cells Revealed In Novel Microfluidic Biochambers. Blood. 116: 1496-1496. DOI: 10.1182/Blood.V116.21.1496.1496  0.624
2010 Shamloo A, Heilshorn SC. The interplay between biomechanical and biochemical factors regulates lumen formation and navigation of endothelial cell sprouts Asme 2010 Summer Bioengineering Conference, Sbc 2010. 429-430. DOI: 10.1115/SBC2010-19495  0.587
2010 Shamloo A, Heilshorn SC. Matrix Rigidity Mediates Growth Factor Response during 3D Endothelial Cell Sprouting Biophysical Journal. 98: 730a. DOI: 10.1016/J.Bpj.2009.12.4000  0.637
2010 Shamloo A, Kuhnert F, Choksi V, Kuo C, Heilshorn S. Novel Receptor-Mediated Endothelial Cell Chemotaxis Biophysical Journal. 98: 497a. DOI: 10.1016/J.Bpj.2009.12.2705  0.64
2009 Wong Po Foo CT, Lee JS, Mulyasasmita W, Parisi-Amon A, Heilshorn SC. Two-component protein-engineered physical hydrogels for cell encapsulation. Proceedings of the National Academy of Sciences of the United States of America. 106: 22067-72. PMID 20007785 DOI: 10.1073/pnas.0904851106  0.314
2009 Straley K, Heilshorn SC. Designer protein-based scaffolds for neural tissue engineering. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 2101-2. PMID 19964779 DOI: 10.1109/IEMBS.2009.5334310  0.753
2009 Straley KS, Heilshorn SC. Design and adsorption of modular engineered proteins to prepare customized, neuron-compatible coatings. Frontiers in Neuroengineering. 2: 9. PMID 19562090 DOI: 10.3389/neuro.16.009.2009  0.723
2009 Wang S, Wong Po Foo C, Warrier A, Poo MM, Heilshorn SC, Zhang X. Gradient lithography of engineered proteins to fabricate 2D and 3D cell culture microenvironments. Biomedical Microdevices. 11: 1127-34. PMID 19495986 DOI: 10.1007/S10544-009-9329-1  0.363
2009 Straley KS, Heilshorn SC. Independent tuning of multiple biomaterial properties using protein engineering Soft Matter. 5: 114-124. DOI: 10.1039/b808504h  0.702
2009 Straley KS, Heilshorn SC. Enzyme-Responsive Hydrogels: Dynamic, 3D-Pattern Formation Within Enzyme-Responsive Hydrogels (Adv. Mater. 41/2009) Advanced Materials. 21: NA-NA. DOI: 10.1002/ADMA.200990152  0.651
2008 Shamloo A, Ma N, Poo MM, Sohn LL, Heilshorn SC. Endothelial cell polarization and chemotaxis in a microfluidic device. Lab On a Chip. 8: 1292-9. PMID 18651071 DOI: 10.1039/B719788H  0.586
2008 Straley K, Foo CWP, Heilshorn S. Cell-adaptable protein scaffolds for spinal cord nerve regeneration Materials Research Society Symposium Proceedings. 1062: 17-22. DOI: 10.1557/Proc-1062-Nn03-05  0.7
2008 Wong Po Foo CT, Heilshorn S. Protein-based hydrogels for cell transplantation under constant physiological conditions Materials Research Society Symposium Proceedings. 1060: 13-20. DOI: 10.1557/Proc-1060-Ll09-04  0.412
2007 Carrico IS, Maskarinec SA, Heilshorn SC, Mock ML, Liu JC, Nowatzki PJ, Franck C, Ravichandran G, Tirrell DA. Lithographic patterning of photoreactive cell-adhesive proteins. Journal of the American Chemical Society. 129: 4874-5. PMID 17397163 DOI: 10.1021/Ja070200B  0.73
2005 Heilshorn SC, Liu JC, Tirrell DA. Cell-binding domain context affects cell behavior on engineered proteins. Biomacromolecules. 6: 318-23. PMID 15638535 DOI: 10.1021/Bm049627Q  0.715
2004 Liu JC, Heilshorn SC, Tirrell DA. Comparative cell response to artificial extracellular matrix proteins containing the RGD and CS5 cell-binding domains. Biomacromolecules. 5: 497-504. PMID 15003012 DOI: 10.1021/Bm034340Z  0.706
2004 Liu JC, Heilshorn SC, Tirrell DA. Endothelial cell response to artificial extracellular matrix proteins Aiche Annual Meeting, Conference Proceedings. 1269.  0.608
2003 Heilshorn SC, DiZio KA, Welsh ER, Tirrell DA. Endothelial cell adhesion to the fibronectin CS5 domain in artificial extracellular matrix proteins. Biomaterials. 24: 4245-52. PMID 12853256 DOI: 10.1016/S0142-9612(03)00294-1  0.58
2002 Liu JC, Heilshorn SC, Tirrell DA. Characterization of endothelial cell response to artificial extracellular matrix proteins containing the RGD cell-binding domain Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 104.  0.581
2002 Heilshorn SC, DiZio KA, Tirrell DA. Endothelial cell interactions with artificial extracellular matrix proteins Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 93.  0.601
2002 Nowatzki P, Heilshorn SC, Liu JC, Di Zio KA, Tirrell DA. Progress toward artificial extracellular matrix protein-based vascular grafts Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 7.  0.668
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