David A. Tirrell - Publications

Affiliations: 
1978-1984 Chemistry Carnegie Mellon University, Pittsburgh, PA 
 1984-1998 University of Massachusetts, Amherst, Amherst, MA 
 1998- California Institute of Technology, Pasadena, CA 
Area:
artificial proteins
Website:
http://chche.divisions.caltech.edu/people/david-a-tirrell

214 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Rapp PB, Omar AK, Silverman BR, Wang ZG, Tirrell DA. Mechanisms of diffusion in associative polymer networks: evidence for chain hopping. Journal of the American Chemical Society. PMID 30272969 DOI: 10.1021/jacs.8b07908  0.72
2018 Fang KY, Lieblich SA, Tirrell DA. Incorporation of Non-Canonical Amino Acids into Proteins by Global Reassignment of Sense Codons. Methods in Molecular Biology (Clifton, N.J.). 1798: 173-186. PMID 29868959 DOI: 10.1007/978-1-4939-7893-9_13  1
2018 Ghazalli N, Wu X, Walker S, Trieu N, Hsin LY, Choe J, Chen C, Hsu J, LeBon J, Kozlowski MT, Rawson J, Tirrell DA, Yip MLR, Ku HT. Glucocorticoid signaling enhances expression of glucose-sensing molecules in immature pancreatic beta-like cells derived from murine embryonic stem cells in vitro. Stem Cells and Development. PMID 29717618 DOI: 10.1089/scd.2017.0160  0.32
2017 Alvarez-Castelao B, Schanzenbächer CT, Hanus C, Glock C, Tom Dieck S, Dörrbaum AR, Bartnik I, Nassim-Assir B, Ciirdaeva E, Mueller A, Dieterich DC, Tirrell DA, Langer JD, Schuman EM. Cell-type-specific metabolic labeling of nascent proteomes in vivo. Nature Biotechnology. PMID 29106408 DOI: 10.1038/nbt.4016  0.4
2017 Obana M, Silverman BR, Tirrell DA. Protein-Mediated Colloidal Assembly. Journal of the American Chemical Society. PMID 28898068 DOI: 10.1021/jacs.7b07798  0.72
2017 Lieblich S, Fang K, Cahn JKB, Rawson J, LeBon J, Ku HT, Tirrell DA. 4S-Hydroxylation of insulin at ProB28 accelerates hexamer dissociation and delays fibrillation. Journal of the American Chemical Society. PMID 28598606 DOI: 10.1021/jacs.7b00794  0.32
2017 Rapp PB, Omar AK, Shen JJ, Buck ME, Wang ZG, Tirrell DA. Analysis and control of chain mobility in protein hydrogels. Journal of the American Chemical Society. PMID 28225256 DOI: 10.1021/jacs.6b13146  0.92
2016 Dooling LJ, Tirrell DA. Engineering the Dynamic Properties of Protein Networks through Sequence Variation. Acs Central Science. 2: 812-819. PMID 27924309 DOI: 10.1021/acscentsci.6b00205  0.4
2016 Tremblay JR, LeBon JM, Luo A, Quijano JC, Wedeken L, Jou K, Riggs AD, Tirrell DA, Ku HT. In Vitro Colony Assays for Characterizing Tri-potent Progenitor Cells Isolated from the Adult Murine Pancreas. Journal of Visualized Experiments : Jove. PMID 27340914 DOI: 10.3791/54016  1
2016 Bertozzi CR, Chang CJ, Davis BG, Olvera de la Cruz M, Tirrell DA, Zhao D. Grand Challenges in Chemistry for 2016 and Beyond. Acs Central Science. 2: 1-3. PMID 27163017 DOI: 10.1021/acscentsci.6b00010  0.4
2016 Dooling LJ, Buck ME, Zhang WB, Tirrell DA. Programming Molecular Association and Viscoelastic Behavior in Protein Networks. Advanced Materials (Deerfield Beach, Fla.). PMID 27061171 DOI: 10.1002/adma.201506216  1
2016 Mahdavi A, Hamblin GD, Jindal GA, Bagert JD, Dong C, Sweredoski MJ, Hess S, Schuman EM, Tirrell DA. An engineered aminoacyl-tRNA synthetase for cell-selective analysis of mammalian protein synthesis. Journal of the American Chemical Society. PMID 26991063 DOI: 10.1021/jacs.5b08980  1
2016 Bagert JD, van Kessel JC, Sweredoski MJ, Feng L, Hess S, Bassler BL, Tirrell DA. Time-resolved proteomic analysis of quorum sensing in Vibrio harveyi. Chemical Science (Royal Society of Chemistry : 2010). 7: 1797-1806. PMID 26925210 DOI: 10.1039/C5SC03340C  1
2016 Babin BM, Bergkessel M, Sweredoski MJ, Moradian A, Hess S, Newman DK, Tirrell DA. SutA is a bacterial transcription factor expressed during slow growth in Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787849 DOI: 10.1073/pnas.1514412113  1
2015 Jin L, Gao D, Feng T, Tremblay JR, Ghazalli N, Luo A, Rawson J, Quijano JC, Chai J, Wedeken L, Hsu J, LeBon J, Walker S, Shih HP, Mahdavi A, ... Tirrell DA, et al. Cells with surface expression of CD133(high)CD71(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. Stem Cell Research. 16: 40-53. PMID 26691820 DOI: 10.1016/j.scr.2015.11.015  0.4
2015 Kulkarni C, Lo M, Fraseur JG, Tirrell DA, Kinzer-Ursem TL. Bioorthogonal Chemoenzymatic Functionalization of Calmodulin for Bioconjugation Applications. Bioconjugate Chemistry. PMID 26431265 DOI: 10.1021/acs.bioconjchem.5b00449  1
2015 Zehner NA, Dietrick SM, Tirrell DA, Kennedy SB. Two-Site Internally Cooperative Mechanism for Enzyme Kinetics in a Hydrogel Forming Recombinant Protein. Biomacromolecules. PMID 26402311 DOI: 10.1021/acs.biomac.5b01110  1
2015 Notbohm J, Lesman A, Rosakis P, Tirrell DA, Ravichandran G. Microbuckling of fibrin provides a mechanism for cell mechanosensing. Journal of the Royal Society, Interface / the Royal Society. 12. PMID 26040601 DOI: 10.1098/rsif.2015.0320  1
2015 Notbohm J, Lesman A, Tirrell DA, Ravichandran G. Quantifying cell-induced matrix deformation in three dimensions based on imaging matrix fibers. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 26021600 DOI: 10.1039/c5ib00013k  1
2015 Ghazalli N, Mahdavi A, Feng T, Jin L, Kozlowski MT, Hsu J, Riggs AD, Tirrell DA, Ku HT. Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro. Stem Cells and Development. PMID 25941840 DOI: 10.1089/scd.2015.0007  1
2015 tom Dieck S, Kochen L, Hanus C, Heumüller M, Bartnik I, Nassim-Assir B, Merk K, Mosler T, Garg S, Bunse S, Tirrell DA, Schuman EM. Direct visualization of newly synthesized target proteins in situ. Nature Methods. 12: 411-4. PMID 25775042 DOI: 10.1038/nmeth.3319  1
2015 DeForest CA, Tirrell DA. A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels. Nature Materials. 14: 523-31. PMID 25707020 DOI: 10.1038/nmat4219  1
2015 Yuet KP, Doma MK, Ngo JT, Sweredoski MJ, Graham RL, Moradian A, Hess S, Schuman EM, Sternberg PW, Tirrell DA. Cell-specific proteomic analysis in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 112: 2705-10. PMID 25691744 DOI: 10.1073/pnas.1421567112  0.48
2015 Feng L, Rutherford ST, Papenfort K, Bagert JD, van Kessel JC, Tirrell DA, Wingreen NS, Bassler BL. A qrr noncoding RNA deploys four different regulatory mechanisms to optimize quorum-sensing dynamics. Cell. 160: 228-40. PMID 25579683 DOI: 10.1016/j.cell.2014.11.051  1
2014 Jin L, Feng T, Chai J, Ghazalli N, Gao D, Zerda R, Li Z, Hsu J, Mahdavi A, Tirrell DA, Riggs AD, Ku HT. Colony-forming progenitor cells in the postnatal mouse liver and pancreas give rise to morphologically distinct insulin-expressing colonies in 3D cultures. The Review of Diabetic Studies : Rds. 11: 35-50. PMID 25148366 DOI: 10.1900/RDS.2014.11.35  1
2014 Sun F, Zhang WB, Mahdavi A, Arnold FH, Tirrell DA. Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry. Proceedings of the National Academy of Sciences of the United States of America. 111: 11269-74. PMID 25049400 DOI: 10.1073/pnas.1401291111  1
2014 Van Deventer JA, Yuet KP, Yoo TH, Tirrell DA. Cell surface display yields evolvable, clickable antibody fragments. Chembiochem : a European Journal of Chemical Biology. 15: 1777-81. PMID 25045032 DOI: 10.1002/cbic.201402184  1
2014 Lesman A, Notbohm J, Tirrell DA, Ravichandran G. Contractile forces regulate cell division in three-dimensional environments. The Journal of Cell Biology. 205: 155-62. PMID 24778310 DOI: 10.1083/jcb.201309029  1
2014 Hatzenpichler R, Scheller S, Tavormina PL, Babin BM, Tirrell DA, Orphan VJ. In situ visualization of newly synthesized proteins in environmental microbes using amino acid tagging and click chemistry. Environmental Microbiology. 16: 2568-90. PMID 24571640 DOI: 10.1111/1462-2920.12436  1
2014 Bagert JD, Xie YJ, Sweredoski MJ, Qi Y, Hess S, Schuman EM, Tirrell DA. Quantitative, time-resolved proteomic analysis by combining bioorthogonal noncanonical amino acid tagging and pulsed stable isotope labeling by amino acids in cell culture. Molecular & Cellular Proteomics : McP. 13: 1352-8. PMID 24563536 DOI: 10.1074/mcp.M113.031914  1
2014 Mahdavi A, Szychowski J, Ngo JT, Sweredoski MJ, Graham RL, Hess S, Schneewind O, Mazmanian SK, Tirrell DA. Identification of secreted bacterial proteins by noncanonical amino acid tagging. Proceedings of the National Academy of Sciences of the United States of America. 111: 433-8. PMID 24347637 DOI: 10.1073/pnas.1301740111  1
2014 Lu YY, Sweredoski MJ, Huss D, Lansford R, Hess S, Tirrell DA. Prometastatic GPCR CD97 is a direct target of tumor suppressor microRNA-126. Acs Chemical Biology. 9: 334-8. PMID 24274104 DOI: 10.1021/cb400704n  1
2014 Burts AO, Liao L, Lu YY, Tirrell DA, Johnson JA. Brush-first and click: efficient synthesis of nanoparticles that degrade and release doxorubicin in response to light. Photochemistry and Photobiology. 90: 380-5. PMID 24117423 DOI: 10.1111/php.12182  1
2014 Yuet KP, Tirrell DA. Chemical tools for temporally and spatially resolved mass spectrometry-based proteomics. Annals of Biomedical Engineering. 42: 299-311. PMID 23943069 DOI: 10.1007/s10439-013-0878-3  1
2014 Wang H, Mahdavi A, Park J, Chi T, Butts J, Hookway TA, McDevitt T, Tirrell DA, Hajimiri A. Cell culture and cell based sensor on CMOS Ieee 2014 Biomedical Circuits and Systems Conference, Biocas 2014 - Proceedings. 468-471. DOI: 10.1109/BioCAS.2014.6981764  1
2014 Babin BM, Bergkessel M, Newman DK, Tirrell DA. Selective proteomics in bacterial dormancy: Enrichment of proteins synthesized by pseudomonas aeruginosa reveals a novel regulator Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area At the 2014 Aiche Annual Meeting. 1: 116.  1
2013 Kulkarni C, Kinzer-Ursem TL, Tirrell DA. Selective functionalization of the protein N terminus with N-myristoyl transferase for bioconjugation in cell lysate. Chembiochem : a European Journal of Chemical Biology. 14: 1958-62. PMID 24030852 DOI: 10.1002/cbic.201300453  1
2013 Zhang WB, Sun F, Tirrell DA, Arnold FH. Controlling macromolecular topology with genetically encoded SpyTag-SpyCatcher chemistry. Journal of the American Chemical Society. 135: 13988-97. PMID 23964715 DOI: 10.1021/ja4076452  1
2013 Le DH, Hanamura R, Pham DH, Kato M, Tirrell DA, Okubo T, Sugawara-Narutaki A. Self-assembly of elastin-mimetic double hydrophobic polypeptides. Biomacromolecules. 14: 1028-34. PMID 23495825 DOI: 10.1021/bm301887m  1
2013 Ngo JT, Schuman EM, Tirrell DA. Mutant methionyl-tRNA synthetase from bacteria enables site-selective N-terminal labeling of proteins expressed in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 4992-7. PMID 23479642 DOI: 10.1073/pnas.1216375110  1
2013 Jin L, Feng T, Shih HP, Zerda R, Luo A, Hsu J, Mahdavi A, Sander M, Tirrell DA, Riggs AD, Ku HT. Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. Proceedings of the National Academy of Sciences of the United States of America. 110: 3907-12. PMID 23431132 DOI: 10.1073/pnas.1301889110  1
2013 Mahdavi A, Segall-Shapiro TH, Kou S, Jindal GA, Hoff KG, Liu S, Chitsaz M, Ismagilov RF, Silberg JJ, Tirrell DA. A genetically encoded and gate for cell-targeted metabolic labeling of proteins. Journal of the American Chemical Society. 135: 2979-82. PMID 23406315 DOI: 10.1021/ja400448f  0.4
2013 Tzlil S, Tirrell DA. Strain propagation in artificial extracellular matrix proteins can accelerate cell spreading and polarization Soft Matter. 9: 5602-5608. DOI: 10.1039/c3sm27137d  1
2013 Tirrell DA. The wonder of life in its chemical aspect Advances in Polymer Science. 261: 199-210. DOI: 10.1007/12-2013-261  1
2013 Kulkarni C, Tirrell DA, Kinzer-Ursem TL. Chemoenzymatic labeling of recombinant proteins enables rapid in-lysate bioconjugation and assay development Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 265.  1
2012 Wang H, Mahdavi A, Tirrell DA, Hajimiri A. A magnetic cell-based sensor. Lab On a Chip. 12: 4465-71. PMID 22976747 DOI: 10.1039/c2lc40392g  1
2012 Patel PR, Kiser RC, Lu YY, Fong E, Ho WC, Tirrell DA, Grubbs RH. Synthesis and cell adhesive properties of linear and cyclic RGD functionalized polynorbornene thin films. Biomacromolecules. 13: 2546-53. PMID 22783892 DOI: 10.1021/bm300795y  1
2012 Hodas JJ, Nehring A, Höche N, Sweredoski MJ, Pielot R, Hess S, Tirrell DA, Dieterich DC, Schuman EM. Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT). Proteomics. 12: 2464-76. PMID 22744909 DOI: 10.1002/pmic.201200112  1
2012 Ngo JT, Babin BM, Champion JA, Schuman EM, Tirrell DA. State-selective metabolic labeling of cellular proteins. Acs Chemical Biology. 7: 1326-30. PMID 22692961 DOI: 10.1021/cb300238w  1
2012 Truong F, Yoo TH, Lampo TJ, Tirrell DA. Two-strain, cell-selective protein labeling in mixed bacterial cultures. Journal of the American Chemical Society. 134: 8551-6. PMID 22575034 DOI: 10.1021/ja3004667  1
2012 Hinz FI, Dieterich DC, Tirrell DA, Schuman EM. Non-canonical amino acid labeling in vivo to visualize and affinity purify newly synthesized proteins in larval zebrafish. Acs Chemical Neuroscience. 3: 40-49. PMID 22347535 DOI: 10.1021/cn2000876  1
2012 Notbohm J, Kim JH, Franck C, Maskarinec S, Tirrell D, Asthagiri A, Ravichandran G. Three-dimensional traction force microscopy for studying cellular interactions with biomaterials Procedia Iutam. 4: 144-150. DOI: 10.1016/j.piutam.2012.05.016  1
2012 Buck ME, Tirrell DA. Artificial Proteins Polymer Science: a Comprehensive Reference, 10 Volume Set. 9: 117-136. DOI: 10.1016/B978-0-444-53349-4.00219-3  1
2012 Langer RS, Tirrell DA. Introduction and Overview Polymer Science: a Comprehensive Reference, 10 Volume Set. 9: 1-2. DOI: 10.1016/B978-0-444-53349-4.00218-1  1
2011 Xia Y, Li Y, Burts AO, Ottaviani MF, Tirrell DA, Johnson JA, Turro NJ, Grubbs RH. EPR study of spin labeled brush polymers in organic solvents. Journal of the American Chemical Society. 133: 19953-9. PMID 22023139 DOI: 10.1021/ja2085349  1
2011 Beatty KE, Szychowski J, Fisk JD, Tirrell DA. A BODIPY-cyclooctyne for protein imaging in live cells. Chembiochem : a European Journal of Chemical Biology. 12: 2137-9. PMID 21830285 DOI: 10.1002/cbic.201100277  1
2011 Ngo JT, Tirrell DA. Noncanonical amino acids in the interrogation of cellular protein synthesis. Accounts of Chemical Research. 44: 677-85. PMID 21815659 DOI: 10.1021/ar200144y  1
2011 Franck C, Maskarinec SA, Tirrell DA, Ravichandran G. Three-dimensional traction force microscopy: a new tool for quantifying cell-matrix interactions. Plos One. 6: e17833. PMID 21468318 DOI: 10.1371/journal.pone.0017833  1
2011 Van Deventer JA, Fisk JD, Tirrell DA. Homoisoleucine: a translationally active leucine surrogate of expanded hydrophobic surface area. Chembiochem : a European Journal of Chemical Biology. 12: 700-2. PMID 21404412 DOI: 10.1002/cbic.201000731  1
2011 Reichert WM, Ratner BD, Anderson J, Coury A, Hoffman AS, Laurencin CT, Tirrell D. 2010 Panel on the biomaterials grand challenges. Journal of Biomedical Materials Research. Part A. 96: 275-87. PMID 21171147 DOI: 10.1002/jbm.a.32969  1
2011 Johnson JA, Lu YY, Burts AO, Lim YH, Finn MG, Koberstein JT, Turro NJ, Tirrell DA, Grubbs RH. Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to. Journal of the American Chemical Society. 133: 559-66. PMID 21142161 DOI: 10.1021/ja108441d  1
2010 Johnson JA, Lu YY, Burts AO, Xia Y, Durrell AC, Tirrell DA, Grubbs RH. Drug-loaded, bivalent-bottle-brush polymers by graft-through ROMP. Macromolecules. 43: 10326-10335. PMID 21532937 DOI: 10.1021/ma1021506  1
2010 Olsen BD, Kornfield JA, Tirrell DA. Yielding Behavior in Injectable Hydrogels from Telechelic Proteins. Macromolecules. 43: 9094-9099. PMID 21221427 DOI: 10.1021/ma101434a  1
2010 Szychowski J, Mahdavi A, Hodas JJ, Bagert JD, Ngo JT, Landgraf P, Dieterich DC, Schuman EM, Tirrell DA. Cleavable biotin probes for labeling of biomolecules via azide-alkyne cycloaddition. Journal of the American Chemical Society. 132: 18351-60. PMID 21141861 DOI: 10.1021/ja1083909  1
2010 Johnson JA, Lu YY, Van Deventer JA, Tirrell DA. Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications. Current Opinion in Chemical Biology. 14: 774-80. PMID 21071259 DOI: 10.1016/j.cbpa.2010.09.013  1
2010 Fong E, Tzlil S, Tirrell DA. Boundary crossing in epithelial wound healing. Proceedings of the National Academy of Sciences of the United States of America. 107: 19302-7. PMID 20974917 DOI: 10.1073/pnas.1008291107  1
2010 Fong E, Tirrell DA. Collective cell migration on artificial extracellular matrix proteins containing full-length fibronectin domains. Advanced Materials (Deerfield Beach, Fla.). 22: 5271-5. PMID 20886461 DOI: 10.1002/adma.201002448  1
2010 Kwon OH, Yoo TH, Othon CM, Van Deventer JA, Tirrell DA, Zewail AH. Hydration dynamics at fluorinated protein surfaces. Proceedings of the National Academy of Sciences of the United States of America. 107: 17101-6. PMID 20855583 DOI: 10.1073/pnas.1011569107  1
2010 Beatty KE, Fisk JD, Smart BP, Lu YY, Szychowski J, Hangauer MJ, Baskin JM, Bertozzi CR, Tirrell DA. Live-cell imaging of cellular proteins by a strain-promoted azide-alkyne cycloaddition. Chembiochem : a European Journal of Chemical Biology. 11: 2092-5. PMID 20836119 DOI: 10.1002/cbic.201000419  1
2010 Dieterich DC, Hodas JJ, Gouzer G, Shadrin IY, Ngo JT, Triller A, Tirrell DA, Schuman EM. In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nature Neuroscience. 13: 897-905. PMID 20543841 DOI: 10.1038/nn.2580  1
2009 Maskarinec SA, Franck C, Tirrell DA, Ravichandran G. Quantifying cellular traction forces in three dimensions. Proceedings of the National Academy of Sciences of the United States of America. 106: 22108-13. PMID 20018765 DOI: 10.1073/pnas.0904565106  1
2009 Schmitt E, Tanrikulu IC, Yoo TH, Panvert M, Tirrell DA, Mechulam Y. Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. Journal of Molecular Biology. 394: 843-51. PMID 19837083 DOI: 10.1016/j.jmb.2009.10.016  1
2009 Zhang K, Sugawara A, Tirrell DA. Generation of surface-bound multicomponent protein gradients. Chembiochem : a European Journal of Chemical Biology. 10: 2617-9. PMID 19780079 DOI: 10.1002/cbic.200900542  1
2009 Tanrikulu IC, Schmitt E, Mechulam Y, Goddard WA, Tirrell DA. Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 15285-90. PMID 19706454 DOI: 10.1073/pnas.0905735106  1
2009 Tang Y, Wang P, Van Deventer JA, Link AJ, Tirrell DA. Introduction of an aliphatic ketone into recombinant proteins in a bacterial strain that overexpresses an editing-impaired leucyl-tRNA synthetase. Chembiochem : a European Journal of Chemical Biology. 10: 2188-90. PMID 19670197 DOI: 10.1002/cbic.200900407  1
2009 Ngo JT, Champion JA, Mahdavi A, Tanrikulu IC, Beatty KE, Connor RE, Yoo TH, Dieterich DC, Schuman EM, Tirrell DA. Cell-selective metabolic labeling of proteins. Nature Chemical Biology. 5: 715-7. PMID 19668194 DOI: 10.1038/nchembio.200  1
2009 Montclare JK, Son S, Clark GA, Kumar K, Tirrell DA. Biosynthesis and stability of coiled-coil peptides containing (2S,4R)-5,5,5-trifluoroleucine and (2S,4S)-5,5,5-trifluoroleucine. Chembiochem : a European Journal of Chemical Biology. 10: 84-6. PMID 19090517 DOI: 10.1002/cbic.200800164  1
2008 Liu JC, Tirrell DA. Cell response to RGD density in cross-linked artificial extracellular matrix protein films. Biomacromolecules. 9: 2984-8. PMID 18826275 DOI: 10.1021/bm800469j  1
2008 Beatty KE, Tirrell DA. Two-color labeling of temporally defined protein populations in mammalian cells. Bioorganic & Medicinal Chemistry Letters. 18: 5995-9. PMID 18774715 DOI: 10.1016/j.bmcl.2008.08.046  1
2008 Strable E, Prasuhn DE, Udit AK, Brown S, Link AJ, Ngo JT, Lander G, Quispe J, Potter CS, Carragher B, Tirrell DA, Finn MG. Unnatural amino acid incorporation into virus-like particles. Bioconjugate Chemistry. 19: 866-75. PMID 18318461 DOI: 10.1021/bc700390r  1
2008 Connor RE, Piatkov K, Varshavsky A, Tirrell DA. Enzymatic N-terminal addition of noncanonical amino acids to peptides and proteins. Chembiochem : a European Journal of Chemical Biology. 9: 366-9. PMID 18203209 DOI: 10.1002/cbic.200700605  1
2008 Wang A, Winblade Nairn N, Johnson RS, Tirrell DA, Grabstein K. Processing of N-terminal unnatural amino acids in recombinant human interferon-beta in Escherichia coli. Chembiochem : a European Journal of Chemical Biology. 9: 324-30. PMID 18098265 DOI: 10.1002/cbic.200700379  1
2008 Nowatzki PJ, Franck C, Maskarinec SA, Ravichandran G, Tirrell DA. Mechanically tunable thin films of photosensitive artificial proteins: Preparation and characterization by nanoindentation Macromolecules. 41: 1839-1845. DOI: 10.1021/ma071717a  1
2008 Kiick KL, Tirrell DA. Biosynthetic Routes to Novel Macromolecular Materials Materials Science and Technology: a Comprehensive Treatment. 571-594. DOI: 10.1002/9783527619313.ch17  1
2008 Van Deventer JA, Yoo TH, Tirrell DA. Affinity maturation of antibody fragments containing non-canonical amino acids Aiche Annual Meeting, Conference Proceedings 1
2008 Liu JC, Tirrell DA. Modulating endothelial cell response to crosslinked artificial extracellular matrix proteins Aiche Annual Meeting, Conference Proceedings 1
2008 Tirrell DA. Protein modification through click chemistry American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 49: 199.  1
2007 Yoo TH, Link AJ, Tirrell DA. Evolution of a fluorinated green fluorescent protein. Proceedings of the National Academy of Sciences of the United States of America. 104: 13887-90. PMID 17717085 DOI: 10.1073/pnas.0701904104  1
2007 Link AJ, Vink MK, Tirrell DA. Synthesis of the functionalizable methionine surrogate azidohomoalanine using Boc-homoserine as precursor. Nature Protocols. 2: 1884-7. PMID 17703199 DOI: 10.1038/nprot.2007.269  1
2007 Link AJ, Vink MK, Tirrell DA. Preparation of the functionalizable methionine surrogate azidohomoalanine via copper-catalyzed diazo transfer. Nature Protocols. 2: 1879-83. PMID 17703198 DOI: 10.1038/nprot.2007.268  1
2007 Kwon I, Tirrell DA. Site-specific incorporation of tryptophan analogues into recombinant proteins in bacterial cells. Journal of the American Chemical Society. 129: 10431-7. PMID 17685515 DOI: 10.1021/ja071773r  1
2007 Yoo TH, Tirrell DA. High-throughput screening for methionyl-tRNA synthetases that enable residue-specific incorporation of noncanonical amino acids into recombinant proteins in bacterial cells. Angewandte Chemie (International Ed. in English). 46: 5340-3. PMID 17568466 DOI: 10.1002/anie.200700779  1
2007 Dieterich DC, Lee JJ, Link AJ, Graumann J, Tirrell DA, Schuman EM. Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging. Nature Protocols. 2: 532-40. PMID 17406607 DOI: 10.1038/nprot.2007.52  1
2007 Carrico IS, Maskarinec SA, Heilshorn SC, Mock ML, Liu JC, Nowatzki PJ, Franck C, Ravichandran G, Tirrell DA. Lithographic patterning of photoreactive cell-adhesive proteins. Journal of the American Chemical Society. 129: 4874-5. PMID 17397163 DOI: 10.1021/ja070200b  1
2007 Connor RE, Tirrell DA. Non-canonical amino acids in protein polymer design Polymer Reviews. 47: 9-28. DOI: 10.1080/15583720601109552  1
2007 Shen W, Kornfield JA, Tirrell DA. Structure and mechanical properties of artificial protein hydrogels assembled through aggregation of leucine zipper peptide domains Soft Matter. 3: 99-107. DOI: 10.1039/b610986a  1
2007 Shen W, Kornfield JA, Tirrell DA. Dynamic properties of artificial protein hydrogels assembled through aggregation of leucine zipper peptide domains Macromolecules. 40: 689-692. DOI: 10.1021/ma0615194  1
2007 Franck C, Hong S, Maskarinec SA, Tirrell DA, Ravichandran G. Three-dimensional full-field measurements of large deformations in soft materials using confocal microscopy and digital volume correlation Experimental Mechanics. 47: 427-438. DOI: 10.1007/s11340-007-9037-9  1
2006 Beatty KE, Liu JC, Xie F, Dieterich DC, Schuman EM, Wang Q, Tirrell DA. Fluorescence visualization of newly synthesized proteins in mammalian cells. Angewandte Chemie (International Ed. in English). 45: 7364-7. PMID 17036290 DOI: 10.1002/anie.200602114  1
2006 Kwon I, Wang P, Tirrell DA. Design of a bacterial host for site-specific incorporation of p-bromophenylalanine into recombinant proteins. Journal of the American Chemical Society. 128: 11778-83. PMID 16953616 DOI: 10.1021/ja0626281  1
2006 Link AJ, Vink MK, Agard NJ, Prescher JA, Bertozzi CR, Tirrell DA. Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proceedings of the National Academy of Sciences of the United States of America. 103: 10180-5. PMID 16801548 DOI: 10.1073/pnas.0601167103  1
2006 Dieterich DC, Link AJ, Graumann J, Tirrell DA, Schuman EM. Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proceedings of the National Academy of Sciences of the United States of America. 103: 9482-7. PMID 16769897 DOI: 10.1073/pnas.0601637103  1
2006 Montclare JK, Tirrell DA. Evolving proteins of novel composition. Angewandte Chemie (International Ed. in English). 45: 4518-21. PMID 16763955 DOI: 10.1002/anie.200600088  1
2006 Son S, Tanrikulu IC, Tirrell DA. Stabilization of bzip peptides through incorporation of fluorinated aliphatic residues. Chembiochem : a European Journal of Chemical Biology. 7: 1251-7. PMID 16758500 DOI: 10.1002/cbic.200500420  1
2006 Diehl MR, Zhang K, Lee HJ, Tirrell DA. Engineering cooperativity in biomotor-protein assemblies. Science (New York, N.Y.). 311: 1468-71. PMID 16527982 DOI: 10.1126/science.1122125  1
2006 Shen W, Zhang K, Kornfield JA, Tirrell DA. Tuning the erosion rate of artificial protein hydrogels through control of network topology. Nature Materials. 5: 153-8. PMID 16444261 DOI: 10.1038/nmat1573  1
2006 Mock ML, Michon T, van Hest JC, Tirrell DA. Stereoselective incorporation of an unsaturated isoleucine analogue into a protein expressed in E. coli. Chembiochem : a European Journal of Chemical Biology. 7: 83-7. PMID 16397872 DOI: 10.1002/cbic.200500201  1
2006 Ishikawa T, Takasu A, Tirrell DA. In vivo incorporation of phenylalanine derivatives into proteins Polymer Preprints, Japan. 55: 4818.  1
2006 Franck C, Nowatzki PJ, Ravichandran G, Tirrell DA. Nanoindentation and finite element modeling of extracellular matrix proteins Proceedings of the 2006 Sem Annual Conference and Exposition On Experimental and Applied Mechanics 2006. 1: 193-194.  1
2005 Beatty KE, Xie F, Wang Q, Tirrell DA. Selective dye-labeling of newly synthesized proteins in bacterial cells. Journal of the American Chemical Society. 127: 14150-1. PMID 16218586 DOI: 10.1021/ja054643w  1
2005 Cantrill SJ, Grubbs RH, Lanari D, Leung KC, Nelson A, Poulin-Kerstien KG, Smidt SP, Stoddart JF, Tirrell DA. Template-directed olefin cross metathesis. Organic Letters. 7: 4213-6. PMID 16146390 DOI: 10.1021/ol051599g  1
2005 Link AJ, Tirrell DA. Reassignment of sense codons in vivo. Methods (San Diego, Calif.). 36: 291-8. PMID 16076455 DOI: 10.1016/j.ymeth.2005.04.005  1
2005 Zhang K, Diehl MR, Tirrell DA. Artificial polypeptide scaffold for protein immobilization. Journal of the American Chemical Society. 127: 10136-7. PMID 16028902 DOI: 10.1021/ja051457h  1
2005 Maskarinec SA, Tirrell DA. Protein engineering approaches to biomaterials design. Current Opinion in Biotechnology. 16: 422-6. PMID 16006115 DOI: 10.1016/j.copbio.2005.06.009  1
2005 Stevens MM, Allen S, Davies MC, Roberts CJ, Sakata JK, Tendler SJ, Tirrell DA, Williams PM. Molecular level investigations of the inter- and intramolecular interactions of pH-responsive artificial triblock proteins. Biomacromolecules. 6: 1266-71. PMID 15877341 DOI: 10.1021/bm049369x  1
2005 Smeenk JM, Otten MB, Thies J, Tirrell DA, Stunnenberg HG, van Hest JC. Controlled assembly of macromolecular beta-sheet fibrils. Angewandte Chemie (International Ed. in English). 44: 1968-71. PMID 15724260 DOI: 10.1002/anie.200462415  1
2005 Heilshorn SC, Liu JC, Tirrell DA. Cell-binding domain context affects cell behavior on engineered proteins. Biomacromolecules. 6: 318-23. PMID 15638535 DOI: 10.1021/bm049627q  1
2005 Richman GP, Tirrell DA, Asthagiri AR. Quantitatively distinct requirements for signaling-competent cell spreading on engineered versus natural adhesion ligands. Journal of Controlled Release : Official Journal of the Controlled Release Society. 101: 3-12. PMID 15588889 DOI: 10.1016/j.jconrel.2004.07.034  1
2005 Kennedy SB, Littrell K, Thiyagarajan P, Tirrell DA, Russell TP. Controlled structure in artificial protein hydrogels Macromolecules. 38: 7470-7475. DOI: 10.1021/ma050726l  1
2005 Shen W, Lammertink RGH, Sakata JK, Kornfield JA, Tirrell DA. Assembly of an artificial protein hydrogel through leucine zipper aggregation and bisulfide bond formation Macromolecules. 38: 3909-3916. DOI: 10.1021/ma048348s  1
2005 Kwon I, Tirrell DA. Protein engineering by single or multiple site-specific incorporation of nonnatural amino acids in vivo Aiche Annual Meeting, Conference Proceedings. 3442.  1
2005 Van Deventer JA, Link AJ, Tang Y, Wang P, Tirrell DA. Incorporation and labeling of an aliphatic ketone in recombinant proteins Aiche Annual Meeting, Conference Proceedings. 8700.  1
2005 Son S, Tirrell DA. Laboratory evolution of a fluorinated protein Aiche Annual Meeting, Conference Proceedings. 9280.  1
2005 Galownia N, Davis M, Tirrell D, Asthagiri AR. Quantitative adhesion requirements for intracellular signaling, cell spreading and cell proliferation Aiche Annual Meeting, Conference Proceedings. 5303.  1
2004 Chen T, McIntosh D, He Y, Kim J, Tirrell DA, Scherrer P, Fenske DB, Sandhu AP, Cullis PR. Alkylated derivatives of poly(ethylacrylic acid) can be inserted into preformed liposomes and trigger pH-dependent intracellular delivery of liposomal contents. Molecular Membrane Biology. 21: 385-93. PMID 15764368 DOI: 10.1080/09687860400010516  1
2004 Link AJ, Vink MK, Tirrell DA. Presentation and detection of azide functionality in bacterial cell surface proteins. Journal of the American Chemical Society. 126: 10598-602. PMID 15327317 DOI: 10.1021/ja047629c  1
2004 Stevens MM, Allen S, Sakata JK, Davies MC, Roberts CJ, Tendler SJ, Tirrell DA, Williams PM. pH-dependent behavior of surface-immobilized artificial leucine zipper proteins. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 7747-52. PMID 15323527 DOI: 10.1021/la030440e  1
2004 Tirrell DA. Chemical biology: hitting the sweet spot. Nature. 430: 837. PMID 15318200 DOI: 10.1038/430837a  1
2004 Wang P, Fichera A, Kumar K, Tirrell DA. Alternative translations of a single RNA message: an identity switch of (2S,3R)-4,4,4-trifluorovaline between valine and isoleucine codons. Angewandte Chemie (International Ed. in English). 43: 3664-6. PMID 15248267 DOI: 10.1002/anie.200454036  1
2004 Sneer R, Weygand MJ, Kjaer K, Tirrell DA, Rapaport H. Parallel beta-sheet assemblies at interfaces. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 5: 747-50. PMID 15179733 DOI: 10.1002/cphc.200301046  1
2004 Langer R, Tirrell DA. Designing materials for biology and medicine. Nature. 428: 487-92. PMID 15057821 DOI: 10.1038/nature02388  1
2004 Liu JC, Heilshorn SC, Tirrell DA. Comparative cell response to artificial extracellular matrix proteins containing the RGD and CS5 cell-binding domains. Biomacromolecules. 5: 497-504. PMID 15003012 DOI: 10.1021/bm034340z  1
2004 Nowatzki PJ, Tirrell DA. Physical properties of artificial extracellular matrix protein films prepared by isocyanate crosslinking. Biomaterials. 25: 1261-7. PMID 14643600 DOI: 10.1016/S0142-9612(03)00635-5  1
2004 Tirrell DA. Otto Vogl from '74 to 75 Journal of Polymer Science, Part a: Polymer Chemistry. 42: 389-390. DOI: 10.1002/pola.11086  1
2004 Stevens MM, Flynn NT, Wang C, Tirrell DA, Langer R. Coiled-coil peptide-based assembly of gold nanoparticles Advanced Materials. 16: 915-918. DOI: 10.1002/adma.200306430  1
2004 Liu JC, Heilshorn SC, Tirrell DA. Endothelial cell response to artificial extracellular matrix proteins Aiche Annual Meeting, Conference Proceedings. 1269.  1
2004 Kros A, Linhardt JG, Bowman HK, Tirrell DA. From giant vesicles to filaments and wires: Templates for conducting polymers Advanced Materials. 16: 723-727+668.  1
2003 Link AJ, Tirrell DA. Cell surface labeling of Escherichia coli via copper(I)-catalyzed [3+2] cycloaddition. Journal of the American Chemical Society. 125: 11164-5. PMID 16220915 DOI: 10.1021/ja036765z  1
2003 Liu CY, Westerlund U, Svensson M, Moe MC, Varghese M, Berg-Johnsen J, Apuzzo ML, Tirrell DA, Langmoen IA. Artificial niches for human adult neural stem cells: possibility for autologous transplantation therapy. Journal of Hematotherapy & Stem Cell Research. 12: 689-99. PMID 14977478 DOI: 10.1089/15258160360732713  1
2003 Link AJ, Mock ML, Tirrell DA. Non-canonical amino acids in protein engineering. Current Opinion in Biotechnology. 14: 603-9. PMID 14662389 DOI: 10.1016/j.copbio.2003.10.011  1
2003 Yamaoka T, Tamura T, Seto Y, Tada T, Kunugi S, Tirrell DA. Mechanism for the phase transition of a genetically engineered elastin model peptide (VPGIG)40 in aqueous solution. Biomacromolecules. 4: 1680-5. PMID 14606895 DOI: 10.1021/bm034120l  1
2003 Cirino PC, Tang Y, Takahashi K, Tirrell DA, Arnold FH. Global incorporation of norleucine in place of methionine in cytochrome P450 BM-3 heme domain increases peroxygenase activity. Biotechnology and Bioengineering. 83: 729-34. PMID 12889037 DOI: 10.1002/bit.10718  1
2003 Heilshorn SC, DiZio KA, Welsh ER, Tirrell DA. Endothelial cell adhesion to the fibronectin CS5 domain in artificial extracellular matrix proteins. Biomaterials. 24: 4245-52. PMID 12853256 DOI: 10.1016/S0142-9612(03)00294-1  1
2003 Kwon I, Kirshenbaum K, Tirrell DA. Breaking the degeneracy of the genetic code. Journal of the American Chemical Society. 125: 7512-3. PMID 12812480 DOI: 10.1021/ja0350076  1
2003 Wang P, Tang Y, Tirrell DA. Incorporation of trifluoroisoleucine into proteins in vivo. Journal of the American Chemical Society. 125: 6900-6. PMID 12783542 DOI: 10.1021/ja0298287  1
2003 Liu CY, Apuzzo ML, Tirrell DA. Engineering of the extracellular matrix: working toward neural stem cell programming and neurorestoration--concept and progress report. Neurosurgery. 52: 1154-65; discussion . PMID 12699561  1
2003 Fukuto M, Heilmann RK, Pershan PS, Yu SM, Soto CM, Tirrell DA. Internal segregation and side chain ordering in hairy-rod polypeptide monolayers at the gas/water interface: An x-ray scattering study Journal of Chemical Physics. 119: 6253-6270. DOI: 10.1063/1.1602058  1
2003 Di Zio K, Tirrell DA. Mechanical properties of artificial protein matrices engineered for control of cell and tissue behavior Macromolecules. 36: 1553-1558. DOI: 10.1021/ma0256587  1
2002 Wang P, Vaidehi N, Tirrell DA, Goddard WA. Virtual screening for binding of phenylalanine analogues to phenylalanyl-tRNA synthetase. Journal of the American Chemical Society. 124: 14442-9. PMID 12452720 DOI: 10.1021/ja0175441  1
2002 Fukuto M, Heilmann RK, Pershan PS, Yu SM, Soto CM, Tirrell DA. Confinement-induced order of tethered alkyl chains at the water/vapor interface. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 66: 010601. PMID 12241332 DOI: 10.1103/PhysRevE.66.010601  1
2002 Tang Y, Tirrell DA. Attenuation of the editing activity of the Escherichia coli leucyl-tRNA synthetase allows incorporation of novel amino acids into proteins in vivo. Biochemistry. 41: 10635-45. PMID 12186549 DOI: 10.1021/bi026130x  1
2002 Rapaport H, Möller G, Knobler CM, Jensen TR, Kjaer K, Leiserowitz L, Tirrell DA. Assembly of triple-stranded beta-sheet peptides at interfaces. Journal of the American Chemical Society. 124: 9342-3. PMID 12167007 DOI: 10.1021/ja026765j  1
2002 Datta D, Wang P, Carrico IS, Mayo SL, Tirrell DA. A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins. Journal of the American Chemical Society. 124: 5652-3. PMID 12010034 DOI: 10.1021/ja0177096  1
2002 Kirshenbaum K, Carrico IS, Tirrell DA. Biosynthesis of proteins incorporating a versatile set of phenylalanine analogues. Chembiochem : a European Journal of Chemical Biology. 3: 235-7. PMID 11921403 DOI: 10.1002/1439-7633(20020301)3:2/3<235::AID-CBIC235>3.0.CO;2-7  1
2002 Kiick KL, Saxon E, Tirrell DA, Bertozzi CR. Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proceedings of the National Academy of Sciences of the United States of America. 99: 19-24. PMID 11752401 DOI: 10.1073/pnas.012583299  1
2002 Mawn MV, Fournier MJ, Tirrell DA, Mason TL. Depletion of free 30S ribosomal subunits in Escherichia coli by expression of RNA containing Shine-Dalgarno-like sequences. Journal of Bacteriology. 184: 494-502. PMID 11751827 DOI: 10.1128/JB.184.2.494-502.2002  1
2002 Nowatzki P, Heilshorn SC, Liu JC, Di Zio KA, Tirrell DA. Progress toward artificial extracellular matrix protein-based vascular grafts Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 7.  1
2002 Heilshorn SC, DiZio KA, Tirrell DA. Endothelial cell interactions with artificial extracellular matrix proteins Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 93.  1
2002 Liu JC, Heilshorn SC, Tirrell DA. Characterization of endothelial cell response to artificial extracellular matrix proteins containing the RGD cell-binding domain Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 104.  1
2002 Niemz A, Shahgholi M, Tirrell DA. Liposome-templated specific protein modification quantified by LC-MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 313-314.  1
2001 Tang Y, Ghirlanda G, Petka WA, Nakajima T, DeGrado WF, Tirrell DA. Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability. Angewandte Chemie (International Ed. in English). 40: 1494-1496. PMID 29712367 DOI: 10.1002/1521-3773(20010417)40:8<1494::AID-ANIE1494>3.0.CO;2-X  1
2001 van Hest JC, Tirrell DA. Protein-based materials, toward a new level of structural control. Chemical Communications (Cambridge, England). 1897-904. PMID 12240211 DOI: 10.1039/b105185g  1
2001 Tang Y, Tirrell DA. Biosynthesis of a highly stable coiled-coil protein containing hexafluoroleucine in an engineered bacterial host. Journal of the American Chemical Society. 123: 11089-90. PMID 11686725 DOI: 10.1021/ja016652k  1
2001 Kiick KL, Weberskirch R, Tirrell DA. Identification of an expanded set of translationally active methionine analogues in Escherichia coli. Febs Letters. 502: 25-30. PMID 11478942 DOI: 10.1016/S0014-5793(01)02657-6  1
2001 Niemz A, Tirrell DA. Self-association and membrane-binding behavior of melittins containing trifluoroleucine. Journal of the American Chemical Society. 123: 7407-13. PMID 11472172 DOI: 10.1021/ja004351p  1
2001 Tang Y, Ghirlanda G, Petka WA, Nakajima T, DeGrado WF, Tirrell DA. Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability This work was supported by a grant from the U.S. Army Research Office. Y. Tang is supported by a Whitaker Graduate Research Fellowship. We thank Dr. Gary Hathaway for performing matrix-assisted laser desorption/ionization analyses. Angewandte Chemie (International Ed. in English). 40: 1494-1496. PMID 11317312 DOI: 10.1002/1521-3773(20010417)40:8<1494::AID-ANIE1494>3.0.CO;2-X  1
2001 Tang Y, Ghirlanda G, Vaidehi N, Kua J, Mainz DT, Goddard III WA, DeGrado WF, Tirrell DA. Stabilization of coiled-coil peptide domains by introduction of trifluoroleucine. Biochemistry. 40: 2790-6. PMID 11258889 DOI: 10.1021/bi0022588  1
2001 Kennedy SB, DeAzevedo ER, Petka WA, Russell TP, Tirrell DA, Hong M. Dynamic structure of a protein hydrogel: A solid-state NMR study Macromolecules. 34: 8675-8685. DOI: 10.1021/ma010768j  1
2000 Tamura T, Yamaoka T, Kunugi S, Panitch A, Tirrell DA. Effects of temperature and pressure on the aggregation properties of an engineered elastin model polypeptide in aqueous solution. Biomacromolecules. 1: 552-5. PMID 11710180  1
2000 Yu SM, Tirrell DA. Thermal and structural properties of biologically derived monodisperse hairy-rod polymers. Biomacromolecules. 1: 310-2. PMID 11710117  1
2000 Welsh ER, Tirrell DA. Engineering the extracellular matrix: a novel approach to polymeric biomaterials. I. Control of the physical properties of artificial protein matrices designed to support adhesion of vascular endothelial cells. Biomacromolecules. 1: 23-30. PMID 11709838  1
2000 Kiick KL, van Hest JC, Tirrell DA. Expanding the Scope of Protein Biosynthesis by Altering the Methionyl-tRNA Synthetase Activity of a Bacterial Expression Host Scott Ross was helpful in conducting the 1D TOCSY NMR experiments and Pratip Bhattachary is thanked for assistance in other NMR experiments. We are grateful to Yves Mechulam for a sample of plasmid pBSM547W305F and to Hieronim Jakubowski of UMDNJ-New Jersey Medical School, Newark, New Jersey, for plasmid pGG3. K.L.K. thanks the U.S. Department of Defense for a National Defense Science and Engineering Graduate Fellowship. This work was supported by grants from the Polymers and Genetics Programs of the National Science Foundation and from the U.S. Army Research Office. Angewandte Chemie (International Ed. in English). 39: 2148-2152. PMID 10941044 DOI: 10.1002/1521-3773(20000616)39:12<2148::AID-ANIE2148>3.0.CO;2-7  1
2000 Thomas JL, Tirrell DA. Polymer-induced leakage of cations from dioleoyl phosphatidylcholine and phosphatidylglycerol liposomes Journal of Controlled Release. 67: 203-209. PMID 10825554 DOI: 10.1016/S0168-3659(00)00209-1  1
2000 Sharma N, Furter R, Kast P, Tirrell DA. Efficient introduction of aryl bromide functionality into proteins in vivo. Febs Letters. 467: 37-40. PMID 10664452 DOI: 10.1016/S0014-5793(00)01120-0  1
2000 Linhardt JG, Tirrell DA. pH-induced fusion and lysis of phosphatidylcholine vesicles by the hydrophobic polyelectrolyte poly(2-ethylacrylic acid) Langmuir. 16: 122-127. DOI: 10.1021/la9906267  1
2000 Van Hest JCM, Kiick KL, Tirrell DA. Efficient incorporation of unsaturated methionine analogues into proteins in vivo Journal of the American Chemical Society. 122: 1282-1288. DOI: 10.1021/ja992749j  1
2000 Rapaport H, Kjaer K, Jensen TR, Leiserowitz L, Tirrell DA. Two-dimensional order in β-sheet peptide monolayers Journal of the American Chemical Society. 122: 12523-12529. DOI: 10.1021/ja002238t  1
2000 Yu SM, Soto CM, Tirrell DA. Nanometer-scale smectic ordering of genetically engineered rodlike polymers: Synthesis and characterization of monodisperse derivatives of poly(γ-benzyl α,L-glutamate) Journal of the American Chemical Society. 122: 6552-6559. DOI: 10.1021/ja000465p  1
2000 Ghadiri MR, Tirrell DA. Editorial overview: Chemistry at the crossroads Current Opinion in Chemical Biology. 4: 661-662. DOI: 10.1016/S1367-5931(00)00156-3  1
2000 Linhardt JG, Tirrell DA. Characterization of poly(2-ethylacrylic acid) for use in drug delivery Acs Symposium Series. 752: 243-252.  1
2000 Stevens MM, Allen S, Davies MC, Gaub HE, Oesterhelt F, Roberts CJ, Sakata J, Tendler SJB, Tirrell DA, Williams PM. Atomic force microscopy investigations of self-assembling artificial proteins forming reversible hydrogels Journal of Pharmacy and Pharmacology. 52: 199.  1
2000 Kiick KL, Tirrell DA. Protein engineering by in vivo incorporation of non-natural amino acids: Control of incorporation of methionine analogues by methionyl-tRNA synthetase Tetrahedron. 56: 9487-9493.  1
2000 Kennedy SB, Russell TP, Tirrell DA. Engineering dynamic structure and activity in artificial protein hydrogels American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 41: 1665-1666.  1
1999 Murthy N, Robichaud JR, Tirrell DA, Stayton PS, Hoffman AS. The design and synthesis of polymers for eukaryotic membrane disruption. Journal of Controlled Release : Official Journal of the Controlled Release Society. 61: 137-43. PMID 10469910 DOI: 10.1016/S0168-3659(99)00114-5  1
1999 Lackey CA, Murthy N, Press OW, Tirrell DA, Hoffman AS, Stayton PS. Hemolytic activity of pH-responsive polymer-streptavidin bioconjugates. Bioconjugate Chemistry. 10: 401-5. PMID 10346870 DOI: 10.1021/bc980109k  1
1999 Linhardt JG, Thomas JL, Tirrell DA. Free-radical synthesis of poly(2-ethylacrylic acid) fractions of low polydispersity: effects of molecular weight and polydispersity on the pH-dependent conformational transition in aqueous solutions Macromolecules. 32: 4457-4459. DOI: 10.1021/ma990110u  1
1999 Fukuto M, Heilmann RK, Pershan PS, Yu SM, Griffiths JA, Tirrell DA. Structure of poly(γ-benzyl-L-glutamate) monolayers at the gas-water interface: A Brewster angle microscopy and x-ray scattering study Journal of Chemical Physics. 111: 9761-9777.  1
1999 Panitch A, Yamaoka T, Fournier MJ, Mason TL, Tirrell DA. Design and Biosynthesis of Elastin-like Artificial Extracellular Matrix Proteins Containing Periodically Spaced Fibronectin CS5 Domains Macromolecules. 32: 1701-1703.  1
1999 Kim J, Tirrell DA. Synthesis of Well-Defined Poly(2-ethylacrylic acid) Macromolecules. 32: 945-948.  1
1999 Petka WA, Harden JL, Sakata JK, Tirrell DA. Artificial protein hydrogel materials Materials Research Society Symposium - Proceedings. 550: 23-28.  1
1999 Lackey CA, Murthy N, Stayton PS, Press OW, Hoffman AS, Tirrell DA. Enhancement of endosomal release and toxic activity of Ricin A chain by a pH-sensitive polymer Proceedings of the Controlled Release Society. 815-816.  1
1998 Parkhe AD, Cooper SJ, Atkins ED, Fournier MJ, Mason TL, Tirrell DA. Effect of local sequence inversions on the crystalline antiparallel beta-sheet lamellar structures of periodic polypeptides: implications for chain-folding. International Journal of Biological Macromolecules. 23: 251-8. PMID 9849622 DOI: 10.1016/S0141-8130(98)00054-3  1
1998 Petka WA, Harden JL, McGrath KP, Wirtz D, Tirrell DA. Reversible hydrogels from self-assembling artificial proteins. Science (New York, N.Y.). 281: 389-92. PMID 9665877 DOI: 10.1126/science.281.5375.389  1
1998 van Hest JC, Tirrell DA. Efficient introduction of alkene functionality into proteins in vivo. Febs Letters. 428: 68-70. PMID 9645477 DOI: 10.1016/S0014-5793(98)00489-X  1
1998 Beecher JE, Tirrell DA. Synthesis of protected derivatives of 3-pyrrolylalanine Tetrahedron Letters. 39: 3927-3930. DOI: 10.1016/S0040-4039(98)00722-9  1
1998 He SJ, Lee C, Gido SP, Yu SM, Tirrell DA. A twist grain boundary-like twisted smectic phase in monodisperse poly(γ-benzyl α,L-glutamate) produced by recombinant DNA techniques Macromolecules. 31: 9387-9389.  1
1998 Macknight WJ, Ponomarenko EA, Tirrell DA. Self-Assembled Polyelectrolyte - Surfactant Complexes in Nonaqueous Solvents and in the Solid State Accounts of Chemical Research. 31: 781-788.  1
1998 Fukuto M, Heilmann RK, Pershan PS, Griffiths JA, Yu SM, Tirrell DA. X-ray measurements of noncapillary spatial fluctuations from a liquid surface Physical Review Letters. 81: 3455-3458.  1
1998 Gower LA, Tirrell DA. Calcium carbonate films and helices grown in solutions of poly(aspartate) Journal of Crystal Growth. 191: 153-160.  1
1998 Kiick-Fischer KL, Tirrell DA. Controlling absorbency in gelatin networks: Preparation and characterization of alkylated, crosslinked gelatin Journal of Applied Polymer Science. 68: 281-292.  1
1998 Ponomarenko EA, Tirrell DA, MacKnight WJ. Water-insoluble complexes of poly(L-lysine) with mixed alkyl sulfates: Composition-controlled solid state structures Macromolecules. 31: 1584-1589.  1
1998 Lackey CA, Murthy N, Stayton PS, Press OW, Hoffman AS, Tirrell DA. Stimuli-responsive biomolecular conjugates: Controlled membrane disruption Proceedings of the Controlled Release Society. 87-88.  1
1998 Murthy N, Robichaud J, Stayton PS, Press OW, Hoffman AS, Tirrell DA. Design of polymers to increase the efficiency of endosomal release of drugs Proceedings of the Controlled Release Society. 224-225.  1
1997 Tirrell DA. Polymer synthesis. For the living there is hope. Nature. 390: 336-7, 339. PMID 9389469 DOI: 10.1038/36981  1
1997 Yu SM, Conticello VP, Zhang G, Kayser C, Fournier MJ, Mason TL, Tirrell DA. Smectic ordering in solutions and films of a rod-like polymer owing to monodispersity of chain length. Nature. 389: 167-70. PMID 9296493 DOI: 10.1038/38254  1
1997 Cantor EJ, Atkins ED, Cooper SJ, Fournier MJ, Mason TL, Tirrell DA. Effects of amino acid side-chain volume on chain packing in genetically engineered periodic polypeptides. Journal of Biochemistry. 122: 217-25. PMID 9276692  1
1997 Dawson SL, Tirrell DA. Peptide-derived self-assembled monolayers: adsorption of N-stearoyl L-cysteine methyl ester on gold. Journal of Molecular Recognition : Jmr. 10: 18-25. PMID 9179776 DOI: 10.1002/(SICI)1099-1352(199701/02)10:1<18::AID-JMR349>3.0.CO;2-W  1
1997 Deming TJ, Fournier MJ, Mason TL, Tirrell DA. Biosynthetic incorporation and chemical modification of alkene functionality in genetically engineered polymers Journal of Macromolecular Science - Pure and Applied Chemistry. 34: 2143-2150.  1
1997 Chen H, Hsu SL, Tirrell DA, Stidham HD. A pH dependent coil-to-sheet transition in a periodic artificial protein adsorbed at the air-water interface Langmuir. 13: X-4778.  1
1997 Krejchi MT, Cooper SJ, Deguchi Y, Atkins EDT, Fournier MJ, Mason TL, Tirrell DA. Crystal structures of chain-folded antiparallel β-sheet assemblies from sequence-designed periodic polypeptides Macromolecules. 30: 5012-5024.  1
1997 Panitch A, Matsuki K, Cantor EJ, Cooper SJ, Atkins EDT, Fournier MJ, Mason TL, Tirrell DA. Poly(L-alanylglycine): Multigram-scale biosynthesis, crystallization, and structural analysis of chain-folded lamellae Macromolecules. 30: 42-49.  1
1996 Thomas JL, Devlin BP, Tirrell DA. Kinetics of membrane micellization by the hydrophobic polyelectrolyte poly(2-ethylacrylic acid). Biochimica Et Biophysica Acta. 1278: 73-8. PMID 8611610  0.56
1996 Ponomarenko EA, Tirrell DA, MacKnight WJ. Stoichiometric complexes of synthetic polypeptides and oppositely charged surfactants in organic solvents and in the solid state Macromolecules. 29: 8751-8758.  1
1994 Thomas JL, Barton SW, Tirrell DA. Membrane solubilization by a hydrophobic polyelectrolyte: surface activity and membrane binding. Biophysical Journal. 67: 1101-6. PMID 7811920 DOI: 10.1016/S0006-3495(94)80575-2  0.56
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