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Allyn T. Londregan, Ph.D. - Publications

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
New Synthetic Pathways
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Futatsugi K, Cabral S, Kung DW, Huard K, Lee E, Boehm M, Bauman J, Clark RW, Coffey SB, Crowley C, Dechert-Schmitt AM, Dowling MS, Dullea R, Gosset JR, Kalgutkar AS, ... ... Londregan AT, et al. Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis. Journal of Medicinal Chemistry. PMID 36322383 DOI: 10.1021/acs.jmedchem.2c01200  0.465
2021 Aspnes GE, Menhaji-Klotz E, Boehm M, Londregan AT, Lee ECY, Limberakis C, Coffey SB, Brown JA, Jones RM, Hesp KD. Discovery and Evaluation of Non-Basic Small Molecule Modulators of the Atypical Chemokine Receptor CXCR7. Bioorganic & Medicinal Chemistry Letters. 128320. PMID 34400299 DOI: 10.1016/j.bmcl.2021.128320  0.39
2015 Ammirati M, Bagley SW, Bhattacharya SK, Buckbinder L, Carlo AA, Conrad R, Cortes C, Dow RL, Dowling MS, El-Kattan A, Ford K, Guimarães CR, Hepworth D, Jiao W, LaPerle J, ... ... Londregan A, et al. Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment. Acs Medicinal Chemistry Letters. 6: 1128-1133. PMID 26617966 DOI: 10.1021/Acsmedchemlett.5B00215  0.6
2014 Bhattacharya SK, Andrews K, Beveridge R, Cameron KO, Chen C, Dunn M, Fernando D, Gao H, Hepworth D, Jackson VM, Khot V, Kong J, Kosa RE, Lapham K, Loria PM, ... Londregan AT, et al. Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate. Acs Medicinal Chemistry Letters. 5: 474-9. PMID 24900864 DOI: 10.1021/ml400473x  0.571
2013 Londregan AT, Piotrowski DW, Futatsugi K, Warmus JS, Boehm M, Carpino PA, Chin JE, Janssen AM, Roush NS, Buxton J, Hinchey T. Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries. Bioorganic & Medicinal Chemistry Letters. 23: 1407-11. PMID 23337601 DOI: 10.1016/j.bmcl.2012.12.076  0.322
2012 Fernando DP, Jiao W, Polivkova J, Xiao J, Coffey SB, Rose C, Londregan A, Saenz J, Beveridge R, Zhang Y, Storer GE, Vrieze D, Erasga N, Jones R, Khot V, et al. Spiroazetidine-piperidine bromoindane as a key modular template to access a variety of compounds via C-C and C-N bond-forming reactions Tetrahedron Letters. 53: 6351-6354. DOI: 10.1016/j.tetlet.2012.09.047  0.544
2007 Winkler JD, Londregan AT, Hamann MT. Synthetic modification of manzamine A via Grubbs metathesis. Novel structures with enhanced antibacterial and antiprotozoal properties. Organic Letters. 9: 4467-9. PMID 17918854 DOI: 10.1021/Ol701799C  0.496
2006 Winkler JD, Londregan AT, Ragains JR, Hamann MT. Synthesis and biological evaluation of manzamine analogues. Organic Letters. 8: 3407-9. PMID 16836417 DOI: 10.1021/Ol061320B  0.584
2006 Winkler JD, Londregan AT, Hamann MT. Antimalarial activity of a new family of analogues of manzamine A. Organic Letters. 8: 2591-4. PMID 16737321 DOI: 10.1021/Ol060848D  0.53
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