Vadim Y. Dudkin, Ph.D. - Publications

Affiliations: 
2001 University of Illinois at Chicago, Chicago, IL, United States 
Area:
diastereoselective free radical chemistry, acyl radical chemistry, enantioselective synthesis of á-disubstituted amino acids, and carbohydrate chemistry

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

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Year Citation  Score
2016 Layton ME, Reif AJ, Hartingh TJ, Rodzinak K, Dudkin V, Wang C, Arrington K, Kelly MJ, Garbaccio RM, O'Brien JA, Magliaro BC, Uslaner JM, Huszar SL, Fillgrove KL, Tang C, et al. Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. Bioorganic & Medicinal Chemistry Letters. PMID 26810316 DOI: 10.1016/j.bmcl.2016.01.021  1
2012 Dudkin VY, Rickert K, Kreatsoulas C, Wang C, Arrington KL, Fraley ME, Hartman GD, Yan Y, Ikuta M, Stirdivant SM, Drakas RA, Walsh ES, Hamilton K, Buser CA, Lobell RB, et al. Pyridyl aminothiazoles as potent inhibitors of Chk1 with slow dissociation rates. Bioorganic & Medicinal Chemistry Letters. 22: 2609-12. PMID 22374217 DOI: 10.1016/j.bmcl.2012.01.110  1
2012 Dudkin VY, Wang C, Arrington KL, Fraley ME, Hartman GD, Stirdivant SM, Drakas RA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, et al. Pyridyl aminothiazoles as potent Chk1 inhibitors: optimization of cellular activity. Bioorganic & Medicinal Chemistry Letters. 22: 2613-9. PMID 22365762 DOI: 10.1016/j.bmcl.2012.01.120  1
2010 Caulfield MJ, Dudkin VY, Ottinger EA, Getty KL, Zuck PD, Kaufhold RM, Hepler RW, McGaughey GB, Citron M, Hrin RC, Wang YJ, Miller MD, Joyce JG. Small molecule mimetics of an HIV-1 gp41 fusion intermediate as vaccine leads. The Journal of Biological Chemistry. 285: 40604-11. PMID 20943652 DOI: 10.1074/jbc.M110.172197  1
2008 Joyce JG, Krauss IJ, Song HC, Opalka DW, Grimm KM, Nahas DD, Esser MT, Hrin R, Feng M, Dudkin VY, Chastain M, Shiver JW, Danishefsky SJ. An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions. Proceedings of the National Academy of Sciences of the United States of America. 105: 15684-9. PMID 18838688 DOI: 10.1073/pnas.0807837105  1
2008 Dudkin VY, Miller JS, Dudkina AS, Antczak C, Scheinberg DA, Danishefsky SJ. Toward a prostate specific antigen-based prostate cancer diagnostic assay: preparation of keyhole limpet hemocyanin-conjugated normal and transformed prostate specific antigen fragments. Journal of the American Chemical Society. 130: 13598-607. PMID 18798614 DOI: 10.1021/ja8028137  1
2007 Brnardic EJ, Garbaccio RM, Fraley ME, Tasber ES, Steen JT, Arrington KL, Dudkin VY, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, et al. Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 5989-94. PMID 17804227 DOI: 10.1016/j.bmcl.2007.07.051  1
2007 Krauss IJ, Joyce JG, Finnefrock AC, Song HC, Dudkin VY, Geng X, Warren JD, Chastain M, Shiver JW, Danishefsky SJ. Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody. Journal of the American Chemical Society. 129: 11042-4. PMID 17711286 DOI: 10.1021/ja074804r  1
2006 Wang ZG, Warren JD, Dudkin VY, Zhang X, Iserloh U, Visser M, Eckhardt M, Seeberger PH, Danishefsky SJ. A highly convergent synthesis of an N-linked glycopeptide presenting the H-type 2 human blood group determinant Tetrahedron. 62: 4954-4978. DOI: 10.1016/j.tet.2006.02.080  1
2004 Dudkin VY, Orlova M, Geng X, Mandal M, Olson WC, Danishefsky SJ. Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency. Journal of the American Chemical Society. 126: 9560-2. PMID 15291558 DOI: 10.1021/ja047720g  1
2004 Geng X, Dudkin VY, Mandal M, Danishefsky SJ. In pursuit of carbohydrate-based HIV vaccines, part 2: The total synthesis of high-mannose-type gp120 fragments--evaluation of strategies directed to maximal convergence. Angewandte Chemie (International Ed. in English). 43: 2562-5. PMID 15127453 DOI: 10.1002/anie.200353626  1
2004 Mandal M, Dudkin VY, Geng X, Danishefsky SJ. In pursuit of carbohydrate-based HIV vaccines, part 1: The total synthesis of hybrid-type gp120 fragments. Angewandte Chemie (International Ed. in English). 43: 2557-61. PMID 15127452 DOI: 10.1002/anie.200353625  1
2003 Miller JS, Dudkin VY, Lyon GJ, Muir TW, Danishefsky SJ. Toward fully synthetic N-linked glycoproteins. Angewandte Chemie (International Ed. in English). 42: 431-4. PMID 12569509 DOI: 10.1002/anie.200390131  1
2003 Dudkin VY, Crich D. A short synthesis of the trisaccharide building block of the N-linked glycans Tetrahedron Letters. 44: 1787-1789. DOI: 10.1016/S0040-4039(03)00102-3  1
2002 Crich D, Dudkin V. Confirmation of the connectivity of 4,8,12,16,20-pentamethylpentacosylphoshoryl β-D-mannopyranoside, an unusual β-mannosyl phosphoisoprenoid from Mycobacterium avium, through synthesis Journal of the American Chemical Society. 124: 2263-2266. PMID 11878980 DOI: 10.1021/ja0123958  1
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