Charles Karan, Ph.D. - Publications

2002 University of Rochester, Rochester, NY 
Dynamic combinatorial chemistry, RNA targeting therapeutics

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Jain S, Jirau-Serrano X, Zullo KM, Scotto L, Palermo CF, Sastra SA, Olive KP, Cremers S, Thomas T, Wei Y, Zhang Y, Bhagat G, Amengual JE, Deng C, Karan C, et al. Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2096-106. PMID 25677697 DOI: 10.1158/1078-0432.CCR-14-2249  0.72
2015 Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Elucidating Compound Mechanism of Action by Network Perturbation Analysis Cell. 162: 441-451. DOI: 10.1016/j.cell.2015.05.056  0.72
2014 Bansal M, Yang J, Karan C, Menden MP, Costello JC, Tang H, Xiao G, Li Y, Allen J, Zhong R, Chen B, Kim M, Wang T, Heiser LM, Realubit R, et al. A community computational challenge to predict the activity of pairs of compounds. Nature Biotechnology. 32: 1213-22. PMID 25419740 DOI: 10.1038/Nbt.3052  0.72
2014 Sonabend AM, Carminucci AS, Amendolara B, Bansal M, Leung R, Lei L, Realubit R, Li H, Karan C, Yun J, Showers C, Rothcock R, O J, Califano A, Canoll P, et al. Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. Neuro-Oncology. 16: 1210-9. PMID 24637229 DOI: 10.1093/Neuonc/Nou026  0.72
2008 Blue R, Murcia M, Karan C, Jirousková M, Coller BS. Application of high-throughput screening to identify a novel alphaIIb-specific small- molecule inhibitor of alphaIIbbeta3-mediated platelet interaction with fibrinogen. Blood. 111: 1248-56. PMID 17978171 DOI: 10.1182/blood-2007-08-105544  0.72
2004 Karan C, Tallarico JA. The modular approach to ligand discovery. Chemistry & Biology. 11: 292-3. PMID 15123257 DOI: 10.1016/j.chembiol.2004.03.002  0.72
2001 Karan C, Miller BL. RNA-selective coordination complexes identified via dynamic combinatorial chemistry. Journal of the American Chemical Society. 123: 7455-6. PMID 11472190 DOI: 10.1021/Ja010325V  0.72
2001 Hari A, Karan C, Rodrigues WC, Miller BL. Extending the scope of chromium-manganese redox-coupled reactions: a one-pot synthesis of benzoxazoles. The Journal of Organic Chemistry. 66: 991-6. PMID 11430122 DOI: 10.1021/Jo005758F  0.72
2000 Karan C, Miller BL. Dynamic diversity in drug discovery: Putting small-molecule evolution to work Drug Discovery Today. 5: 67-75. DOI: 10.1016/S1359-6446(99)01431-2  0.72
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