Year |
Citation |
Score |
2019 |
Tang H, Shah K, Steinmetz T, Abraham A, Jensen H, Bouton A, Marullo K, Shi S. Development and validation of a multiplexed drug level assay in support of combination biologics therapy clinical studies. Journal of Pharmaceutical and Biomedical Analysis. 171: 204-211. PMID 31009875 DOI: 10.1016/J.Jpba.2019.04.021 |
0.339 |
|
2017 |
Tiwari A, Abraham AK, Harrold JM, Zutshi A, Singh P. Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling. The Aaps Journal. PMID 28097628 DOI: 10.1208/S12248-017-0046-Z |
0.336 |
|
2016 |
Tiwari A, Abraham AK, Harrold JM, Zutshi A, Singh P. Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling. The Aaps Journal. PMID 28004347 DOI: 10.1208/S12248-016-0004-1 |
0.442 |
|
2015 |
Visintin A, Knowlton K, Tyminski E, Lin CI, Zheng X, Marquette K, Jain S, Tchistiakova L, Li D, O'Donnell CJ, Maderna A, Cao X, Dunn R, Snyder WB, Abraham AK, et al. Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature. Molecular Cancer Therapeutics. PMID 26089370 DOI: 10.1158/1535-7163.Mct-15-0188 |
0.301 |
|
2015 |
Chudasama VL, Zutshi A, Singh P, Abraham AK, Mager DE, Harrold JM. Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies. Journal of Pharmacokinetics and Pharmacodynamics. 42: 1-18. PMID 25559227 DOI: 10.1007/S10928-014-9401-1 |
0.465 |
|
2015 |
Singh AP, Krzyzanski W, Martin SW, Weber G, Betts A, Ahmad A, Abraham A, Zutshi A, Lin J, Singh P. Quantitative prediction of human pharmacokinetics for mAbs exhibiting target-mediated disposition. The Aaps Journal. 17: 389-99. PMID 25445845 DOI: 10.1208/S12248-014-9690-8 |
0.424 |
|
2014 |
Harrold JM, Abraham AK. Ubiquity: a framework for physiological/mechanism-based pharmacokinetic/pharmacodynamic model development and deployment. Journal of Pharmacokinetics and Pharmacodynamics. 41: 141-51. PMID 24619141 DOI: 10.1007/S10928-014-9352-6 |
0.352 |
|
2011 |
Abraham AK, Maurer TS, Kalgutkar AS, Gao X, Li M, Healy DR, Petersen DN, Griffith DA, Mager DE. Pharmacodynamic model of parathyroid hormone modulation by a negative allosteric modulator of the calcium-sensing receptor. The Aaps Journal. 13: 265-73. PMID 21437757 DOI: 10.1208/S12248-011-9266-9 |
0.604 |
|
2010 |
Abraham AK, Kagan L, Kumar S, Mager DE. Type I interferon receptor is a primary regulator of target-mediated drug disposition of interferon-beta in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 327-32. PMID 20406858 DOI: 10.1124/Jpet.110.167650 |
0.584 |
|
2010 |
Kagan L, Abraham AK, Harrold JM, Mager DE. Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons. Pharmaceutical Research. 27: 920-32. PMID 20232116 DOI: 10.1007/S11095-010-0098-6 |
0.569 |
|
2009 |
Abraham AK, Ramanathan M, Weinstock-Guttman B, Mager DE. Mechanisms of interferon-beta effects on bone homeostasis. Biochemical Pharmacology. 77: 1757-62. PMID 19428330 DOI: 10.1016/J.Bcp.2009.01.007 |
0.509 |
|
2009 |
Abraham AK, Mager DE, Gao X, Li M, Healy DR, Maurer TS. Mechanism-based pharmacokinetic/pharmacodynamic model of parathyroid hormone-calcium homeostasis in rats and humans. The Journal of Pharmacology and Experimental Therapeutics. 330: 169-78. PMID 19386792 DOI: 10.1124/Jpet.109.152033 |
0.553 |
|
2007 |
Abraham AK, Krzyzanski W, Mager DE. Partial derivative-based sensitivity analysis of models describing target-mediated drug disposition. The Aaps Journal. 9: E181-9. PMID 17614360 DOI: 10.1208/Aapsj0902020 |
0.596 |
|
2007 |
Abraham AK, Krzyzanski W, Mage DE. Partial derivative - Based sensitivity analysis of models describing target-mediated drug disposition Aaps Journal. 9. |
0.327 |
|
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