Jessica A. Brown, Ph.D. - Publications

Affiliations: 
2010 Biochemistry Program, Ohio State Ohio State University, Columbus, Columbus, OH 
Area:
enzymes involved in DNA/RNA replication, Hepatitis C replication, drug design

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kunkler CN, Schiefelbein GE, O'Leary NJ, McCown PJ, Brown JA. A single natural RNA modification can destabilize a U•A-T-rich RNA•DNA-DNA triple helix. Rna (New York, N.Y.). PMID 35820700 DOI: 10.1261/rna.079244.122  0.459
2019 Kunkler CN, Hulewicz JP, Hickman SC, Wang MC, McCown PJ, Brown JA. Stability of an RNA•DNA-DNA triple helix depends on base triplet composition and length of the RNA third strand. Nucleic Acids Research. PMID 31265072 DOI: 10.1093/nar/gkz573  0.522
2017 Sundar R, Brown J, Ingles Russo A, Yap TA. Targeting ATR in cancer medicine. Current Problems in Cancer. PMID 28662958 DOI: 10.1016/j.currproblcancer.2017.05.002  0.414
2015 Leung GP, Brown JA, Glover JN, Kobor MS. Rtt107 BRCT domains act as a targeting module in the DNA damage response. Dna Repair. 37: 22-32. PMID 26641499 DOI: 10.1016/J.Dnarep.2015.10.007  0.472
2012 Brown JA, Pack LR, Fowler JD, Suo Z. Presteady state kinetic investigation of the incorporation of anti-hepatitis B nucleotide analogues catalyzed by noncanonical human DNA polymerases. Chemical Research in Toxicology. 25: 225-33. PMID 22132702 DOI: 10.1021/Tx200458S  0.737
2011 Brown JA, Suo Z. Unlocking the sugar "steric gate" of DNA polymerases. Biochemistry. 50: 1135-42. PMID 21226515 DOI: 10.1021/Bi101915Z  0.752
2011 Brown JA, Pack LR, Fowler JD, Suo Z. Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases. Antimicrobial Agents and Chemotherapy. 55: 276-83. PMID 21078938 DOI: 10.1128/Aac.01229-10  0.732
2011 Brown JA, Pack LR, Sanman LE, Suo Z. Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis. Dna Repair. 10: 24-33. PMID 20961817 DOI: 10.1016/J.Dnarep.2010.09.005  0.744
2010 Brown JA, Pack LR, Sherrer SM, Kshetry AK, Newmister SA, Fowler JD, Taylor JS, Suo Z. Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ. Journal of Molecular Biology. 403: 505-15. PMID 20851705 DOI: 10.1016/J.Jmb.2010.09.014  0.723
2010 Brown JA, Zhang L, Sherrer SM, Taylor JS, Burgers PM, Suo Z. Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Journal of Nucleic Acids. 2010. PMID 20798853 DOI: 10.4061/2010/871939  0.738
2010 Brown JA, Fowler JD, Suo Z. Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. Biochemistry. 49: 5504-10. PMID 20518555 DOI: 10.1021/Bi100433X  0.731
2010 Wong JH, Brown JA, Suo Z, Blum P, Nohmi T, Ling H. Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. The Embo Journal. 29: 2059-69. PMID 20512114 DOI: 10.1038/Emboj.2010.101  0.695
2010 Brown JA, Fiala KA, Fowler JD, Sherrer SM, Newmister SA, Duym WW, Suo Z. A novel mechanism of sugar selection utilized by a human X-family DNA polymerase. Journal of Molecular Biology. 395: 282-90. PMID 19900463 DOI: 10.1016/J.Jmb.2009.11.003  0.786
2009 Xu C, Maxwell BA, Brown JA, Zhang L, Suo Z. Global conformational dynamics of a Y-family DNA polymerase during catalysis. Plos Biology. 7: e1000225. PMID 19859523 DOI: 10.1371/Journal.Pbio.1000225  0.747
2009 Fowler JD, Brown JA, Kvaratskhelia M, Suo Z. Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting. Journal of Molecular Biology. 390: 368-79. PMID 19467241 DOI: 10.1016/J.Jmb.2009.05.037  0.719
2009 Brown JA, Suo Z. Elucidating the kinetic mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase B1. Biochemistry. 48: 7502-11. PMID 19456143 DOI: 10.1021/Bi9005336  0.731
2009 Zhang L, Brown JA, Newmister SA, Suo Z. Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2. Biochemistry. 48: 7492-501. PMID 19456141 DOI: 10.1021/Bi900532W  0.675
2009 Sherrer SM, Brown JA, Pack LR, Jasti VP, Fowler JD, Basu AK, Suo Z. Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. The Journal of Biological Chemistry. 284: 6379-88. PMID 19124465 DOI: 10.1074/Jbc.M808161200  0.716
2008 Brown JA, Newmister SA, Fiala KA, Suo Z. Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase. Nucleic Acids Research. 36: 3867-78. PMID 18499711 DOI: 10.1093/Nar/Gkn309  0.787
2008 Fowler JD, Brown JA, Johnson KA, Suo Z. Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 283: 15339-48. PMID 18378680 DOI: 10.1074/Jbc.M800310200  0.762
2008 Fiala KA, Sherrer SM, Brown JA, Suo Z. Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase. Nucleic Acids Research. 36: 1990-2001. PMID 18276639 DOI: 10.1093/Nar/Gkn004  0.735
2007 Brown JA, Duym WW, Fowler JD, Suo Z. Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta. Journal of Molecular Biology. 367: 1258-69. PMID 17321545 DOI: 10.1016/J.Jmb.2007.01.069  0.745
2007 Fiala KA, Brown JA, Ling H, Kshetry AK, Zhang J, Taylor JS, Yang W, Suo Z. Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Journal of Molecular Biology. 365: 590-602. PMID 17095011 DOI: 10.1016/J.Jmb.2006.10.008  0.79
2003 Edwards S, Li CM, Levy DL, Brown J, Snow PM, Campbell JL. Saccharomyces cerevisiae DNA polymerase epsilon and polymerase sigma interact physically and functionally, suggesting a role for polymerase epsilon in sister chromatid cohesion. Molecular and Cellular Biology. 23: 2733-48. PMID 12665575 DOI: 10.1128/MCB.23.8.2733-2748.2003  0.468
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