Wei Yang - Publications

Molecular Biology National Institutes of Health, Bethesda, MD 

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Frank EG, McDonald JP, Yang W, Woodgate R. Mouse DNA polymerase ι lacking the forty-two amino acids encoded by exon-2 is catalytically inactive in vitro. Dna Repair. PMID 28077247 DOI: 10.1016/J.Dnarep.2016.12.004  0.304
2016 Gao Y, Yang W. Capture of a third Mg²⁺ is essential for catalyzing DNA synthesis. Science (New York, N.Y.). 352: 1334-7. PMID 27284197 DOI: 10.1126/Science.Aad9633  0.356
2015 Fu W, Wang X, Yang W, Takeda H, Hu S, Lou Z, Zhao J, Bethune AN, Guo Y. Retraction Note to: Structure-based development and optimization of therapy antibody drugs against TNFα. Amino Acids. PMID 26650200 DOI: 10.1007/s00726-015-2147-2  0.369
2015 Chen W, Guo Y, Yang W, Zheng P, Zeng J, Tong W. Involvement of Connexin40 in the Protective Effects of Ginsenoside Rb1 Against Traumatic Brain Injury. Cellular and Molecular Neurobiology. PMID 26645822 DOI: 10.1007/s10571-015-0299-y  0.387
2015 Yang W, Lee YS. A DNA-hairpin model for repeat-addition processivity in telomere synthesis. Nature Structural & Molecular Biology. 22: 844-847. PMID 26581517 DOI: 10.1038/Nsmb.3098  0.339
2015 Zou Y, Liu XM, Zhang L, Chen YM, Guo Y, Chen XJ, Yang WY, Wang SC, Ruan M, Liu TF, Zhang JY, Liu F, Qi BQ, Zhu XF. [Significance of IKZF1 gene copy number abnormalities in BCR/ABL-negative B-lineage acute lymphoblastic leukemia in children]. Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics. 17: 1154-1159. PMID 26575870 DOI: 10.7499/j.issn.1008-8830.2015.11.002  0.359
2015 Xue T, Yang W, Guo Y, Yuan W, Dai J, Zhao Z. 3D Image-Guided Percutaneous Radiofrequency Thermocoagulation of the Maxillary Branch of the Trigeminal Nerve Through Foramen Rotundum for the Treatment of Trigeminal Neuralgia. Medicine. 94: e1954. PMID 26559267 DOI: 10.1097/MD.0000000000001954  0.369
2015 Li F, Yin Z, Zhou B, Xue F, Yang W, Chang R, Ma K, Qiu Y. Shikonin inhibits inflammatory responses in rabbit chondrocytes and shows chondroprotection in osteoarthritic rabbit knee. International Immunopharmacology. PMID 26395917 DOI: 10.1016/j.intimp.2015.09.014  0.396
2015 Li CL, Golebiowski FM, Onishi Y, Samara NL, Sugasawa K, Yang W. Tripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision Repair. Molecular Cell. 59: 1025-34. PMID 26384665 DOI: 10.1016/J.Molcel.2015.08.012  0.342
2015 Lapkouski M, Chuenchor W, Kim MS, Gellert M, Yang W. Assembly Pathway and Characterization of the RAG1/2-DNA Paired and Signal-end Complexes. The Journal of Biological Chemistry. 290: 14618-25. PMID 25903130 DOI: 10.1074/Jbc.M115.641787  0.361
2015 Lee YS, Gao Y, Yang W. How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nature Structural & Molecular Biology. 22: 298-303. PMID 25775266 DOI: 10.1038/Nsmb.2985  0.37
2014 Gregory MT, Park GY, Johnstone TC, Lee YS, Yang W, Lippard SJ. Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 111: 9133-8. PMID 24927576 DOI: 10.1073/Pnas.1405739111  0.368
2014 Yang W. An overview of Y-family DNA polymerases and a case study of human DNA polymerase π Biochemistry. 53: 2793-2803. PMID 24716551 DOI: 10.1021/Bi500019S  0.349
2014 Lee YS, Gregory MT, Yang W. Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass. Proceedings of the National Academy of Sciences of the United States of America. 111: 2954-9. PMID 24449906 DOI: 10.1073/Pnas.1324001111  0.35
2014 Liu Y, Yang Y, Tang TS, Zhang H, Wang Z, Friedberg E, Yang W, Guo C. Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[a]pyrene dG adduct. Proceedings of the National Academy of Sciences of the United States of America. 111: 1789-94. PMID 24449898 DOI: 10.1073/Pnas.1324168111  0.35
2013 Mizuno N, Drami?anin M, Mizuuchi M, Adam J, Wang Y, Han YW, Yang W, Steven AC, Mizuuchi K, Ramón-Maiques S. MuB is an AAA+ ATPase that forms helical filaments to control target selection for DNA transposition. Proceedings of the National Academy of Sciences of the United States of America. 110: E2441-50. PMID 23776210 DOI: 10.1073/Pnas.1309499110  0.37
2013 Zhao Y, Gregory MT, Biertümpfel C, Hua YJ, Hanaoka F, Yang W. Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η. Proceedings of the National Academy of Sciences of the United States of America. 110: 8146-51. PMID 23630267 DOI: 10.1073/Pnas.1303126110  0.308
2013 Li F, Mao G, Tong D, Huang J, Gu L, Yang W, Li GM. The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα Cell. 153: 590-600. PMID 23622243 DOI: 10.1016/J.Cell.2013.03.025  0.336
2013 Lapkouski M, Tian L, Miller JT, Le Grice SFJ, Yang W. Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation Nature Structural and Molecular Biology. 20: 230-236. PMID 23314251 DOI: 10.1038/Nsmb.2485  0.344
2013 Nakamura T, Zhao Y, Yamagata Y, Hua YJ, Yang W. Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography Biophysics (Japan). 9: 31-36. DOI: 10.2142/Biophysics.9.31  0.335
2012 Zheng L, Yang W. Practically Efficient and Robust Free Energy Calculations: Double-Integration Orthogonal Space Tempering. Journal of Chemical Theory and Computation. 8: 810-23. PMID 26593343 DOI: 10.1021/Ct200726V  0.3
2012 Yin Z, Lapkouski M, Yang W, Craigie R. Assembly of prototype foamy virus strand transfer complexes on product DNA bypassing catalysis of integration. Protein Science : a Publication of the Protein Society. 21: 1849-57. PMID 23011895 DOI: 10.1002/Pro.2166  0.346
2012 Nakamura T, Zhao Y, Yamagata Y, Hua YJ, Yang W. Watching DNA polymerase η make a phosphodiester bond Nature. 487: 196-201. PMID 22785315 DOI: 10.1038/Nature11181  0.329
2012 Zhao Y, Biertümpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin Proceedings of the National Academy of Sciences of the United States of America. 109: 7269-7274. PMID 22529383 DOI: 10.1073/Pnas.1202681109  0.387
2012 Vaisman A, Kuban W, McDonald JP, Karata K, Yang W, Goodman MF, Woodgate R. Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity. Nucleic Acids Research. 40: 6144-57. PMID 22422840 DOI: 10.1093/Nar/Gks233  0.352
2012 Gupta S, Gellert M, Yang W. Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops. Nature Structural & Molecular Biology. 19: 72-8. PMID 22179786 DOI: 10.1038/Nsmb.2175  0.374
2011 Yang W. Surviving the sun: Repair and bypass of DNA UV lesions Protein Science. 20: 1781-1789. PMID 21898645 DOI: 10.1002/Pro.723  0.347
2010 Min D, Zheng L, Harris W, Chen M, Lv C, Yang W. Practically Efficient QM/MM Alchemical Free Energy Simulations: The Orthogonal Space Random Walk Strategy. Journal of Chemical Theory and Computation. 6: 2253-66. PMID 26613484 DOI: 10.1021/Ct100033S  0.303
2010 Grundy GJ, Yang W, Gellert M. Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination Proceedings of the National Academy of Sciences of the United States of America. 107: 22487-22492. PMID 21149691 DOI: 10.1073/Pnas.1014958107  0.362
2010 Yang W, Cui Q, Min D, Li H. QM/MM Alchemical free energy simulations. Challenges and recent developments Annual Reports in Computational Chemistry. 6: 51-62. DOI: 10.1016/S1574-1400(10)06004-4  0.307
2009 Wang F, Yang W. Structural Insight into Translesion Synthesis by DNA Pol II Cell. 139: 1279-1289. PMID 20064374 DOI: 10.1016/J.Cell.2009.11.043  0.368
2009 Grundy GJ, Ramón-Maiques S, Dimitriadis EK, Kotova S, Biertümpfel C, Heymann JB, Steven AC, Gellert M, Yang W. Initial Stages of V(D)J Recombination: The Organization of RAG1/2 and RSS DNA in the Postcleavage Complex Molecular Cell. 35: 217-227. PMID 19647518 DOI: 10.1016/J.Molcel.2009.06.022  0.342
2008 Zheng L, Chen M, Yang W. Random walk in orthogonal space to achieve efficient free-energy simulation of complex systems. Proceedings of the National Academy of Sciences of the United States of America. 105: 20227-32. PMID 19075242 DOI: 10.1073/Pnas.0810631106  0.305
2008 Zheng L, Carbone IO, Lugovskoy A, Berg BA, Yang W. A hybrid recursion method to robustly ensure convergence efficiencies in the simulated scaling based free energy simulations. The Journal of Chemical Physics. 129: 034105. PMID 18647014 DOI: 10.1063/1.2953321  0.302
2008 Zheng L, Yang W. Essential energy space random walks to accelerate molecular dynamics simulations: convergence improvements via an adaptive-length self-healing strategy. The Journal of Chemical Physics. 129: 014105. PMID 18624468 DOI: 10.1063/1.2949815  0.307
2008 Nowotny M, Cerritelli SM, Ghirlando R, Gaidamakov SA, Crouch RJ, Yang W. Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD Embo Journal. 27: 1172-1181. PMID 18337749 DOI: 10.1038/Emboj.2008.44  0.352
2007 Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, et al. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 450: 1106-10. PMID 18033247 DOI: 10.1038/Nature06431  0.325
2007 Yang W, Woodgate R. What a difference a decade makes: Insights into translesion DNA synthesis Proceedings of the National Academy of Sciences of the United States of America. 104: 15591-15598. PMID 17898175 DOI: 10.1073/Pnas.0704219104  0.376
2007 Biertümpfel C, Yang W, Suck D. Crystal structure of T4 endonuclease VII resolving a Holliday junction Nature. 449: 616-620. PMID 17873859 DOI: 10.1038/Nature06152  0.371
2007 Min D, Liu Y, Carbone I, Yang W. On the convergence improvement in the metadynamics simulations: a Wang-Landau recursion approach. The Journal of Chemical Physics. 126: 194104. PMID 17523795 DOI: 10.1063/1.2731769  0.309
2007 Li H, Min D, Shore SG, Lipscomb WN, Yang W. Nature of "hydrogen bond" in the diborane-benzene complex: covalent, electrostatic, or dispersive? Inorganic Chemistry. 46: 3956-9. PMID 17428045 DOI: 10.1021/Ic061857L  0.327
2007 Li H, Yang W. Sampling enhancement for the quantum mechanical potential based molecular dynamics simulations: A general algorithm and its extension for free energy calculation on rugged energy surface Journal of Chemical Physics. 126: 114104-114104. PMID 17381193 DOI: 10.1063/1.2710790  0.306
2007 Yang W. Human MutLα: The jack of all trades in MMR is also an endonuclease Dna Repair. 6: 135-139. PMID 17142111 DOI: 10.1016/J.Dnarep.2006.10.021  0.301
2007 Fiala KA, Brown JA, Ling H, Kshetry AK, Zhang J, Taylor JS, Yang W, Suo Z. Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Journal of Molecular Biology. 365: 590-602. PMID 17095011 DOI: 10.1016/J.Jmb.2006.10.008  0.381
2006 Lee JY, Yang W. UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Cell. 127: 1349-1360. PMID 17190599 DOI: 10.1016/J.Cell.2006.10.049  0.373
2006 Yang W, Lee JY, Nowotny M. Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity Molecular Cell. 22: 5-13. PMID 16600865 DOI: 10.1016/J.Molcel.2006.03.013  0.309
2006 Yang W. Poor base stacking at DNA lesions may initiate recognition by many repair proteins Dna Repair. 5: 654-666. PMID 16574501 DOI: 10.1016/J.Dnarep.2006.02.004  0.356
2005 Jae YL, Chang J, Joseph N, Ghirlando R, Rao DN, Yang W. MutH complexed with hemi- and unmethylated DNAs: Coupling base recognition and DNA cleavage Molecular Cell. 20: 155-166. PMID 16209953 DOI: 10.1016/J.Molcel.2005.08.019  0.379
2005 Vaisman A, Ling H, Woodgate R, Yang W. Fidelity of Dpo4: Effect of metal ions, nucleotide selection and pyrophosphorolysis Embo Journal. 24: 2957-2967. PMID 16107880 DOI: 10.1038/Sj.Emboj.7600786  0.34
2005 Nowotny M, Gaidamakov SA, Crouch RJ, Yang W. Crystal structures of RNase H bound to an RNA/DNA hybrid: Substrate specificity and metal-dependent catalysis Cell. 121: 1005-1016. PMID 15989951 DOI: 10.1016/J.Cell.2005.04.024  0.343
2004 Guarné A, Ramon-Maiques S, Wolff EM, Ghirlando R, Hu X, Miller JH, Yang W. Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair. The Embo Journal. 23: 4134-45. PMID 15470502 DOI: 10.1038/Sj.Emboj.7600412  0.333
2004 Vidal AE, Kannouche P, Podust VN, Yang W, Lehmann AR, Woodgate R. Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. The Journal of Biological Chemistry. 279: 48360-8. PMID 15342632 DOI: 10.1074/Jbc.M406511200  0.377
2004 Boudsocq F, Kokoska RJ, Plosky BS, Vaisman A, Ling H, Kunkel TA, Yang W, Woodgate R. Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. The Journal of Biological Chemistry. 279: 32932-40. PMID 15155753 DOI: 10.1074/Jbc.M405249200  0.35
2004 Ling H, Boudsocq F, Woodgate R, Yang W. Snapshots of replication through an abasic lesion: Structural basis for base substitutions and frameshifts Molecular Cell. 13: 751-762. PMID 15023344 DOI: 10.1016/S1097-2765(04)00101-7  0.374
2004 Ling H, Sayer JM, Plosky BS, Yagi H, Boudsocq F, Woodgate R, Jerina DM, Yang W. Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 101: 2265-9. PMID 14982998 DOI: 10.1073/Pnas.0308332100  0.363
2003 Modesti M, Junop MS, Ghirlando R, van de Rakt M, Gellert M, Yang W, Kanaar R. Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive. Journal of Molecular Biology. 334: 215-28. PMID 14607114 DOI: 10.1016/J.Jmb.2003.09.031  0.375
2003 Ling H, Boudsocq F, Plosky BS, Woodgate R, Yang W. Replication of a cis-syn thymine dimer at atomic resolution. Nature. 424: 1083-7. PMID 12904819 DOI: 10.1038/Nature01919  0.389
2003 Yang W. Damage repair DNA polymerases Y Current Opinion in Structural Biology. 13: 23-30. PMID 12581656 DOI: 10.1016/S0959-440X(02)00003-9  0.387
2002 Boudsocq F, Ling H, Yang W, Woodgate R. Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass Dna Repair. 1: 343-358. PMID 12509239 DOI: 10.1016/S1568-7864(02)00019-8  0.368
2002 Guarné A, Zhao Q, Ghirlando R, Yang W. Insights into negative modulation of E. coli replication initiation from the structure of SeqA-hemimethylated DNA complex Nature Structural Biology. 9: 839-843. PMID 12379844 DOI: 10.1038/Nsb857  0.386
2001 Ling H, Boudsocq F, Woodgate R, Yang W. Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication Cell. 107: 91-102. PMID 11595188 DOI: 10.1016/S0092-8674(01)00515-3  0.385
2001 Biswas I, Obmolova G, Takahashi M, Herr A, Newman MA, Yang W, Hsieh P. Disruption of the helix-u-turn-helix motif of MutS protein: Loss of subunit dimerization, mismatch binding and ATP hydrolysis Journal of Molecular Biology. 305: 805-816. PMID 11162093 DOI: 10.1006/Jmbi.2000.4367  0.337
2000 Yang W, Junop MS, Ban C, Obmolova G, Hsieh P. DNA mismatch repair: From structure to mechanism Cold Spring Harbor Symposia On Quantitative Biology. 65: 225-232. PMID 12760036 DOI: 10.1101/Sqb.2000.65.225  0.348
2000 Junop MS, Modesti M, Guarné A, Ghirlando R, Gellert M, Yang W. Crystal structure of the Xrcc4 DNA repair protein and implications for end joining Embo Journal. 19: 5962-5970. PMID 11080143 DOI: 10.1093/Emboj/19.22.5962  0.391
2000 Obmolova G, Ban C, Hsieh P, Yang W. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA Nature. 407: 703-710. PMID 11048710 DOI: 10.1038/35037509  0.381
1999 Kim DR, Dai Y, Mundy CL, Yang W, Oettinger MA. Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase. Genes & Development. 13: 3070-80. PMID 10601033 DOI: 10.1101/Gad.13.23.3070  0.321
1999 Ban C, Junop M, Yang W. Transformation of MutL by ATP binding and hydrolysis: A switch in DNA mismatch repair Cell. 97: 85-97. PMID 10199405 DOI: 10.1016/S0092-8674(00)80717-5  0.368
1998 Ban C, Yang W. Crystal structure and ATPase activity of MutL: Implications for DNA repair and mutagenesis Cell. 95: 541-552. PMID 9827806 DOI: 10.1016/S0092-8674(00)81621-9  0.368
1995 Yang W, Steitz TA. Recombining the structures of HIV integrase, RuvC and RNase H. Structure (London, England : 1993). 3: 131-4. PMID 7735828 DOI: 10.1016/S0969-2126(01)00142-3  0.404
1995 Yang W, Steitz TA. Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site. Cell. 82: 193-207. PMID 7628011 DOI: 10.1016/0092-8674(95)90307-0  0.381
1990 Yang W, Hendrickson WA, Kalman ET, Crouch RJ. Expression, purification, and crystallization of natural and selenomethionyl recombinant ribonuclease H from Escherichia coli. The Journal of Biological Chemistry. 265: 13553-9. PMID 2199440  0.415
1990 Yang W, Hendrickson WA, Crouch RJ, Satow Y. Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein. Science (New York, N.Y.). 249: 1398-405. PMID 2169648 DOI: 10.1126/Science.2169648  0.416
1989 Lustbader JW, Birken S, Pileggi NF, Kolks MA, Pollak S, Cuff ME, Yang W, Hendrickson WA, Canfield RE. Crystallization and characterization of human chorionic gonadotropin in chemically deglycosylated and enzymatically desialylated states. Biochemistry. 28: 9239-43. PMID 2611225 DOI: 10.1021/Bi00450A001  0.401
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