Kai Chen - Publications

California Institute of Technology, Pasadena, CA 
organic chemistry, organometallic chemistry, chemical biology

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chang Y, Liu Q, Zhou Z, Ding Y, Yang M, Xu W, Chen K, Zhang Q, Wang Z, Li H. Can Statin Treatment Reduce the Risk of Hepatocellular Carcinoma? A Systematic Review and Meta-Analysis. Technology in Cancer Research & Treatment. 19: 1533033820934881. PMID 32552476 DOI: 10.1177/1533033820934881  0.48
2020 Xu X, Li X, Li Z, Li Y, Chen K, Wu L, Fa Y, Xu Z, Xu Q. Effects of genetic background and environmental conditions on amylopectin chain-length distribution in a recombinant inbred line of an inter-subspecies rice cross. Journal of Agricultural and Food Chemistry. PMID 32551583 DOI: 10.1021/acs.jafc.0c02713  0.36
2020 Zhang T, Che Y, Chen K, Xu J, Xu Y, Wen T, Lu G, Liu X, Wang B, Xu X, Duh YS, Tang YL, Han J, Cao Y, Guan BO, et al. Anapole mediated giant photothermal nonlinearity in nanostructured silicon. Nature Communications. 11: 3027. PMID 32541692 DOI: 10.1038/s41467-020-16845-x  0.36
2020 Ren J, Chen L, Zhang N, Chen X, Zhao Q, Chen K, Li X, Ruschitzka F, Duru F, Song J. Plasma testosterone and arrhythmic events in male patients with arrhythmogenic right ventricular cardiomyopathy. Esc Heart Failure. PMID 32469163 DOI: 10.1002/ehf2.12704  0.36
2020 Tian Y, Chen K, Li X, Zheng Y, Chen F. Design of high-oleic tobacco (Nicotiana tabacum L.) seed oil by CRISPR-Cas9-mediated knockout of NtFAD2-2. Bmc Plant Biology. 20: 233. PMID 32450806 DOI: 10.1186/s12870-020-02441-0  0.36
2020 Wang D, Huang M, Gao D, Chen K, Xinxie, Xu W, Li X. Screening anti-TMV agents targeting tobacco mosaic virus helicase protein. Pesticide Biochemistry and Physiology. 166: 104449. PMID 32448412 DOI: 10.1016/j.pestbp.2019.07.017  0.36
2020 Wang W, Li X, Chen K, Yang H, Jialengbieke B, Hu X. Extraction optimization, characterization and the antioxidant activities in vitro and in vivo of polysaccharide from Pleurotus ferulae. International Journal of Biological Macromolecules. PMID 32446895 DOI: 10.1016/j.ijbiomac.2020.05.158  0.36
2020 Chen K, Liu Y, He J, Pavlos N, Wang C, Kenny J, Yuan J, Zhang Q, Xu J, He W. Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts. International Journal of Biological Sciences. 16: 1888-1900. PMID 32398957 DOI: 10.7150/ijbs.40917  0.48
2020 Chen K, Arnold FH. Engineering cytochrome P450s for enantioselective cyclopropenation of internal alkynes. Journal of the American Chemical Society. PMID 32223130 DOI: 10.1021/jacs.0c01313  1
2020 Wu L, Chen K, Xiao J, Xin J, Zhang L, Li X, Li L, Si J, Wang L, Ma K. Angiotensin II induces RAW264.7 macrophage polarization to the M1‑type through the connexin 43/NF‑κB pathway. Molecular Medicine Reports. PMID 32186758 DOI: 10.3892/mmr.2020.11023  0.36
2020 Tang W, Ke C, Chen K, Wu Z, Wu Y, Li X, Kang J. Magnetism manipulation of Con-adsorbed monolayer WS2 through charge injection. Journal of Physics. Condensed Matter : An Institute of Physics Journal. PMID 32155608 DOI: 10.1088/1361-648X/ab7e59  0.36
2020 Chen K, Chen L, Ouyang Y, Zhang L, Li X, Li L, Si J, Wang L, Ma K. Pirfenidone attenuates homocysteine‑induced apoptosis by regulating the connexin 43 pathway in H9C2 cells. International Journal of Molecular Medicine. PMID 32124965 DOI: 10.3892/ijmm.2020.4497  0.36
2020 Wang X, Li X, Huang B, Yang L, Chen K, Zhao D, Luo X, Wang Y. Downregulation of miR-33 Has Protective Effect Against Aβ₂₅₋₃₅-Induced Injury in SH-SH-SY5Y Cells. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 26: e921026. PMID 32119650 DOI: 10.12659/MSM.921026  0.36
2020 Wu XJ, Yan XT, Yang XM, Zhang Y, Wang HY, Luo H, Fang Q, Li H, Li XY, Chen K, Wang YL, Zhang ZZ, Song XM. GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice. Cytokine. 128: 155019. PMID 32018068 DOI: 10.1016/j.cyto.2020.155019  0.6
2020 Chen K, Zhao XL, Li LB, Huang LY, Tang Z, Luo J, Yang L, Qin AP, Hu F. miR-503/Apelin-12 mediates high glucose-induced microvascular endothelial cells injury via JNK and p38MAPK signaling pathway. Regenerative Therapy. 14: 111-118. PMID 31989001 DOI: 10.1016/j.reth.2019.12.002  0.36
2020 Liu Y, Wang Z, Ma C, Wei Z, Chen K, Wang C, Zhou C, Chen L, Zhang Q, Chen Z, He W, Xu J. Dracorhodin perchlorate inhibits osteoclastogenesis through repressing RANKL-stimulated NFATc1 activity. Journal of Cellular and Molecular Medicine. PMID 31965715 DOI: 10.1111/jcmm.15003  0.48
2019 Qiu YH, Ding SJ, Lin YJ, Chen K, Yang DJ, Ma S, Li X, Lin HQ, Wang J, Wang QQ. Growth of Au Hollow Stars and Harmonic Excitation Energy Transfer. Acs Nano. PMID 31841297 DOI: 10.1021/acsnano.9b07686  0.36
2019 He J, Li X, Wang Z, Bennett S, Chen K, Xiao Z, Zhan J, Chen S, Hou Y, Chen J, Wang S, Xu J, Lin D. Therapeutic Anabolic and Anticatabolic Benefits of Natural Chinese Medicines for the Treatment of Osteoporosis. Frontiers in Pharmacology. 10: 1344. PMID 31824310 DOI: 10.3389/fphar.2019.01344  0.36
2019 Zhou H, Li X, Shang Y, Chen K. Radical Scavenging Activity of Puerarin: A Theoretical Study. Antioxidants (Basel, Switzerland). 8. PMID 31779233 DOI: 10.3390/antiox8120590  0.36
2019 Qiu H, Ni W, Zhang H, Chen K, Yu J. Fabrication and evaluation of a regenerable HFO-doped agricultural waste for enhanced adsorption affinity towards phosphate. The Science of the Total Environment. 135493. PMID 31759714 DOI: 10.1016/j.scitotenv.2019.135493  0.56
2019 Qiu YH, Ding SJ, Nan F, Wang Q, Chen K, Hao ZH, Zhou L, Li X, Wang QQ. Manipulating the fluorescence of exciton-plasmon hybrids in the strong coupling regime with dual resonance enhancements. Nanoscale. PMID 31714554 DOI: 10.1039/c9nr05442a  0.36
2019 Li J, Van Valkenburgh J, Hong X, Conti PS, Zhang X, Chen K. Small molecules as theranostic agents in cancer immunology. Theranostics. 9: 7849-7871. PMID 31695804 DOI: 10.7150/thno.37218  0.52
2019 Wang D, Xie X, Gao D, Chen K, Chen Z, Jin L, Li X, Song B. Dufulin intervenes the viroplasmic proteins as the mechanism of action against southern rice black-streaked dwarf virus. Journal of Agricultural and Food Chemistry. PMID 31535865 DOI: 10.1021/acs.jafc.9b05793  0.36
2019 Ren R, Yu J, Zhang Y, Wang SF, Guo X, Shen M, Xu MD, Jiang M, Zhi Q, Chen K, Tao M, Wu MY, Gu DM, Li W. Inflammation Promotes Progression of Pancreatic Cancer Through WNT/β-Catenin Pathway-Dependent Manner. Pancreas. PMID 31404031 DOI: 10.1097/MPA.0000000000001386  0.56
2019 Liu Y, Wang C, Wang G, Sun Y, Deng Z, Chen L, Chen K, Tickner J, Kenny J, Song D, Zhang Q, Wang H, Chen Z, Zhou C, He W, et al. Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities. Theranostics. 9: 4648-4662. PMID 31367247 DOI: 10.7150/thno.35414  0.48
2019 Wang C, Li X, Jin L, Lu P, Dejoie C, Zhu W, Wang Z, Bi W, Dunin-Borkowski RE, Chen K, Jin M. Etching-Assisted Route to Heterophase Au Nanowires with Multiple Types of Active Surface Sites for Silane Oxidation. Nano Letters. PMID 31361961 DOI: 10.1021/acs.nanolett.9b02532  0.36
2019 Yang Q, Chen K, Zhang L, Feng L, Fu G, Jiang S, Bi S, Lin C, Zhou Y, Zhao H, Chen XL, Fu G, Xu B. Synthetic Lethality of Combined AT-101 with Idarubicin in Acute Myeloid Leukemia via Blockade of DNA Repair and Activation of Intrinsic Apoptotic Pathway. Cancer Letters. PMID 31301319 DOI: 10.1016/j.canlet.2019.07.003  0.52
2019 Li J, Hong X, Li G, Conti PS, Zhang X, Chen K. PET Imaging of Adenosine Receptors in Diseases. Current Topics in Medicinal Chemistry. PMID 31284861 DOI: 10.2174/1568026619666190708163407  0.52
2019 Chen K, Zheng Y, Wei JA, Ouyang H, Huang X, Zhang F, Lai CSW, Ren C, So KF, Zhang L. Exercise training improves motor skill learning via selective activation of mTOR. Science Advances. 5: eaaw1888. PMID 31281888 DOI: 10.1126/sciadv.aaw1888  0.68
2019 Zhu N, Wang J, Yu L, Zhang Q, Chen K, Liu B. Modulation of Growth Performance and Intestinal Microbiota in Chickens Fed Plant Extracts or Virginiamycin. Frontiers in Microbiology. 10: 1333. PMID 31275268 DOI: 10.3389/fmicb.2019.01333  0.48
2019 Li N, Li X, Chen K, Dong H, Kagami H. Characterization of spontaneous spheroids from oral mucosa-derived cells and their direct comparison with spheroids from skin-derived cells. Stem Cell Research & Therapy. 10: 184. PMID 31234925 DOI: 10.1186/s13287-019-1283-0  0.36
2019 Chen K, Li X, Li N, Dong H, Zhang Y, Yoshizawa M, Kagami H. Spontaneously Formed Spheroids from Mouse Compact Bone-Derived Cells Retain Highly Potent Stem Cells with Enhanced Differentiation Capability. Stem Cells International. 2019: 8469012. PMID 31191686 DOI: 10.1155/2019/8469012  0.36
2019 Chen K, Li X, Song G, Zhou T, Long Y, Li Q, Zhong S, Cui Z. Deficiency in the membrane protein Tmbim3a/Grinaa initiates cold-induced ER stress and cell death by activating an intrinsic apoptotic pathway in zebrafish. The Journal of Biological Chemistry. PMID 31171717 DOI: 10.1074/jbc.RA119.007813  0.36
2019 Bi S, Chen K, Feng L, Fu G, Yang Q, Deng M, Zhao H, Li Z, Yu L, Fang Z, Xu B. Napabucasin (BBI608) eliminate AML cells in vitro and in vivo via inhibition of Stat3 pathway and induction of DNA damage. European Journal of Pharmacology. PMID 31085238 DOI: 10.1016/j.ejphar.2019.05.020  0.52
2019 Brandenberg OF, Chen K, Arnold FH. Directed Evolution of a Cytochrome P450 Carbene Transferase for Selective Functionalization of Cyclic Compounds. Journal of the American Chemical Society. PMID 31070908 DOI: 10.1021/jacs.9b02931  1
2019 Gao D, Wang D, Chen K, Huang M, Xie X, Li X. Activation of biochemical factors in CMV-infected tobacco by ningnanmycin. Pesticide Biochemistry and Physiology. 156: 116-122. PMID 31027570 DOI: 10.1016/j.pestbp.2019.02.012  0.36
2019 Chen L, Song J, Chen X, Chen K, Ren J, Zhang N, Rao M, Hu Z, Zhang Y, Gu M, Zhao H, Tang H, Yang Z, Hu S. A novel genotype-based clinicopathology classification of arrhythmogenic cardiomyopathy provides novel insights into disease progression. European Heart Journal. PMID 30945739 DOI: 10.1093/eurheartj/ehz172  0.52
2019 Chen K, Huang X, Zhang SQ, Zhou AZ, Kan SBJ, Hong X, Arnold FH. Engineered Cytochrome -Catalyzed Lactone-Carbene B-H Insertion. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 30: 378-382. PMID 30930550 DOI: 10.1055/s-0037-1611662  1
2019 Chen K, Deng L, She H, Hu F, Li T. MR neurography showed brachial plexus abnormalities in syringomyelia with shoulder Charcot arthropathy: a case report. British Journal of Neurosurgery. 1-3. PMID 30892961 DOI: 10.1080/02688697.2019.1590526  0.36
2019 Chen K, Zhang Q, Wang CC, Liu ZX, Jiang YJ, Zhai LY, Zheng TQ, Xu JL, Li ZK. Genetic dissection of seedling vigour in a diverse panel from the 3,000 Rice (Oryza sativa L.) Genome Project. Scientific Reports. 9: 4804. PMID 30886215 DOI: 10.1038/s41598-019-41217-x  0.48
2019 Li X, Wang Y, Chen K, Gao D, Wang D, Xue W. Cucumber mosaic virus coat protein: The potential target of 1, 4-pentadien-3-one derivatives. Pesticide Biochemistry and Physiology. 155: 45-50. PMID 30857626 DOI: 10.1016/j.pestbp.2019.01.004  0.36
2019 Lin J, Qi W, Liu Z, Chen K, Li X, Yan Y, Xu X, Xue X, Yang Y, Pan X. An arthroscopic technique for full-thickness rotator cuff repair by transposition of the long head of biceps. Orthopaedics & Traumatology, Surgery & Research : Otsr. PMID 30765311 DOI: 10.1016/j.otsr.2018.07.027  0.36
2018 Li X, Wang X, Wu Y, Sun S, Chen K, Lu Y, Wang Q, Zhao Z. Plasma and cerebrospinal fluid population pharmacokinetic modeling and simulation of meropenem after intravenous and intrathecal administration in postoperative neurosurgical patients. Diagnostic Microbiology and Infectious Disease. PMID 30638947 DOI: 10.1016/j.diagmicrobio.2018.08.003  0.36
2018 Zhang RK, Chen K, Huang X, Wohlschlager L, Renata H, Arnold FH. Enzymatic assembly of carbon-carbon bonds via iron-catalysed sp C-H functionalization. Nature. PMID 30568304 DOI: 10.1038/s41586-018-0808-5  1
2018 Lin J, Qi W, Chen K, Yan Y, Li X, Feng Z, Pan X. Downregulating STAT1/caspase-3 signaling with fludarabine to alleviate progression in a rat model of steroid-induced avascular necrosis of the femoral head. Journal of Biochemical and Molecular Toxicology. e22265. PMID 30506661 DOI: 10.1002/jbt.22265  0.36
2018 Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, et al. VCAM-1 macrophages guide the homing of HSPCs to a vascular niche. Nature. PMID 30455424 DOI: 10.1038/s41586-018-0709-7  0.36
2018 Chen K, Zhang SQ, Brandenberg OF, Hong X, Arnold FH. Alternate heme ligation steers activity and selectivity in engineered cytochrome P450-catalyzed carbene transfer reactions. Journal of the American Chemical Society. PMID 30372623 DOI: 10.1021/jacs.8b09613  1
2018 Li X, Li N, Chen K, Nagasawa S, Yoshizawa M, Kagami H. Around 90° contact angle of dish surface is a key factor in achieving spontaneous spheroid formation. Tissue Engineering. Part C, Methods. PMID 30234440 DOI: 10.1089/ten.TEC.2018.0188  0.36
2018 Lin J, Li X, Qi W, Yan Y, Chen K, Xue X, Xu X, Feng Z, Pan X. Isofraxidin inhibits interleukin-1β induced inflammatory response in human osteoarthritis chondrocytes. International Immunopharmacology. 64: 238-245. PMID 30205322 DOI: 10.1016/j.intimp.2018.09.003  0.36
2018 Li J, Li Z, Jiang P, Peng M, Zhang X, Chen K, Liu H, Bi H, Liu X, Li X. Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis. Journal of Experimental & Clinical Cancer Research : Cr. 37: 177. PMID 30064461 DOI: 10.1186/s13046-018-0822-3  0.36
2018 Chen Y, Zhang Y, Yang W, Li X, Zhu L, Chen K, Chen X. Accuracy of a nomogram to predict the survival benefit of surgical axillary staging in T1 breast cancer patients. Medicine. 97: e11273. PMID 29953003 DOI: 10.1097/MD.0000000000011273  0.36
2018 Deng M, Shi Y, Chen K, Zhao H, Wang Y, Xie S, Zhao J, Luo Y, Fang Z, Fan Y, Xu B. CS2164 exerts an antitumor effect against human Non-Hodgkin's lymphomas in vitro and in vivo. Experimental Cell Research. PMID 29864401 DOI: 10.1016/j.yexcr.2018.05.038  0.52
2018 Li Z, Xia Y, Chen K, Zhao H, Liu Y. Maintenance of the Maxillomandibular Position with Digital Workflow in Oral Rehabilitation: A Technical Note. The International Journal of Prosthodontics. 31: 280-282. PMID 29723325  0.52
2018 Li Z, Yanfang W, Li J, Jiang P, Peng T, Chen K, Zhao X, Zhang Y, Zhen P, Zhu J, Li X. Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338/MACC1/MET pathway in pancreatic cancer. Cancer Letters. PMID 29709702 DOI: 10.1016/j.canlet.2018.04.035  0.36
2018 Zhang Y, Xu Y, Chen S, Lu H, Chen K, Cao Y, Miroshnichenko AE, Gu M, Li X. Ultra-Broadband Directional Scattering by Colloidally Lithographed High-Index Mie Resonant Oligomers and Their Energy-Harvesting Applications. Acs Applied Materials & Interfaces. PMID 29682955 DOI: 10.1021/acsami.8b03718  0.36
2018 Li Z, Jiang P, Li J, Peng M, Zhao X, Zhang X, Chen K, Zhang Y, Liu H, Gan L, Bi H, Zhen P, Zhu J, Li X. Tumor-derived exosomal lnc-Sox2ot promotes EMT and stemness by acting as a ceRNA in pancreatic ductal adenocarcinoma. Oncogene. PMID 29643475 DOI: 10.1038/s41388-018-0237-9  0.36
2018 Knight AM, Kan SBJ, Lewis RD, Brandenberg OF, Chen K, Arnold FH. Diverse Engineered Heme Proteins Enable Stereodivergent Cyclopropanation of Unactivated Alkenes. Acs Central Science. 4: 372-377. PMID 29632883 DOI: 10.1021/acscentsci.7b00548  1
2018 Chen K, Huang X, Kan SBJ, Zhang RK, Arnold FH. Enzymatic construction of highly strained carbocycles. Science (New York, N.Y.). 360: 71-75. PMID 29622650 DOI: 10.1126/science.aar4239  1
2018 Lin Y, Zhao F, Prasad SKK, Chen JD, Cai W, Zhang Q, Chen K, Wu Y, Ma W, Gao F, Tang JX, Wang C, You W, Hodgkiss JM, Zhan X. Balanced Partnership between Donor and Acceptor Components in Nonfullerene Organic Solar Cells with >12% Efficiency. Advanced Materials (Deerfield Beach, Fla.). PMID 29513373 DOI: 10.1002/adma.201706363  0.48
2018 Cheng F, Xu K, Liu L, Yao C, Xu P, Zhou G, Li D, Li X, Chen K, Zou Z, Tan G. New neolignans from Selaginella picta and their protective effect on HT-22 cells. Fitoterapia. PMID 29421239 DOI: 10.1016/j.fitote.2018.02.008  0.36
2018 Ding HW, Deng CL, Li DD, Liu DD, Chai SM, Wang W, Zhang Y, Chen K, Li X, Wang J, Song SJ, Song HR. Design, synthesis and biological evaluation of novel 4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα. European Journal of Medicinal Chemistry. 146: 460-470. PMID 29407971 DOI: 10.1016/j.ejmech.2018.01.081  0.36
2017 Wu B, Fu SH, Tang H, Chen K, Zhang Q, Peng AH, Ye HY, Cheng XJ, Lian M, Wang ZL, Chen LJ. Design, synthesis and antibacterial evaluation of honokiol derivatives. Bioorganic & Medicinal Chemistry Letters. PMID 29402745 DOI: 10.1016/j.bmcl.2017.06.022  0.48
2017 Wu XJ, Liang H, Zhang Y, Yang XM, Wang HY, Li H, Li XY, Chen K, Wang YL, Li JG, Zhang ZZ, Song XM. Muramyl Dipeptide Enhances Thermal Injury-Induced Autophagy and Inflammatory Cytokine Response of Lungs via Activation of Nod2/Rick Signaling Pathway in Rats. Shock (Augusta, Ga.). PMID 29215417 DOI: 10.1097/SHK.0000000000001077  0.6
2017 Kan SBJ, Huang X, Gumulya Y, Chen K, Arnold FH. Genetically programmed chiral organoborane synthesis. Nature. 552: 132-136. PMID 29186119 DOI: 10.1038/nature24996  1
2017 Huang X, He J, Yan X, Hong Q, Chen K, He Q, Zhang L, Liu X, Chuang S, Li S, Jiang J. Microbial catabolism of chemical herbicides: Microbial resources, metabolic pathways and catabolic genes. Pesticide Biochemistry and Physiology. 143: 272-297. PMID 29183604 DOI: 10.1016/j.pestbp.2016.11.010  0.68
2017 Lu M, Zhang Q, Chen K, Xu W, Xiang X, Xia S. The regulatory effect of oxymatrine on the TLR4/MyD88/NF-κB signaling pathway in lipopolysaccharide-induced MS1 cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 36: 153-159. PMID 29157809 DOI: 10.1016/j.phymed.2017.10.001  0.48
2017 Wu G, Li Z, Jiang P, Zhang X, Xu Y, Chen K, Li X. MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1. Oncotarget. 8: 82854-82871. PMID 29137308 DOI: 10.18632/oncotarget.20692  0.36
2017 Li X, Liu C, Jiang B, Chen K, Li W, Wang H. The antidepressant-like effects of sinomenine in mice: a behavioral and neurobiological characterization. Behavioural Pharmacology. PMID 29035920 DOI: 10.1097/FBP.0000000000000350  0.36
2017 Liu Y, Zhang Y, Chen K, Quan X, Fan X, Su Y, Chen S, Zhao H, Zhang Y, Yu H, Hoffmann MR. Selective electrochemical reduction of CO2 to ethanol on B and N codoped nanodiamond. Angewandte Chemie (International Ed. in English). PMID 28914470 DOI: 10.1002/anie.201706311  0.52
2017 Li X, Sun S, Ling X, Chen K, Wang Q, Zhao Z. Plasma and cerebrospinal fluid population pharmacokinetics of vancomycin in postoperative neurosurgical patients after combined intravenous and intraventricular administration. European Journal of Clinical Pharmacology. PMID 28849406 DOI: 10.1007/s00228-017-2313-4  0.36
2017 Chen K, He D, Zhao H. Violation of the virial theorem and generalized equipartition theorem for logarithmic oscillators serving as a thermostat. Scientific Reports. 7: 3460. PMID 28615728 DOI: 10.1038/s41598-017-03694-w  0.52
2017 Ling PX, Fang SL, Yin XS, Zhang Q, Chen K, Shi BF. Palladium-catalyzed sequential monoarylation/amidation of C(sp(3))-H bonds: stereoselective synthesis of α-amino-β-lactams and anti-α,β-diamino acid. Chemical Communications (Cambridge, England). PMID 28555232 DOI: 10.1039/c7cc02426f  0.92
2017 Chen K, Li X, Zhu H, Gong Q, Luo K. Endocytosis of Nanoscale Systems for Cancer Treatments. Current Medicinal Chemistry. PMID 28462706 DOI: 10.2174/0929867324666170428153056  0.36
2017 Zhang Q, Xu L, Zhang Y, Wang T, Zou X, Zhu Y, Zhao Y, Li C, Chen K, Sun Y, Sun J, Zhao Q, Wang Q. A novel ViewRNA in situ hybridization method for the detection of the dynamic distribution of Classical Swine Fever Virus RNA in PK15 cells. Virology Journal. 14: 81. PMID 28420390 DOI: 10.1186/s12985-017-0734-4  0.48
2017 Yu J, Chen K, Yang B, Zhang F, Ju W, Chen H, Yang G, Li M, Wang B, Gu K, Ouyang F, Ho SY, Po S, Chen M. Peri-mitral atrial flutter: personalized ablation strategy based on arrhythmogenic substrate. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 28340110 DOI: 10.1093/europace/euw431  0.56
2017 Zhang Q, Pei HY, Chen K, Tang H, Wu B, Tang MH, Peng AH, Ye HY, Chen LJ. Separation of caffeoylquinic acids and flavonoids from Asteris souliei by high-performance counter-current chromatography and their anti-inflammatory activity in vitro. Journal of Separation Science. PMID 28332768 DOI: 10.1002/jssc.201601422  0.48
2017 Ling PX, Chen K, Shi BF. Palladium-catalyzed interannular meta-C-H arylation. Chemical Communications (Cambridge, England). PMID 28144666 DOI: 10.1039/c7cc00110j  0.92
2017 Mei S, Wang J, Zhu L, Chen R, Li X, Chen K, Chen G, Zhou J, Wang Q, Zhao Z. An UPLC-MS/MS method for analysis of vancomycin in human cerebrospinal fluid and comparison with the chemiluminescence immunoassay. Biomedical Chromatography : Bmc. PMID 28139829 DOI: 10.1002/bmc.3939  0.36
2017 Xu MD, Liu SL, Feng YZ, Liu Q, Shen M, Zhi Q, Liu Z, Gu DM, Yu J, Shou LM, Gong FR, Zhu Q, Duan W, Chen K, Zhang J, et al. Genomic characteristics of pancreatic squamous cell carcinoma, an investigation by using high throughput sequencing after in-solution hybrid capture. Oncotarget. PMID 28099906 DOI: 10.18632/oncotarget.14678  0.56
2016 Kan SB, Lewis RD, Chen K, Arnold FH. Directed evolution of cytochrome c for carbon-silicon bond formation: Bringing silicon to life. Science (New York, N.Y.). 354: 1048-1051. PMID 27885032 DOI: 10.1126/science.aah6219  1
2016 Zhang X, Jiang P, Shuai L, Chen K, Li Z, Zhang Y, Jiang Y, Li X. miR-589-5p inhibits MAP3K8 and suppresses CD90(+) cancer stem cells in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 35: 176. PMID 27835990 DOI: 10.1186/s13046-016-0452-6  0.36
2016 Liao G, Yin XS, Chen K, Zhang Q, Zhang SQ, Shi BF. Stereoselective alkoxycarbonylation of unactivated C(sp3)-H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis. Nature Communications. 7: 12901. PMID 27678161 DOI: 10.1038/ncomms12901  0.92
2016 Liu YJ, Liu YH, Zhang ZZ, Yan SY, Chen K, Shi BF. Divergent and Stereoselective Synthesis of β-Silyl-α-Amino Acids through Palladium-Catalyzed Intermolecular Silylation of Unactivated Primary and Secondary C-H Bonds. Angewandte Chemie (International Ed. in English). PMID 27678130 DOI: 10.1002/anie.201607766  0.92
2016 He J, Cai X, Chen K, Li Y, Zhang K, Jin Z, Meng F, Liu N, Wang X, Kong L, Huang X, Liu J. Performance of a novelly-defined zirconium metal-organic frameworks adsorption membrane in fluoride removal. Journal of Colloid and Interface Science. 484: 162-172. PMID 27610471 DOI: 10.1016/j.jcis.2016.08.074  0.68
2016 Tang H, Pei HY, Wang TJ, Chen K, Wu B, Yang QN, Zhang Q, Yang JH, Wang XY, Tang MH, Peng AH, Ye HY, Chen LJ. Flavonoids and biphenylneolignans with anti-inflammatory activity from the stems of Millettia griffithii. Bioorganic & Medicinal Chemistry Letters. PMID 27542306 DOI: 10.1016/j.bmcl.2016.08.009  0.48
2016 Li Z, Zhao X, Jiang P, Xiao S, Wu G, Chen K, Zhang X, Liu H, Han X, Wang S, Li X. HBV is a risk factor for poor patient prognosis after curative resection of hepatocellular carcinoma: A retrospective case-control study. Medicine. 95: e4224. PMID 27495026 DOI: 10.1097/MD.0000000000004224  0.36
2016 Sheng Z, Chen K, Li X. [Advances in the biosynthesis of spinosad - A review]. Wei Sheng Wu Xue Bao. 56: 397-405. PMID 27382783  0.36
2016 Huang X, Chen K, Qi M, Li Y, Hou Y, Wang Y, Zhao Q, Luo X, Xu Q. Nanostructured grating patterns over a large area fabricated by optically directed assembly. Nanoscale. PMID 27341650 DOI: 10.1039/c6nr01310d  0.68
2016 Liu W, Deng Y, Zhou Y, Chen H, Dong Y, Wang N, Li X, Jameel A, Yang H, Zhang M, Chen K, Wang F, Li H. Normalization for Relative Quantification of mRNA and microRNA in Soybean Exposed to Various Abiotic Stresses. Plos One. 11: e0155606. PMID 27176476 DOI: 10.1371/journal.pone.0155606  0.36
2016 Lyu J, Chen K, Tang Z, Chen Y, Li M, Zhang Q. A comparison of three different surgical procedures in the treatment of type A thoracolumbar fractures: a randomized controlled trial. International Orthopaedics. PMID 26907876 DOI: 10.1007/s00264-016-3129-z  0.48
2016 Liang R, Chen K, Zhang Q, Zhang J, Jiang H, Zhu S. Rapid Access to 2-Methylene Tetrahydrofurans and γ-Lactones: A Tandem Four-Step Process. Angewandte Chemie (International Ed. in English). PMID 26797825 DOI: 10.1002/anie.201511133  0.48
2016 Li X, Kong S, Yin Y, Li L, Yuan L, Li Q, Xiao H, Chen K. Polycyclic aromatic hydrocarbons (PAHs) in atmospheric PM2.5 around 2013 Asian Youth Games period in Nanjing Atmospheric Research. 174: 85-96. DOI: 10.1016/j.atmosres.2016.01.010  0.36
2016 Wu X, Yan C, Meng Z, Chen K, Song S, Yang Z, Yu J. Numerical analysis of the passive heat removal system for molten salt reactor at steady state Applied Thermal Engineering. 102: 1337-1344. DOI: 10.1016/j.applthermaleng.2016.03.176  0.56
2015 Ling PX, Fang SL, Yin XS, Chen K, Sun BZ, Shi BF. Palladium-Catalyzed Arylation of Unactivated γ-Methylene C(sp(3) )H and δ-CH Bonds with an Oxazoline-Carboxylate Auxiliary. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 17503-7. PMID 26769628 DOI: 10.1002/chem.201502621  0.92
2015 Chen K, Li X, Zhang SQ, Shi BF. Synthesis of chiral α-hydroxy acids via palladium-catalyzed C(sp(3))-H alkylation of lactic acid. Chemical Communications (Cambridge, England). PMID 26679740 DOI: 10.1039/c5cc07879b  0.92
2015 Ambrosi CM, Boyle PM, Chen K, Trayanova NA, Entcheva E. Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability. Scientific Reports. 5: 17350. PMID 26621212 DOI: 10.1038/srep17350  0.56
2015 Liu JP, Chen KJ. Methodology guideline for clinical studies investigating traditional Chinese medicine and integrative medicine: executive summary. Complementary Therapies in Medicine. 23: 751-6. PMID 26615617 DOI: 10.1016/j.ctim.2015.08.001  0.36
2015 Yu J, Chen K, Lucero RV, Ambrosi CM, Entcheva E. Cardiac Optogenetics: Enhancement by All-trans-Retinal. Scientific Reports. 5: 16542. PMID 26568132 DOI: 10.1038/srep16542  0.56
2015 Jiang X, Ma Z, Xu J, Chen K, Xu L, Li W, Huang X, Feng D. a-SiNx:H-based ultra-low power resistive random access memory with tunable Si dangling bond conduction paths. Scientific Reports. 5: 15762. PMID 26508086 DOI: 10.1038/srep15762  0.68
2015 Chen K, Xu X, Guo JW, Zhang X, Han S, Wang R, Li X, Zhang J. Enhanced Intracellular Delivery and Tissue Retention of Nanoparticles by Mussel-Inspired Surface Chemistry. Biomacromolecules. PMID 26418329 DOI: 10.1021/acs.biomac.5b01056  0.36
2015 Cheng M, Chen K, Guo S, Huang X, He J, Li S, Jiang J. PbaR, an IclR-Family Transcriptional Activator for the Regulation of the 3-Phenoxybenzoate 1',2' -Dioxygenase Gene Cluster in Sphingobium wenxiniae JZ-1T. Applied and Environmental Microbiology. PMID 26386050 DOI: 10.1128/AEM.02122-15  0.68
2015 Zhang D, Wei Y, Chen K, Gong H, Han S, Guo J, Li X, Zhang J. Engineering of Biocompatible pH-Responsive Nanovehicles from Acetalated Cyclodextrins as Effective Delivery Systems for Tumor Therapy. Journal of Biomedical Nanotechnology. 11: 923-41. PMID 26353583  0.36
2015 Wang Y, Bu J, Zhang Q, Chen K, Zhang J, Bao X. Expression pattern of aquaporins in patients with primary nephrotic syndrome with edema. Molecular Medicine Reports. PMID 26261083 DOI: 10.3892/mmr.2015.4209  0.48
2015 Li CM, Chen K, Chen YN, Zhang Q, Chen YA, Pan JW. Genuine High-Order Einstein-Podolsky-Rosen Steering. Physical Review Letters. 115: 010402. PMID 26182083  0.48
2015 Xu JL, Wang Y, Zhang F, Wu Y, Zheng TQ, Wang YH, Zhao XQ, Cui YR, Chen K, Zhang Q, Lin HX, Li JY, Li ZK. SS1 (NAL1)- and SS2-Mediated Genetic Networks Underlying Source-Sink and Yield Traits in Rice (Oryza sativa L.). Plos One. 10: e0132060. PMID 26162098 DOI: 10.1371/journal.pone.0132060  0.48
2015 Zhu S, Zhang Q, Chen K, Jiang H. Synergistic Catalysis: Metal/Proton-Catalyzed Cyclization of Alkynones Toward Bicyclo[3.n.1]alkanones. Angewandte Chemie (International Ed. in English). PMID 26138939 DOI: 10.1002/anie.201504964  0.48
2015 Rao WH, Zhan BB, Chen K, Ling PX, Zhang ZZ, Shi BF. Pd(II)-Catalyzed Direct Sulfonylation of Unactivated C(sp(3))-H Bonds with Sodium Sulfinates. Organic Letters. PMID 26110825 DOI: 10.1021/acs.orglett.5b01634  0.92
2015 Zhang Q, Yin XS, Chen K, Zhang SQ, Shi BF. Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp(3))-H Bonds: Scope and Mechanistic Studies. Journal of the American Chemical Society. 137: 8219-26. PMID 26067591 DOI: 10.1021/jacs.5b03989  0.92
2015 Yang Z, Chen X, Zhang Q, Cai B, Chen K, Chen Z, Bai Y, Shi Z, Li M. Dysregulated COL3A1 and RPL8, RPS16, RPS23 in Disc Degeneration Revealed by Bioinformatics Methods. Spine. PMID 25893343 DOI: 10.1097/BRS.0000000000000939  0.48
2015 He XH, Li QW, Wang YL, Zhang ZZ, Ke JJ, Yan XT, Chen K. Transduced PEP-1-heme oxygenase-1 fusion protein reduces remote organ injury induced by intestinal ischemia/reperfusion. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 21: 1057-65. PMID 25863938 DOI: 10.12659/MSM.893924  0.6
2015 Cao X, Chen K, He D. Magnon Hall effect on the Lieb lattice. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 27: 166003. PMID 25817818 DOI: 10.1088/0953-8984/27/16/166003  0.52
2015 Chen K, Zhang SQ, Jiang HZ, Xu JW, Shi BF. Practical synthesis of anti-β-hydroxy-α-amino acids by Pd(II) -catalyzed sequential C(sp(3) )-H functionalization. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 3264-70. PMID 25589007 DOI: 10.1002/chem.201405942  0.92
2014 Chen K, Zhang SQ, Xu JW, Hu F, Shi BF. A general and practical palladium-catalyzed monoarylation of β-methyl C(sp³)-H of alanine. Chemical Communications (Cambridge, England). 50: 13924-7. PMID 25259442 DOI: 10.1039/c4cc06652a  0.92
2014 Chen K, Shi BF. Sulfonamide-promoted palladium(II)-catalyzed alkylation of unactivated methylene C(sp3)-H bonds with alkyl iodides. Angewandte Chemie (International Ed. in English). 53: 11950-4. PMID 25213367 DOI: 10.1002/anie.201407848  0.92
2014 Zhang Q, Chen K, Shi BF. Recent progress in the synthesis of functionalized β-lactams through transition-metal-catalyzed C(sp3)-H amidation Synlett. 25: 1941-1945. DOI: 10.1055/s-0033-1338645  0.92
2013 Zhang Q, Chen K, Rao W, Zhang Y, Chen FJ, Shi BF. Stereoselective synthesis of chiral α-amino-β-lactams through palladium(II)-catalyzed sequential monoarylation/amidation of C(sp(3) )-H bonds. Angewandte Chemie (International Ed. in English). 52: 13588-92. PMID 24174011 DOI: 10.1002/anie.201306625  0.92
1993 Chen K, Arnold FH. Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide. Proceedings of the National Academy of Sciences of the United States of America. 90: 5618-22. PMID 8516309  1
1992 Economou C, Chen K, Arnold FH. Random mutagenesis to enhance the activity of subtilisin in organic solvents: Characterization of Q103R subtilisin E. Biotechnology and Bioengineering. 39: 658-62. PMID 18600995 DOI: 10.1002/bit.260390610  1
1992 Martinez P, Van Dam ME, Robinson AC, Chen K, Arnold FH. Stabilization of substilisin E in organic solvents by site-directed mutagenesis. Biotechnology and Bioengineering. 39: 141-7. PMID 18600924 DOI: 10.1002/bit.260390204  1
1991 Chen KQ, Arnold FH. Enzyme engineering for nonaqueous solvents: random mutagenesis to enhance activity of subtilisin E in polar organic media. Bio/Technology (Nature Publishing Company). 9: 1073-7. PMID 1367624  1
1991 Chen KQ, Robinson AC, Van Dam ME, Martinez P, Economou C, Arnold FH. Enzyme engineering for nonaqueous solvents. II. Additive effects of mutations on the stability and activity of subtilisin E in polar organic media. Biotechnology Progress. 7: 125-9. PMID 1367168 DOI: 10.1021/bp00008a007  1
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