Year |
Citation |
Score |
2021 |
Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, Cortes LBG, Ferrante T, Bening SC, Wong F, Gruber C, Bakerlee CW, Lambert G, Walker GC, Dwyer DJ, et al. Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality. Cell Chemical Biology. PMID 34990601 DOI: 10.1016/j.chembiol.2021.12.010 |
0.406 |
|
2018 |
Mack SG, Turner RL, Dwyer DJ. Achieving a Predictive Understanding of Antimicrobial Stress Physiology through Systems Biology. Trends in Microbiology. PMID 29530606 DOI: 10.1016/J.Tim.2018.02.004 |
0.392 |
|
2016 |
Buckner MM, Blair JM, La Ragione RM, Newcombe J, Dwyer DJ, Ivens A, Piddock LJ. Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology. Mbio. 7. PMID 27879336 DOI: 10.1128/Mbio.01916-16 |
0.391 |
|
2016 |
Oberhardt MA, Zarecki R, Reshef L, Xia F, Duran-Frigola M, Schreiber R, Henry CS, Ben-Tal N, Dwyer DJ, Gophna U, Ruppin E. Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5'-Phosphate Production in E. coli. Plos Computational Biology. 12: e1004705. PMID 26821166 DOI: 10.1371/Journal.Pcbi.1004705 |
0.347 |
|
2015 |
Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS, Collins JJ. Antibiotic efficacy is linked to bacterial cellular respiration. Proceedings of the National Academy of Sciences of the United States of America. PMID 26100898 DOI: 10.1073/Pnas.1509743112 |
0.678 |
|
2015 |
Dwyer DJ, Collins JJ, Walker GC. Unraveling the physiological complexities of antibiotic lethality. Annual Review of Pharmacology and Toxicology. 55: 313-32. PMID 25251995 DOI: 10.1146/Annurev-Pharmtox-010814-124712 |
0.562 |
|
2015 |
Dwyer DJ. To kill a bacterium - A complex 80-year-old story Biochemist. 37: 4-10. |
0.398 |
|
2014 |
Dwyer DJ, Belenky PA, Yang JH, MacDonald IC, Martell JD, Takahashi N, Chan CT, Lobritz MA, Braff D, Schwarz EG, Ye JD, Pati M, Vercruysse M, Ralifo PS, Allison KR, et al. Antibiotics induce redox-related physiological alterations as part of their lethality. Proceedings of the National Academy of Sciences of the United States of America. 111: E2100-9. PMID 24803433 DOI: 10.1073/Pnas.1401876111 |
0.771 |
|
2013 |
Dwyer DJ, Winkler JA. Identification and characterization of programmed cell death markers in bacterial models. Methods in Molecular Biology (Clifton, N.J.). 1004: 145-59. PMID 23733575 DOI: 10.1007/978-1-62703-383-1_11 |
0.71 |
|
2012 |
Dwyer DJ, Camacho DM, Kohanski MA, Callura JM, Collins JJ. Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. Molecular Cell. 46: 561-72. PMID 22633370 DOI: 10.1016/J.Molcel.2012.04.027 |
0.703 |
|
2010 |
Callura JM, Dwyer DJ, Isaacs FJ, Cantor CR, Collins JJ. Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proceedings of the National Academy of Sciences of the United States of America. 107: 15898-903. PMID 20713708 DOI: 10.1073/Pnas.1009747107 |
0.688 |
|
2010 |
Kohanski MA, Dwyer DJ, Collins JJ. How antibiotics kill bacteria: from targets to networks. Nature Reviews. Microbiology. 8: 423-35. PMID 20440275 DOI: 10.1038/Nrmicro2333 |
0.701 |
|
2009 |
Dwyer DJ, Kohanski MA, Collins JJ. Role of reactive oxygen species in antibiotic action and resistance. Current Opinion in Microbiology. 12: 482-9. PMID 19647477 DOI: 10.1016/J.Mib.2009.06.018 |
0.693 |
|
2008 |
Dwyer DJ, Kohanski MA, Collins JJ. Networking opportunities for bacteria. Cell. 135: 1153-6. PMID 19109881 DOI: 10.1016/J.Cell.2008.12.016 |
0.628 |
|
2008 |
Kohanski MA, Dwyer DJ, Wierzbowski J, Cottarel G, Collins JJ. Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell. 135: 679-90. PMID 19013277 DOI: 10.1016/J.Cell.2008.09.038 |
0.719 |
|
2007 |
Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ. A common mechanism of cellular death induced by bactericidal antibiotics. Cell. 130: 797-810. PMID 17803904 DOI: 10.1016/J.Cell.2007.06.049 |
0.738 |
|
2007 |
Dwyer DJ, Kohanski MA, Hayete B, Collins JJ. Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Molecular Systems Biology. 3: 91. PMID 17353933 DOI: 10.1038/Msb4100135 |
0.742 |
|
2006 |
Isaacs FJ, Dwyer DJ, Collins JJ. RNA synthetic biology. Nature Biotechnology. 24: 545-54. PMID 16680139 DOI: 10.1038/Nbt1208 |
0.677 |
|
2004 |
Isaacs FJ, Dwyer DJ, Ding C, Pervouchine DD, Cantor CR, Collins JJ. Engineered riboregulators enable post-transcriptional control of gene expression. Nature Biotechnology. 22: 841-7. PMID 15208640 DOI: 10.1038/Nbt986 |
0.667 |
|
1999 |
Rodriguez A, Armstrong M, Dwyer D, Flemington E. Genetic dissection of cell growth arrest functions mediated by the Epstein-Barr virus lytic gene product, Zta Journal of Virology. 73: 9029-9038. PMID 10516009 DOI: 10.1128/Jvi.73.11.9029-9038.1999 |
0.341 |
|
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