Philine A. Wangemann - Publications

Affiliations: 
Department of Anatomy and Physiology Kansas State University, Manhattan, KS, United States 
Area:
Animal Physiology Biology, Molecular Biology

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jeong J, Kim JY, Hong H, Wangemann P, Marcus DC, Jung J, Choi JY, Kim SH. P2RX2 and P2RX4 receptors mediate cation absorption in transitional cells and supporting cells of the utricular macula. Hearing Research. 386: 107860. PMID 31869657 DOI: 10.1016/J.Heares.2019.107860  0.332
2019 Kim MA, Kim SH, Ryu N, Ma JH, Kim YR, Jung J, Hsu CJ, Choi JY, Lee KY, Wangemann P, Bok J, Kim UK. Gene therapy for hereditary hearing loss by SLC26A4 mutations in mice reveals distinct functional roles of pendrin in normal hearing. Theranostics. 9: 7184-7199. PMID 31695761 DOI: 10.7150/Thno.38032  0.402
2018 Nakanishi H, Kurima K, Pan B, Wangemann P, Fitzgerald TS, Géléoc GS, Holt JR, Griffith AJ. Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function. Scientific Reports. 8: 12125. PMID 30108230 DOI: 10.1038/S41598-018-29709-8  0.416
2018 Kudo T, Wangemann P, Marcus DC. Claudin expression during early postnatal development of the murine cochlea Bmc Physiology. 18: 1-1. PMID 29368643 DOI: 10.1186/S12899-018-0035-1  0.393
2017 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ. Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 6. PMID 28994389 DOI: 10.7554/Elife.26851  0.564
2017 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ. Author response: Molecular architecture underlying fluid absorption by the developing inner ear Elife. DOI: 10.7554/Elife.26851.034  0.446
2016 Miyazaki H, Wangemann P, Marcus DC. The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion. Bmc Physiology. 17: 1. PMID 27515813 DOI: 10.1186/S12899-016-0024-1  0.369
2016 Nishio A, Ito T, Cheng H, Fitzgerald TS, Wangemann P, Griffith AJ. Slc26a4 Expression Prevents Fluctuation of Hearing in a Mouse Model of Large Vestibular Aqueduct Syndrome. Neuroscience. PMID 27155149 DOI: 10.1016/J.Neuroscience.2016.04.042  0.405
2015 Ito T, Nishio A, Wangemann P, Griffith AJ. Progressive irreversible hearing loss is caused by stria vascularis degeneration in an Slc26a4-insufficient mouse model of large vestibular aqueduct syndrome. Neuroscience. 310: 188-97. PMID 26363152 DOI: 10.1016/J.Neuroscience.2015.09.016  0.391
2015 Lu J, Aguilar A, Zou B, Bao W, Koldas S, Shi A, Desper J, Wangemann P, Xie XS, Hua DH. Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels. Bioorganic & Medicinal Chemistry. 23: 5985-98. PMID 26190460 DOI: 10.1016/J.Bmc.2015.06.055  0.307
2015 Morozko EL, Nishio A, Ingham NJ, Chandra R, Fitzgerald T, Martelletti E, Borck G, Wilson E, Riordan GP, Wangemann P, Forge A, Steel KP, Liddle RA, Friedman TB, Belyantseva IA. ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells. Human Molecular Genetics. 24: 609-24. PMID 25217574 DOI: 10.1093/Hmg/Ddu474  0.406
2014 Kim KX, Sanneman JD, Kim HM, Harbidge DG, Xu J, Soleimani M, Wangemann P, Marcus DC. Slc26a7 chloride channel activity and localization in mouse Reissner's membrane epithelium. Plos One. 9: e97191. PMID 24810589 DOI: 10.1371/Journal.Pone.0097191  0.43
2014 Ito T, Li X, Kurima K, Choi BY, Wangemann P, Griffith AJ. Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction. Neurobiology of Disease. 66: 53-65. PMID 24561068 DOI: 10.1016/J.Nbd.2014.02.002  0.554
2013 Ito T, Muskett J, Chattaraj P, Choi BY, Lee KY, Zalewski CK, King KA, Li X, Wangemann P, Shawker T, Brewer CC, Alper SL, Griffith AJ. SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct. World Journal of Otorhinolaryngology. 3: 26-34. PMID 25960948 DOI: 10.5319/wjo.v3.i2.26  0.449
2013 Wangemann P. Mouse models for pendrin-associated loss of cochlear and vestibular function. Cellular Physiology and Biochemistry. 32: 157-165. PMID 24429822 DOI: 10.1159/000356635  0.394
2013 Li X, Sanneman JD, Harbidge DG, Zhou F, Ito T, Nelson R, Picard N, Chambrey R, Eladari D, Miesner T, Griffith AJ, Marcus DC, Wangemann P. SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice. Plos Genetics. 9: e1003641. PMID 23874234 DOI: 10.1371/Journal.Pgen.1003641  0.57
2013 Li X, Zhou F, Marcus DC, Wangemann P. Endolymphatic Na⁺ and K⁺ concentrations during cochlear growth and enlargement in mice lacking Slc26a4/pendrin. Plos One. 8: e65977. PMID 23741519 DOI: 10.1371/Journal.Pone.0065977  0.563
2013 Reimann K, Krishnamoorthy G, Wangemann P. NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery. Plos One. 8: e53655. PMID 23301097 DOI: 10.1371/Journal.Pone.0053655  0.307
2011 Bronckers AL, Guo J, Zandieh-Doulabi B, Bervoets TJ, Lyaruu DM, Li X, Wangemann P, DenBesten P. Developmental expression of solute carrier family 26A member 4 (SLC26A4/pendrin) during amelogenesis in developing rodent teeth. European Journal of Oral Sciences. 119: 185-92. PMID 22243245 DOI: 10.1111/J.1600-0722.2011.00901.X  0.515
2011 Ito T, Choi BY, King KA, Zalewski CK, Muskett J, Chattaraj P, Shawker T, Reynolds JC, Butman JA, Brewer CC, Wangemann P, Alper SL, Griffith AJ. SLC26A4 genotypes and phenotypes associated with enlargement of the vestibular aqueduct. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 545-52. PMID 22116369 DOI: 10.1159/000335119  0.336
2011 Wangemann P. The role of pendrin in the development of the murine inner ear. Cellular Physiology and Biochemistry. 28: 527-534. PMID 22116367 DOI: 10.1159/000335113  0.385
2011 Choi BY, Kim HM, Ito T, Lee KY, Li X, Monahan K, Wen Y, Wilson E, Kurima K, Saunders TL, Petralia RS, Wangemann P, Friedman TB, Griffith AJ. Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition. The Journal of Clinical Investigation. 121: 4516-25. PMID 21965328 DOI: 10.1172/Jci59353  0.565
2011 Griffith AJ, Wangemann P. Hearing loss associated with enlargement of the vestibular aqueduct: mechanistic insights from clinical phenotypes, genotypes, and mouse models. Hearing Research. 281: 11-7. PMID 21669267 DOI: 10.1016/J.Heares.2011.05.009  0.377
2011 Kim H, Wangemann P. Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin Plos One. 6. PMID 21423764 DOI: 10.1371/Journal.Pone.0017949  0.394
2010 Kim H, Wangemann P. Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression. Plos One. 5. PMID 21103348 DOI: 10.1371/Journal.Pone.0014041  0.375
2010 Yamauchi D, Nakaya K, Raveendran NN, Harbidge DG, Singh R, Wangemann P, Marcus DC. Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth. Bmc Physiology. 10: 1. PMID 20113508 DOI: 10.1186/1472-6793-10-1  0.55
2009 Zdebik AA, Wangemann P, Jentsch TJ. Potassium ion movement in the inner ear: insights from genetic disease and mouse models. Physiology (Bethesda, Md.). 24: 307-16. PMID 19815857 DOI: 10.1152/Physiol.00018.2009  0.391
2009 Nakano Y, Kim SH, Kim HM, Sanneman JD, Zhang Y, Smith RJ, Marcus DC, Wangemann P, Nessler RA, Bánfi B. A claudin-9-based ion permeability barrier is essential for hearing. Plos Genetics. 5: e1000610. PMID 19696885 DOI: 10.1371/Journal.Pgen.1000610  0.448
2009 Wangemann P, Kim HM, Billings S, Nakaya K, Li X, Singh R, Sharlin DS, Forrest D, Marcus DC, Fong P. Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression. American Journal of Physiology. Renal Physiology. 297: F1435-47. PMID 19692489 DOI: 10.1152/Ajprenal.00011.2009  0.634
2009 Yang T, Gurrola JG, Wu H, Chiu SM, Wangemann P, Snyder PM, Smith RJ. Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome. American Journal of Human Genetics. 84: 651-7. PMID 19426954 DOI: 10.1016/J.Ajhg.2009.04.014  0.337
2008 Singh R, Wangemann P. Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model. American Journal of Physiology. Renal Physiology. 294: F139-48. PMID 17959752 DOI: 10.1152/Ajprenal.00433.2007  0.576
2007 Lang F, Vallon V, Knipper M, Wangemann P. Functional significance of channels and transporters expressed in the inner ear and kidney American Journal of Physiology-Cell Physiology. 293. PMID 17670895 DOI: 10.1152/Ajpcell.00024.2007  0.399
2007 Wangemann P, Nakaya K, Wu T, Maganti RJ, Itza EM, Sanneman JD, Harbidge DG, Billings S, Marcus DC. Loss of cochlear HCO3- secretion causes deafness via endolymphatic acidification and inhibition of Ca2+ reabsorption in a Pendred syndrome mouse model. American Journal of Physiology. Renal Physiology. 292: F1345-53. PMID 17299139 DOI: 10.1152/Ajprenal.00487.2006  0.459
2007 Nakaya K, Harbidge DG, Wangemann P, Schultz BD, Green ED, Wall SM, Marcus DC. Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels. American Journal of Physiology. Renal Physiology. 292: F1314-21. PMID 17200157 DOI: 10.1152/Ajprenal.00432.2006  0.353
2006 Jabba SV, Oelke A, Singh R, Maganti RJ, Fleming S, Wall SM, Everett LA, Green ED, Wangemann P. Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model. Bmc Medicine. 4: 37. PMID 17187680 DOI: 10.1186/1741-7015-4-37  0.564
2006 Wangemann P. Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential The Journal of Physiology. 576: 11-21. PMID 16857713 DOI: 10.1113/Jphysiol.2006.112888  0.383
2005 Scherer EQ, Arnold W, Wangemann P. Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery: a potential new treatment for sudden sensorineural hearing loss Bmc Ear, Nose and Throat Disorders. 5: 10-10. PMID 16316469 DOI: 10.1186/1472-6815-5-10  0.3
2005 Marcus DC, Liu J, Lee JH, Scherer EQ, Scofield MA, Wangemann P. Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium. Cell Communication and Signaling : Ccs. 3: 13. PMID 16266433 DOI: 10.1186/1478-811X-3-13  0.325
2005 Singh R, Maganti RJ, Jabba SV, Wang M, Deng G, Heath JD, Kurn N, Wangemann P. Microarray-based comparison of three amplification methods for nanogram amounts of total RNA. American Journal of Physiology. Cell Physiology. 288: C1179-89. PMID 15613496 DOI: 10.1152/Ajpcell.00258.2004  0.477
2004 Wangemann P, Itza EM, Albrecht B, Wu T, Jabba SV, Maganti RJ, Lee JH, Everett LA, Wall SM, Royaux IE, Green ED, Marcus DC. Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model. Bmc Medicine. 2: 30. PMID 15320950 DOI: 10.1186/1741-7015-2-30  0.356
2004 Pondugula SR, Sanneman JD, Wangemann P, Milhaud PG, Marcus DC. Glucocorticoids stimulate cation absorption by semicircular canal duct epithelium via epithelial sodium channel. American Journal of Physiology. Renal Physiology. 286: F1127-35. PMID 14996671 DOI: 10.1152/Ajprenal.00387.2003  0.351
2002 Scherer EQ, Herzog M, Wangemann P. Endothelin-1–Induced Vasospasms of Spiral Modiolar Artery Are Mediated by Rho-Kinase–Induced Ca2+ Sensitization of Contractile Apparatus and Reversed by Calcitonin Gene–Related Peptide Stroke. 33: 2965-2971. PMID 12468798 DOI: 10.1161/01.Str.0000043673.22993.Fd  0.302
2002 Herzog M, Scherer EQ, Albrecht B, Rorabaugh B, Scofield MA, Wangemann P. CGRP Receptors in the Gerbil Spiral Modiolar Artery Mediate a Sustained Vasodilation via a Transient cAMP-mediated Ca2+-decrease The Journal of Membrane Biology. 189: 225-236. PMID 12395287 DOI: 10.1007/S00232-002-1017-5  0.376
2002 Milhaud PG, Pondugula SR, Lee JH, Herzog M, Lehouelleur J, Wangemann P, Sans A, Marcus DC. Chloride secretion by semicircular canal duct epithelium is stimulated via beta 2-adrenergic receptors. American Journal of Physiology. Cell Physiology. 283: C1752-60. PMID 12388054 DOI: 10.1152/Ajpcell.00283.2002  0.338
2002 Cohen-Salmon M, Ott T, Michel V, Hardelin JP, Perfettini I, Eybalin M, Wu T, Marcus DC, Wangemann P, Willecke K, Petit C. Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death. Current Biology : Cb. 12: 1106-11. PMID 12121617 DOI: 10.1016/S0960-9822(02)00904-1  0.381
2002 Wangemann P. K(+) cycling and its regulation in the cochlea and the vestibular labyrinth. Audiology and Neuro-Otology. 7: 199-205. PMID 12097719 DOI: 10.1159/000063736  0.369
2002 Wangemann P. K+ cycling and the endocochlear potential. Hearing Research. 165: 1-9. PMID 12031509 DOI: 10.1016/S0378-5955(02)00279-4  0.373
2002 Wangemann P. Adrenergic and muscarinic control of cochlear endolymph production. Advances in Oto-Rhino-Laryngology. 59: 42-50. PMID 11885660 DOI: 10.1159/000059255  0.365
2002 Marcus DC, Wu T, Wangemann P, Kofuji P. KCNJ10 (Kir4.1) potassium channel knockout abolishes endocochlear potential. American Journal of Physiology. Cell Physiology. 282: C403-7. PMID 11788352 DOI: 10.1152/Ajpcell.00312.2001  0.367
2001 Wangemann P, Liu J, Scherer EQ, Herzog M, Shimozono M, Scofield MA. Muscarinic receptors control K+ secretion in inner ear strial marginal cells. The Journal of Membrane Biology. 182: 171-181. PMID 11547340 DOI: 10.1007/S00232-001-0042-0  0.328
2000 Wonneberger K, Scofield MA, Wangemann P. Evidence for a calcium-sensing receptor in the vascular smooth muscle cells of the spiral modiolar artery. The Journal of Membrane Biology. 175: 203-212. PMID 10833530 DOI: 10.1007/S00232001068  0.313
1998 Wangemann P, Cohn ES, Gruber DD, Gratton MA. Ca2+-dependence and nifedipine-sensitivity of vascular tone and contractility in the isolated superfused spiral modiolar artery in vitro. Hearing Research. 118: 90-100. PMID 9606064 DOI: 10.1016/S0378-5955(98)00017-3  0.318
1998 Shimozono M, Liu J, Scofield MA, Wangemann P. Vestibular dark cells contain an H^+/monocarboxylate-cotransporter in their apical and basolateral membrane The Journal of Membrane Biology. 163: 37-46. PMID 9569248 DOI: 10.1007/S002329900368  0.348
1997 Shimozono M, Scofield MA, Wangemann P. Functional evidence for a monocarboxylate transporter (MCT) in strial marginal cells and molecular evidence for MCT1 and MCT2 in stria vascularis. Hearing Research. 114: 213-222. PMID 9447934 DOI: 10.1016/S0378-5955(97)00165-2  0.336
1996 Vetter DE, Mann JR, Wangemann P, Liu J, McLaughlin KJ, Lesage F, Marcus DC, Lazdunski M, Heinemann SF, Barhanin J. Inner ear defects induced by null mutation of the isk gene. Neuron. 17: 1251-64. PMID 8982171 DOI: 10.1016/S0896-6273(00)80255-X  0.402
1996 Wangemann P, Shen Z, Liu J. K(+)-induced stimulation of K+ secretion involves activation of the IsK channel in vestibular dark cells. Hearing Research. 100: 201-210. PMID 8922995 DOI: 10.1016/0378-5955(96)00127-X  0.354
1996 Wangemann P, Liu J, Shiga N. Vestibular dark cells contain the Na+H+ exchanger NHE-1 in the basolateral membrane Hearing Research. 94: 94-106. PMID 8789815 DOI: 10.1016/0378-5955(96)00008-1  0.389
1995 Wangemann P. Comparison of ion transport mechanisms between vestibular dark cells and strial marginal cells. Hearing Research. 90: 149-157. PMID 8974992 DOI: 10.1016/0378-5955(95)00157-2  0.347
1995 Shen Z, Liu J, Marcus DC, Shiga N, Wangemann P. DIDS increases K+ secretion through an IsK channel in apical membrane of vestibular dark cell epithelium of gerbil. The Journal of Membrane Biology. 146: 283-291. PMID 8568843 DOI: 10.1007/Bf00233948  0.35
1995 Wangemann P, Liu J, Shiga N. The pH-sensitivity of Transepithelial K + Transport in Vestibular Dark Cells The Journal of Membrane Biology. 147: 255-262. PMID 8558591 DOI: 10.1007/Bf00234523  0.302
1995 Wangemann P, Liu J, Marcus DC. Ion transport mechanisms responsible for K+ secretion and the transepithelial voltage across marginal cells of stria vascularis in vitro. Hearing Research. 84: 19-29. PMID 7642451 DOI: 10.1016/0378-5955(95)00009-S  0.384
1995 Shiga N, Wangemann P. Ion selectivity of volume regulatory mechanisms present during a hypoosmotic challenge in vestibular dark cells. Biochimica Et Biophysica Acta. 1240: 48-54. PMID 7495847 DOI: 10.1016/0005-2736(95)00175-1  0.368
1993 Takeuchi S, Wangemann P. Aminoglycoside antibiotics inhibit maxi-K+ channel in single isolated cochlear efferent nerve terminals Hearing Research. 67: 13-19. PMID 8340264 DOI: 10.1016/0378-5955(93)90227-R  0.319
1993 Marcus DC, Takeuchi S, Wangemann P. Two types of chloride channel in the basolateral membrane of vestibular dark cells. Hearing Research. 69: 124-132. PMID 8226332 DOI: 10.1016/0378-5955(93)90100-F  0.304
1993 Wangemann P, Shiga N, Marcus DC. The Na+/H+ exchanger in transitional cells of the inner ear Hearing Research. 69: 107-114. PMID 8226330 DOI: 10.1016/0378-5955(93)90098-L  0.31
1993 Wangemann P, Takeuchi S. Maxi-K+ channel in single isolated cochlear efferent nerve terminals. Hearing Research. 66: 123-129. PMID 7685332 DOI: 10.1016/0378-5955(93)90133-L  0.337
1992 Takeuchi S, Marcus DC, Wangemann P. Maxi K+ channel in apical membrane of vestibular dark cells. American Journal of Physiology-Cell Physiology. 262. PMID 1616010 DOI: 10.1152/Ajpcell.1992.262.6.C1430  0.35
1992 Wangemann P, Shiga N, Welch C, Marcus DC. Evidence for the involvement of a K+ channel in isosmotic cell shrinking in vestibular dark cells American Journal of Physiology-Cell Physiology. 263. PMID 1415511 DOI: 10.1152/Ajpcell.1992.263.3.C616  0.358
1992 Takeuchi S, Marcus DC, Wangemann P. Ca2+-activated nonselective cation, maxi K+ and Cl− channels in apical membrane of marginal cells of stria vascularis Hearing Research. 61: 86-96. PMID 1382049 DOI: 10.1016/0378-5955(92)90039-P  0.362
1992 Marcus DC, Takeuchi S, Wangemann P. Ca(2+)-activated nonselective cation channel in apical membrane of vestibular dark cells. American Journal of Physiology-Cell Physiology. 262. PMID 1377443 DOI: 10.1152/Ajpcell.1992.262.6.C1423  0.385
1992 Wangemann P, Marcus DC. The membrane potential of vestibular dark cells is controlled by a large Cl- conductance. Hearing Research. 62: 149-156. PMID 1331015 DOI: 10.1016/0378-5955(92)90180-U  0.306
1991 Wittner M, Stefano AD, Wangemann P, Greger R. How do loop diuretics act Drugs. 41: 1-13. PMID 1712711 DOI: 10.2165/00003495-199100413-00003  0.34
1990 Wangemann P, Marcus DC. K(+)-induced swelling of vestibular dark cells is dependent on Na+ and Cl- and inhibited by piretanide. PflüGers Archiv: European Journal of Physiology. 416: 262-269. PMID 1696372 DOI: 10.1007/Bf00392062  0.325
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