Kuo-Kuang Wen, Ph.D. - Publications

Affiliations: 
2000 University of Iowa, Iowa City, IA 
Area:
Cell Biology, Molecular Biology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, et al. Actin nucleators safeguard replication forks by limiting nascent strand degradation. Nucleic Acids Research. PMID 37224534 DOI: 10.1093/nar/gkad369  0.385
2023 Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, et al. Actin nucleators safeguard replication forks by limiting nascent strand degradation. Biorxiv : the Preprint Server For Biology. PMID 36711944 DOI: 10.1101/2023.01.12.523639  0.385
2018 Rubenstein PA, Wen KK. NATure of actin amino-terminal acetylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632202 DOI: 10.1073/Pnas.1803804115  0.699
2016 Lee CY, Lou J, Wen KK, McKane M, Eskin SG, Rubenstein PA, Chien S, Ono S, Zhu C, McIntire LV. Regulation of actin catch-slip bonds with a RhoA-formin module. Scientific Reports. 6: 35058. PMID 27731359 DOI: 10.1038/Srep35058  0.682
2015 Rubenstein PA, Wen KK. Mutant vascular actin is a TAAD misbehaving. Proceedings of the National Academy of Sciences of the United States of America. 112: 9500-1. PMID 26204915 DOI: 10.1073/Pnas.1512086112  0.726
2015 Rubenstein PA, Wen KK. Mutant vascular actin is a TAAD misbehaving Proceedings of the National Academy of Sciences of the United States of America. 112: 9500-9501. DOI: 10.1073/pnas.1512086112  0.691
2014 Pierick AR, McKane M, Wen KK, Bartlett HL. Aip1p dynamics are altered by the R256H mutation in actin. Journal of Visualized Experiments : Jove. e51551. PMID 25146730 DOI: 10.3791/51551  0.565
2014 Rubenstein PA, Wen KK. Insights into the effects of disease-causing mutations in human actins. Cytoskeleton (Hoboken, N.J.). 71: 211-29. PMID 24574087 DOI: 10.1002/Cm.21169  0.724
2013 Wen KK, McKane M, Rubenstein PA. Importance of a Lys113-Glu195 intermonomer ionic bond in F-actin stabilization and regulation by yeast formins Bni1p and Bnr1p. The Journal of Biological Chemistry. 288: 19140-53. PMID 23653364 DOI: 10.1074/Jbc.M113.474122  0.793
2013 Johnston JJ, Wen KK, Keppler-Noreuil K, McKane M, Maiers JL, Greiner A, Sapp JC, Demali KA, Rubenstein PA, Biesecker LG. Functional analysis of a de novo ACTB mutation in a patient with atypical Baraitser-Winter syndrome. Human Mutation. 34: 1242-9. PMID 23649928 DOI: 10.1002/Humu.22350  0.594
2013 Lee CY, Lou J, Wen KK, McKane M, Eskin SG, Ono S, Chien S, Rubenstein PA, Zhu C, McIntire LV. Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds. Proceedings of the National Academy of Sciences of the United States of America. 110: 5022-7. PMID 23460697 DOI: 10.1073/Pnas.1218407110  0.695
2012 Malloy LE, Wen KK, Pierick AR, Wedemeyer EW, Bergeron SE, Vanderpool ND, McKane M, Rubenstein PA, Bartlett HL. Thoracic aortic aneurysm (TAAD)-causing mutation in actin affects formin regulation of polymerization. The Journal of Biological Chemistry. 287: 28398-408. PMID 22753406 DOI: 10.1074/Jbc.M112.371914  0.808
2012 Glenn NO, McKane M, Kohli V, Wen KK, Rubenstein PA, Bartman T, Sumanas S. The W-loop of alpha-cardiac actin is critical for heart function and endocardial cushion morphogenesis in zebrafish. Molecular and Cellular Biology. 32: 3527-40. PMID 22751927 DOI: 10.1128/Mcb.00486-12  0.732
2011 Wen KK, McKane M, Stokasimov E, Rubenstein PA. Mutant profilin suppresses mutant actin-dependent mitochondrial phenotype in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 286: 41745-57. PMID 21956104 DOI: 10.1074/Jbc.M110.217661  0.815
2011 Stark BC, Wen KK, Allingham JS, Rubenstein PA, Lord M. Functional adaptation between yeast actin and its cognate myosin motors. The Journal of Biological Chemistry. 286: 30384-92. PMID 21757693 DOI: 10.1074/Jbc.M111.262899  0.742
2011 Bergeron SE, Wedemeyer EW, Lee R, Wen KK, McKane M, Pierick AR, Berger AP, Rubenstein PA, Bartlett HL. Allele-specific effects of thoracic aortic aneurysm and dissection alpha-smooth muscle actin mutations on actin function. The Journal of Biological Chemistry. 286: 11356-69. PMID 21288906 DOI: 10.1074/Jbc.M110.203174  0.807
2010 Wen KK, McKane M, Stokasimov E, Fields J, Rubenstein PA. A potential yeast actin allosteric conduit dependent on hydrophobic core residues val-76 and trp-79. The Journal of Biological Chemistry. 285: 21185-94. PMID 20442407 DOI: 10.1074/Jbc.M110.121426  0.774
2009 Wen KK, Rubenstein PA, DeMali KA. Vinculin nucleates actin polymerization and modifies actin filament structure. The Journal of Biological Chemistry. 284: 30463-73. PMID 19736312 DOI: 10.1074/Jbc.M109.021295  0.782
2009 Wen KK, Rubenstein PA. Differential regulation of actin polymerization and structure by yeast formin isoforms. The Journal of Biological Chemistry. 284: 16776-83. PMID 19386598 DOI: 10.1074/Jbc.M109.006981  0.776
2008 Wen KK, McKane M, Houtman JC, Rubenstein PA. Control of the ability of profilin to bind and facilitate nucleotide exchange from G-actin. The Journal of Biological Chemistry. 283: 9444-53. PMID 18223293 DOI: 10.1074/Jbc.M709806200  0.724
2006 McKane M, Wen KK, Meyer A, Rubenstein PA. Effect of the substitution of muscle actin-specific subdomain 1 and 2 residues in yeast actin on actin function. The Journal of Biological Chemistry. 281: 29916-28. PMID 16882670 DOI: 10.1074/Jbc.M602251200  0.759
2006 Bryan KE, Wen KK, Zhu M, Rendtorff ND, Feldkamp M, Tranebjaerg L, Friderici KH, Rubenstein PA. Effects of human deafness gamma-actin mutations (DFNA20/26) on actin function. The Journal of Biological Chemistry. 281: 20129-39. PMID 16690605 DOI: 10.1074/Jbc.M601514200  0.838
2006 Chen W, Wen KK, Sens AE, Rubenstein PA. Differential interaction of cardiac, skeletal muscle, and yeast tropomyosins with fluorescent (pyrene235) yeast actin. Biophysical Journal. 90: 1308-18. PMID 16326906 DOI: 10.1529/Biophysj.105.064634  0.712
2005 Rubenstein PA, Wen KK. Lights, camera, actin. Iubmb Life. 57: 683-7. PMID 16223708 DOI: 10.1080/15216540500306991  0.764
2005 McKane M, Wen KK, Boldogh IR, Ramcharan S, Pon LA, Rubenstein PA. A mammalian actin substitution in yeast actin (H372R) causes a suppressible mitochondria/vacuole phenotype. The Journal of Biological Chemistry. 280: 36494-501. PMID 16118223 DOI: 10.1074/Jbc.M506970200  0.803
2005 Wen KK, Rubenstein PA. Acceleration of yeast actin polymerization by yeast Arp2/3 complex does not require an Arp2/3-activating protein. The Journal of Biological Chemistry. 280: 24168-74. PMID 15857833 DOI: 10.1074/Jbc.M502024200  0.777
2004 Wen KK, Blake MS, Rubenstein PA. Neisseria gonorrhoeae porin, P.IB, causes release of ATP from yeast actin. Journal of Muscle Research and Cell Motility. 25: 343-50. PMID 15548863 DOI: 10.1007/S10974-004-6069-Y  0.733
2004 Bartman T, Walsh EC, Wen KK, McKane M, Ren J, Alexander J, Rubenstein PA, Stainier DY. Early myocardial function affects endocardial cushion development in zebrafish. Plos Biology. 2: E129. PMID 15138499 DOI: 10.1371/Journal.Pbio.0020129  0.614
2003 Wen KK, Rubenstein PA. Biochemical consequences of the cardiofunk (R177H) mutation in yeast actin. The Journal of Biological Chemistry. 278: 48386-94. PMID 13129918 DOI: 10.1074/Jbc.M308980200  0.799
2002 Kusner DJ, Barton JA, Wen KK, Wang X, Rubenstein PA, Iyer SS. Regulation of phospholipase D activity by actin. Actin exerts bidirectional modulation of Mammalian phospholipase D activity in a polymerization-dependent, isoform-specific manner. The Journal of Biological Chemistry. 277: 50683-92. PMID 12388543 DOI: 10.1074/Jbc.M209221200  0.749
2002 Wen KK, Yao X, Rubenstein PA. GTP-yeast actin. The Journal of Biological Chemistry. 277: 41101-9. PMID 12191996 DOI: 10.1074/Jbc.M204025200  0.82
2000 Wen KK, Kuang B, Rubenstein PA. Tropomyosin-dependent filament formation by a polymerization-defective mutant yeast actin (V266G,L267G). The Journal of Biological Chemistry. 275: 40594-600. PMID 10998421 DOI: 10.1074/Jbc.M007201200  0.786
2000 Wen KK, Giardina PC, Blake MS, Edwards J, Apicella MA, Rubenstein PA. Interaction of the gonococcal porin P.IB with G- and F-actin. Biochemistry. 39: 8638-47. PMID 10913272 DOI: 10.1021/Bi000241J  0.744
1998 Eads JC, Mahoney NM, Vorobiev S, Bresnick AR, Wen KK, Rubenstein PA, Haarer BK, Almo SC. Structure determination and characterization of Saccharomyces cerevisiae profilin. Biochemistry. 37: 11171-81. PMID 9698363 DOI: 10.1021/Bi9720033  0.705
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