Year |
Citation |
Score |
2024 |
Phillips S, Chatham JC, McMahon LL. Forskolin reverses the O-GlcNAcylation dependent decrease in GABAR current amplitude at hippocampal synapses possibly at a neurosteroid site on GABARs. Scientific Reports. 14: 17461. PMID 39075105 DOI: 10.1038/s41598-024-66025-w |
0.332 |
|
2024 |
Phillips S, Chatham JC, McMahon LL. Forskolin reverses the O-GlcNAcylation dependent decrease in GABAAR current amplitude at hippocampal synapses possibly at a neurosteroid site on GABAARs. Research Square. PMID 38659738 DOI: 10.21203/rs.3.rs-4140038/v1 |
0.328 |
|
2024 |
Phillips S, Chatham JC, McMahon L. Forskolin reverses the O-GlcNAcylation dependent decrease in GABAAR current amplitude at hippocampal synapses possibly through a neurosteroid site on GABAARs. Biorxiv : the Preprint Server For Biology. PMID 38496430 DOI: 10.1101/2024.03.06.583612 |
0.328 |
|
2023 |
Ha CM, Bakshi S, Brahma MK, Potter LA, Chang SF, Sun Z, Benavides GA, He L, Umbarkar P, Zou L, Curfman S, Sunny S, Paterson AJ, Rajasekaran NS, Barnes JW, ... ... Chatham JC, et al. Sustained Increases in Cardiomyocyte Protein -Linked β-N-Acetylglucosamine Levels Lead to Cardiac Hypertrophy and Reduced Mitochondrial Function Without Systolic Contractile Impairment. Journal of the American Heart Association. 12: e029898. PMID 37750556 DOI: 10.1161/JAHA.123.029898 |
0.305 |
|
2023 |
Zou L, Zhang D, Ha CM, Wende AR, Chatham JC. Best Practices in assessing Cardiac Protein O-GlcNAcylation by immunoblot. American Journal of Physiology. Heart and Circulatory Physiology. PMID 37539459 DOI: 10.1152/ajpheart.00104.2023 |
0.379 |
|
2021 |
Mueller T, Ouyang X, Johnson MS, Qian WJ, Chatham JC, Darley-Usmar V, Zhang J. New Insights Into the Biology of Protein O-GlcNAcylation: Approaches and Observations. Frontiers in Aging. 1: 620382. PMID 35822169 DOI: 10.3389/fragi.2020.620382 |
0.383 |
|
2021 |
Huynh VN, Wang S, Ouyang X, Wani WY, Johnson MS, Chacko BK, Jegga AG, Qian WJ, Chatham JC, Darley-Usmar VM, Zhang J. Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases. Frontiers in Aging. 2: 757801. PMID 35822049 DOI: 10.3389/fragi.2021.757801 |
0.343 |
|
2021 |
Zou L, Collins HE, Young ME, Zhang J, Wende AR, Darley-Usmar VM, Chatham JC. The Identification of a Novel Calcium-Dependent Link Between NAD and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress. Frontiers in Molecular Biosciences. 8: 780865. PMID 34950703 DOI: 10.3389/fmolb.2021.780865 |
0.438 |
|
2021 |
Prakoso D, Lim SY, Erickson JR, Wallace RS, Lees JG, Tate M, Kiriazis H, Donner DG, Henstridge DC, Davey JR, Qian H, Deo M, Parry LJ, Davidoff AJ, Gregorevic P, ... Chatham JC, et al. Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart. Cardiovascular Research. PMID 33576380 DOI: 10.1093/cvr/cvab043 |
0.353 |
|
2020 |
Chatham JC, Young ME, Zhang J. Reprint of: Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications. Current Opinion in Pharmacology. 54: 209-220. PMID 33278716 DOI: 10.1016/j.coph.2020.11.005 |
0.414 |
|
2020 |
Chatham JC, Young ME, Zhang J. Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications. Current Opinion in Pharmacology. 57: 1-12. PMID 32937226 DOI: 10.1016/J.Coph.2020.08.005 |
0.508 |
|
2020 |
Brahma MK, Ha CM, Pepin ME, Mia S, Sun Z, Chatham JC, Habegger KM, Abel ED, Paterson AJ, Young ME, Wende AR. Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization. Journal of the American Heart Association. 9: e013039. PMID 32750298 DOI: 10.1161/Jaha.119.013039 |
0.39 |
|
2020 |
Chatham JC, Zhang J, Wende AR. Role of O-Linked N-acetylglucosamine (O-GlcNAc) Protein Modification in Cellular (Patho)Physiology. Physiological Reviews. PMID 32730113 DOI: 10.1152/Physrev.00043.2019 |
0.496 |
|
2020 |
Stewart LT, Abiraman K, Chatham JC, McMahon LL. Increased O-GlcNAcylation rapidly decreases GABAR currents in hippocampus but depresses neuronal output. Scientific Reports. 10: 7494. PMID 32366857 DOI: 10.1038/S41598-020-63188-0 |
0.452 |
|
2020 |
De Blasio MJ, Huynh N, Deo M, Dubrana LE, Walsh J, Willis A, Prakoso D, Kiriazis H, Donner DG, Chatham JC, Ritchie RH. Defining the Progression of Diabetic Cardiomyopathy in a Mouse Model of Type 1 Diabetes. Frontiers in Physiology. 11: 124. PMID 32153425 DOI: 10.3389/Fphys.2020.00124 |
0.307 |
|
2020 |
Collins HE, Chatham JC. Regulation of cardiac O-GlcNAcylation: More than just nutrient availability. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165712. PMID 32014551 DOI: 10.1016/J.Bbadis.2020.165712 |
0.53 |
|
2020 |
Olson AK, Bouchard B, Zhu WZ, Chatham JC, Des Rosiers C. First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart. The Journal of Biological Chemistry. PMID 31915250 DOI: 10.1074/Jbc.Ra119.010565 |
0.473 |
|
2019 |
Ferron M, Cadiet J, Persello A, Prat V, Denis M, Erraud A, Aillerie V, Mevel M, Bigot E, Chatham JC, Gauthier C, Rozec B, Lauzier B. O-GlcNAc stimulation: A new metabolic approach to treat septic shock. Scientific Reports. 9: 18751. PMID 31822776 DOI: 10.1038/S41598-019-55381-7 |
0.435 |
|
2019 |
Zhang J, Chatham J, Young ME. Circadian Regulation of Cardiac Physiology: Rhythms That Keep the Heart Beating. Annual Review of Physiology. PMID 31589825 DOI: 10.1146/Annurev-Physiol-020518-114349 |
0.332 |
|
2019 |
Wright JN, Benavides GA, Johnson MS, Wani W, Ouyang X, Zou L, Collins HE, Zhang J, Darley-Usmar V, Chatham JC. Acute increases in O-GlcNAc indirectly impairs mitochondrial bioenergetics through dysregulation of LonP1-mediated mitochondrial protein complex turnover. American Journal of Physiology. Cell Physiology. PMID 30865517 DOI: 10.1152/Ajpcell.00491.2018 |
0.436 |
|
2018 |
Collins HE, Pat BM, Zou L, Litovsky SH, Wende AR, Young ME, Chatham JC. Novel role of the ER/SR Ca sensor, STIM1, in regulation of cardiac metabolism. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30575437 DOI: 10.1152/Ajpheart.00544.2018 |
0.43 |
|
2018 |
Das S, Bailey SK, Metge BJ, Hanna A, Hinshaw DC, Mota M, Forero-Torres A, Chatham JC, Samant RS, Shevde LA. O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30420690 DOI: 10.1038/S41374-018-0122-8 |
0.453 |
|
2018 |
Brewer RA, Collins HE, Berry RD, Brahma MK, Tirado BA, Peliciari-Garcia RA, Stanley HL, Wende AR, Taegtmeyer H, Rajasekaran NS, Darley-Usmar V, Zhang J, Frank SJ, Chatham JC, Young ME. Temporal partitioning of adaptive responses of the murine heart to fasting. Life Sciences. PMID 29410090 DOI: 10.1016/J.Lfs.2018.01.031 |
0.333 |
|
2018 |
Prakoso D, Kiriazis H, Tate M, Qian H, Deo M, Parry L, Gregorevic P, Du X, Chatham J, Blasio MD, Ritchie R. 5213Manipulation of cardiac O-GlcNAc modification alters cardiac function and remodelling in the setting of diabetic cardiomyopathy European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy566.5213 |
0.428 |
|
2018 |
Prakoso D, Deo M, Kiriazis H, Tate M, Qian H, Parry L, Gregorevic P, Du X, Chatham J, Blasio MD, Ritchie R. The Role of Sustained Glucose-Driven Post–Translational Protein Modification on the Myocardium: Implications for Diabetes Induced-Heart Failure Heart Lung and Circulation. 27. DOI: 10.1016/J.Hlc.2018.06.217 |
0.366 |
|
2017 |
Stewart LT, Khan AU, Wang K, Pizarro D, Pati S, Buckingham SC, Olsen ML, Chatham JC, McMahon LL. Acute Increases in Protein O-GlcNAcylation Dampen Epileptiform Activity in Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28760863 DOI: 10.1523/Jneurosci.0173-16.2017 |
0.474 |
|
2017 |
McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Dale Abel E, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, ... Chatham JC, et al. Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart. Journal of Molecular and Cellular Cardiology. PMID 28736261 DOI: 10.1016/J.Yjmcc.2017.07.005 |
0.37 |
|
2017 |
Wani WY, Ouyang X, Benavides GA, Redmann M, Cofield SS, Shacka JJ, Chatham JC, Darley-Usmar V, Zhang J. O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson's disease. Molecular Brain. 10: 32. PMID 28724388 DOI: 10.1016/J.Freeradbiomed.2017.10.282 |
0.472 |
|
2017 |
Wright JN, Collins HE, Wende AR, Chatham JC. O-GlcNAcylation and cardiovascular disease. Biochemical Society Transactions. 45: 545-553. PMID 28408494 DOI: 10.1042/Bst20160164 |
0.507 |
|
2017 |
Prakoso D, Kiriazis H, Tate M, Qian H, Deo M, Parry L, Gregorevic P, Du X, Chatham J, Blasio MD, Ritchie R. Using Gene Delivery to Target Cardiac O-GlcNAc Protein Modifications in the Diabetic Heart: Impact on Left Ventricular (LV) Function Heart Lung and Circulation. 26. DOI: 10.1016/J.Hlc.2017.06.157 |
0.415 |
|
2016 |
Qin CX, Sleaby R, Davidoff AJ, Bell JR, De Blasio MJ, Delbridge LM, Chatham JC, Ritchie RH. INSIGHTS INTO THE ROLE OF MALADAPTIVE HEXOSAMINE BIOSYNTHESIS AND O-GLCNACYLATION IN DEVELOPMENT OF DIABETIC CARDIAC COMPLICATIONS. Pharmacological Research. PMID 27988387 DOI: 10.1016/J.Phrs.2016.12.016 |
0.474 |
|
2016 |
Wani WY, Chatham JC, Darley-Usmar V, McMahon LL, Zhang J. O-GlcNAcylation and neurodegeneration. Brain Research Bulletin. PMID 27497832 DOI: 10.1016/J.Brainresbull.2016.08.002 |
0.473 |
|
2016 |
Wende AR, Young ME, Chatham J, Zhang J, Rajasekaran NS, Darley-Usmar VM. Redox Biology and the Interface Between Bioenergetics, Autophagy and Circadian Control of Metabolism. Free Radical Biology & Medicine. PMID 27242268 DOI: 10.1016/J.Freeradbiomed.2016.05.022 |
0.414 |
|
2016 |
Chen J, Young ME, Chatham JC, Crossman DK, Dell'Italia LJ, Shalev A. TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00151.2016. PMID 27199118 DOI: 10.1152/Ajpheart.00151.2016 |
0.302 |
|
2016 |
Ferron M, Cadiet J, Prat V, Erraud A, Aillerie V, Mevel M, Chatham J, Rozec B, Lauzier B, Gauthier C. 0011 : In early phase of septic shock, O-GlcNAc improves cardiovascular function without modification of autophagic or inflammatory pathways Archives of Cardiovascular Diseases Supplements. 8: 235. DOI: 10.1016/S1878-6480(16)30446-3 |
0.405 |
|
2016 |
Ferron M, Cadiet J, Prat V, Erraud A, Grabherr A, Aillerie V, Mevel M, Chatham J, Rozec B, Gauthier C, Lauzier B. 0347: Beneficial cardiovascular effects of O-GlcNAc stimulation in early phase of septic shock Archives of Cardiovascular Diseases Supplements. 8: 89. DOI: 10.1016/S1878-6480(16)30255-5 |
0.411 |
|
2016 |
Blasio MD, Prakoso D, Qin C, Rosli S, Kiriazis H, Du X, Chatham J, McMullen J, Ritchie R. Cardiac-Specific Insulin-like Growth Factor-1 Receptor (IGF-1R) Expression Attenuates Upregulation of Left Ventricular Hexosamine Biosynthesis (HBP) Flux and Oxidative Stress in Diabetic Mouse Myocardium Heart Lung and Circulation. 25. DOI: 10.1016/J.Hlc.2016.06.172 |
0.301 |
|
2016 |
Wani W, Chatham J, Zhang JZ. Hyper-O-GlcNAcylation Attenuates Autophagic Flux in an MTOR Dependent Manner and Leads to Accumulation of α-Synuclein in Neurons Free Radical Biology and Medicine. 100. DOI: 10.1016/J.Freeradbiomed.2016.10.446 |
0.453 |
|
2015 |
Peliciari-Garcia RA, Goel M, Aristorenas JA, Shah K, He L, Yang Q, Shalev A, Bailey SM, Prabhu SD, Chatham JC, Gamble KL, Young ME. Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice. Biochimica Et Biophysica Acta. PMID 26721420 DOI: 10.1016/J.Bbalip.2015.12.012 |
0.374 |
|
2015 |
Wani WY, Boyer-Guittaut M, Dodson M, Chatham J, Darley-Usmar V, Zhang J. Regulation of autophagy by protein post-translational modification. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 14-25. PMID 25365205 DOI: 10.1038/Labinvest.2014.131 |
0.365 |
|
2015 |
Collins HE, Chatham JC. Non-voltage-gated Ca²⁺ entry pathways in the heart: the untold STOrai? Cardiovascular Research. 105: 233-4. PMID 25280892 DOI: 10.1093/Cvr/Cvu217 |
0.368 |
|
2015 |
Ferron M, Prat V, Roul D, Guivarc’H E, Hervault M, Erraud A, Aillerie V, Grabherr A, Mevel M, Chatham J, Lauzier B, Rozec B, Gauthier C. 0311 : Beneficial systemic effects of O-GlcNAc stimulation in early phase of sepsis Archives of Cardiovascular Diseases Supplements. 7: 174. DOI: 10.1016/S1878-6480(15)30119-1 |
0.366 |
|
2014 |
Marsh SA, Collins HE, Chatham JC. Protein O-GlcNAcylation and cardiovascular (patho)physiology. The Journal of Biological Chemistry. 289: 34449-56. PMID 25336635 DOI: 10.1074/Jbc.R114.585984 |
0.507 |
|
2014 |
Young ME, Brewer RA, Peliciari-Garcia RA, Collins HE, He L, Birky TL, Peden BW, Thompson EG, Ammons BJ, Bray MS, Chatham JC, Wende AR, Yang Q, Chow CW, Martino TA, et al. Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart. Journal of Biological Rhythms. 29: 257-76. PMID 25238855 DOI: 10.1177/0748730414543141 |
0.378 |
|
2014 |
Liu J, Wang P, Zou L, Qu J, Litovsky S, Umeda P, Zhou L, Chatham J, Marsh SA, Dell'Italia LJ, Lloyd SG. High-fat, low-carbohydrate diet promotes arrhythmic death and increases myocardial ischemia-reperfusion injury in rats. American Journal of Physiology. Heart and Circulatory Physiology. 307: H598-608. PMID 24929857 DOI: 10.1152/Ajpheart.00058.2014 |
0.369 |
|
2014 |
Collins HE, He L, Zou L, Qu J, Zhou L, Litovsky SH, Yang Q, Young ME, Marchase RB, Chatham JC. Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1231-9. PMID 24585777 DOI: 10.1152/Ajpheart.00075.2014 |
0.396 |
|
2014 |
Heath JM, Sun Y, Yuan K, Bradley WE, Litovsky S, Dell'Italia LJ, Chatham JC, Wu H, Chen Y. Activation of AKT by O-linked N-acetylglucosamine induces vascular calcification in diabetes mellitus. Circulation Research. 114: 1094-102. PMID 24526702 DOI: 10.1161/Circresaha.114.302968 |
0.452 |
|
2014 |
Taylor EW, Wang K, Nelson AR, Bredemann TM, Fraser KB, Clinton SM, Puckett R, Marchase RB, Chatham JC, McMahon LL. O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10-21. PMID 24381264 DOI: 10.1523/Jneurosci.4761-12.2014 |
0.449 |
|
2014 |
Zou L, Chatham J. Nicotinamide adenine dinucleotide hydrate (NAD+) regulates glucose deprivation-induced activation of protein O-GlcNAcylation, ER stress and autophagy (1154.2) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1154.2 |
0.477 |
|
2013 |
Collins HE, Zhu-Mauldin X, Marchase RB, Chatham JC. STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathology. American Journal of Physiology. Heart and Circulatory Physiology. 305: H446-58. PMID 23792674 DOI: 10.1152/Ajpheart.00104.2013 |
0.711 |
|
2013 |
Lauzier B, Vaillant F, Merlen C, Gélinas R, Bouchard B, Rivard ME, Labarthe F, Dolinsky VW, Dyck JR, Allen BG, Chatham JC, Des Rosiers C. Metabolic effects of glutamine on the heart: anaplerosis versus the hexosamine biosynthetic pathway. Journal of Molecular and Cellular Cardiology. 55: 92-100. PMID 23201305 DOI: 10.1016/J.Yjmcc.2012.11.008 |
0.376 |
|
2013 |
McLarty JL, Marsh SA, Chatham JC. Post-translational protein modification by O-linked N-acetyl-glucosamine: its role in mediating the adverse effects of diabetes on the heart. Life Sciences. 92: 621-7. PMID 22985933 DOI: 10.1016/J.Lfs.2012.08.006 |
0.549 |
|
2013 |
Chatham JC, Young ME. Regulation of myocardial metabolism by the cardiomyocyte circadian clock. Journal of Molecular and Cellular Cardiology. 55: 139-46. PMID 22766272 DOI: 10.1016/J.Yjmcc.2012.06.016 |
0.38 |
|
2013 |
Marsh SA, Powell PC, Dell'italia LJ, Chatham JC. Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart. Life Sciences. 92: 648-56. PMID 22728715 DOI: 10.1016/J.Lfs.2012.06.011 |
0.468 |
|
2012 |
Zhu-Mauldin X, Marsh SA, Zou L, Marchase RB, Chatham JC. Modification of STIM1 by O-linked N-acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes. The Journal of Biological Chemistry. 287: 39094-106. PMID 22992728 DOI: 10.1074/Jbc.M112.383778 |
0.749 |
|
2012 |
Chatham JC, Young ME. Metabolic remodeling in the hypertrophic heart: fuel for thought. Circulation Research. 111: 666-8. PMID 22935530 DOI: 10.1161/Circresaha.112.277392 |
0.368 |
|
2012 |
Zou L, Zhu-Mauldin X, Marchase RB, Paterson AJ, Liu J, Yang Q, Chatham JC. Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent. The Journal of Biological Chemistry. 287: 34419-31. PMID 22908225 DOI: 10.1074/Jbc.M112.393207 |
0.745 |
|
2012 |
Hilgers RH, Xing D, Gong K, Chen YF, Chatham JC, Oparil S. Acute O-GlcNAcylation prevents inflammation-induced vascular dysfunction. American Journal of Physiology. Heart and Circulatory Physiology. 303: H513-22. PMID 22777418 DOI: 10.1152/Ajpheart.01175.2011 |
0.486 |
|
2012 |
Cha-Molstad H, Xu G, Chen J, Jing G, Young ME, Chatham JC, Shalev A. Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes. Molecular Pharmacology. 82: 541-9. PMID 22734068 DOI: 10.1124/Mol.112.078253 |
0.339 |
|
2012 |
Medford HM, Chatham JC, Marsh SA. Chronic ingestion of a Western diet increases O-linked-β-N- acetylglucosamine (O-GlcNAc) protein modification in the rat heart Life Sciences. 90: 883-888. PMID 22575823 DOI: 10.1016/J.Lfs.2012.04.030 |
0.503 |
|
2012 |
Darley-Usmar VM, Ball LE, Chatham JC. Protein O-linked β-N-acetylglucosamine: a novel effector of cardiomyocyte metabolism and function. Journal of Molecular and Cellular Cardiology. 52: 538-49. PMID 21878340 DOI: 10.1016/J.Yjmcc.2011.08.009 |
0.534 |
|
2011 |
Durgan DJ, Pat BM, Laczy B, Bradley JA, Tsai JY, Grenett MH, Ratcliffe WF, Brewer RA, Nagendran J, Villegas-Montoya C, Zou C, Zou L, Johnson RL, Dyck JR, Bray MS, ... ... Chatham JC, et al. O-GlcNAcylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock. The Journal of Biological Chemistry. 286: 44606-19. PMID 22069332 DOI: 10.1074/Jbc.M111.278903 |
0.509 |
|
2011 |
Xing D, Gong K, Feng W, Nozell SE, Chen YF, Chatham JC, Oparil S. O-GlcNAc modification of NFκB p65 inhibits TNF-α-induced inflammatory mediator expression in rat aortic smooth muscle cells. Plos One. 6: e24021. PMID 21904602 DOI: 10.1371/Journal.Pone.0024021 |
0.379 |
|
2011 |
Laczy B, Fülöp N, Onay-Besikci A, Des Rosiers C, Chatham JC. Acute regulation of cardiac metabolism by the hexosamine biosynthesis pathway and protein O-GlcNAcylation. Plos One. 6: e18417. PMID 21494549 DOI: 10.1371/Journal.Pone.0018417 |
0.518 |
|
2011 |
Des Rosiers C, Labarthe F, Lloyd SG, Chatham JC. Cardiac anaplerosis in health and disease: food for thought. Cardiovascular Research. 90: 210-9. PMID 21398307 DOI: 10.1093/Cvr/Cvr055 |
0.356 |
|
2011 |
Jian B, Yang S, Chen D, Zou L, Chatham JC, Chaudry I, Raju R. Aging influences cardiac mitochondrial gene expression and cardiovascular function following hemorrhage injury. Molecular Medicine (Cambridge, Mass.). 17: 542-9. PMID 21193900 DOI: 10.2119/Molmed.2010.00195 |
0.301 |
|
2011 |
Marsh SA, Chatham JC. The paradoxical world of protein O-GlcNAcylation: a novel effector of cardiovascular (dys)function. Cardiovascular Research. 89: 487-8. PMID 21177335 DOI: 10.1093/Cvr/Cvq405 |
0.46 |
|
2011 |
Marsh SA, Dell'Italia LJ, Chatham JC. Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice. Amino Acids. 40: 819-28. PMID 20676904 DOI: 10.1007/S00726-010-0699-8 |
0.425 |
|
2011 |
Lauzier B, Bouchard B, Vaillant F, Labarthe F, Daneault C, Robillard-Frayne I, Thompson-Legault J, Gélinas R, Chatham J, Des Rosiers C. 256 The metabolic effects of glutamine in the heart beyond anaplerosis: role of the hexosamine biosynthetic pathway Archives of Cardiovascular Diseases Supplements. 3: 84. DOI: 10.1016/S1878-6480(11)70258-0 |
0.39 |
|
2010 |
Chatham JC, Marchase RB. Protein O-GlcNAcylation: A critical regulator of the cellular response to stress. Current Signal Transduction Therapy. 5: 49-59. PMID 22308107 DOI: 10.2174/157436210790226492 |
0.5 |
|
2010 |
Laczy B, Marsh SA, Brocks CA, Wittmann I, Chatham JC. Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1715-27. PMID 20833964 DOI: 10.1152/Ajpheart.00337.2010 |
0.5 |
|
2010 |
Teo CF, Ingale S, Wolfert MA, Elsayed GA, Nöt LG, Chatham JC, Wells L, Boons GJ. Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc. Nature Chemical Biology. 6: 338-43. PMID 20305658 DOI: 10.1038/Nchembio.338 |
0.381 |
|
2010 |
Wang P, Liu J, Li Y, Wu S, Luo J, Yang H, Subbiah R, Chatham J, Zhelyabovska O, Yang Q. Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart. Circulation Research. 106: 911-9. PMID 20075336 DOI: 10.1161/Circresaha.109.206185 |
0.347 |
|
2010 |
Nöt LG, Brocks CA, Vámhidy L, Marchase RB, Chatham JC. Increased O-linked beta-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats. Critical Care Medicine. 38: 562-71. PMID 20016375 DOI: 10.1097/Ccm.0B013E3181Cb10B3 |
0.436 |
|
2010 |
Chatham JC, Marchase RB. The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses. Biochimica Et Biophysica Acta. 1800: 57-66. PMID 19607882 DOI: 10.1016/J.Bbagen.2009.07.004 |
0.533 |
|
2009 |
Hill BG, Dranka BP, Zou L, Chatham JC, Darley-Usmar VM. Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal. The Biochemical Journal. 424: 99-107. PMID 19740075 DOI: 10.1042/Bj20090934 |
0.322 |
|
2009 |
Degrell P, Cseh J, Mohás M, Molnár GA, Pajor L, Chatham JC, Fülöp N, Wittmann I. Evidence of O-linked N-acetylglucosamine in diabetic nephropathy. Life Sciences. 84: 389-93. PMID 19302818 DOI: 10.1016/J.Lfs.2009.01.007 |
0.438 |
|
2009 |
Zou L, Yang S, Champattanachai V, Hu S, Chaudry IH, Marchase RB, Chatham JC. Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling. American Journal of Physiology. Heart and Circulatory Physiology. 296: H515-23. PMID 19098112 DOI: 10.1152/Ajpheart.01025.2008 |
0.449 |
|
2009 |
Laczy B, Hill BG, Wang K, Paterson AJ, White CR, Xing D, Chen YF, Darley-Usmar V, Oparil S, Chatham JC. Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system. American Journal of Physiology. Heart and Circulatory Physiology. 296: H13-28. PMID 19028792 DOI: 10.1152/Ajpheart.01056.2008 |
0.527 |
|
2008 |
Xing D, Feng W, Nöt LG, Miller AP, Zhang Y, Chen YF, Majid-Hassan E, Chatham JC, Oparil S. Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury. American Journal of Physiology. Heart and Circulatory Physiology. 295: H335-42. PMID 18469144 DOI: 10.1152/Ajpheart.01259.2007 |
0.333 |
|
2008 |
Champattanachai V, Marchase RB, Chatham JC. Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2. American Journal of Physiology. Cell Physiology. 294: C1509-20. PMID 18367586 DOI: 10.1152/Ajpcell.00456.2007 |
0.481 |
|
2008 |
Fülöp N, Feng W, Xing D, He K, Not LG, Brocks CA, Marchase RB, Miller AP, Chatham JC. Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats. Biogerontology. 9: 139-51. PMID 18185980 DOI: 10.1007/S10522-007-9123-5 |
0.491 |
|
2008 |
Shan D, Marchase RB, Chatham JC. Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes. American Journal of Physiology. Cell Physiology. 294: C833-41. PMID 18184877 DOI: 10.1152/Ajpcell.00313.2007 |
0.351 |
|
2008 |
Chatham JC, Nöt LG, Fülöp N, Marchase RB. Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma. Shock (Augusta, Ga.). 29: 431-40. PMID 17909453 DOI: 10.1097/Shk.0B013E3181598Bad |
0.526 |
|
2008 |
Cseh J, Degrell P, Fulop N, Pajor L, Chatham JC, Wittmann I. O-Glycosylation is Increased in the Tubuli and Glomeruli of Patients with Diabetic Nephropathy. The Faseb Journal. 22: 160-160. DOI: 10.1096/Fasebj.22.2_Supplement.160 |
0.387 |
|
2007 |
Liu J, Marchase RB, Chatham JC. Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1391-9. PMID 17573462 DOI: 10.1152/Ajpheart.00285.2007 |
0.525 |
|
2007 |
Nöt LG, Marchase RB, Fülöp N, Brocks CA, Chatham JC. Glucosamine administration improves survival rate after severe hemorrhagic shock combined with trauma in rats. Shock (Augusta, Ga.). 28: 345-52. PMID 17545939 DOI: 10.1097/Shk.0B013E3180487Ebb |
0.417 |
|
2007 |
Zou L, Yang S, Hu S, Chaudry IH, Marchase RB, Chatham JC. The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels. Shock (Augusta, Ga.). 27: 402-8. PMID 17414423 DOI: 10.1097/01.Shk.0000245031.31859.29 |
0.44 |
|
2007 |
Fülöp N, Zhang Z, Marchase RB, Chatham JC. Glucosamine cardioprotection in perfused rat hearts associated with increased O-linked N-acetylglucosamine protein modification and altered p38 activation. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2227-36. PMID 17208994 DOI: 10.1152/Ajpheart.01091.2006 |
0.486 |
|
2007 |
Wang P, Fraser H, Lloyd SG, McVeigh JJ, Belardinelli L, Chatham JC. A comparison between ranolazine and CVT-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion. The Journal of Pharmacology and Experimental Therapeutics. 321: 213-20. PMID 17202401 DOI: 10.1124/Jpet.106.115519 |
0.331 |
|
2007 |
Fülöp N, Mason MM, Dutta K, Wang P, Davidoff AJ, Marchase RB, Chatham JC. Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart. American Journal of Physiology. Cell Physiology. 292: C1370-8. PMID 17135297 DOI: 10.1152/Ajpcell.00422.2006 |
0.47 |
|
2007 |
Liu J, Marchase RB, Chatham JC. Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels. Journal of Molecular and Cellular Cardiology. 42: 177-85. PMID 17069847 DOI: 10.1016/J.Yjmcc.2006.09.015 |
0.539 |
|
2007 |
Fülöp N, Marchase RB, Chatham JC. Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system. Cardiovascular Research. 73: 288-97. PMID 16970929 DOI: 10.1016/J.Cardiores.2006.07.018 |
0.534 |
|
2007 |
Champattanachai V, Marchase RB, Chatham JC. Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc. American Journal of Physiology. Cell Physiology. 292: C178-87. PMID 16899550 DOI: 10.1152/Ajpcell.00162.2006 |
0.518 |
|
2007 |
Miller AP, Robertson C, Xing D, Li P, Chen YF, Chatham JC, Oparil S. 197 Aging-Related Accumulation Of O-Glcnacylated Proteins In The Cardiovascular System. Journal of Investigative Medicine. 55. DOI: 10.1097/00042871-200701010-00711 |
0.453 |
|
2007 |
Fülöp N, Onay-Besikci A, Marchase RB, Chatham JC. Regulation of cardiac substrate utilization by protein O-glycosylation Journal of Molecular and Cellular Cardiology. 42: S64. DOI: 10.1016/J.Yjmcc.2007.03.788 |
0.472 |
|
2006 |
Yang S, Zou LY, Bounelis P, Chaudry I, Chatham JC, Marchase RB. Glucosamine administration during resuscitation improves organ function after trauma hemorrhage. Shock (Augusta, Ga.). 25: 600-7. PMID 16721268 DOI: 10.1097/01.Shk.0000209563.07693.Db |
0.459 |
|
2006 |
Liu J, Pang Y, Chang T, Bounelis P, Chatham JC, Marchase RB. Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia. Journal of Molecular and Cellular Cardiology. 40: 303-12. PMID 16337959 DOI: 10.1016/J.Yjmcc.2005.11.003 |
0.515 |
|
2006 |
Nagy T, Champattanachai V, Marchase RB, Chatham JC. Glucosamine inhibits angiotensin II-induced cytoplasmic Ca2+ elevation in neonatal cardiomyocytes via protein-associated O-linked N-acetylglucosamine. American Journal of Physiology. Cell Physiology. 290: C57-65. PMID 16107505 DOI: 10.1152/Ajpcell.00263.2005 |
0.489 |
|
2005 |
Des Rosiers C, Chatham JC. Myocardial phenotyping using isotopomer analysis of metabolic fluxes Biochemical Society Transactions. 33: 1413-1417. PMID 16246133 DOI: 10.1042/Bst0331413 |
0.322 |
|
2005 |
Wang P, Lloyd SG, Chatham JC. Impact of high glucose/high insulin and dichloroacetate treatment on carbohydrate oxidation and functional recovery after low-flow ischemia and reperfusion in the isolated perfused rat heart. Circulation. 111: 2066-72. PMID 15824201 DOI: 10.1161/01.Cir.0000162466.06150.D4 |
0.382 |
|
2005 |
Wang P, Lloyd SG, Zeng H, Bonen A, Chatham JC. Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2102-10. PMID 15615844 DOI: 10.1152/Ajpheart.00935.2004 |
0.376 |
|
2004 |
Lloyd SG, Zeng H, Wang P, Chatham JC. Lactate isotopomer analysis by 1H NMR spectroscopy: consideration of long-range nuclear spin-spin interactions. Magnetic Resonance in Medicine. 51: 1279-82. PMID 15170850 DOI: 10.1002/Mrm.20075 |
0.303 |
|
2004 |
Pang Y, Bounelis P, Chatham JC, Marchase RB. Hexosamine pathway is responsible for inhibition by diabetes of phenylephrine-induced inotropy. Diabetes. 53: 1074-81. PMID 15047624 DOI: 10.2337/Diabetes.53.4.1074 |
0.385 |
|
2004 |
Des Rosiers C, Lloyd S, Comte B, Chatham JC. A critical perspective of the use of (13)C-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism. Metabolic Engineering. 6: 44-58. PMID 14734255 DOI: 10.1016/J.Ymben.2003.10.004 |
0.317 |
|
2004 |
Wang P, Chatham JC. Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart. American Journal of Physiology. Endocrinology and Metabolism. 286: E725-36. PMID 14722022 DOI: 10.1152/Ajpendo.00295.2003 |
0.329 |
|
2004 |
Bounelis P, Liu J, Pang Y, Chatham JC, Marchase RB. GLUCOSAMINE PROVIDES PROTECTION FROM ISCHEMIA/REPERFUSION INJURY AND CALCIUM OVERLOAD IN ISOLATED HEARTS AND LEADS TO AN INCREASE IN O-LINKED GLYCOSYLATION Shock. 21: 58. DOI: 10.1097/00024382-200406002-00170 |
0.422 |
|
2003 |
Lloyd S, Brocks C, Chatham JC. Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart. American Journal of Physiology. Heart and Circulatory Physiology. 285: H163-72. PMID 12793977 DOI: 10.1152/Ajpheart.01117.2002 |
0.352 |
|
2002 |
Chatham JC. Lactate -- the forgotten fuel! The Journal of Physiology. 542: 333. PMID 12122132 DOI: 10.1113/Jphysiol.2002.020974 |
0.367 |
|
2002 |
Chatham JC, Seymour AM. Cardiac carbohydrate metabolism in Zucker diabetic fatty rats. Cardiovascular Research. 55: 104-12. PMID 12062713 DOI: 10.1016/S0008-6363(02)00399-1 |
0.377 |
|
2002 |
Weiss RG, Chatham JC, Georgakopolous D, Charron MJ, Wallimann T, Kay L, Walzel B, Wang Y, Kass DA, Gerstenblith G, Chacko VP. An increase in the myocardial PCr/ATP ratio in GLUT4 null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 613-5. PMID 11919171 DOI: 10.1096/Fj.01-0462Fje |
0.341 |
|
2002 |
Wang P, Chatham JC. 08 Altered substrate provision and cardiac function during ischemia and reperfusion Journal of Molecular and Cellular Cardiology. 34. DOI: 10.1016/S0022-2828(02)90156-2 |
0.326 |
|
2002 |
Pang Y, Hunton DL, Chatham J, Marchase RB. 24 Hyperglycemia inhibitis capacitative Ca2+ entry and hypertrophy in cardiomyocytes Journal of Molecular and Cellular Cardiology. 34: A16. DOI: 10.1016/S0022-2828(02)90130-6 |
0.335 |
|
2001 |
Chatham JC, Des Rosiers C, Forder JR. Evidence of separate pathways for lactate uptake and release by the perfused rat heart American Journal of Physiology - Endocrinology and Metabolism. 281. PMID 11551857 DOI: 10.1152/Ajpendo.2001.281.4.E794 |
0.38 |
|
2001 |
Hall JL, Chatham JC, Eldar-Finkelman H, Gibbons GH. Upregulation of glucose metabolism during intimal lesion formation is coupled to the inhibition of vascular smooth muscle cell apoptosis. Role of GSK3beta. Diabetes. 50: 1171-9. PMID 11334423 DOI: 10.2337/Diabetes.50.5.1171 |
0.35 |
|
2001 |
Chatham J. The impact of type 2 diabetes on the regulation of cardiac energy metabolism and function Journal of Molecular and Cellular Cardiology. 33. DOI: 10.1016/S0022-2828(01)90587-5 |
0.339 |
|
2001 |
Chatham J, Seymour A. Cardiac carbohydrate metabolism in hearts from normal and type-2 diabetic rats Journal of Molecular and Cellular Cardiology. 33. DOI: 10.1016/S0022-2828(01)90075-6 |
0.352 |
|
2000 |
Stenbit AE, Katz EB, Chatham JC, Geenen DL, Factor SM, Weiss RG, Tsao TS, Malhotra A, Chacko VP, Ocampo C, Jelicks LA, Charron MJ. Preservation of glucose metabolism in hypertrophic GLUT4-null hearts American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 10899071 DOI: 10.1152/Ajpheart.2000.279.1.H313 |
0.376 |
|
1999 |
Chatham JC, Gao ZP, Bonen A, Forder JR. Preferential inhibition of lactate oxidation relative to glucose oxidation in the rat heart following diabetes Cardiovascular Research. 43: 96-106. PMID 10536694 DOI: 10.1016/S0008-6363(99)00056-5 |
0.353 |
|
1999 |
Chatham JC, Gao ZP, Forder JR. Impact of 1 wk of diabetes on the regulation of myocardial carbohydrate and fatty acid oxidation American Journal of Physiology - Endocrinology and Metabolism. 277. PMID 10444431 DOI: 10.1152/Ajpendo.1999.277.2.E342 |
0.32 |
|
1997 |
Seymour AML, Chatham JC. The effects of hypertrophy and diabetes on cardiac pyruvate dehydrogenase activity Journal of Molecular and Cellular Cardiology. 29: 2771-2778. PMID 9344771 DOI: 10.1006/Jmcc.1997.0512 |
0.348 |
|
1997 |
Chatham JC, Forder JR. Relationship between cardiac function and substrate oxidation in hearts of diabetic rats American Journal of Physiology - Heart and Circulatory Physiology. 42. DOI: 10.1152/Ajpheart.1997.273.1.H52 |
0.374 |
|
1996 |
Tielens ET, Forder JR, Chatham JC, Marrelli SP, Ladenson PW. Acute L-triiodothyronine administration potentiates inotropic responses to β-adrenergic stimulation in the isolated perfused rat heart Cardiovascular Research. 32: 306-310. PMID 8796117 DOI: 10.1016/0008-6363(96)00096-X |
0.318 |
|
1996 |
Chatham JC, Forder JR. Metabolic compartmentation of lactate in the glucose-perfused rat heart American Journal of Physiology - Heart and Circulatory Physiology. 270. PMID 8769755 DOI: 10.1152/Ajpheart.1996.270.1.H224 |
0.365 |
|
1995 |
Chatham JC, Forder JR, Glickson JD, Chance EM. Calculation of absolute metabolic flux and the elucidation of the pathways of glutamate labeling in perfused rat heart by 13C NMR spectroscopy and nonlinear least squares analysis. The Journal of Biological Chemistry. 270: 7999-8008. PMID 7713900 DOI: 10.1074/Jbc.270.14.7999 |
0.309 |
|
1993 |
Chatham JC, Forder JR. A 13C-NMR study of glucose oxidation in the intact functioning rat heart following diabetes-induced cardiomyopathy Journal of Molecular and Cellular Cardiology. 25: 1203-1213. PMID 8263954 DOI: 10.1006/Jmcc.1993.1133 |
0.385 |
|
1992 |
Chatham JC, Hutchins GM, Glickson JD. Altered glucose metabolism in adriamycin-induced heart failure. Biochimica Et Biophysica Acta. 1138: 1-5. PMID 1346573 DOI: 10.1016/0925-4439(92)90143-B |
0.365 |
|
1992 |
Forder JR, Chatham JC, Glickson JD. Consequences of chronic adriamycin treatment on cardiac function and metabolism Journal of Molecular and Cellular Cardiology. 24: 125. DOI: 10.1016/0022-2828(92)90402-L |
0.314 |
|
1992 |
Forder JR, Chatham JC, Glickson JD. Myocardial glucose metabolism is altered in the rat heart by : Detection by 1H-, 13C- and 31P-NMR spectroscopy Journal of Molecular and Cellular Cardiology. 24: 83. DOI: 10.1016/0022-2828(92)90275-5 |
0.344 |
|
1990 |
Chatham JC, Blackband SJ. 31P chemical shift imaging of the regionally ischemic perfused heart. Nmr in Biomedicine. 3: 190-3. PMID 2206851 DOI: 10.1002/Nbm.1940030408 |
0.33 |
|
1990 |
Chatham JC, Cousins JP, Glickson JD. The relationship between cardiac function and metabolism in acute adriamycin-treated perfused rat hearts studied by 31P and 13C NMR spectroscopy. Journal of Molecular and Cellular Cardiology. 22: 1187-97. PMID 2095440 DOI: 10.1016/0022-2828(90)90082-D |
0.347 |
|
1989 |
Chatham JC, Gilbert HF, Radda GK. The metabolic consequences of hydroperoxide perfusion on the isolated rat heart European Journal of Biochemistry. 184: 657-662. PMID 2806248 DOI: 10.1111/J.1432-1033.1989.Tb15063.X |
0.315 |
|
1988 |
Chatham JC, Seymour AML, Harmsen E, Radda GK. Depletion of myocardial glutathione: Its effects on heart function and metabolism during ischaemia and reperfusion Cardiovascular Research. 22: 833-839. PMID 3256425 DOI: 10.1093/Cvr/22.11.833 |
0.362 |
|
1988 |
Chatham J, Gilbert HF, Radda GK. Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. Febs Letters. 238: 445-9. PMID 3169268 DOI: 10.1016/0014-5793(88)80529-5 |
0.366 |
|
1985 |
Chatham JC, Challiss RAJ, Radda GK, Seymour AML. Studies of the protective effect of ribose in myocardial ischaemia by using 31P-nuclear-magnetic-resonance spectroscopy Biochemical Society Transactions. 13: 885-886. DOI: 10.1042/Bst0130885 |
0.333 |
|
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