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Elizabeth A. Leadbetter, Ph.D. - Publications

Affiliations: 
2002 Boston University, Boston, MA, United States 
Area:
Immunology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hägglöf T, Parthasarathy R, Liendo N, Dudley EA, Leadbetter EA. RIPK1 deficiency prevents thymic NK1.1 expression and subsequent iNKT cell development. Frontiers in Immunology. 14: 1103591. PMID 37965338 DOI: 10.3389/fimmu.2023.1103591  0.441
2022 Hägglöf T, Vanz C, Kumagai A, Dudley E, Ortega V, Siller M, Parthasarathy R, Keegan J, Koenigs A, Shute T, Leadbetter EA. T-bet B cells accumulate in adipose tissue and exacerbate metabolic disorder during obesity. Cell Metabolism. PMID 35868310 DOI: 10.1016/j.cmet.2022.07.002  0.366
2021 Parthasarathy R, Hägglöf T, Hadley JT, McLennan A, Mattke A, Dudley EA, Kumagai A, Dong LQ, Leadbetter EA. Receptor Interacting Protein Kinase Pathways Regulate Innate B Cell Developmental Checkpoints But Not Effector Function in Mice. Frontiers in Immunology. 12: 758407. PMID 34956189 DOI: 10.3389/fimmu.2021.758407  0.461
2021 Shou Y, Koroleva E, Spencer CM, Shein SA, Korchagina AA, Yusoof KA, Parthasarathy R, Leadbetter EA, Akopian AN, Muñoz AR, Tumanov AV. Redefining the Role of Lymphotoxin Beta Receptor in the Maintenance of Lymphoid Organs and Immune Cell Homeostasis in Adulthood. Frontiers in Immunology. 12: 712632. PMID 34335629 DOI: 10.3389/fimmu.2021.712632  0.339
2021 Shute T, Amiel E, Alam N, Yates JL, Mohrs K, Dudley E, Salas B, Mesa C, Serrata A, Angel D, Vincent BK, Weyers A, Lanthier PA, Vomhof-Dekrey E, Fromme R, ... ... Leadbetter EA, et al. Glycolipid-Containing Nanoparticle Vaccine Engages Invariant NKT Cells to Enhance Humoral Protection against Systemic Bacterial Infection but Abrogates T-Independent Vaccine Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 33811104 DOI: 10.4049/jimmunol.2001283  0.456
2021 Leadbetter EA, Karlsson MCI. Invariant natural killer T cells balance B cell immunity. Immunological Reviews. PMID 33438287 DOI: 10.1111/imr.12938  0.535
2021 Leadbetter EA, Karlsson MCI. Reading the room: iNKT cells influence B cell responses. Molecular Immunology. 130: 49-54. PMID 33360376 DOI: 10.1016/j.molimm.2020.12.005  0.529
2020 Sedimbi SK, Hägglöf T, Garimella MG, Wang S, Duhlin A, Coelho A, Ingelshed K, Mondoc E, Malin SG, Holmdahl R, Lane DP, Leadbetter EA, Karlsson MCI. Combined proinflammatory cytokine and cognate activation of invariant natural killer T cells enhances anti-DNA antibody responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 32295878 DOI: 10.1073/Pnas.1920463117  0.646
2018 Lin JS, Mohrs K, Szaba FM, Kummer LW, Leadbetter EA, Mohrs M. Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection. Mucosal Immunology. PMID 30361537 DOI: 10.1038/S41385-018-0100-X  0.431
2018 Yates JL, Leadbetter E, Mantis NJ. Alpha-galactosylceramide (αGalCer) Enhances Vaccine-induced Protection in a Model of Ricin Intoxication. Human Vaccines & Immunotherapeutics. 1-14. PMID 29617191 DOI: 10.1080/21645515.2018.1461299  0.308
2017 King IL, Mohrs K, Meli AP, Downey J, Lanthier P, Tzelepis F, Fritz JH, Tumanov AV, Divangahi M, Leadbetter EA, Mohrs M. Intestinal helminth infection impacts the systemic distribution and function of the naive lymphocyte pool. Mucosal Immunology. PMID 28120841 DOI: 10.1038/Mi.2016.127  0.446
2016 Hägglöf T, Sedimbi SK, Yates JL, Parsa R, Salas BH, Harris RA, Leadbetter EA, Karlsson MC. Neutrophils license iNKT cells to regulate self-reactive mouse B cell responses. Nature Immunology. PMID 27798616 DOI: 10.1038/Ni.3583  0.602
2015 Vomhof-DeKrey EE, Yates J, Hägglöf T, Lanthier P, Amiel E, Veerapen N, Besra GS, Karlsson MC, Leadbetter EA. Cognate interaction with iNKT cells expands IL-10-producing B regulatory cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 12474-9. PMID 26392556 DOI: 10.1073/Pnas.1504790112  0.611
2015 Lynch L, Michelet X, Zhang S, Brennan PJ, Moseman A, Lester C, Besra G, Vomhof-Dekrey EE, Tighe M, Koay HF, Godfrey DI, Leadbetter EA, Sant'Angelo DB, von Andrian U, Brenner MB. Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue. Nature Immunology. 16: 85-95. PMID 25436972 DOI: 10.1038/Ni.3047  0.595
2014 Siegmann N, Worbs D, Effinger F, Bormann T, Gebhardt M, Ulrich M, Wermeling F, Müller-Hermelink E, Biedermann T, Tighe M, Edwards MJ, Caldwell C, Leadbetter E, Karlsson MC, Becker KA, et al. Invariant natural killer T (iNKT) cells prevent autoimmunity, but induce pulmonary inflammation in cystic fibrosis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 56-70. PMID 24977481 DOI: 10.1159/000362984  0.311
2014 Vomhof-DeKrey EE, Yates J, Leadbetter EA. Invariant NKT cells provide innate and adaptive help for B cells. Current Opinion in Immunology. 28: 12-7. PMID 24514004 DOI: 10.1016/J.Coi.2014.01.007  0.605
2013 King IL, Amiel E, Tighe M, Mohrs K, Veerapen N, Besra G, Mohrs M, Leadbetter EA. The mechanism of splenic invariant NKT cell activation dictates localization in vivo. Journal of Immunology (Baltimore, Md. : 1950). 191: 572-82. PMID 23785119 DOI: 10.4049/Jimmunol.1300299  0.564
2012 Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C. SAP expression in invariant NKT cells is required for cognate help to support B-cell responses. Blood. 120: 122-9. PMID 22613797 DOI: 10.1182/Blood-2011-11-395913  0.638
2012 King IL, Fortier A, Tighe M, Dibble J, Watts GF, Veerapen N, Haberman AM, Besra GS, Mohrs M, Brenner MB, Leadbetter EA. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nature Immunology. 13: 44-50. PMID 22120118 DOI: 10.1038/Ni.2172  0.697
2011 Brigl M, Tatituri RV, Watts GF, Bhowruth V, Leadbetter EA, Barton N, Cohen NR, Hsu FF, Besra GS, Brenner MB. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. The Journal of Experimental Medicine. 208: 1163-77. PMID 21555485 DOI: 10.1084/Jem.20102555  0.714
2010 Veerapen N, Leadbetter EA, Brenner MB, Cox LR, Besra GS. Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies. Bioconjugate Chemistry. 21: 741-7. PMID 20345125 DOI: 10.1021/Bc9005255  0.572
2008 Leadbetter EA, Brigl M, Illarionov P, Cohen N, Luteran MC, Pillai S, Besra GS, Brenner MB. NK T cells provide lipid antigen-specific cognate help for B cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 8339-44. PMID 18550809 DOI: 10.1073/Pnas.0801375105  0.731
2005 van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 437: 906-10. PMID 16208376 DOI: 10.1038/Nature04001  0.652
2005 William J, Euler C, Leadbetter E, Marshak-Rothstein A, Shlomchik MJ. Visualizing the onset and evolution of an autoantibody response in systemic autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 174: 6872-8. PMID 15905529 DOI: 10.4049/Jimmunol.174.11.6872  0.633
2005 Rifkin IR, Leadbetter EA, Busconi L, Viglianti G, Marshak-Rothstein A. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunological Reviews. 204: 27-42. PMID 15790348 DOI: 10.1111/J.0105-2896.2005.00239.X  0.574
2004 Marshak-Rothstein A, Busconi L, Lau CM, Tabor AS, Leadbetter EA, Akira S, Krieg AM, Lipford GB, Viglianti GA, Rifkin IR. Comparison of CpG s-ODNs, chromatin immune complexes, and dsDNA fragment immune complexes in the TLR9-dependent activation of rheumatoid factor B cells. Journal of Endotoxin Research. 10: 247-51. PMID 15373969 DOI: 10.1177/09680519040100040801  0.614
2003 Leadbetter EA, Rifkin IR, Marshak-Rothstein A. Toll-like receptors and activation of autoreactive B cells. Current Directions in Autoimmunity. 6: 105-22. PMID 12408049 DOI: 10.1159/000066858  0.637
2002 Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature. 416: 603-7. PMID 11948342 DOI: 10.1038/416603A  0.689
2000 Rifkin IR, Leadbetter EA, Beaudette BC, Kiani C, Monestier M, Shlomchik MJ, Marshak-Rothstein A. Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 1626-33. PMID 10903773 DOI: 10.4049/Jimmunol.165.3.1626  0.69
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