Michael E. Abram, Ph.D. - Publications

Affiliations: 
2005 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Microbiology Biology, Biochemistry

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ram RR, Duatschek P, Margot N, Abram M, Geleziunas R, Hesselgesser J, Callebaut C. Activation of HIV-specific CD8+ T-cells from HIV+ donors by vesatolimod. Antiviral Therapy. 25: 163-169. PMID 32420906 DOI: 10.3851/Imp3359  0.467
2020 Margot N, Ram R, Abram M, Haubrich R, Callebaut C. Antiviral Activity of Tenofovir Alafenamide against HIV-1 with Thymidine Analog-Associated Mutations and M184V. Antimicrobial Agents and Chemotherapy. 64. PMID 31988104 DOI: 10.1128/Aac.02557-19  0.594
2019 Margot NA, Ram RR, White KL, Abram ME, Callebaut C. Antiviral Activity of HIV-1 Integrase Strand Transfer Inhibitors against Mutants with Integrase Resistance-Associated Mutations and their Frequency in Treatment-Naïve Individuals. Journal of Medical Virology. PMID 31389026 DOI: 10.1002/Jmv.25564  0.496
2017 Margot NA, Wong P, Kulkarni R, White K, Porter D, Abram ME, Callebaut C, Miller MD. Commonly Transmitted HIV-1 Drug Resistance Mutations in Reverse-Transcriptase and Protease in Antiretroviral Treatment-Naive Patients and Response to Regimens Containing Tenofovir Disoproxil Fumarate or Tenofovir Alafenamide. The Journal of Infectious Diseases. 215: 920-927. PMID 28453836 DOI: 10.1093/Infdis/Jix015  0.486
2017 Margot NA, Wong P, Kulkarni R, White K, Porter D, Abram ME, Callebaut C, Miller MD. Commonly Transmitted HIV-1 Drug Resistance Mutations in Reverse Transcriptase and Protease in Antiretroviral Treatment-Naïve Patients do not Affect Response to Tenofovir Disoproxil Fumarate- or Tenofovir Alafenamide-Containing Regimens. The Journal of Infectious Diseases. PMID 28329343 DOI: 10.1093/infdis/jix015  0.408
2017 Post FA, Yazdanpanah Y, Schembri G, Lazzarin A, Reynes J, Maggiolo F, Yan M, Abram ME, Tran-Muchowski C, Cheng A, Rhee MS. Efficacy and safety of emtricitabine/tenofovir alafenamide (FTC/TAF) vs. emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) as a backbone for treatment of HIV-1 infection in virologically suppressed adults: subgroup analysis by third agent of a randomized, double-blind, active-controlled phase 3 trial(). Hiv Clinical Trials. 1-6. PMID 28303753 DOI: 10.1080/15284336.2017.1291867  0.41
2017 Raffi F, Orkin C, Clarke A, Slama L, Gallant J, Daar E, Henry K, Santana-Bagur J, Stein DK, Bellos N, Scarsella A, Yan M, Abram ME, Cheng A, Rhee MS. Long-term (96-week) Efficacy and Safety After Switching from Tenofovir Disoproxil Fumarate (TDF) to Tenofovir Alafenamide (TAF) in HIV-infected, Virologically Suppressed Adults. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 28272164 DOI: 10.1097/Qai.0000000000001344  0.492
2017 Abram ME, Ram RR, Margot NA, Barnes TL, White KL, Callebaut C, Miller MD. Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome. Plos One. 12: e0172206. PMID 28212411 DOI: 10.1371/Journal.Pone.0172206  0.5
2016 Post FA, Tebas P, Clarke A, Cotte L, Short W, Abram ME, Jiang S, Cheng A, Das M, Fordyce MW. Switching to Tenofovir Alafenamide, Coformulated With Elvitegravir, Cobicistat, and Emtricitabine, in HIV-Infected Adults With Renal Impairment: 96-Week Results From a Single-Arm, Multicenter, Open-Label Phase 3 Study. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27673443 DOI: 10.1097/Qai.0000000000001186  0.483
2016 Gallant JE, Daar ES, Raffi F, Brinson C, Ruane P, DeJesus E, Johnson M, Clumeck N, Osiyemi O, Ward D, Morales-Ramirez J, Yan M, Abram ME, Plummer A, Cheng AK, et al. Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate given as fixed-dose combinations containing emtricitabine as backbones for treatment of HIV-1 infection in virologically suppressed adults: a randomised, double-blind, active-controlled phase 3 trial. The Lancet. Hiv. 3: e158-65. PMID 27036991 DOI: 10.1016/S2352-3018(16)00024-2  0.398
2015 Pozniak A, Arribas JR, Gathe J, Gupta SK, Post FA, Bloch M, Avihingsanon A, Crofoot G, Benson P, Lichtenstein K, Ramgopal M, Chetchotisakd P, Custodio JM, Abram ME, Wei X, et al. Switching to tenofovir alafenamide, coformulated with elvitegravir, cobicistat, and emtricitabine, in HIV-infected patients with renal impairment: 48 week results from a single-arm, multi-center, open-label, Phase 3 study. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26627107 DOI: 10.1097/Qai.0000000000000908  0.403
2015 Gallant JE, Koenig E, Andrade-Villanueva JF, Chetchotisakd P, DeJesus E, Antunes F, Arastéh K, Rizzardini G, Fehr J, Liu HC, Abram ME, Cao H, Szwarcberg J. Brief Report: Cobicistat Compared With Ritonavir as a Pharmacoenhancer for Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate: Week 144 Results. Journal of Acquired Immune Deficiency Syndromes (1999). 69: 338-40. PMID 26181707 DOI: 10.1097/Qai.0000000000000598  0.351
2015 Andreatta K, Kulkarni R, Abram ME, Nguyen T, Cao H, Miller MD, White KL. Baseline antiretroviral resistance mutations and treatment-emergent resistance in HIV-1 RNA-suppressed patients switching to EVG/COBI/FTC/TDF or continuing on their PI-, NNRTI-, or RAL-based regimen. Journal of Acquired Immune Deficiency Syndromes (1999). 68: 519-26. PMID 25559592 DOI: 10.1097/Qai.0000000000000503  0.526
2015 Post FA, Winston J, Andrade-Villanueva JF, Fisher M, Liu Y, Beraud C, Abram ME, Graham H, Rhee MS, Cheng AK, Szwarcberg J. Elvitegravir/cobicistat/emtricitabine/tenofovir DF in HIV-infected patients with mild-to-moderate renal impairment. Journal of Acquired Immune Deficiency Syndromes (1999). 68: 310-3. PMID 25469527 DOI: 10.1097/Qai.0000000000000476  0.396
2015 Abram ME, Tsiang M, White KL, Callebaut C, Miller MD. A cell-based strategy to assess intrinsic inhibition efficiencies of HIV-1 reverse transcriptase inhibitors. Antimicrobial Agents and Chemotherapy. 59: 838-48. PMID 25403670 DOI: 10.1128/Aac.04163-14  0.46
2014 McDonald CK, Martorell C, Ramgopal M, Laplante F, Fisher M, Post FA, Liu Y, Curley J, Abram ME, Custodio J, Graham H, Rhee MS, Szwarcberg J. Cobicistat-boosted protease inhibitors in HIV-infected patients with mild to moderate renal impairment. Hiv Clinical Trials. 15: 269-73. PMID 25433666 DOI: 10.1310/Hct1506-269  0.441
2014 Kulkarni R, Abram ME, McColl DJ, Barnes T, Fordyce MW, Szwarcberg J, Cheng AK, Miller MD, White KL. Week 144 resistance analysis of elvitegravir/cobicistat/emtricitabine/tenofovir DF versus atazanavir+ritonavir+emtricitabine/tenofovir DF in antiretroviral-naïve patients. Hiv Clinical Trials. 15: 218-30. PMID 25350960 DOI: 10.1310/Hct1504-218  0.521
2014 Abram ME, Ferris AL, Das K, Quinoñes O, Shao W, Tuske S, Alvord WG, Arnold E, Hughes SH. Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication. Journal of Virology. 88: 7589-601. PMID 24760888 DOI: 10.1128/Jvi.00302-14  0.542
2013 Abram ME, Hluhanich RM, Goodman DD, Andreatta KN, Margot NA, Ye L, Niedziela-Majka A, Barnes TL, Novikov N, Chen X, Svarovskaia ES, McColl DJ, White KL, Miller MD. Impact of primary elvitegravir resistance-associated mutations in HIV-1 integrase on drug susceptibility and viral replication fitness. Antimicrobial Agents and Chemotherapy. 57: 2654-63. PMID 23529738 DOI: 10.1128/Aac.02568-12  0.532
2013 Rockstroh JK, DeJesus E, Henry K, Molina JM, Gathe J, Ramanathan S, Wei X, Plummer A, Abram M, Cheng AK, Fordyce MW, Szwarcberg J. A randomized, double-blind comparison of coformulated elvitegravir/cobicistat/emtricitabine/tenofovir DF vs ritonavir-boosted atazanavir plus coformulated emtricitabine and tenofovir DF for initial treatment of HIV-1 infection: analysis of week 96 results. Journal of Acquired Immune Deficiency Syndromes (1999). 62: 483-6. PMID 23337366 DOI: 10.1097/Qai.0B013E318286415C  0.458
2010 Abram ME, Ferris AL, Shao W, Alvord WG, Hughes SH. Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication. Journal of Virology. 84: 9864-78. PMID 20660205 DOI: 10.1128/Jvi.00915-10  0.542
2010 Abram ME, Sarafianos SG, Parniak MA. The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site. Retrovirology. 7: 6. PMID 20122159 DOI: 10.1186/1742-4690-7-6  0.626
2005 Abram ME, Parniak MA. Virion instability of human immunodeficiency virus type 1 reverse transcriptase (RT) mutated in the protease cleavage site between RT p51 and the RT RNase H domain. Journal of Virology. 79: 11952-61. PMID 16140771 DOI: 10.1128/Jvi.79.18.11952-11961.2005  0.651
2004 Sluis-Cremer N, Arion D, Abram ME, Parniak MA. Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation. The International Journal of Biochemistry & Cell Biology. 36: 1836-47. PMID 15183348 DOI: 10.1016/J.Biocel.2004.02.020  0.626
2002 Arion D, Sluis-Cremer N, Min KL, Abram ME, Fletcher RS, Parniak MA. Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones. The Journal of Biological Chemistry. 277: 1370-4. PMID 11684697 DOI: 10.1074/jbc.M110254200  0.599
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