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Elena Y. Bryleva, Ph.D. - Publications

Affiliations: 
2008 Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Cell Biology
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Shibuya Y, Niu Z, Bryleva EY, Harris BT, Murphy SR, Kheirollah A, Bowen ZD, Chang CC, Chang TY. Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage. Neurobiology of Aging. 36: 2248-59. PMID 25930235 DOI: 10.1016/J.Neurobiolaging.2015.04.002  0.643
2014 Shibuya Y, Chang CC, Huang LH, Bryleva EY, Chang TY. Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14484-501. PMID 25339759 DOI: 10.1523/Jneurosci.2567-14.2014  0.602
2013 Murphy SR, Chang CC, Dogbevia G, Bryleva EY, Bowen Z, Hasan MT, Chang TY. Acat1 knockdown gene therapy decreases amyloid-β in a mouse model of Alzheimer's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1497-506. PMID 23774792 DOI: 10.1038/Mt.2013.118  0.638
2012 Rogers MA, Liu J, Kushnir MM, Bryleva E, Rockwood AL, Meikle AW, Shapiro D, Vaisman BL, Remaley AT, Chang CC, Chang TY. Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase. The Journal of Biological Chemistry. 287: 17483-92. PMID 22474282 DOI: 10.1074/Jbc.M111.331306  0.501
2010 Bryleva EY, Rogers MA, Chang CC, Buen F, Harris BT, Rousselet E, Seidah NG, Oddo S, LaFerla FM, Spencer TA, Hickey WF, Chang TY. ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proceedings of the National Academy of Sciences of the United States of America. 107: 3081-6. PMID 20133765 DOI: 10.1073/Pnas.0913828107  0.655
2010 Chang TY, Chang CC, Bryleva E, Rogers MA, Murphy SR. Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease. Iubmb Life. 62: 261-7. PMID 20101629 DOI: 10.1002/Iub.305  0.62
2010 Rogers M, Bryleva E, Chang C, Buen F, Harris B, Rousselet E, Seidah N, Oddo S, LaFerla F, Spencer T, Hickey W, Chang TY. P3-285: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in Alzheimer mice Alzheimer's & Dementia. 6: S535-S535. DOI: 10.1016/J.Jalz.2010.05.1785  0.58
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