Year |
Citation |
Score |
2023 |
Anderson CC, Bonney EA, Mueller TF, Corthay A, Havele C, Singh NJ, Øynebråten I, Bretscher PA. On antigen-specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation. Scandinavian Journal of Immunology. 98: e13311. PMID 38112131 DOI: 10.1111/sji.13311 |
0.308 |
|
2023 |
Bretscher P. What Determines the Class of Immunity an Antigen Induces? A Foundational Question Whose Rational Consideration Has Been Undermined by the Information Overload. Biology. 12. PMID 37759652 DOI: 10.3390/biology12091253 |
0.617 |
|
2022 |
Bretscher PA. Analyzing some concepts of immune regulation of the last three decades: Fostering greater research resilience despite the information overload. A personal view. Frontiers in Immunology. 13: 960742. PMID 36405696 DOI: 10.3389/fimmu.2022.960742 |
0.365 |
|
2020 |
Bretscher PA, Al-Yassin G, Anderson CC. On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia. Scandinavian Journal of Immunology. e12888. PMID 32281665 DOI: 10.1111/sji.12888 |
0.473 |
|
2019 |
Bretscher P. On Analyzing How the Th1/Th2 Phenotype of an Immune Response Is Determined: Classical Observations Must Not Be Ignored. Frontiers in Immunology. 10: 1234. PMID 31231378 DOI: 10.3389/Fimmu.2019.01234 |
0.403 |
|
2019 |
Bretscher PA, Al-Yassin GA. On how the immune system preferentially interacts with antigen-specific molecules bound to antigen over unbound molecules, with emphasis on B cell receptor signalling. Scandinavian Journal of Immunology. e12795. PMID 31148206 DOI: 10.1111/sji.12795 |
0.324 |
|
2019 |
Bretscher PA. The history of the two-signal model of lymphocyte activation: A personal perspective. Scandinavian Journal of Immunology. e12762. PMID 30825214 DOI: 10.1111/sji.12762 |
0.491 |
|
2018 |
Al-Yassin GA, Bretscher PA. Does T Cell Activation Require a Quorum of Lymphocytes? Journal of Immunology (Baltimore, Md. : 1950). 201: 2855-2861. PMID 30397169 DOI: 10.4049/jimmunol.1800805 |
0.535 |
|
2017 |
Bretscher P, Corthay A, Anderson CC, Dembic Z, Havele C, Nagy ZA, Øynebråten I. Immune class regulation and its medical significance Part II of a Report of a Workshop on Foundational Concepts of Immune Regulation. Scandinavian Journal of Immunology. PMID 28236642 DOI: 10.1111/sji.12525 |
0.574 |
|
2016 |
Anderson CC, Bretscher P, Corthay A, Dembic Z, Havele C, Nagy ZA, Øynebråten I. Immunological Tolerance. Part I of a Report of a Workshop on Foundational Concepts of Immune Regulation. Scandinavian Journal of Immunology. PMID 27885703 DOI: 10.1111/Sji.12500 |
0.509 |
|
2016 |
Bretscher PA. Is the framework of Cohn's "Tritope Model" for how T cell receptors recognize peptide/self MHC complexes and allo- MHC plausible? The framework of Tritope Model of TcR recognition. Scandinavian Journal of Immunology. PMID 26991815 DOI: 10.1111/sji.12421 |
0.309 |
|
2015 |
Bretscher PA. A Conversation with Cohn on the Activation of CD4 T Cells Scandinavian Journal of Immunology. 82: 147-159. PMID 25998043 DOI: 10.1111/sji.12315 |
0.591 |
|
2014 |
Rudulier CD, McKinstry KK, Al-Yassin GA, Kroeger DR, Bretscher PA. The number of responding CD4 T cells and the dose of antigen conjointly determine the TH1/TH2 phenotype by modulating B7/CD28 interactions. Journal of Immunology (Baltimore, Md. : 1950). 192: 5140-50. PMID 24752446 DOI: 10.4049/Jimmunol.1301691 |
0.788 |
|
2014 |
Bretscher PA. On the Mechanism Determining the Th1/Th2 Phenotype of an Immune Response, and its Pertinence to Strategies for the Prevention, and Treatment, of Certain Infectious Diseases Scandinavian Journal of Immunology. 79: 361-376. PMID 24684592 DOI: 10.1111/sji.12175 |
0.313 |
|
2014 |
Bretscher PA. The Activation and Inactivation of Mature CD4 T cells: A Case for Peripheral Self-Nonself Discrimination Scandinavian Journal of Immunology. 79: 348-360. PMID 24684567 DOI: 10.1111/sji.12173 |
0.597 |
|
2013 |
Kroeger DR, Rudulier CD, Bretscher PA. Antigen presenting B cells facilitate CD4 T cell cooperation resulting in enhanced generation of effector and memory CD4 T cells. Plos One. 8: e77346. PMID 24155947 DOI: 10.1371/Journal.Pone.0077346 |
0.782 |
|
2012 |
Kroeger DR, Rudulier CD, Peters NC, Bretscher PA. Direct demonstration of CD4 T cell cooperation in the primary in vivo generation of CD4 effector T cells. International Immunology. 24: 519-27. PMID 22527289 DOI: 10.1093/Intimm/Dxs055 |
0.763 |
|
2012 |
Rudulier CD, Kroeger DR, Bretscher PA. Distinct roles of dendritic and B cells in the activation of naive CD4+ T cells. Immunotherapy. 4: 355-7. PMID 22512626 DOI: 10.2217/Imt.12.17 |
0.786 |
|
2012 |
Rudulier CD, Kroeger DR, Bretscher PA. The activation, by antigen, of naïve TCR transgenic CD4 T cells cultured at physiological, rather than artificially high, frequencies more accurately reflects the in vivo activation of normal numbers of naïve CD4(+) T cells. Cellular Immunology. 274: 115-20. PMID 22370222 DOI: 10.1016/J.Cellimm.2012.01.004 |
0.776 |
|
2010 |
Power C, Marfleet TW, Qualtiere L, Xiao W, Bretscher P. Development of Th1 imprints to rBCG expressing a foreign protein: implications for vaccination against HIV-1 and diverse influenza strains. Journal of Biomedicine & Biotechnology. 2010: 591348. PMID 20625498 DOI: 10.1155/2010/591348 |
0.33 |
|
2009 |
Hamilton D, Ismail N, Kroeger D, Rudulier C, Bretscher P. Macroimmunology and immunotherapy of cancer. Immunotherapy. 1: 367-83. PMID 20635957 DOI: 10.2217/Imt.09.6 |
0.708 |
|
2009 |
Peters NC, Kroeger DR, Mickelwright S, Bretscher PA. CD4 T cell cooperation is required for the in vivo activation of CD4 T cells. International Immunology. 21: 1213-24. PMID 19736293 DOI: 10.1093/Intimm/Dxp085 |
0.773 |
|
2006 |
Strutt TM, Uzonna J, McKinstry KK, Bretscher PA. Activation of thymic T cells by MHC alloantigen requires syngeneic, activated CD4+ T cells and B cells as APC. International Immunology. 18: 719-28. PMID 16569677 DOI: 10.1093/intimm/dxl009 |
0.579 |
|
2005 |
Ismail N, Basten A, Briscoe H, Bretscher PA. Increasing the foreignness of an antigen, by coupling a second and foreign antigen to it, increases the T helper type 2 component of the immune response to the first antigen. Immunology. 115: 34-41. PMID 15819695 DOI: 10.1111/J.1365-2567.2005.02128.X |
0.522 |
|
2005 |
Strutt T, Bretscher P. Cooperation between CD4 T helper cells is required for the generation of alloantigen-specific, IFN-gamma-producing human CD4 T cells. Immunology and Cell Biology. 83: 175-81. PMID 15748214 DOI: 10.1111/J.1440-1711.2005.01306.X |
0.637 |
|
2005 |
Peters NC, Hamilton DH, Bretscher PA. Analysis of cytokine-producing Th cells from hen egg lysozyme-immunized mice reveals large numbers specific for "cryptic" peptides and different repertoires among different Th populations. European Journal of Immunology. 35: 56-65. PMID 15597327 DOI: 10.1002/Eji.200425581 |
0.698 |
|
2002 |
Bretscher P, Peters N. Two signal models of lymphocyte activation incorporate a mechanism of peripheral tolerance, and have implications for achieving immunological unresponsiveness and effective transplantation. Vox Sanguinis. 83: 155-8. PMID 12617128 DOI: 10.1111/J.1423-0410.2002.Tb05292.X |
0.621 |
|
2001 |
Uzonna JE, Wei G, Yurkowski D, Bretscher P. Immune elimination of Leishmania major in mice: Implications for immune memory, vaccination, and reactivation disease Journal of Immunology. 167: 6967-6974. PMID 11739516 DOI: 10.4049/Jimmunol.167.12.6967 |
0.354 |
|
2001 |
Ismail N, Bretscher PA. More antigen-dependent CD4+ T cell/CD4+ T cell interactions are required for the primary generation of Th2 than of Th1 cells European Journal of Immunology. 31: 1765-1771. PMID 11385621 DOI: 10.1002/1521-4141(200106)31:6<1765::AID-IMMU1765>3.0.CO;2-T |
0.577 |
|
2001 |
Bretscher PA, Ismail N, Peters N, Uzonna J. Cell-to-cell interactions and signaling within the immune system:Towards integrating mechanism and physiology Neuroimmune Biology. 1: 71-85. DOI: 10.1016/S1567-7443(01)80009-0 |
0.67 |
|
2000 |
Bretscher P. Contemporary models for peripheral tolerance and the classical 'historical postulate' Seminars in Immunology. 12: 221-229. PMID 10910743 DOI: 10.1006/Smim.2000.0235 |
0.453 |
|
1999 |
Power CA, Grand CL, Ismail N, Peters NC, Yurkowski DP, Bretscher PA. A valid ELISPOT assay for enumeration of ex vivo, antigen-specific, IFNgamma-producing T cells. Journal of Immunological Methods. 227: 99-107. PMID 10485258 DOI: 10.1016/S0022-1759(99)00074-5 |
0.71 |
|
1999 |
Bretscher PA. A two-step, two-signal model for the primary activation of precursor helper T cells Proceedings of the National Academy of Sciences of the United States of America. 96: 185-190. PMID 9874793 DOI: 10.1073/pnas.96.1.185 |
0.423 |
|
1997 |
Bretscher PA, Ogunremi O, Menon JN. Distinct immunological states in murine cutaneous leishmaniasis by immunising with different amounts of antigen: the generation of beneficial, potentially harmful, harmful and potentially extremely harmful states. Behring Institute Mitteilungen. 153-9. PMID 9382736 |
0.302 |
|
1992 |
Tuttosi S, Bretscher PA. Antigen-specific CD8+ T cells switch the immune response induced by antigen from AN IgG to a cell-mediated mode Journal of Immunology. 148: 397-403. PMID 1729360 |
0.523 |
|
1992 |
Bretscher PA, Wei G, Menon JN, Bielefeldt-Ohmann H. Establishment of stable, cell-mediated immunity that makes 'susceptible' mice resistant to Leishmania major Science. 257: 539-542. PMID 1636090 |
0.305 |
|
1991 |
Bretscher PA. The regulatory functions of CD4+ and CD8+ T-cell subsets in immune class regulation Research in Immunology. 142: 45-50. PMID 1905414 DOI: 10.1016/0923-2494(91)90011-7 |
0.534 |
|
1991 |
Swain SL, Gajewski TF, Fitch FW, Locksley RM, Daynes RA, Araneo BA, Powrie F, Fowell D, McKnight AJ, Mason D, Romagnani S, Bretscher PA, Mosmann T. CD4+ T-cell subsets: Regulation of differentiation and function: Discussion Research in Immunology. 142: 68-79. |
0.51 |
|
1987 |
LeClercq SA, Bretscher PA. T cells expressing delayed-type hypersensitivity can be derived from a humorally immune lymphocyte population European Journal of Immunology. 17: 949-954. PMID 3497043 |
0.455 |
|
1986 |
Bretscher PA. A cascade of T-T interactions, mediated by the linked recognition of antigen, in the induction of T cells able to help delayed-type hypersensitivity responses Journal of Immunology. 137: 3726-3733. PMID 2431041 |
0.456 |
|
1986 |
Bretscher PA. How significant are 'autoreactive' T cells? Immunology Today. 7: 301-302. DOI: 10.1016/0167-5699(86)90066-6 |
0.43 |
|
1984 |
Bretscher PA, Wilkins J, Diner UE. Hapten-Ficoll conjugates induce T-cell-dependent IgM anti-hapten responses and T cells mediating hapten-specific delayed-type hypersensitivity Cellular Immunology. 85: 396-405. PMID 6201291 DOI: 10.1016/0008-8749(84)90253-3 |
0.471 |
|
1984 |
Bretscher PA. In vitro induction of specific T cells able to help in the generation of delayed-type hypersensitivity by thymus-dependent and type-II 'thymus-independent' antigens Scandinavian Journal of Immunology. 20: 519-525. PMID 6083601 |
0.432 |
|
1983 |
Bretscher PA. Regulation of the class of immune response induced by antigen. I. Specific T cells switch the in vivo response from a cell-mediated to humoral mode Cellular Immunology. 81: 345-356. PMID 6227392 DOI: 10.1016/0008-8749(83)90242-3 |
0.468 |
|
1983 |
Bretscher PA. In vitro analysis of the cellular interactions between unprimed lymphocytes responsible for determining the class of response an antigen induces: Specific T cells switch a cell-mediated response to a humoral response Journal of Immunology. 131: 1103-1107. PMID 6193175 |
0.384 |
|
1982 |
Tucker MJ, Bretscher PA. T cells cooperating in the induction of delayed-type hypersensitivity act via the linked recognition of antigenic determinants Journal of Experimental Medicine. 155: 1037-1049. PMID 6174668 |
0.384 |
|
1981 |
Bretscher PA. Significance and mechanisms of cellular regulation of the immune response Federation Proceedings. 40: 1473-1478. PMID 6452291 |
0.409 |
|
1979 |
Bretscher PA. In vitro induction of delayed-type hypersensitivity European Journal of Immunology. 9: 311-316. PMID 89035 |
0.306 |
|
1977 |
Ramshaw IA, Bretscher PA, Parish CR. Regulation of the immune response. II. Repressor T cells in cyclophosphamide induced tolerant mice European Journal of Immunology. 7: 180-185. PMID 324776 |
0.383 |
|
1977 |
Ramshaw IA, McKenzie IFC, Bretscher PA, Parish CR. Discrimination of suppressor T cells of humoral and cell-mediated immunity by anti-Ly and anti-Ia sera Cellular Immunology. 31: 364-369. PMID 301441 DOI: 10.1016/0008-8749(77)90038-7 |
0.477 |
|
1977 |
Pilarski LM, Bretscher PA, Baum LL. Helper T cells are required for the polyclonal stimulation of cytotoxic T cells by concanavalin A Journal of Experimental Medicine. 145: 1237-1249. PMID 300781 |
0.473 |
|
1976 |
Ramshaw IA, Bretscher PA, Parish CR. Regulation of the immune response. I. Suppression of delayed type hypersensitivity by T cells from mice expressing humoral immunity European Journal of Immunology. 6: 674-679. PMID 1087845 |
0.445 |
|
1974 |
Bretscher PA. On the control between cell-mediated, IgM and IgG immunity Cellular Immunology. 13: 171-195. PMID 4451975 DOI: 10.1016/0008-8749(74)90237-8 |
0.303 |
|
1973 |
Bretscher P. Hypothesis: A model for generalised autoimmunity Cellular Immunology. 6: 1-11. PMID 4119340 DOI: 10.1016/0008-8749(73)90001-4 |
0.313 |
|
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