Year |
Citation |
Score |
2023 |
Dolgalev I, Zhou H, Murrell N, Le H, Sakellaropoulos T, Coudray N, Zhu K, Vasudevaraja V, Yeaton A, Goparaju C, Li Y, Sulaiman I, Tsay JJ, Meyn P, Mohamed H, ... ... Tsirigos A, et al. Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma. Nature Communications. 14: 6764. PMID 37938580 DOI: 10.1038/s41467-023-42327-x |
0.586 |
|
2023 |
Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, ... ... Tsirigos A, et al. Author Correction: Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment. Nature Communications. 14: 3912. PMID 37400453 DOI: 10.1038/s41467-023-39680-2 |
0.583 |
|
2023 |
Glytsou C, Chen X, Zacharioudakis E, Al-Santli W, Zhou H, Nadorp B, Lee S, Lasry A, Sun Z, Papaioannou D, Cammer M, Wang K, Zal T, Zal MA, Carter BZ, ... ... Tsirigos A, et al. Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer Discovery. PMID 37088914 DOI: 10.1158/2159-8290.CD-22-0601 |
0.506 |
|
2023 |
Davalos V, Lovell CD, Von Itter R, Dolgalev I, Agrawal P, Baptiste G, Kahler DJ, Sokolova E, Moran S, Piqué L, Vega-Saenz de Miera E, Fontanals-Cirera B, Karz A, Tsirigos A, Yun C, et al. An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma. Nature Communications. 14: 1867. PMID 37015919 DOI: 10.1038/s41467-023-36967-2 |
0.607 |
|
2023 |
Battistello E, Hixon KA, Comstock DE, Collings CK, Chen X, Rodriguez Hernaez J, Lee S, Cervantes KS, Hinkley MM, Ntatsoulis K, Cesarano A, Hockemeyer K, Haining WN, Witkowski MT, Qi J, ... Tsirigos A, et al. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Molecular Cell. PMID 36944333 DOI: 10.1016/j.molcel.2023.02.026 |
0.558 |
|
2023 |
Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, ... ... Tsirigos A, et al. Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment. Nature Communications. 14: 797. PMID 36781852 DOI: 10.1038/s41467-023-36296-4 |
0.634 |
|
2023 |
Lasry A, Nadorp B, Fornerod M, Nicolet D, Wu H, Walker CJ, Sun Z, Witkowski MT, Tikhonova AN, Guillamot-Ruano M, Cayanan G, Yeaton A, Robbins G, Obeng EA, Tsirigos A, et al. Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia. Nature Cancer. PMID 36658429 DOI: 10.1038/s43018-023-00518-x |
0.454 |
|
2023 |
Tan J, Shenker-Tauris N, Rodriguez-Hernaez J, Wang E, Sakellaropoulos T, Boccalatte F, Thandapani P, Skok J, Aifantis I, Fenyö D, Xia B, Tsirigos A. Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening. Nature Biotechnology. PMID 36624151 DOI: 10.1038/s41587-022-01612-8 |
0.528 |
|
2022 |
Maiti G, Monteiro de Barros MR, Hu N, Dolgalev I, Roshan M, Foster JW, Tsirigos A, Wahlin KJ, Chakravarti S. Single cell RNA-seq of human cornea organoids identifies cell fates of a developing immature cornea. Pnas Nexus. 1: pgac246. PMID 36712326 DOI: 10.1093/pnasnexus/pgac246 |
0.598 |
|
2022 |
Lasry A, Nadorp B, Fornerod M, Nicolet D, Wu H, Walker CJ, Sun Z, Witkowski MT, Tikhonova AN, Guillamot-Ruano M, Cayanan G, Yeaton A, Robbins G, Obeng EA, Tsirigos A, et al. An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia. Nature Cancer. PMID 36581735 DOI: 10.1038/s43018-022-00480-0 |
0.528 |
|
2022 |
Yeaton A, Cayanan G, Loghavi S, Dolgalev I, Leddin EM, Loo CE, Torabifard H, Nicolet D, Wang J, Corrigan K, Paraskevopoulou V, Starczynowski DT, Wang E, Abdel-Wahab O, Viny AD, ... ... Tsirigos A, et al. The impact of inflammation-induced tumor plasticity during myeloid transformation. Cancer Discovery. PMID 35924979 DOI: 10.1158/2159-8290.CD-21-1146 |
0.667 |
|
2022 |
Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner TP, Rabinovich-Nikitin I, Ouchida AT, Margulets V, Nordstrøm LU, Riley JS, Dolgalev I, Chen Y, Wittig AJH, Pekson R, Mathew C, ... ... Tsirigos A, et al. Modulating mitofusins to control mitochondrial function and signaling. Nature Communications. 13: 3775. PMID 35798717 DOI: 10.1038/s41467-022-31324-1 |
0.542 |
|
2022 |
Carcamo S, Nguyen CB, Grossi E, Filipescu D, Alpsoy A, Dhiman A, Sun D, Narang S, Imig J, Martin TC, Parsons R, Aifantis I, Tsirigos A, Aguirre-Ghiso JA, Dykhuizen EC, et al. Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma. Cell Reports. 39: 110637. PMID 35385731 DOI: 10.1016/j.celrep.2022.110637 |
0.559 |
|
2022 |
Moubarak RS, de Pablos-Aragoneses A, Ortiz-Barahona V, Gong Y, Gowen M, Dolgalev I, Shadaloey SAA, Argibay D, Karz A, Von Itter R, Vega-Sáenz de Miera EC, Sokolova E, Darvishian F, Tsirigos A, Osman I, et al. The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis. Science Advances. 8: eabi7127. PMID 35179962 DOI: 10.1126/sciadv.abi7127 |
0.618 |
|
2022 |
Thandapani P, Kloetgen A, Witkowski MT, Glytsou C, Lee AK, Wang E, Wang J, LeBoeuf SE, Avrampou K, Papagiannakopoulos T, Tsirigos A, Aifantis I. Valine tRNA levels and availability regulate complex I assembly in leukaemia. Nature. 601: 428-433. PMID 34937946 DOI: 10.1038/s41586-021-04244-1 |
0.543 |
|
2021 |
Kim RH, Nomikou S, Coudray N, Jour G, Dawood Z, Hong R, Esteva E, Sakellaropoulos T, Donnelly D, Moran U, Hatzimemos A, Weber JS, Razavian N, Aifantis I, Fenyo D, ... ... Tsirigos A, et al. Deep learning and pathomics analyses reveal cell nuclei as important features for mutation prediction of BRAF-mutated melanomas. The Journal of Investigative Dermatology. PMID 34757067 DOI: 10.1016/j.jid.2021.09.034 |
0.472 |
|
2021 |
Hu H, Khodadadi-Jamayran A, Dolgalev I, Cho H, Badri S, Chiriboga LA, Zeck B, Lopez De Rodas Gregorio M, Dowling CM, Labbe K, Deng J, Chen T, Zhang H, Zappile P, Chen Z, ... ... Tsirigos A, et al. Targeting the Atf7ip-Setdb1 complex augments antitumor immunity by boosting tumor immunogenicity. Cancer Immunology Research. PMID 34462284 DOI: 10.1158/2326-6066.CIR-21-0543 |
0.613 |
|
2021 |
Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng D, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, ... ... Tsirigos A, et al. ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. Nature Cancer. 2: 503-514. PMID 34142094 DOI: 10.1038/s43018-021-00208-6 |
0.538 |
|
2021 |
Wang E, Zhou H, Nadorp B, Cayanan G, Chen X, Yeaton AH, Nomikou S, Witkowski MT, Narang S, Kloetgen A, Thandapani P, Ravn-Boess N, Tsirigos A, Aifantis I. Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation. Cell Stem Cell. PMID 33450187 DOI: 10.1016/j.stem.2020.12.005 |
0.576 |
|
2020 |
Cui X, Ma C, Vasudevaraja V, Serrano J, Tong J, Peng Y, Delorenzo M, Shen G, Frenster J, Morales RT, Qian W, Tsirigos A, Chi AS, Jain R, Kurz SC, et al. Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapy. Elife. 9. PMID 32909947 DOI: 10.7554/Elife.52253 |
0.3 |
|
2020 |
Moro L, Simoneschi D, Kurz E, Arbini AA, Jang S, Guaragnella N, Giannattasio S, Wang W, Chen YA, Pires G, Dang A, Hernandez E, Kapur P, Mishra A, Tsirigos A, et al. Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. Nature Cell Biology. PMID 32839549 DOI: 10.1038/S41556-020-0560-6 |
0.335 |
|
2020 |
Witkowski MT, Dolgalev I, Evensen NA, Ma C, Chambers T, Roberts KG, Sreeram S, Dai Y, Tikhonova AN, Lasry A, Qu C, Pei D, Cheng C, Robbins GA, Pierro J, ... ... Tsirigos A, et al. Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia. Cancer Cell. PMID 32470390 DOI: 10.1016/J.Ccell.2020.04.015 |
0.686 |
|
2020 |
Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Guttierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, ... ... Tsirigos A, et al. Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia. Cancer Discovery. PMID 32444465 DOI: 10.1158/2159-8290.Cd-19-1436 |
0.6 |
|
2020 |
Nishana M, Ha C, Rodriguez-Hernaez J, Ranjbaran A, Chio E, Nora EP, Badri SB, Kloetgen A, Bruneau BG, Tsirigos A, Skok JA. Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation. Genome Biology. 21: 108. PMID 32393311 DOI: 10.1186/S13059-020-02024-0 |
0.319 |
|
2020 |
Pierro J, Saliba J, Narang S, Sethia G, Saint Fleur-Lominy S, Chowdhury A, Qualls A, Fay H, Kilberg HL, Moriyama T, Fuller TJ, Teachey DT, Schmiegelow K, Yang JJ, Loh ML, ... ... Tsirigos A, et al. The NSD2 p.E1099K Mutation is Enriched at Relapse and Confers Drug Resistance in a Cell Context Dependent Manner in Pediatric Acute Lymphoblastic Leukemia. Molecular Cancer Research : McR. PMID 32332049 DOI: 10.1158/1541-7786.Mcr-20-0092 |
0.361 |
|
2020 |
Kloetgen A, Thandapani P, Ntziachristos P, Ghebrechristos Y, Nomikou S, Lazaris C, Chen X, Hu H, Bakogianni S, Wang J, Fu Y, Boccalatte F, Zhong H, Paietta E, Trimarchi T, ... ... Tsirigos A, et al. Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia. Nature Genetics. PMID 32203470 DOI: 10.1038/S41588-020-0602-9 |
0.586 |
|
2020 |
Lazaris C, Aifantis I, Tsirigos A. On Epigenetic Plasticity and Genome Topology. Trends in Cancer. 6: 177-180. PMID 32101721 DOI: 10.1016/J.Trecan.2020.01.006 |
0.555 |
|
2020 |
Hanniford D, Ulloa-Morales A, Karz A, Berzoti-Coelho MG, Moubarak RS, Sánchez-Sendra B, Kloetgen A, Davalos V, Imig J, Wu P, Vasudevaraja V, Argibay D, Lilja K, Tabaglio T, Monteagudo C, ... ... Tsirigos A, et al. Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. Cancer Cell. 37: 55-70.e15. PMID 31935372 DOI: 10.1016/J.Ccell.2019.12.007 |
0.565 |
|
2020 |
Hatzioannou A, Banos A, Sakelaropoulos T, Fedonidis C, Vidali MS, Köhne M, Händler K, Boon L, Henriques A, Koliaraki V, Georgiadis P, Zoidakis J, Termentzi A, Beyer M, Chavakis T, ... ... Tsirigos A, et al. An intrinsic role of IL-33 in T cell-mediated tumor immunoevasion. Nature Immunology. 21: 75-85. PMID 31844326 DOI: 10.1038/S41590-019-0555-2 |
0.335 |
|
2020 |
Adorno Febles VR, Adeegbe D, Ahsan A, Wu J, Khodadad-Jamayran A, Lepor H, Wysock J, Taneja S, Huang WC, Balar AV, Melamed J, Deng F, Ren Q, Tsirigos A, Kufe DW, et al. Immunosuppressive milieu of high-risk localized prostate cancer. Journal of Clinical Oncology. 38: 344-344. DOI: 10.1200/Jco.2020.38.6_Suppl.344 |
0.335 |
|
2020 |
Pierro J, Saliba J, Narang S, Sethia G, Fleur-Lominy SS, Chowdhury A, Moriyama T, Schmiegelow K, Yang JJ, Loh ML, Brown PA, Zhang J, Ma X, Tsirigos A, Evensen NA, et al. Abstract 5399: The NSD2 p.E1099K mutation is enriched at relapse and confers drug resistance in a cell context dependent manner in pediatric acute lymphoblastic leukemia Cancer Research. 80: 5399-5399. DOI: 10.1158/1538-7445.Am2020-5399 |
0.38 |
|
2020 |
Doudican N, Frazzette N, Khodadadi-Jamayran A, Tsirigos A, Carucci J. 137 Decreased cytotoxic T cells, decreased cytotoxic/regulatory T-cell ratio, and decreased TCR clonality are associated with increased numbers of primary cutaneous squamous cell carcinomas in solid organ transplant recipients Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.140 |
0.319 |
|
2019 |
Halaby MJ, Hezaveh K, Lamorte S, Ciudad MT, Kloetgen A, MacLeod BL, Guo M, Chakravarthy A, Medina TDS, Ugel S, Tsirigos A, Bronte V, Munn DH, Pugh TJ, De Carvalho DD, et al. GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment. Science Immunology. 4. PMID 31836669 DOI: 10.1126/Sciimmunol.Aax8189 |
0.404 |
|
2019 |
Sakellaropoulos T, Vougas K, Narang S, Koinis F, Kotsinas A, Polyzos A, Moss TJ, Piha-Paul S, Zhou H, Kardala E, Damianidou E, Alexopoulos LG, Aifantis I, Townsend PA, Panayiotidis MI, ... ... Tsirigos A, et al. A Deep Learning Framework for Predicting Response to Therapy in Cancer. Cell Reports. 29: 3367-3373.e4. PMID 31825821 DOI: 10.1016/J.Celrep.2019.11.017 |
0.521 |
|
2019 |
Li F, Huang Q, Luster TA, Hu H, Zhang H, Ng WL, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling CM, Bagdatlioglu E, ... ... Tsirigos A, et al. In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma. Cancer Discovery. PMID 31744829 DOI: 10.1158/2159-8290.Cd-19-0780 |
0.367 |
|
2019 |
Bledea R, Vasudevaraja V, Patel S, Stafford J, Serrano J, Esposito G, Tredwin LM, Goodman N, Kloetgen A, Golfinos JG, Zagzag D, Weigelt B, Iafrate AJ, Sulman EP, Chi AS, ... ... Tsirigos A, et al. Functional and topographic effects on DNA methylation in IDH1/2 mutant cancers. Scientific Reports. 9: 16830. PMID 31727977 DOI: 10.1038/S41598-019-53262-7 |
0.334 |
|
2019 |
Yusufova N, Teater MR, Soshnev A, Kloetgen A, Osunsade A, Conway J, Doane A, Skoultchi A, Tsirigos A, David Y, Allis CD, Cesarman E, Melnick A. Histone 1 Mutations Drive Lymphomagenesis By Inducing Primitive Stem Cell Functions and Epigenetic Instructions through Profound 3D Re-Organization of the B-Cell Genome. Blood. 134: 23. PMID 31723979 DOI: 10.1182/Blood-2019-127774 |
0.357 |
|
2019 |
Lhoumaud P, Badri S, Rodriguez-Hernaez J, Sakellaropoulos T, Sethia G, Kloetgen A, Cornwell M, Bhattacharyya S, Ay F, Bonneau R, Tsirigos A, Skok JA. NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains. Nature Communications. 10: 4843. PMID 31649247 DOI: 10.1038/S41467-019-12811-4 |
0.338 |
|
2019 |
Di Giammartino DC, Kloetgen A, Polyzos A, Liu Y, Kim D, Murphy D, Abuhashem A, Cavaliere P, Aronson B, Shah V, Dephoure N, Stadtfeld M, Tsirigos A, Apostolou E. KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks. Nature Cell Biology. PMID 31548608 DOI: 10.1038/S41556-019-0390-6 |
0.398 |
|
2019 |
Saldaña-Meyer R, Rodriguez-Hernaez J, Escobar T, Nishana M, Jácome-López K, Nora EP, Bruneau BG, Tsirigos A, Furlan-Magaril M, Skok J, Reinberg D. RNA Interactions Are Essential for CTCF-Mediated Genome Organization. Molecular Cell. PMID 31522988 DOI: 10.1016/J.Molcel.2019.08.015 |
0.321 |
|
2019 |
Kloetgen A, Thandapani P, Tsirigos A, Aifantis I. 3D Chromosomal Landscapes in Hematopoiesis and Immunity. Trends in Immunology. PMID 31422902 DOI: 10.1016/J.It.2019.07.003 |
0.57 |
|
2019 |
Guillamot M, Ouazia D, Dolgalev I, Yeung ST, Kourtis N, Dai Y, Corrigan K, Zea-Redondo L, Saraf A, Florens L, Washburn MP, Tikhonova AN, Malumbres M, Gong Y, Tsirigos A, et al. The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation. Nature Immunology. PMID 31406379 DOI: 10.1038/S41590-019-0454-6 |
0.691 |
|
2019 |
Vougas K, Sakelaropoulos T, Kotsinas A, Foukas GP, Ntargaras A, Koinis F, Polyzos A, Myrianthopoulos V, Zhou H, Narang S, Georgoulias V, Alexopoulos L, Aifantis I, Townsend PA, Sfikakis P, ... ... Tsirigos A, et al. Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining. Pharmacology & Therapeutics. 107395. PMID 31374225 DOI: 10.1016/J.Pharmthera.2019.107395 |
0.513 |
|
2019 |
Yu M, Scherwitzl I, Opp S, Tsirigos A, Meruelo D. Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody. Journal For Immunotherapy of Cancer. 7: 185. PMID 31307539 DOI: 10.1186/S40425-019-0664-3 |
0.316 |
|
2019 |
Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, ... ... Tsirigos A, et al. Author Correction: The bone marrow microenvironment at single-cell resolution. Nature. PMID 31296938 DOI: 10.1038/S41586-019-1394-X |
0.667 |
|
2019 |
Lignitto L, LeBoeuf SE, Homer H, Jiang S, Askenazi M, Karakousi TR, Pass HI, Bhutkar AJ, Tsirigos A, Ueberheide B, Sayin VI, Papagiannakopoulos T, Pagano M. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Cell. PMID 31257023 DOI: 10.1016/J.Cell.2019.06.003 |
0.301 |
|
2019 |
Chen X, Glytsou C, Zhou H, Narang S, Reyna DE, Lopez A, Sakellaropoulos T, Gong Y, Kloetgen A, Yap YS, Wang E, Gavathiotis E, Tsirigos A, Tibes R, Aifantis I. Targeting mitochondrial structure sensitizes acute myeloid leukemia to Venetoclax treatment. Cancer Discovery. PMID 31048321 DOI: 10.1158/2159-8290.Cd-19-0117 |
0.547 |
|
2019 |
Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, ... ... Tsirigos A, et al. The bone marrow microenvironment at single-cell resolution. Nature. PMID 30971824 DOI: 10.1038/S41586-019-1104-8 |
0.701 |
|
2019 |
Tetz G, Vikina D, Brown S, Zappile P, Dolgalev I, Tsirigos A, Heguy A, Tetz V. Draft Genome Sequence of Streptococcus halitosis sp. nov., Isolated from the Dorsal Surface of the Tongue of a Patient with Halitosis. Microbiology Resource Announcements. 8. PMID 30701262 DOI: 10.1128/MRA.01704-18 |
0.532 |
|
2019 |
Deng J, Thennavan A, Pan Y, Dolgalev I, Chen T, Silver H, Harris M, Pyon V, Li F, Lee C, Tsirigos A, Rothenberg E, Perou CM, Wong K. Abstract 3223: Overcome LKB1 mutated cancer resistance to anti-PD1 treatment Cancer Research. 79: 3223-3223. DOI: 10.1158/1538-7445.Am2019-3223 |
0.625 |
|
2019 |
Doudican N, Santana A, Felsen D, Khodadadi-Jamayran A, Tsirigos A, Carucci J. 135 Defining the T cell landscape and neoantigens via T-cell receptor sequencing and gene expression profiling in cutaneous squamous cell carcinoma Journal of Investigative Dermatology. 139: S24. DOI: 10.1016/J.Jid.2019.03.211 |
0.337 |
|
2019 |
Witkowski M, Dolgalev I, Evensen N, Roberts K, Sreeram S, Dai Y, Tikhonova A, Loomis C, Mullighan C, Tsirigos A, Carroll W, Aifantis I. 2029 - THE RELAPSED B-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA IMMUNE MICROENVIRONMENT Experimental Hematology. 76: S49. DOI: 10.1016/J.Exphem.2019.06.301 |
0.704 |
|
2018 |
Xiong X, Schober M, Tassone E, Khodadadi-Jamayran A, Sastre-Perona A, Zhou H, Tsirigos A, Shen S, Chang M, Melamed J, Ossowski L, Wilson EL. KLF4, A Gene Regulating Prostate Stem Cell Homeostasis, Is a Barrier to Malignant Progression and Predictor of Good Prognosis in Prostate Cancer. Cell Reports. 25: 3006-3020.e7. PMID 30540935 DOI: 10.1016/J.Celrep.2018.11.065 |
0.359 |
|
2018 |
Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, et al. Cell surface Notch ligand DLL3 is a therapeutic target in isocitrate dehydrogenase mutant glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30397180 DOI: 10.1158/1078-0432.Ccr-18-2312 |
0.305 |
|
2018 |
Adeegbe DO, Liu S, Hattersley M, Bowden M, Zhou CW, Li S, Vlahos R, Grondine M, Dolgalev I, Ivanova E, Quinn MM, Gao P, Hammerman PS, Bradner JE, Diehl JA, ... ... Tsirigos A, et al. BET bromodomain inhibition cooperates with PD-1 blockade to facilitate antitumor response in Kras-mutant non-small cell lung cancer. Cancer Immunology Research. PMID 30087114 DOI: 10.1158/2326-6066.Cir-18-0077 |
0.63 |
|
2018 |
Kourtis N, Lazaris C, Hockemeyer K, Balandrán JC, Jimenez AR, Mullenders J, Gong Y, Trimarchi T, Bhatt K, Hu H, Shrestha L, Ambesi-Impiombato A, Kelliher M, Paietta E, Chiosis G, ... ... Tsirigos A, et al. Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia. Nature Medicine. PMID 30038221 DOI: 10.1038/S41591-018-0105-8 |
0.576 |
|
2018 |
Smith-Raska MR, Arenzana TL, D'Cruz LM, Khodadadi-Jamayran A, Tsirigos A, Goldrath AW, Reizis B. The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation. Frontiers in Immunology. 9: 1482. PMID 30022979 DOI: 10.3389/Fimmu.2018.01482 |
0.384 |
|
2018 |
Shekhar A, Lin X, Lin B, Liu FY, Zhang J, Khodadadi-Jamayran A, Tsirigos A, Bu L, Fishman GI, Park DS. ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes. Scientific Reports. 8: 9944. PMID 29967479 DOI: 10.1038/S41598-018-28239-7 |
0.309 |
|
2018 |
Kirkling ME, Cytlak U, Lau CM, Lewis KL, Resteu A, Khodadadi-Jamayran A, Siebel CW, Salmon H, Merad M, Tsirigos A, Collin M, Bigley V, Reizis B. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Reports. 23: 3658-3672.e6. PMID 29925006 DOI: 10.1016/J.Celrep.2018.05.068 |
0.358 |
|
2018 |
Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, ... ... Tsirigos A, et al. Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nature Immunology. PMID 29760532 DOI: 10.1038/S41590-018-0107-1 |
0.336 |
|
2018 |
Gong Y, Lazaris C, Sakellaropoulos T, Lozano A, Kambadur P, Ntziachristos P, Aifantis I, Tsirigos A. Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries. Nature Communications. 9: 542. PMID 29416042 DOI: 10.1038/S41467-018-03017-1 |
0.53 |
|
2018 |
Sen R, Dolgalev I, Bayin NS, Heguy A, Tsirigos A, Placantonakis DG. Single-Cell RNA Sequencing of Glioblastoma Cells. Methods in Molecular Biology (Clifton, N.J.). 1741: 151-170. PMID 29392698 DOI: 10.1007/978-1-4939-7659-1_12 |
0.598 |
|
2018 |
Nancy P, Siewiera J, Rizzuto G, Tagliani E, Osokine I, Manandhar P, Dolgalev I, Clementi C, Tsirigos A, Erlebacher A. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. The Journal of Clinical Investigation. 128: 233-247. PMID 29202469 DOI: 10.1172/Jci95937 |
0.604 |
|
2018 |
Kloetgen A, Serrano J, Patel S, Bowman C, Shen G, Zagzag D, Karajannis MA, Golfinos JG, Placantonakis D, Tsirigos A, Chi AS, Snuderl M. Abstract 3658: DNA methylation of circulating tumor educated leukocytes predicts IDH1/2 mutation status in adult patients with diffuse gliomas Cancer Research. 78: 3658-3658. DOI: 10.1158/1538-7445.Am2018-3658 |
0.32 |
|
2018 |
Thandapani P, Kloetgen A, Lazaris C, Chen X, Ntziachristos P, Tsirigos A, Aifantis I. Abstract 2998: Dynamic 3d chromosomal landscapes in acute leukemia Cancer Research. 78: 2998-2998. DOI: 10.1158/1538-7445.Am2018-2998 |
0.607 |
|
2017 |
Brown JA, Yonekubo Y, Hanson N, Sastre-Perona A, Basin A, Rytlewski JA, Dolgalev I, Meehan S, Tsirigos A, Beronja S, Schober M. TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. Cell Stem Cell. 21: 650-664.e8. PMID 29100014 DOI: 10.1016/J.Stem.2017.10.001 |
0.637 |
|
2017 |
Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, ... ... Tsirigos A, et al. Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2. Cell Reports. 21: 1267-1280. PMID 29091765 DOI: 10.1016/J.Celrep.2017.10.009 |
0.367 |
|
2017 |
Tetz G, Vecherkovskaya M, Zappile P, Dolgalev I, Tsirigos A, Heguy A, Tetz V. Complete Genome Sequence of Kluyvera intestini sp. nov., Isolated from the Stomach of a Patient with Gastric Cancer. Genome Announcements. 5. PMID 29074664 DOI: 10.1128/Genomea.01184-17 |
0.574 |
|
2017 |
Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, ... Tsirigos A, et al. Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. Oncotarget. 8: 64932-64953. PMID 29029402 DOI: 10.18632/Oncotarget.18117 |
0.627 |
|
2017 |
Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, Martín MT, Guillamot M, ... ... Tsirigos A, et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. Cell. PMID 28823558 DOI: 10.1016/J.Cell.2017.07.032 |
0.715 |
|
2017 |
Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, ... Tsirigos A, et al. Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. Oncotarget. PMID 28586758 DOI: 10.18632/oncotarget.18117 |
0.592 |
|
2017 |
Gong Y, Huang HT, Liang Y, Trimarchi T, Aifantis I, Tsirigos A. lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets. Bmc Genomics. 18: 434. PMID 28583068 DOI: 10.1186/S12864-017-3817-0 |
0.532 |
|
2017 |
Rigoutsos I, Lee SK, Nam SY, Anfossi S, Pasculli B, Pichler M, Jing Y, Rodriguez-Aguayo C, Telonis AG, Rossi S, Ivan C, Catela Ivkovic T, Fabris L, Clark PM, Ling H, ... ... Tsirigos A, et al. N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration. Genome Biology. 18: 98. PMID 28535802 DOI: 10.1186/S13059-017-1224-0 |
0.308 |
|
2017 |
Strikoudis A, Lazaris C, Ntziachristos P, Tsirigos A, Aifantis I. Opposing functions of H2BK120 ubiquitylation and H3K79 methylation in the regulation of pluripotency by the Paf1 complex. Cell Cycle (Georgetown, Tex.). 0. PMID 28272987 DOI: 10.1080/15384101.2017.1295194 |
0.596 |
|
2017 |
Lazaris C, Kelly S, Ntziachristos P, Aifantis I, Tsirigos A. HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking. Bmc Genomics. 18: 22. PMID 28056762 DOI: 10.1186/S12864-016-3387-6 |
0.505 |
|
2017 |
Fleur-Lominy SS, Bhatla T, Kelly S, Vasudevaraja V, Tsirigos A, Carroll WL. Genomic and Epigenetic Effects of DNA Methyltransferase Inhibition in Acute Lymphoblastic Leukemia Blood. 130: 2479-2479. DOI: 10.1182/Blood.V130.Suppl_1.2479.2479 |
0.356 |
|
2017 |
Modrek A, Golub D, Khan T, Prado J, Bowman C, Deng J, Zhang G, Rocha P, Raviram R, Lazaris H, Kader M, Dhaliwal J, Chi A, Golfinos J, Tsirigos A, et al. LGG-11. LOW-GRADE ASTROCYTOMA CORE MUTATIONS IN IDH1, P53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF HUMAN NEURAL STEM CELLS VIA EPIGENETIC REPRESSION OF SOX2 Neuro-Oncology. 19: iv35-iv35. DOI: 10.1093/Neuonc/Nox083.144 |
0.335 |
|
2016 |
Gutiérrez GD, Bender AS, Cirulli V, Mastracci TL, Kelly SM, Tsirigos A, Kaestner KH, Sussel L. Pancreatic β cell identity requires continual repression of non-β cell programs. The Journal of Clinical Investigation. PMID 27941248 DOI: 10.1172/Jci88017 |
0.318 |
|
2016 |
Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I. Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nature Cell Biology. PMID 27749823 DOI: 10.1038/Ncb3424 |
0.715 |
|
2016 |
Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, Sánchez-Díaz M, Wang K, Kayembe C, Zhang N, Amoasii L, ... ... Tsirigos A, et al. MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell. PMID 27570068 DOI: 10.1016/J.Stem.2016.08.004 |
0.595 |
|
2016 |
Kannan KS, Tsirigos A, Serrano J, Forrester LA, Faustin A, Thomas C, Capper D, Hovestadt V, Pfister SM, Jones DTW, Sill M, Schrimpf D, Deimling Av, Heguy A, Gardner SL, et al. Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management Clinical Cancer Research. 22: 11-11. DOI: 10.1158/1557-3265.Pmsclingen15-11 |
0.309 |
|
2016 |
Modrek A, Golub D, Khan T, Zhang G, Kader M, Bowman C, Prado J, Bayin NS, Frenster J, Lhakhang T, Heguy A, Dankert J, Tsirigos A, Snuderl M, Neubert T, et al. STMC-21. ASTROCYTOMA MUTATIONS IDH1, p53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF NEURAL STEM CELLS VIA Sox2 Neuro-Oncology. 18: vi187-vi187. DOI: 10.1093/Neuonc/Now212.784 |
0.307 |
|
2016 |
Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Schrewe H, Tsirigos A, Zon L, Aifantis I. Med12 is an essential regulator of enhancer dynamics in hematopoietic stem cells Experimental Hematology. 44: S57. DOI: 10.1016/J.Exphem.2016.06.086 |
0.565 |
|
2015 |
Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, et al. Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms. The Journal of Experimental Medicine. PMID 26438359 DOI: 10.1084/Jem.20151323 |
0.619 |
|
2015 |
Pitt LA, Tikhonova AN, Hu H, Trimarchi T, King B, Gong Y, Sanchez-Martin M, Tsirigos A, Littman DR, Ferrando AA, Morrison SJ, Fooksman DR, Aifantis I, Schwab SR. CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance. Cancer Cell. 27: 755-68. PMID 26058075 DOI: 10.1016/J.Ccell.2015.05.002 |
0.522 |
|
2015 |
Kourtis N, Moubarak RS, Aranda-Orgilles B, Lui K, Aydin IT, Trimarchi T, Darvishian F, Salvaggio C, Zhong J, Bhatt K, Chen EI, Celebi JT, Lazaris C, Tsirigos A, Osman I, et al. FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification. Nature Cell Biology. 17: 322-32. PMID 25720964 DOI: 10.1038/Ncb3121 |
0.581 |
|
2015 |
Pitt LA, Tikhonova AN, Trimarchi T, King B, Hu H, Gong Y, Tsirigos A, Sanchez-Martin M, Littman DR, Ferrando A, Morrison SJ, Fooksman DR, Aifantis I, Schwab S. Abstract A06: The chemokine receptor CXCR4 is essential for the maintenance of T cell acute lymphoblastic leukemia. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A06 |
0.536 |
|
2014 |
Vidal SE, Amlani B, Chen T, Tsirigos A, Stadtfeld M. Combinatorial modulation of signaling pathways reveals cell-type-specific requirements for highly efficient and synchronous iPSC reprogramming. Stem Cell Reports. 3: 574-84. PMID 25358786 DOI: 10.1016/J.Stemcr.2014.08.003 |
0.364 |
|
2014 |
Di Micco R, Fontanals-Cirera B, Low V, Ntziachristos P, Yuen SK, Lovell CD, Dolgalev I, Yonekubo Y, Zhang G, Rusinova E, Gerona-Navarro G, Cañamero M, Ohlmeyer M, Aifantis I, Zhou MM, ... Tsirigos A, et al. Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes. Cell Reports. 9: 234-47. PMID 25263550 DOI: 10.1016/J.Celrep.2014.08.055 |
0.716 |
|
2014 |
Ntziachristos P, Tsirigos A, Welstead GG, Trimarchi T, Bakogianni S, Xu L, Loizou E, Holmfeldt L, Strikoudis A, King B, Mullenders J, Becksfort J, Nedjic J, Paietta E, Tallman MS, et al. Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia. Nature. 514: 513-7. PMID 25132549 DOI: 10.1038/Nature13605 |
0.598 |
|
2014 |
Trimarchi T, Bilal E, Ntziachristos P, Fabbri G, Dalla-Favera R, Tsirigos A, Aifantis I. Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia. Cell. 158: 593-606. PMID 25083870 DOI: 10.1016/J.Cell.2014.05.049 |
0.59 |
|
2014 |
Siegle JM, Basin A, Sastre-Perona A, Yonekubo Y, Brown J, Sennett R, Rendl M, Tsirigos A, Carucci JA, Schober M. SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma. Nature Communications. 5: 4511. PMID 25077433 DOI: 10.1038/Ncomms5511 |
0.375 |
|
2014 |
Lisanti MP, Tsirigos A, Pavlides S, Reeves KJ, Peiris-Pagès M, Chadwick AL, Sanchez-Alvarez R, Lamb R, Howell A, Martinez-Outschoorn UE, Sotgia F. JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention. Cell Cycle (Georgetown, Tex.). 13: 580-99. PMID 24434780 DOI: 10.4161/Cc.27379 |
0.335 |
|
2014 |
Ntziachristos P, Tsirigos A, Welstead G, Trimarchi T, Holmfeldt L, Satoh T, Paietta EM, Tallman MS, Rowe JM, Tonon G, Becksfort J, Kruidenier L, Prinjha RK, Van Vlierberghe P, Jaenisch R, et al. An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia Blood. 124: 56-56. DOI: 10.1182/Blood.V124.21.56.56 |
0.625 |
|
2013 |
Ntziachristos P, Tsirigos A, Trimarchi T, Loizou E, Luyao X, Vlierberghe PV, King B, Welstead G, Mullighan C, Jaenisch R, Ferrando A, Aifantis I. Abstract A07: Characterizing the specific oncogenic and tumor suppressor roles of H3K27me3 epigenetic modulators in T cell leukemia Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A07 |
0.588 |
|
2012 |
Sotgia F, Whitaker-Menezes D, Martinez-Outschoorn UE, Salem AF, Tsirigos A, Lamb R, Sneddon S, Hulit J, Howell A, Lisanti MP. Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. Cell Cycle (Georgetown, Tex.). 11: 4390-401. PMID 23172368 DOI: 10.4161/Cc.22777 |
0.333 |
|
2012 |
Bonuccelli G, Castello-Cros R, Capozza F, Martinez-Outschoorn UE, Lin Z, Tsirigos A, Xuanmao J, Whitaker-Menezes D, Howell A, Lisanti MP, Sotgia F. The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis. Cell Cycle (Georgetown, Tex.). 11: 3972-82. PMID 23047602 DOI: 10.4161/Cc.22227 |
0.395 |
|
2012 |
Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle (Georgetown, Tex.). 11: 2285-302. PMID 22684298 DOI: 10.4161/Cc.20718 |
0.365 |
|
2012 |
Ntziachristos P, Tsirigos A, Van Vlierberghe P, Nedjic J, Trimarchi T, Flaherty MS, Ferres-Marco D, da Ros V, Tang Z, Siegle J, Asp P, Hadler M, Rigo I, De Keersmaecker K, Patel J, et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nature Medicine. 18: 298-301. PMID 22237151 DOI: 10.1038/Nm.2651 |
0.606 |
|
2012 |
Ertel A, Tsirigos A, Whitaker-Menezes D, Birbe RC, Pavlides S, Martinez-Outschoorn UE, Pestell RG, Howell A, Sotgia F, Lisanti MP. Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 11: 253-63. PMID 22234241 DOI: 10.4161/Cc.11.2.19006 |
0.307 |
|
2011 |
Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. Cell Cycle (Georgetown, Tex.). 10: 4047-64. PMID 22134189 DOI: 10.4161/Cc.10.23.18151 |
0.361 |
|
2011 |
Witkiewicz AK, Kline J, Queenan M, Brody JR, Tsirigos A, Bilal E, Pavlides S, Ertel A, Sotgia F, Lisanti MP. Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers. Cell Cycle (Georgetown, Tex.). 10: 1794-809. PMID 21521946 DOI: 10.4161/Cc.10.11.15675 |
0.389 |
|
2011 |
Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle (Georgetown, Tex.). 10: 1271-86. PMID 21512313 DOI: 10.4161/Cc.10.8.15330 |
0.395 |
|
2011 |
Witkiewicz AK, Kline J, Queenan M, Brody J, Sotgia F, Tsirigos A, Lisanti MP. Abstract 1510: Transcriptional profiling of a lethal breast cancer tumor microenvironment Cancer Research. 71: 1510-1510. DOI: 10.1158/1538-7445.Am2011-1510 |
0.393 |
|
2010 |
Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, Tsirigos A, Migneco G, Witkiewicz A, Balliet R, Mercier I, Wang C, Flomenberg N, Howell A, Lin Z, et al. The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox. Cell Cycle (Georgetown, Tex.). 9: 4297-306. PMID 21051947 DOI: 10.4161/Cc.9.21.13817 |
0.358 |
|
2010 |
Pavlides S, Tsirigos A, Migneco G, Whitaker-Menezes D, Chiavarina B, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. Cell Cycle (Georgetown, Tex.). 9: 3485-505. PMID 20861672 DOI: 10.4161/Cc.9.17.12721 |
0.324 |
|
2010 |
Lisanti MP, Martinez-Outschoorn UE, Chiavarina B, Pavlides S, Whitaker-Menezes D, Tsirigos A, Witkiewicz A, Lin Z, Balliet R, Howell A, Sotgia F. Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment. Cancer Biology & Therapy. 10: 537-42. PMID 20861671 DOI: 10.4161/Cbt.10.6.13370 |
0.375 |
|
2010 |
Bonuccelli G, Tsirigos A, Whitaker-Menezes D, Pavlides S, Pestell RG, Chiavarina B, Frank PG, Flomenberg N, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 9: 3506-14. PMID 20818174 DOI: 10.4161/Cc.9.17.12731 |
0.342 |
|
2010 |
Migneco G, Whitaker-Menezes D, Chiavarina B, Castello-Cros R, Pavlides S, Pestell RG, Fatatis A, Flomenberg N, Tsirigos A, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling. Cell Cycle (Georgetown, Tex.). 9: 2412-22. PMID 20562527 DOI: 10.4161/Cc.9.12.11989 |
0.347 |
|
2010 |
Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation. Cell Cycle (Georgetown, Tex.). 9: 2201-19. PMID 20519932 DOI: 10.4161/Cc.9.11.11848 |
0.389 |
|
2010 |
Laurent L, Wong E, Li G, Huynh T, Tsirigos A, Ong CT, Low HM, Kin Sung KW, Rigoutsos I, Loring J, Wei CL. Dynamic changes in the human methylome during differentiation. Genome Research. 20: 320-31. PMID 20133333 DOI: 10.1101/Gr.101907.109 |
0.362 |
|
2006 |
Rigoutsos I, Huynh T, Miranda K, Tsirigos A, McHardy A, Platt D. Short blocks from the noncoding parts of the human genome have instances within nearly all known genes and relate to biological processes. Proceedings of the National Academy of Sciences of the United States of America. 103: 6605-10. PMID 16636294 DOI: 10.1073/Pnas.0601688103 |
0.328 |
|
Show low-probability matches. |