Aristotelis Tsirigos, Ph.D. - Publications

Affiliations: 
2006 New York University, New York, NY, United States 
Area:
Computer Science, Artificial Intelligence

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dolgalev I, Zhou H, Murrell N, Le H, Sakellaropoulos T, Coudray N, Zhu K, Vasudevaraja V, Yeaton A, Goparaju C, Li Y, Sulaiman I, Tsay JJ, Meyn P, Mohamed H, ... ... Tsirigos A, et al. Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma. Nature Communications. 14: 6764. PMID 37938580 DOI: 10.1038/s41467-023-42327-x  0.586
2023 Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, ... ... Tsirigos A, et al. Author Correction: Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment. Nature Communications. 14: 3912. PMID 37400453 DOI: 10.1038/s41467-023-39680-2  0.583
2023 Glytsou C, Chen X, Zacharioudakis E, Al-Santli W, Zhou H, Nadorp B, Lee S, Lasry A, Sun Z, Papaioannou D, Cammer M, Wang K, Zal T, Zal MA, Carter BZ, ... ... Tsirigos A, et al. Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer Discovery. PMID 37088914 DOI: 10.1158/2159-8290.CD-22-0601  0.506
2023 Davalos V, Lovell CD, Von Itter R, Dolgalev I, Agrawal P, Baptiste G, Kahler DJ, Sokolova E, Moran S, Piqué L, Vega-Saenz de Miera E, Fontanals-Cirera B, Karz A, Tsirigos A, Yun C, et al. An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma. Nature Communications. 14: 1867. PMID 37015919 DOI: 10.1038/s41467-023-36967-2  0.607
2023 Battistello E, Hixon KA, Comstock DE, Collings CK, Chen X, Rodriguez Hernaez J, Lee S, Cervantes KS, Hinkley MM, Ntatsoulis K, Cesarano A, Hockemeyer K, Haining WN, Witkowski MT, Qi J, ... Tsirigos A, et al. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Molecular Cell. PMID 36944333 DOI: 10.1016/j.molcel.2023.02.026  0.558
2023 Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, ... ... Tsirigos A, et al. Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment. Nature Communications. 14: 797. PMID 36781852 DOI: 10.1038/s41467-023-36296-4  0.634
2023 Lasry A, Nadorp B, Fornerod M, Nicolet D, Wu H, Walker CJ, Sun Z, Witkowski MT, Tikhonova AN, Guillamot-Ruano M, Cayanan G, Yeaton A, Robbins G, Obeng EA, Tsirigos A, et al. Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia. Nature Cancer. PMID 36658429 DOI: 10.1038/s43018-023-00518-x  0.454
2023 Tan J, Shenker-Tauris N, Rodriguez-Hernaez J, Wang E, Sakellaropoulos T, Boccalatte F, Thandapani P, Skok J, Aifantis I, Fenyö D, Xia B, Tsirigos A. Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening. Nature Biotechnology. PMID 36624151 DOI: 10.1038/s41587-022-01612-8  0.528
2022 Maiti G, Monteiro de Barros MR, Hu N, Dolgalev I, Roshan M, Foster JW, Tsirigos A, Wahlin KJ, Chakravarti S. Single cell RNA-seq of human cornea organoids identifies cell fates of a developing immature cornea. Pnas Nexus. 1: pgac246. PMID 36712326 DOI: 10.1093/pnasnexus/pgac246  0.598
2022 Lasry A, Nadorp B, Fornerod M, Nicolet D, Wu H, Walker CJ, Sun Z, Witkowski MT, Tikhonova AN, Guillamot-Ruano M, Cayanan G, Yeaton A, Robbins G, Obeng EA, Tsirigos A, et al. An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia. Nature Cancer. PMID 36581735 DOI: 10.1038/s43018-022-00480-0  0.528
2022 Yeaton A, Cayanan G, Loghavi S, Dolgalev I, Leddin EM, Loo CE, Torabifard H, Nicolet D, Wang J, Corrigan K, Paraskevopoulou V, Starczynowski DT, Wang E, Abdel-Wahab O, Viny AD, ... ... Tsirigos A, et al. The impact of inflammation-induced tumor plasticity during myeloid transformation. Cancer Discovery. PMID 35924979 DOI: 10.1158/2159-8290.CD-21-1146  0.667
2022 Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner TP, Rabinovich-Nikitin I, Ouchida AT, Margulets V, Nordstrøm LU, Riley JS, Dolgalev I, Chen Y, Wittig AJH, Pekson R, Mathew C, ... ... Tsirigos A, et al. Modulating mitofusins to control mitochondrial function and signaling. Nature Communications. 13: 3775. PMID 35798717 DOI: 10.1038/s41467-022-31324-1  0.542
2022 Carcamo S, Nguyen CB, Grossi E, Filipescu D, Alpsoy A, Dhiman A, Sun D, Narang S, Imig J, Martin TC, Parsons R, Aifantis I, Tsirigos A, Aguirre-Ghiso JA, Dykhuizen EC, et al. Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma. Cell Reports. 39: 110637. PMID 35385731 DOI: 10.1016/j.celrep.2022.110637  0.559
2022 Moubarak RS, de Pablos-Aragoneses A, Ortiz-Barahona V, Gong Y, Gowen M, Dolgalev I, Shadaloey SAA, Argibay D, Karz A, Von Itter R, Vega-Sáenz de Miera EC, Sokolova E, Darvishian F, Tsirigos A, Osman I, et al. The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis. Science Advances. 8: eabi7127. PMID 35179962 DOI: 10.1126/sciadv.abi7127  0.618
2022 Thandapani P, Kloetgen A, Witkowski MT, Glytsou C, Lee AK, Wang E, Wang J, LeBoeuf SE, Avrampou K, Papagiannakopoulos T, Tsirigos A, Aifantis I. Valine tRNA levels and availability regulate complex I assembly in leukaemia. Nature. 601: 428-433. PMID 34937946 DOI: 10.1038/s41586-021-04244-1  0.543
2021 Kim RH, Nomikou S, Coudray N, Jour G, Dawood Z, Hong R, Esteva E, Sakellaropoulos T, Donnelly D, Moran U, Hatzimemos A, Weber JS, Razavian N, Aifantis I, Fenyo D, ... ... Tsirigos A, et al. Deep learning and pathomics analyses reveal cell nuclei as important features for mutation prediction of BRAF-mutated melanomas. The Journal of Investigative Dermatology. PMID 34757067 DOI: 10.1016/j.jid.2021.09.034  0.472
2021 Hu H, Khodadadi-Jamayran A, Dolgalev I, Cho H, Badri S, Chiriboga LA, Zeck B, Lopez De Rodas Gregorio M, Dowling CM, Labbe K, Deng J, Chen T, Zhang H, Zappile P, Chen Z, ... ... Tsirigos A, et al. Targeting the Atf7ip-Setdb1 complex augments antitumor immunity by boosting tumor immunogenicity. Cancer Immunology Research. PMID 34462284 DOI: 10.1158/2326-6066.CIR-21-0543  0.613
2021 Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng D, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, ... ... Tsirigos A, et al. ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. Nature Cancer. 2: 503-514. PMID 34142094 DOI: 10.1038/s43018-021-00208-6  0.538
2021 Wang E, Zhou H, Nadorp B, Cayanan G, Chen X, Yeaton AH, Nomikou S, Witkowski MT, Narang S, Kloetgen A, Thandapani P, Ravn-Boess N, Tsirigos A, Aifantis I. Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation. Cell Stem Cell. PMID 33450187 DOI: 10.1016/j.stem.2020.12.005  0.576
2020 Cui X, Ma C, Vasudevaraja V, Serrano J, Tong J, Peng Y, Delorenzo M, Shen G, Frenster J, Morales RT, Qian W, Tsirigos A, Chi AS, Jain R, Kurz SC, et al. Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapy. Elife. 9. PMID 32909947 DOI: 10.7554/Elife.52253  0.3
2020 Moro L, Simoneschi D, Kurz E, Arbini AA, Jang S, Guaragnella N, Giannattasio S, Wang W, Chen YA, Pires G, Dang A, Hernandez E, Kapur P, Mishra A, Tsirigos A, et al. Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. Nature Cell Biology. PMID 32839549 DOI: 10.1038/S41556-020-0560-6  0.335
2020 Witkowski MT, Dolgalev I, Evensen NA, Ma C, Chambers T, Roberts KG, Sreeram S, Dai Y, Tikhonova AN, Lasry A, Qu C, Pei D, Cheng C, Robbins GA, Pierro J, ... ... Tsirigos A, et al. Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia. Cancer Cell. PMID 32470390 DOI: 10.1016/J.Ccell.2020.04.015  0.686
2020 Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Guttierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, ... ... Tsirigos A, et al. Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia. Cancer Discovery. PMID 32444465 DOI: 10.1158/2159-8290.Cd-19-1436  0.6
2020 Nishana M, Ha C, Rodriguez-Hernaez J, Ranjbaran A, Chio E, Nora EP, Badri SB, Kloetgen A, Bruneau BG, Tsirigos A, Skok JA. Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation. Genome Biology. 21: 108. PMID 32393311 DOI: 10.1186/S13059-020-02024-0  0.319
2020 Pierro J, Saliba J, Narang S, Sethia G, Saint Fleur-Lominy S, Chowdhury A, Qualls A, Fay H, Kilberg HL, Moriyama T, Fuller TJ, Teachey DT, Schmiegelow K, Yang JJ, Loh ML, ... ... Tsirigos A, et al. The NSD2 p.E1099K Mutation is Enriched at Relapse and Confers Drug Resistance in a Cell Context Dependent Manner in Pediatric Acute Lymphoblastic Leukemia. Molecular Cancer Research : McR. PMID 32332049 DOI: 10.1158/1541-7786.Mcr-20-0092  0.361
2020 Kloetgen A, Thandapani P, Ntziachristos P, Ghebrechristos Y, Nomikou S, Lazaris C, Chen X, Hu H, Bakogianni S, Wang J, Fu Y, Boccalatte F, Zhong H, Paietta E, Trimarchi T, ... ... Tsirigos A, et al. Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia. Nature Genetics. PMID 32203470 DOI: 10.1038/S41588-020-0602-9  0.586
2020 Lazaris C, Aifantis I, Tsirigos A. On Epigenetic Plasticity and Genome Topology. Trends in Cancer. 6: 177-180. PMID 32101721 DOI: 10.1016/J.Trecan.2020.01.006  0.555
2020 Hanniford D, Ulloa-Morales A, Karz A, Berzoti-Coelho MG, Moubarak RS, Sánchez-Sendra B, Kloetgen A, Davalos V, Imig J, Wu P, Vasudevaraja V, Argibay D, Lilja K, Tabaglio T, Monteagudo C, ... ... Tsirigos A, et al. Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. Cancer Cell. 37: 55-70.e15. PMID 31935372 DOI: 10.1016/J.Ccell.2019.12.007  0.565
2020 Hatzioannou A, Banos A, Sakelaropoulos T, Fedonidis C, Vidali MS, Köhne M, Händler K, Boon L, Henriques A, Koliaraki V, Georgiadis P, Zoidakis J, Termentzi A, Beyer M, Chavakis T, ... ... Tsirigos A, et al. An intrinsic role of IL-33 in T cell-mediated tumor immunoevasion. Nature Immunology. 21: 75-85. PMID 31844326 DOI: 10.1038/S41590-019-0555-2  0.335
2020 Adorno Febles VR, Adeegbe D, Ahsan A, Wu J, Khodadad-Jamayran A, Lepor H, Wysock J, Taneja S, Huang WC, Balar AV, Melamed J, Deng F, Ren Q, Tsirigos A, Kufe DW, et al. Immunosuppressive milieu of high-risk localized prostate cancer. Journal of Clinical Oncology. 38: 344-344. DOI: 10.1200/Jco.2020.38.6_Suppl.344  0.335
2020 Pierro J, Saliba J, Narang S, Sethia G, Fleur-Lominy SS, Chowdhury A, Moriyama T, Schmiegelow K, Yang JJ, Loh ML, Brown PA, Zhang J, Ma X, Tsirigos A, Evensen NA, et al. Abstract 5399: The NSD2 p.E1099K mutation is enriched at relapse and confers drug resistance in a cell context dependent manner in pediatric acute lymphoblastic leukemia Cancer Research. 80: 5399-5399. DOI: 10.1158/1538-7445.Am2020-5399  0.38
2020 Doudican N, Frazzette N, Khodadadi-Jamayran A, Tsirigos A, Carucci J. 137 Decreased cytotoxic T cells, decreased cytotoxic/regulatory T-cell ratio, and decreased TCR clonality are associated with increased numbers of primary cutaneous squamous cell carcinomas in solid organ transplant recipients Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.140  0.319
2019 Halaby MJ, Hezaveh K, Lamorte S, Ciudad MT, Kloetgen A, MacLeod BL, Guo M, Chakravarthy A, Medina TDS, Ugel S, Tsirigos A, Bronte V, Munn DH, Pugh TJ, De Carvalho DD, et al. GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment. Science Immunology. 4. PMID 31836669 DOI: 10.1126/Sciimmunol.Aax8189  0.404
2019 Sakellaropoulos T, Vougas K, Narang S, Koinis F, Kotsinas A, Polyzos A, Moss TJ, Piha-Paul S, Zhou H, Kardala E, Damianidou E, Alexopoulos LG, Aifantis I, Townsend PA, Panayiotidis MI, ... ... Tsirigos A, et al. A Deep Learning Framework for Predicting Response to Therapy in Cancer. Cell Reports. 29: 3367-3373.e4. PMID 31825821 DOI: 10.1016/J.Celrep.2019.11.017  0.521
2019 Li F, Huang Q, Luster TA, Hu H, Zhang H, Ng WL, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling CM, Bagdatlioglu E, ... ... Tsirigos A, et al. In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma. Cancer Discovery. PMID 31744829 DOI: 10.1158/2159-8290.Cd-19-0780  0.367
2019 Bledea R, Vasudevaraja V, Patel S, Stafford J, Serrano J, Esposito G, Tredwin LM, Goodman N, Kloetgen A, Golfinos JG, Zagzag D, Weigelt B, Iafrate AJ, Sulman EP, Chi AS, ... ... Tsirigos A, et al. Functional and topographic effects on DNA methylation in IDH1/2 mutant cancers. Scientific Reports. 9: 16830. PMID 31727977 DOI: 10.1038/S41598-019-53262-7  0.334
2019 Yusufova N, Teater MR, Soshnev A, Kloetgen A, Osunsade A, Conway J, Doane A, Skoultchi A, Tsirigos A, David Y, Allis CD, Cesarman E, Melnick A. Histone 1 Mutations Drive Lymphomagenesis By Inducing Primitive Stem Cell Functions and Epigenetic Instructions through Profound 3D Re-Organization of the B-Cell Genome. Blood. 134: 23. PMID 31723979 DOI: 10.1182/Blood-2019-127774  0.357
2019 Lhoumaud P, Badri S, Rodriguez-Hernaez J, Sakellaropoulos T, Sethia G, Kloetgen A, Cornwell M, Bhattacharyya S, Ay F, Bonneau R, Tsirigos A, Skok JA. NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains. Nature Communications. 10: 4843. PMID 31649247 DOI: 10.1038/S41467-019-12811-4  0.338
2019 Di Giammartino DC, Kloetgen A, Polyzos A, Liu Y, Kim D, Murphy D, Abuhashem A, Cavaliere P, Aronson B, Shah V, Dephoure N, Stadtfeld M, Tsirigos A, Apostolou E. KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks. Nature Cell Biology. PMID 31548608 DOI: 10.1038/S41556-019-0390-6  0.398
2019 Saldaña-Meyer R, Rodriguez-Hernaez J, Escobar T, Nishana M, Jácome-López K, Nora EP, Bruneau BG, Tsirigos A, Furlan-Magaril M, Skok J, Reinberg D. RNA Interactions Are Essential for CTCF-Mediated Genome Organization. Molecular Cell. PMID 31522988 DOI: 10.1016/J.Molcel.2019.08.015  0.321
2019 Kloetgen A, Thandapani P, Tsirigos A, Aifantis I. 3D Chromosomal Landscapes in Hematopoiesis and Immunity. Trends in Immunology. PMID 31422902 DOI: 10.1016/J.It.2019.07.003  0.57
2019 Guillamot M, Ouazia D, Dolgalev I, Yeung ST, Kourtis N, Dai Y, Corrigan K, Zea-Redondo L, Saraf A, Florens L, Washburn MP, Tikhonova AN, Malumbres M, Gong Y, Tsirigos A, et al. The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation. Nature Immunology. PMID 31406379 DOI: 10.1038/S41590-019-0454-6  0.691
2019 Vougas K, Sakelaropoulos T, Kotsinas A, Foukas GP, Ntargaras A, Koinis F, Polyzos A, Myrianthopoulos V, Zhou H, Narang S, Georgoulias V, Alexopoulos L, Aifantis I, Townsend PA, Sfikakis P, ... ... Tsirigos A, et al. Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining. Pharmacology & Therapeutics. 107395. PMID 31374225 DOI: 10.1016/J.Pharmthera.2019.107395  0.513
2019 Yu M, Scherwitzl I, Opp S, Tsirigos A, Meruelo D. Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody. Journal For Immunotherapy of Cancer. 7: 185. PMID 31307539 DOI: 10.1186/S40425-019-0664-3  0.316
2019 Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, ... ... Tsirigos A, et al. Author Correction: The bone marrow microenvironment at single-cell resolution. Nature. PMID 31296938 DOI: 10.1038/S41586-019-1394-X  0.667
2019 Lignitto L, LeBoeuf SE, Homer H, Jiang S, Askenazi M, Karakousi TR, Pass HI, Bhutkar AJ, Tsirigos A, Ueberheide B, Sayin VI, Papagiannakopoulos T, Pagano M. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Cell. PMID 31257023 DOI: 10.1016/J.Cell.2019.06.003  0.301
2019 Chen X, Glytsou C, Zhou H, Narang S, Reyna DE, Lopez A, Sakellaropoulos T, Gong Y, Kloetgen A, Yap YS, Wang E, Gavathiotis E, Tsirigos A, Tibes R, Aifantis I. Targeting mitochondrial structure sensitizes acute myeloid leukemia to Venetoclax treatment. Cancer Discovery. PMID 31048321 DOI: 10.1158/2159-8290.Cd-19-0117  0.547
2019 Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, ... ... Tsirigos A, et al. The bone marrow microenvironment at single-cell resolution. Nature. PMID 30971824 DOI: 10.1038/S41586-019-1104-8  0.701
2019 Tetz G, Vikina D, Brown S, Zappile P, Dolgalev I, Tsirigos A, Heguy A, Tetz V. Draft Genome Sequence of Streptococcus halitosis sp. nov., Isolated from the Dorsal Surface of the Tongue of a Patient with Halitosis. Microbiology Resource Announcements. 8. PMID 30701262 DOI: 10.1128/MRA.01704-18  0.532
2019 Deng J, Thennavan A, Pan Y, Dolgalev I, Chen T, Silver H, Harris M, Pyon V, Li F, Lee C, Tsirigos A, Rothenberg E, Perou CM, Wong K. Abstract 3223: Overcome LKB1 mutated cancer resistance to anti-PD1 treatment Cancer Research. 79: 3223-3223. DOI: 10.1158/1538-7445.Am2019-3223  0.625
2019 Doudican N, Santana A, Felsen D, Khodadadi-Jamayran A, Tsirigos A, Carucci J. 135 Defining the T cell landscape and neoantigens via T-cell receptor sequencing and gene expression profiling in cutaneous squamous cell carcinoma Journal of Investigative Dermatology. 139: S24. DOI: 10.1016/J.Jid.2019.03.211  0.337
2019 Witkowski M, Dolgalev I, Evensen N, Roberts K, Sreeram S, Dai Y, Tikhonova A, Loomis C, Mullighan C, Tsirigos A, Carroll W, Aifantis I. 2029 - THE RELAPSED B-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA IMMUNE MICROENVIRONMENT Experimental Hematology. 76: S49. DOI: 10.1016/J.Exphem.2019.06.301  0.704
2018 Xiong X, Schober M, Tassone E, Khodadadi-Jamayran A, Sastre-Perona A, Zhou H, Tsirigos A, Shen S, Chang M, Melamed J, Ossowski L, Wilson EL. KLF4, A Gene Regulating Prostate Stem Cell Homeostasis, Is a Barrier to Malignant Progression and Predictor of Good Prognosis in Prostate Cancer. Cell Reports. 25: 3006-3020.e7. PMID 30540935 DOI: 10.1016/J.Celrep.2018.11.065  0.359
2018 Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, et al. Cell surface Notch ligand DLL3 is a therapeutic target in isocitrate dehydrogenase mutant glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30397180 DOI: 10.1158/1078-0432.Ccr-18-2312  0.305
2018 Adeegbe DO, Liu S, Hattersley M, Bowden M, Zhou CW, Li S, Vlahos R, Grondine M, Dolgalev I, Ivanova E, Quinn MM, Gao P, Hammerman PS, Bradner JE, Diehl JA, ... ... Tsirigos A, et al. BET bromodomain inhibition cooperates with PD-1 blockade to facilitate antitumor response in Kras-mutant non-small cell lung cancer. Cancer Immunology Research. PMID 30087114 DOI: 10.1158/2326-6066.Cir-18-0077  0.63
2018 Kourtis N, Lazaris C, Hockemeyer K, Balandrán JC, Jimenez AR, Mullenders J, Gong Y, Trimarchi T, Bhatt K, Hu H, Shrestha L, Ambesi-Impiombato A, Kelliher M, Paietta E, Chiosis G, ... ... Tsirigos A, et al. Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia. Nature Medicine. PMID 30038221 DOI: 10.1038/S41591-018-0105-8  0.576
2018 Smith-Raska MR, Arenzana TL, D'Cruz LM, Khodadadi-Jamayran A, Tsirigos A, Goldrath AW, Reizis B. The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation. Frontiers in Immunology. 9: 1482. PMID 30022979 DOI: 10.3389/Fimmu.2018.01482  0.384
2018 Shekhar A, Lin X, Lin B, Liu FY, Zhang J, Khodadadi-Jamayran A, Tsirigos A, Bu L, Fishman GI, Park DS. ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes. Scientific Reports. 8: 9944. PMID 29967479 DOI: 10.1038/S41598-018-28239-7  0.309
2018 Kirkling ME, Cytlak U, Lau CM, Lewis KL, Resteu A, Khodadadi-Jamayran A, Siebel CW, Salmon H, Merad M, Tsirigos A, Collin M, Bigley V, Reizis B. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Reports. 23: 3658-3672.e6. PMID 29925006 DOI: 10.1016/J.Celrep.2018.05.068  0.358
2018 Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, ... ... Tsirigos A, et al. Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nature Immunology. PMID 29760532 DOI: 10.1038/S41590-018-0107-1  0.336
2018 Gong Y, Lazaris C, Sakellaropoulos T, Lozano A, Kambadur P, Ntziachristos P, Aifantis I, Tsirigos A. Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries. Nature Communications. 9: 542. PMID 29416042 DOI: 10.1038/S41467-018-03017-1  0.53
2018 Sen R, Dolgalev I, Bayin NS, Heguy A, Tsirigos A, Placantonakis DG. Single-Cell RNA Sequencing of Glioblastoma Cells. Methods in Molecular Biology (Clifton, N.J.). 1741: 151-170. PMID 29392698 DOI: 10.1007/978-1-4939-7659-1_12  0.598
2018 Nancy P, Siewiera J, Rizzuto G, Tagliani E, Osokine I, Manandhar P, Dolgalev I, Clementi C, Tsirigos A, Erlebacher A. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. The Journal of Clinical Investigation. 128: 233-247. PMID 29202469 DOI: 10.1172/Jci95937  0.604
2018 Kloetgen A, Serrano J, Patel S, Bowman C, Shen G, Zagzag D, Karajannis MA, Golfinos JG, Placantonakis D, Tsirigos A, Chi AS, Snuderl M. Abstract 3658: DNA methylation of circulating tumor educated leukocytes predicts IDH1/2 mutation status in adult patients with diffuse gliomas Cancer Research. 78: 3658-3658. DOI: 10.1158/1538-7445.Am2018-3658  0.32
2018 Thandapani P, Kloetgen A, Lazaris C, Chen X, Ntziachristos P, Tsirigos A, Aifantis I. Abstract 2998: Dynamic 3d chromosomal landscapes in acute leukemia Cancer Research. 78: 2998-2998. DOI: 10.1158/1538-7445.Am2018-2998  0.607
2017 Brown JA, Yonekubo Y, Hanson N, Sastre-Perona A, Basin A, Rytlewski JA, Dolgalev I, Meehan S, Tsirigos A, Beronja S, Schober M. TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. Cell Stem Cell. 21: 650-664.e8. PMID 29100014 DOI: 10.1016/J.Stem.2017.10.001  0.637
2017 Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, ... ... Tsirigos A, et al. Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2. Cell Reports. 21: 1267-1280. PMID 29091765 DOI: 10.1016/J.Celrep.2017.10.009  0.367
2017 Tetz G, Vecherkovskaya M, Zappile P, Dolgalev I, Tsirigos A, Heguy A, Tetz V. Complete Genome Sequence of Kluyvera intestini sp. nov., Isolated from the Stomach of a Patient with Gastric Cancer. Genome Announcements. 5. PMID 29074664 DOI: 10.1128/Genomea.01184-17  0.574
2017 Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, ... Tsirigos A, et al. Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. Oncotarget. 8: 64932-64953. PMID 29029402 DOI: 10.18632/Oncotarget.18117  0.627
2017 Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, Martín MT, Guillamot M, ... ... Tsirigos A, et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. Cell. PMID 28823558 DOI: 10.1016/J.Cell.2017.07.032  0.715
2017 Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, ... Tsirigos A, et al. Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. Oncotarget. PMID 28586758 DOI: 10.18632/oncotarget.18117  0.592
2017 Gong Y, Huang HT, Liang Y, Trimarchi T, Aifantis I, Tsirigos A. lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets. Bmc Genomics. 18: 434. PMID 28583068 DOI: 10.1186/S12864-017-3817-0  0.532
2017 Rigoutsos I, Lee SK, Nam SY, Anfossi S, Pasculli B, Pichler M, Jing Y, Rodriguez-Aguayo C, Telonis AG, Rossi S, Ivan C, Catela Ivkovic T, Fabris L, Clark PM, Ling H, ... ... Tsirigos A, et al. N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration. Genome Biology. 18: 98. PMID 28535802 DOI: 10.1186/S13059-017-1224-0  0.308
2017 Strikoudis A, Lazaris C, Ntziachristos P, Tsirigos A, Aifantis I. Opposing functions of H2BK120 ubiquitylation and H3K79 methylation in the regulation of pluripotency by the Paf1 complex. Cell Cycle (Georgetown, Tex.). 0. PMID 28272987 DOI: 10.1080/15384101.2017.1295194  0.596
2017 Lazaris C, Kelly S, Ntziachristos P, Aifantis I, Tsirigos A. HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking. Bmc Genomics. 18: 22. PMID 28056762 DOI: 10.1186/S12864-016-3387-6  0.505
2017 Fleur-Lominy SS, Bhatla T, Kelly S, Vasudevaraja V, Tsirigos A, Carroll WL. Genomic and Epigenetic Effects of DNA Methyltransferase Inhibition in Acute Lymphoblastic Leukemia Blood. 130: 2479-2479. DOI: 10.1182/Blood.V130.Suppl_1.2479.2479  0.356
2017 Modrek A, Golub D, Khan T, Prado J, Bowman C, Deng J, Zhang G, Rocha P, Raviram R, Lazaris H, Kader M, Dhaliwal J, Chi A, Golfinos J, Tsirigos A, et al. LGG-11. LOW-GRADE ASTROCYTOMA CORE MUTATIONS IN IDH1, P53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF HUMAN NEURAL STEM CELLS VIA EPIGENETIC REPRESSION OF SOX2 Neuro-Oncology. 19: iv35-iv35. DOI: 10.1093/Neuonc/Nox083.144  0.335
2016 Gutiérrez GD, Bender AS, Cirulli V, Mastracci TL, Kelly SM, Tsirigos A, Kaestner KH, Sussel L. Pancreatic β cell identity requires continual repression of non-β cell programs. The Journal of Clinical Investigation. PMID 27941248 DOI: 10.1172/Jci88017  0.318
2016 Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I. Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nature Cell Biology. PMID 27749823 DOI: 10.1038/Ncb3424  0.715
2016 Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, Sánchez-Díaz M, Wang K, Kayembe C, Zhang N, Amoasii L, ... ... Tsirigos A, et al. MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell. PMID 27570068 DOI: 10.1016/J.Stem.2016.08.004  0.595
2016 Kannan KS, Tsirigos A, Serrano J, Forrester LA, Faustin A, Thomas C, Capper D, Hovestadt V, Pfister SM, Jones DTW, Sill M, Schrimpf D, Deimling Av, Heguy A, Gardner SL, et al. Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management Clinical Cancer Research. 22: 11-11. DOI: 10.1158/1557-3265.Pmsclingen15-11  0.309
2016 Modrek A, Golub D, Khan T, Zhang G, Kader M, Bowman C, Prado J, Bayin NS, Frenster J, Lhakhang T, Heguy A, Dankert J, Tsirigos A, Snuderl M, Neubert T, et al. STMC-21. ASTROCYTOMA MUTATIONS IDH1, p53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF NEURAL STEM CELLS VIA Sox2 Neuro-Oncology. 18: vi187-vi187. DOI: 10.1093/Neuonc/Now212.784  0.307
2016 Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Schrewe H, Tsirigos A, Zon L, Aifantis I. Med12 is an essential regulator of enhancer dynamics in hematopoietic stem cells Experimental Hematology. 44: S57. DOI: 10.1016/J.Exphem.2016.06.086  0.565
2015 Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, et al. Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms. The Journal of Experimental Medicine. PMID 26438359 DOI: 10.1084/Jem.20151323  0.619
2015 Pitt LA, Tikhonova AN, Hu H, Trimarchi T, King B, Gong Y, Sanchez-Martin M, Tsirigos A, Littman DR, Ferrando AA, Morrison SJ, Fooksman DR, Aifantis I, Schwab SR. CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance. Cancer Cell. 27: 755-68. PMID 26058075 DOI: 10.1016/J.Ccell.2015.05.002  0.522
2015 Kourtis N, Moubarak RS, Aranda-Orgilles B, Lui K, Aydin IT, Trimarchi T, Darvishian F, Salvaggio C, Zhong J, Bhatt K, Chen EI, Celebi JT, Lazaris C, Tsirigos A, Osman I, et al. FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification. Nature Cell Biology. 17: 322-32. PMID 25720964 DOI: 10.1038/Ncb3121  0.581
2015 Pitt LA, Tikhonova AN, Trimarchi T, King B, Hu H, Gong Y, Tsirigos A, Sanchez-Martin M, Littman DR, Ferrando A, Morrison SJ, Fooksman DR, Aifantis I, Schwab S. Abstract A06: The chemokine receptor CXCR4 is essential for the maintenance of T cell acute lymphoblastic leukemia. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A06  0.536
2014 Vidal SE, Amlani B, Chen T, Tsirigos A, Stadtfeld M. Combinatorial modulation of signaling pathways reveals cell-type-specific requirements for highly efficient and synchronous iPSC reprogramming. Stem Cell Reports. 3: 574-84. PMID 25358786 DOI: 10.1016/J.Stemcr.2014.08.003  0.364
2014 Di Micco R, Fontanals-Cirera B, Low V, Ntziachristos P, Yuen SK, Lovell CD, Dolgalev I, Yonekubo Y, Zhang G, Rusinova E, Gerona-Navarro G, Cañamero M, Ohlmeyer M, Aifantis I, Zhou MM, ... Tsirigos A, et al. Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes. Cell Reports. 9: 234-47. PMID 25263550 DOI: 10.1016/J.Celrep.2014.08.055  0.716
2014 Ntziachristos P, Tsirigos A, Welstead GG, Trimarchi T, Bakogianni S, Xu L, Loizou E, Holmfeldt L, Strikoudis A, King B, Mullenders J, Becksfort J, Nedjic J, Paietta E, Tallman MS, et al. Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia. Nature. 514: 513-7. PMID 25132549 DOI: 10.1038/Nature13605  0.598
2014 Trimarchi T, Bilal E, Ntziachristos P, Fabbri G, Dalla-Favera R, Tsirigos A, Aifantis I. Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia. Cell. 158: 593-606. PMID 25083870 DOI: 10.1016/J.Cell.2014.05.049  0.59
2014 Siegle JM, Basin A, Sastre-Perona A, Yonekubo Y, Brown J, Sennett R, Rendl M, Tsirigos A, Carucci JA, Schober M. SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma. Nature Communications. 5: 4511. PMID 25077433 DOI: 10.1038/Ncomms5511  0.375
2014 Lisanti MP, Tsirigos A, Pavlides S, Reeves KJ, Peiris-Pagès M, Chadwick AL, Sanchez-Alvarez R, Lamb R, Howell A, Martinez-Outschoorn UE, Sotgia F. JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention. Cell Cycle (Georgetown, Tex.). 13: 580-99. PMID 24434780 DOI: 10.4161/Cc.27379  0.335
2014 Ntziachristos P, Tsirigos A, Welstead G, Trimarchi T, Holmfeldt L, Satoh T, Paietta EM, Tallman MS, Rowe JM, Tonon G, Becksfort J, Kruidenier L, Prinjha RK, Van Vlierberghe P, Jaenisch R, et al. An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia Blood. 124: 56-56. DOI: 10.1182/Blood.V124.21.56.56  0.625
2013 Ntziachristos P, Tsirigos A, Trimarchi T, Loizou E, Luyao X, Vlierberghe PV, King B, Welstead G, Mullighan C, Jaenisch R, Ferrando A, Aifantis I. Abstract A07: Characterizing the specific oncogenic and tumor suppressor roles of H3K27me3 epigenetic modulators in T cell leukemia Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A07  0.588
2012 Sotgia F, Whitaker-Menezes D, Martinez-Outschoorn UE, Salem AF, Tsirigos A, Lamb R, Sneddon S, Hulit J, Howell A, Lisanti MP. Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. Cell Cycle (Georgetown, Tex.). 11: 4390-401. PMID 23172368 DOI: 10.4161/Cc.22777  0.333
2012 Bonuccelli G, Castello-Cros R, Capozza F, Martinez-Outschoorn UE, Lin Z, Tsirigos A, Xuanmao J, Whitaker-Menezes D, Howell A, Lisanti MP, Sotgia F. The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis. Cell Cycle (Georgetown, Tex.). 11: 3972-82. PMID 23047602 DOI: 10.4161/Cc.22227  0.395
2012 Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle (Georgetown, Tex.). 11: 2285-302. PMID 22684298 DOI: 10.4161/Cc.20718  0.365
2012 Ntziachristos P, Tsirigos A, Van Vlierberghe P, Nedjic J, Trimarchi T, Flaherty MS, Ferres-Marco D, da Ros V, Tang Z, Siegle J, Asp P, Hadler M, Rigo I, De Keersmaecker K, Patel J, et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nature Medicine. 18: 298-301. PMID 22237151 DOI: 10.1038/Nm.2651  0.606
2012 Ertel A, Tsirigos A, Whitaker-Menezes D, Birbe RC, Pavlides S, Martinez-Outschoorn UE, Pestell RG, Howell A, Sotgia F, Lisanti MP. Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 11: 253-63. PMID 22234241 DOI: 10.4161/Cc.11.2.19006  0.307
2011 Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. Cell Cycle (Georgetown, Tex.). 10: 4047-64. PMID 22134189 DOI: 10.4161/Cc.10.23.18151  0.361
2011 Witkiewicz AK, Kline J, Queenan M, Brody JR, Tsirigos A, Bilal E, Pavlides S, Ertel A, Sotgia F, Lisanti MP. Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers. Cell Cycle (Georgetown, Tex.). 10: 1794-809. PMID 21521946 DOI: 10.4161/Cc.10.11.15675  0.389
2011 Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle (Georgetown, Tex.). 10: 1271-86. PMID 21512313 DOI: 10.4161/Cc.10.8.15330  0.395
2011 Witkiewicz AK, Kline J, Queenan M, Brody J, Sotgia F, Tsirigos A, Lisanti MP. Abstract 1510: Transcriptional profiling of a lethal breast cancer tumor microenvironment Cancer Research. 71: 1510-1510. DOI: 10.1158/1538-7445.Am2011-1510  0.393
2010 Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, Tsirigos A, Migneco G, Witkiewicz A, Balliet R, Mercier I, Wang C, Flomenberg N, Howell A, Lin Z, et al. The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox. Cell Cycle (Georgetown, Tex.). 9: 4297-306. PMID 21051947 DOI: 10.4161/Cc.9.21.13817  0.358
2010 Pavlides S, Tsirigos A, Migneco G, Whitaker-Menezes D, Chiavarina B, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. Cell Cycle (Georgetown, Tex.). 9: 3485-505. PMID 20861672 DOI: 10.4161/Cc.9.17.12721  0.324
2010 Lisanti MP, Martinez-Outschoorn UE, Chiavarina B, Pavlides S, Whitaker-Menezes D, Tsirigos A, Witkiewicz A, Lin Z, Balliet R, Howell A, Sotgia F. Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment. Cancer Biology & Therapy. 10: 537-42. PMID 20861671 DOI: 10.4161/Cbt.10.6.13370  0.375
2010 Bonuccelli G, Tsirigos A, Whitaker-Menezes D, Pavlides S, Pestell RG, Chiavarina B, Frank PG, Flomenberg N, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 9: 3506-14. PMID 20818174 DOI: 10.4161/Cc.9.17.12731  0.342
2010 Migneco G, Whitaker-Menezes D, Chiavarina B, Castello-Cros R, Pavlides S, Pestell RG, Fatatis A, Flomenberg N, Tsirigos A, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling. Cell Cycle (Georgetown, Tex.). 9: 2412-22. PMID 20562527 DOI: 10.4161/Cc.9.12.11989  0.347
2010 Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation. Cell Cycle (Georgetown, Tex.). 9: 2201-19. PMID 20519932 DOI: 10.4161/Cc.9.11.11848  0.389
2010 Laurent L, Wong E, Li G, Huynh T, Tsirigos A, Ong CT, Low HM, Kin Sung KW, Rigoutsos I, Loring J, Wei CL. Dynamic changes in the human methylome during differentiation. Genome Research. 20: 320-31. PMID 20133333 DOI: 10.1101/Gr.101907.109  0.362
2006 Rigoutsos I, Huynh T, Miranda K, Tsirigos A, McHardy A, Platt D. Short blocks from the noncoding parts of the human genome have instances within nearly all known genes and relate to biological processes. Proceedings of the National Academy of Sciences of the United States of America. 103: 6605-10. PMID 16636294 DOI: 10.1073/Pnas.0601688103  0.328
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