Brian W. Freie, Ph.D. - Publications

Affiliations: 
2003 Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Oncology, Genetics, Cell Biology

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Freie B, Carroll PA, Varnum-Finney BJ, Ramsey EL, Ramani V, Bernstein I, Eisenman RN. A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies. Genes & Development. PMID 38565249 DOI: 10.1101/gad.351292.123  0.327
2023 Freie B, Carroll PA, Varnum-Finney BJ, Ramani V, Bernstein I, Eisenman RN. A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies. Biorxiv : the Preprint Server For Biology. PMID 37961183 DOI: 10.1101/2023.10.23.563660  0.328
2019 Mathsyaraja H, Freie B, Cheng PF, Babaeva E, Catchpole JT, Janssens D, Henikoff S, Eisenman RN. deletion destabilizes MYC protein and abrogates Eµ- lymphomagenesis. Genes & Development. PMID 31395740 DOI: 10.1101/Gad.325878.119  0.319
2008 Park H, Staehling-Hampton K, Appleby MW, Brunkow ME, Habib T, Zhang Y, Ramsdell F, Liggitt HD, Freie B, Tsang M, Carlson G, Friend S, Frevert C, Iritani BM. A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity. The Journal of Experimental Medicine. 205: 2899-913. PMID 19015308 DOI: 10.1084/Jem.20080340  0.361
2005 Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy. Blood. 105: 3465-71. PMID 15644418 DOI: 10.1182/Blood-2004-06-2483  0.476
2004 Freie BW, Ciccone SL, Li X, Plett PA, Orschell CM, Srour EF, Hanenberg H, Schindler D, Lee SH, Clapp DW. A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint. The Journal of Biological Chemistry. 279: 50986-93. PMID 15377654 DOI: 10.1074/Jbc.M407160200  0.424
2004 Park SJ, Ciccone SL, Beck BD, Hwang B, Freie B, Clapp DW, Lee SH. Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. The Journal of Biological Chemistry. 279: 30053-9. PMID 15138265 DOI: 10.1074/Jbc.M403527200  0.342
2004 Li X, Yang Y, Yuan J, Hong P, Freie B, Orazi A, Haneline LS, Clapp DW. Continuous in vivo infusion of interferon-gamma (IFN-γ) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc-/- mice Blood. 104: 1204-1209. PMID 15113761 DOI: 10.1182/Blood-2004-03-1094  0.41
2004 Park SJ, Ciccone SL, Freie B, Kurimasa A, Chen DJ, Li GC, Clapp DW, Lee SH. A positive role for the Ku complex in DNA replication following strand break damage in mammals. The Journal of Biological Chemistry. 279: 6046-55. PMID 14617623 DOI: 10.1074/Jbc.M311054200  0.424
2003 Freie B, Li X, Ciccone SL, Nawa K, Cooper S, Vogelweid C, Schantz L, Haneline LS, Orazi A, Broxmeyer HE, Lee SH, Clapp DW. Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis. Blood. 102: 4146-52. PMID 12855557 DOI: 10.1182/Blood-2003-03-0971  0.386
2003 Li X, Plett PA, Yang Y, Hong P, Freie B, Srour EF, Orschell CM, Clapp DW, Haneline LS. Fanconi anemia type C-deficient hematopoietic stem/progenitor cells exhibit aberrant cell cycle control. Blood. 102: 2081-4. PMID 12763929 DOI: 10.1182/Blood-2003-02-0536  0.514
2001 Kelley MR, Tritt R, Xu Y, New S, Freie B, Clapp DW, Deutsch WA. The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents Mutation Research - Dna Repair. 485: 107-119. PMID 11182542 DOI: 10.1016/S0921-8777(00)00067-7  0.386
2000 Freie BW, Ciccone S, Nawa K, Lee SH, Wade Clapp D. The fanconi anemia complementation group c protein is required for normal cell cycle arrest induced by ionizing irradiation Blood. 96.  0.473
1996 Freie BW, Dutt P, Clapp DW. Correction of Fanconi anemia type C phenotypic abnormalities using a clinically suitable retroviral vector infection protocol Cell Transplantation. 5: 385-393. PMID 8727007 DOI: 10.1016/0963-6897(95)02022-5  0.476
1996 Lu L, Ge Y, Li ZH, Freie B, Clapp DW, Broxmeyer HE. CD34 stem/progenitor cells purified from cryopreserved normal cord blood can be transduced with high efficiency by a retroviral vector and expanded ex vivo with stable integration and expression of Fanconi anemia complementation C gene. Cell Transplantation. 4: 493-503. PMID 8520833 DOI: 10.1016/0963-6897(95)00041-U  0.426
1995 Clapp D, Freie B, Lee WH, Zhang YY. Molecular evidence that in situ-transduced fetal liver hematopoietic stem/progenitor cells give rise to medullary hematopoiesis in adult rats Blood. 86: 2113-2122. DOI: 10.1182/Blood.V86.6.2113.Bloodjournal8662113  0.398
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