Richard A. Manderville - Publications

Affiliations: 
University of Guelph (Canada), Guelph, Ontario, Canada 
Area:
Biochemistry

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gray MD, Deore PS, Chung AJ, Van Riesen AJ, Manderville RA, Prabhakar PS, Wetmore SD. Lighting Up the Thrombin-Binding Aptamer G-Quadruplex with an Internal Cyanine-Indole-Quinolinium Nucleobase Surrogate. Direct Fluorescent Intensity Readout for Thrombin Binding without Topology Switching. Bioconjugate Chemistry. PMID 33156614 DOI: 10.1021/acs.bioconjchem.0c00530  0.32
2019 Manning T, Al-Abdul-Wahid MS, Manderville RA, Josephy PD, Kung RW, Wetmore SD. Structure of an Unusual Tetracyclic Deoxyguanosine Adduct: Implications for Frameshift Mutagenicity by Ortho‒Cyano Nitroanilines. Chemical Research in Toxicology. PMID 31885260 DOI: 10.1021/acs.chemrestox.9b00411  0.32
2019 Kathuria P, Singh P, Sharma P, Manderville RA, Wetmore SD. Molecular Dynamics Study of One-Base Deletion Duplexes Containing the Major DNA Adduct Formed by Ochratoxin A: Effects of Sequence Context and Adduct Ionization State on Lesion Site Structure and Mutagenicity. The Journal of Physical Chemistry. B. PMID 31311268 DOI: 10.1021/acs.jpcb.9b06489  0.32
2019 Chung AJ, Deore PS, Al-Abdul-Wahid MS, Aboelnga M, Wetmore SD, Manderville RA. Acceptor Influence on Thiolate Sensing by Hemicyanine Dyes. The Journal of Organic Chemistry. PMID 30664354 DOI: 10.1021/acs.joc.9b00066  0.32
2018 Kathuria P, Sharma P, Manderville RA, Wetmore SD. Molecular dynamics simulations of mismatched DNA duplexes associated with the major C-linked 2'-deoxyguanosine adduct of the food mutagen ochratoxin A: Influence of opposing base, adduct ionization state and sequence on the structure of damaged DNA. Chemical Research in Toxicology. PMID 29924599 DOI: 10.1021/acs.chemrestox.8b00064  0.32
2018 Van Riesen AJ, Fadock KL, Deore PS, Desoky A, Manderville RA, Sowlati-Hashjin S, Wetmore SD. Manipulation of a DNA aptamer-protein binding site through arylation of internal guanine residues. Organic & Biomolecular Chemistry. PMID 29745412 DOI: 10.1039/c8ob00704g  0.32
2017 Berger FD, Sturla SJ, Kung RW, Montina T, Wetmore SD, Manderville RA. Conformational Preference and Fluorescence Response of a C-Linked C8-Biphenyl-Guanine Lesion in the NarI Mutational Hotspot: Evidence for Enhanced Syn Adduct Formation. Chemical Research in Toxicology. PMID 29186656 DOI: 10.1021/acs.chemrestox.7b00266  0.32
2017 Manderville RA, Wetmore SD. Mutagenicity of Ochratoxin A: Role for a Carbon-Linked C8-Deoxyguanosine Adduct? Journal of Agricultural and Food Chemistry. 65: 7097-7105. PMID 28830149 DOI: 10.1021/acs.jafc.6b03897  0.32
2017 Kathuria P, Sharma P, Manderville RA, Wetmore SD. Molecular Modeling of the Major DNA Adduct Formed from the Food Mutagen Ochratoxin A in NarI 2-base Deletion Duplexes: Impact of Sequence Context and Adduct Ionization on Conformational Preference and Mutagenicity. Chemical Research in Toxicology. PMID 28719194 DOI: 10.1021/acs.chemrestox.7b00103  0.32
2016 Manderville RA, Wetmore SD. C-Linked 8-aryl guanine nucleobase adducts: biological outcomes and utility as fluorescent probes. Chemical Science. 7: 3482-3493. PMID 29997840 DOI: 10.1039/c6sc00053c  0.32
2016 Manderville RA, Wetmore SD. Understanding the Mutagenicity of O-linked and C-linked Guanine DNA Adducts: A Combined Experimental and Computational Approach. Chemical Research in Toxicology. PMID 27768845 DOI: 10.1021/acs.chemrestox.6b00323  0.32
2016 Cservenyi TZ, Van Riesen AJ, Berger FD, Desoky A, Manderville RA. A Simple Molecular Rotor for Defining Nucleoside Environment within a DNA Aptamer-Protein Complex. Acs Chemical Biology. PMID 27447371 DOI: 10.1021/acschembio.6b00437  0.4
2016 Blanchard DJ, Manderville RA. An internal charge transfer-DNA platform for fluorescence sensing of divalent metal ions. Chemical Communications (Cambridge, England). PMID 27399260 DOI: 10.1039/c6cc04613d  0.4
2016 Fadock KL, Manderville RA, Sharma P, Wetmore SD. Optimization of fluorescent 8-heteroaryl-guanine probes for monitoring protein-mediated duplex → G-quadruplex exchange. Organic & Biomolecular Chemistry. PMID 27040462 DOI: 10.1039/c6ob00474a  0.4
2016 Manderville RA, Wetmore SD. C-Linked 8-Aryl guanine nucleobase adducts: Biological outcomes and utility as fluorescent probes Chemical Science. 7: 3482-3493. DOI: 10.1039/c6sc00053c  0.4
2016 Blanchard DJM, Fadock KL, Sproviero M, Deore PS, Cservenyi TZ, Manderville RA, Sharma P, Wetmore SD. Photophysical properties of push-pull 8-aryl-deoxyguanosine probes within duplex and G-quadruplex structures Journal of Materials Chemistry C. 4: 2915-2924. DOI: 10.1039/c5tc03354c  0.4
2015 Blanchard DJ, Cservenyi TZ, Manderville RA. Dual fluorescent deoxyguanosine mimics for FRET detection of G-quadruplex folding. Chemical Communications (Cambridge, England). 51: 16829-31. PMID 26435483 DOI: 10.1039/c5cc07154b  0.4
2015 Sproviero M, Verwey AM, Witham AA, Manderville RA, Sharma P, Wetmore SD. Enhancing Bulge Stabilization through Linear Extension of C8-Aryl-Guanine Adducts to Promote Polymerase Blockage or Strand Realignment to Produce a C:C Mismatch. Chemical Research in Toxicology. 28: 1647-58. PMID 26225720 DOI: 10.1021/acs.chemrestox.5b00233  0.32
2015 Witham AA, Verwey AM, Sproviero M, Manderville RA, Sharma P, Wetmore SD. Chlorine functionalization of a model phenolic C8-guanine adduct increases conformational rigidity and blocks extension by a Y-family DNA polymerase. Chemical Research in Toxicology. 28: 1346-56. PMID 26004422 DOI: 10.1021/acs.chemrestox.5b00143  0.4
2015 Sproviero M, Fadock KL, Witham AA, Manderville RA. Positional impact of fluorescently modified G-tetrads within polymorphic human telomeric G-quadruplex structures. Acs Chemical Biology. 10: 1311-8. PMID 25689465 DOI: 10.1021/cb5009926  0.4
2015 Sharma P, Majdi Yazdi M, Merriman A, Manderville RA, Wetmore SD. Influence of the linkage type and functional groups in the carcinogenic moiety on the conformational preferences of damaged DNA: structural and energetic characterization of carbon- and oxygen-linked C(8)-phenolic-guanine adducts. Chemical Research in Toxicology. 28: 782-96. PMID 25658653 DOI: 10.1021/tx500527p  0.4
2015 Witham AA, Sharma P, Wetmore SD, Gabryelski W, Manderville RA. Chlorine substitution promotes phenyl radical loss from C8-phenoxy-2'-deoxyguanosine adducts: implications for biomarker identification from chlorophenol exposure. Journal of Mass Spectrometry : Jms. 50: 81-7. PMID 25601678 DOI: 10.1002/jms.3475  0.4
2015 Sproviero M, Verwey AMR, Witham AA, Manderville RA, Sharma P, Wetmore SD. Enhancing Bulge Stabilization through Linear Extension of C8-Aryl-Guanine Adducts to Promote Polymerase Blockage or Strand Realignment to Produce a C:C Mismatch Chemical Research in Toxicology. 28: 1647-1658. DOI: 10.1021/acs.chemrestox.5b00233  0.4
2014 Sproviero M, Verwey AM, Rankin KM, Witham AA, Soldatov DV, Manderville RA, Fekry MI, Sturla SJ, Sharma P, Wetmore SD. Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity. Nucleic Acids Research. 42: 13405-21. PMID 25361967 DOI: 10.1093/nar/gku1093  0.4
2014 Sharma P, Manderville RA, Wetmore SD. Structural and energetic characterization of the major DNA adduct formed from the food mutagen ochratoxin A in the NarI hotspot sequence: influence of adduct ionization on the conformational preferences and implications for the NER propensity. Nucleic Acids Research. 42: 11831-45. PMID 25217592 DOI: 10.1093/nar/gku821  0.4
2014 Sproviero M, Manderville RA. Harnessing G-tetrad scaffolds within G-quadruplex forming aptamers for fluorescence detection strategies. Chemical Communications (Cambridge, England). 50: 3097-9. PMID 24513595 DOI: 10.1039/c3cc49560d  0.4
2014 Denyes JM, Krell PJ, Manderville RA, Ackermann HW, She YM, Kropinski AM. The genome and proteome of Serratia bacteriophage η which forms unstable lysogens. Virology Journal. 11: 6. PMID 24433577 DOI: 10.1186/1743-422X-11-6  0.4
2014 Sproviero M, Rankin KM, Witham AA, Manderville RA. Utility of 5'-O-2,7-dimethylpixyl for solid-phase synthesis of oligonucleotides containing acid-sensitive 8-aryl-guanine adducts. The Journal of Organic Chemistry. 79: 692-9. PMID 24392939 DOI: 10.1021/jo4024842  0.4
2014 Sproviero M, Fadock KL, Witham AA, Manderville RA, Sharma P, Wetmore SD. Electronic tuning of fluorescent 8-aryl-guanine probes for monitoring DNA duplex-quadruplex exchange Chemical Science. 5: 788-796. DOI: 10.1039/c3sc52625a  0.4
2013 Kuska MS, Witham AA, Sproviero M, Manderville RA, Majdi Yazdi M, Sharma P, Wetmore SD. Structural influence of C8-phenoxy-guanine in the NarI recognition DNA sequence. Chemical Research in Toxicology. 26: 1397-408. PMID 23984847 DOI: 10.1021/tx400252g  0.4
2013 Kuska MS, Majdi Yazdi M, Witham AA, Dahlmann HA, Sturla SJ, Wetmore SD, Manderville RA. Influence of chlorine substitution on the hydrolytic stability of biaryl ether nucleoside adducts produced by phenolic toxins. The Journal of Organic Chemistry. 78: 7176-85. PMID 23819526 DOI: 10.1021/jo401122j  0.4
2013 Sharma P, Manderville RA, Wetmore SD. Modeling the conformational preference of the carbon-bonded covalent adduct formed upon exposure of 2'-deoxyguanosine to ochratoxin A. Chemical Research in Toxicology. 26: 803-16. PMID 23560542 DOI: 10.1021/tx4000864  0.4
2012 Tozlovanu M, Canadas D, Pfohl-Leszkowicz A, Frenette C, Paugh RJ, Manderville RA. Glutathione conjugates of ochratoxin A as biomarkers of exposure. Arhiv Za Higijenu Rada I Toksikologiju. 63: 417-27. PMID 23334036 DOI: 10.2478/10004-1254-63-2012-2202  0.4
2012 Rankin KM, Sproviero M, Rankin K, Sharma P, Wetmore SD, Manderville RA. C8-heteroaryl-2'-deoxyguanosine adducts as conformational fluorescent probes in the NarI recognition sequence. The Journal of Organic Chemistry. 77: 10498-508. PMID 23171213 DOI: 10.1021/jo302164c  0.4
2012 Manderville RA, Omumi A, Rankin née Schlitt KM, Wilson KA, Millen AL, Wetmore SD. Fluorescent C-linked C8-aryl-guanine probe for distinguishing syn from anti structures in duplex DNA. Chemical Research in Toxicology. 25: 1271-82. PMID 22667322 DOI: 10.1021/tx300152q  0.4
2012 Omumi A, McLaughlin CK, Ben-Israel D, Manderville RA. Application of a fluorescent C-linked phenolic purine adduct for selective N7-metalation of DNA. The Journal of Physical Chemistry. B. 116: 6158-65. PMID 22607044 DOI: 10.1021/jp303138s  0.4
2012 Akman SA, Adams M, Case D, Park G, Manderville RA. Mutagenicity of ochratoxin A and its hydroquinone metabolite in the SupF gene of the mutation reporter plasmid Ps189. Toxins. 4: 267-80. PMID 22606376 DOI: 10.3390/toxins4040267  0.4
2012 Witham AA, Beach DG, Gabryelski W, Manderville RA. Hydroxyl radical-induced oxidation of a phenolic C-linked 2'-deoxyguanosine adduct yields a reactive catechol. Chemical Research in Toxicology. 25: 315-25. PMID 22176608 DOI: 10.1021/tx200365r  0.4
2012 Hadjeba-Medjdoub K, Tozlovanu M, Pfohl-Leszkowicz A, Frenette C, Paugh RJ, Manderville RA. Structure-activity relationships imply different mechanisms of action for ochratoxin A-mediated cytotoxicity and genotoxicity. Chemical Research in Toxicology. 25: 181-90. PMID 22126095 DOI: 10.1021/tx200406c  0.4
2012 Pfohl-Leszkowicz A, Manderville RA. An update on direct genotoxicity as a molecular mechanism of ochratoxin a carcinogenicity. Chemical Research in Toxicology. 25: 252-62. PMID 22054007 DOI: 10.1021/tx200430f  0.4
2011 Millen AL, Kamenz BL, Leavens FM, Manderville RA, Wetmore SD. Conformational flexibility of C8-phenoxylguanine adducts in deoxydinucleoside monophosphates. The Journal of Physical Chemistry. B. 115: 12993-3002. PMID 21942470 DOI: 10.1021/jp2057332  0.4
2011 Omumi A, Millen AL, Wetmore SD, Manderville RA. Fluorescent properties and conformational preferences of C-linked phenolic-DNA adducts. Chemical Research in Toxicology. 24: 1694-709. PMID 21905681 DOI: 10.1021/tx200247f  0.4
2011 Schlitt KM, Millen AL, Wetmore SD, Manderville RA. An indole-linked C8-deoxyguanosine nucleoside acts as a fluorescent reporter of Watson-Crick versus Hoogsteen base pairing. Organic & Biomolecular Chemistry. 9: 1565-71. PMID 21240404 DOI: 10.1039/c0ob00883d  0.4
2011 Sagoo S, Beach DG, Manderville RA, Gabryelski W. Tautomerization in gas-phase ion chemistry of isomeric C-8 deoxyguanosine adducts from phenol-induced DNA damage. Journal of Mass Spectrometry : Jms. 46: 41-9. PMID 21184435 DOI: 10.1002/jms.1869  0.4
2011 Omumi A, Beach DG, Baker M, Gabryelski W, Manderville RA. Postsynthetic guanine arylation of DNA by Suzuki-Miyaura cross-coupling. Journal of the American Chemical Society. 133: 42-50. PMID 21067186 DOI: 10.1021/ja106158b  0.4
2010 Millen AL, Churchill CD, Manderville RA, Wetmore SD. Effect of Watson-Crick and Hoogsteen base pairing on the conformational stability of C8-phenoxyl-2'-deoxyguanosine adducts. The Journal of Physical Chemistry. B. 114: 12995-3004. PMID 20853889 DOI: 10.1021/jp105817p  0.4
2010 Jennings-Gee JE, Tozlovanu M, Manderville R, Miller MS, Pfohl-Leszkowicz A, Schwartz GG. Ochratoxin A: in utero exposure in mice induces adducts in testicular DNA. Toxins. 2: 1428-44. PMID 20648226 DOI: 10.3390/toxins2061428  0.4
2010 Millen AL, Manderville RA, Wetmore SD. Conformational flexibility of c8-phenoxyl-2'-deoxyguanosine nucleotide adducts. The Journal of Physical Chemistry. B. 114: 4373-82. PMID 20201579 DOI: 10.1021/jp911993f  0.4
2010 Mantle PG, Faucet-Marquis V, Manderville RA, Squillaci B, Pfohl-Leszkowicz A. Structures of covalent adducts between DNA and ochratoxin a: a new factor in debate about genotoxicity and human risk assessment. Chemical Research in Toxicology. 23: 89-98. PMID 19928877 DOI: 10.1021/tx900295a  0.4
2010 Schwartz GG, Manderville RA, Pfohl-Leszkowicz A. Response to comments of Peter G. Mantle Toxins. 2: 2337-2339. DOI: 10.3390/toxins2102337  0.4
2009 Schlitt KM, Sun KW, Paugh RJ, Millen AL, Navarro-Whyte L, Wetmore SD, Manderville RA. Concerning the hydrolytic stability of 8-aryl-2'-deoxyguanosine nucleoside adducts: implications for abasic site formation at physiological pH. The Journal of Organic Chemistry. 74: 5793-802. PMID 19603821 DOI: 10.1021/jo901080w  0.4
2009 Pfohl-Leszkowicz A, Gabryelski W, Manderville RA. Formation of 2'-deoxyguanosine-carbon 8-bound ochratoxin A adduct in rat kidney DNA. Molecular Nutrition & Food Research. 53: 154-5; author reply . PMID 19123177 DOI: 10.1002/mnfr.200890049  0.4
2009 Manderville RA, Kropinski AM. Approaches to the compositional analysis of DNA. Methods in Molecular Biology (Clifton, N.J.). 502: 11-7. PMID 19082548 DOI: 10.1007/978-1-60327-565-1_2  0.4
2009 Manderville RA. Structural and biological impact of radical addition reactions with DNA nucleobases Advances in Physical Organic Chemistry. 43: 177-218. DOI: 10.1016/S0065-3160(08)00005-1  0.4
2009 Manderville RA. DNA Damage by Phenoxyl Radicals Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. 421-443. DOI: 10.1002/9780470526279.ch14  0.4
2008 Weishar JL, McLaughlin CK, Baker M, Gabryelski W, Manderville RA. Oxidation of a biomarker for phenol carcinogen exposure: expanding the redox chemistry of 2'-deoxyguanosine. Organic Letters. 10: 1839-42. PMID 18393513 DOI: 10.1021/ol8004694  0.4
2008 Millen AL, McLaughlin CK, Sun KM, Manderville RA, Wetmore SD. Computational and experimental evidence for the structural preference of phenolic C-8 purine adducts Journal of Physical Chemistry A. 112: 3742-3753. PMID 18376879 DOI: 10.1021/jp712058a  0.4
2008 Pfohl-Leszkowicz A, Molinié A, Tozlovanu M, Manderville RA. Combined toxic effects of ochratoxin a and citrinin, in vivo and in vitro Acs Symposium Series. 1001: 56-79. DOI: 10.1021/bk-2008-1001.ch003  0.4
2007 La JQ, Michaelides AA, Manderville RA. Tautomeric equilibria in phenolic A-ring derivatives of prodigiosin natural products. The Journal of Physical Chemistry. B. 111: 11803-11. PMID 17867672 DOI: 10.1021/jp074620z  0.4
2007 Sun KM, McLaughlin CK, Lantero DR, Manderville RA. Biomarkers for phenol carcinogen exposure act as pH-sensing fluorescent probes Journal of the American Chemical Society. 129: 1894-1895. PMID 17256942 DOI: 10.1021/ja068416l  0.4
2007 Pfohl-Leszkowicz A, Manderville RA. Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans. Molecular Nutrition & Food Research. 51: 61-99. PMID 17195275 DOI: 10.1002/mnfr.200600137  0.4
2007 Park G, Tomlinson JT, Misenheimer JA, Kucera GL, Manderville RA. Photo-induced cytotoxicity of prodigiosin analogues Bulletin of the Korean Chemical Society. 28: 49-52.  0.4
2006 Tomlinson JT, Park G, Misenheimer JA, Kucera GL, Hesp K, Manderville RA. Photoinduced cytotoxicity and thioadduct formation by a prodigiosin analogue. Organic Letters. 8: 4951-4. PMID 17020344 DOI: 10.1021/ol061998r  0.4
2006 Tozlovanu M, Faucet-Marquis V, Pfohl-Leszkowicz A, Manderville RA. Genotoxicity of the hydroquinone metabolite of ochratoxin A: structure-activity relationships for covalent DNA adduction. Chemical Research in Toxicology. 19: 1241-7. PMID 16978030 DOI: 10.1021/tx060138g  0.4
2006 McLaughlin CK, Lantero DR, Manderville RA. Conformational properties of a phototautomerizable nucleoside biomarker for phenolic carcinogen exposure Journal of Physical Chemistry A. 110: 6224-6230. PMID 16686455 DOI: 10.1021/jp0617571  0.4
2006 Manderville RA, Pfohl-Leszkowicz A. Chapter 4 Genotoxicity of Chlorophenols and Ochratoxin A Advances in Molecular Toxicology. 1: 85-138. DOI: 10.1016/S1872-0854(06)01004-6  0.4
2005 Manderville RA. A case for the genotoxicity of ochratoxin A by bioactivation and covalent DNA adduction. Chemical Research in Toxicology. 18: 1091-7. PMID 16022501 DOI: 10.1021/tx050070p  0.4
2005 Xu M, Nelson GB, Moore JE, McCoy TP, Dai J, Manderville RA, Ross JA, Miller MS. Induction of Cyp1a1 and Cyp1b1 and formation of DNA adducts in C57BL/6, Balb/c, and F1 mice following in utero exposure to 3-methylcholanthrene. Toxicology and Applied Pharmacology. 209: 28-38. PMID 15885734 DOI: 10.1016/j.taap.2005.03.012  0.4
2005 Dai J, Sloat AL, Wright MW, Manderville RA. Role of phenoxyl radicals in DNA adduction by chlorophenol xenobiotics following peroxidase activation. Chemical Research in Toxicology. 18: 771-9. PMID 15833038 DOI: 10.1021/tx0500023  0.4
2005 Manderville RA. Ambident reactivity of phenoxyl radicals in DNA adduction Canadian Journal of Chemistry. 83: 1261-1267. DOI: 10.1139/v05-121  0.4
2004 Dai J, Park G, Perry JL, Il'ichev YV, Bow DA, Pritchard JB, Faucet V, Pfohl-Leszkowicz A, Manderville RA, Simon JD. Molecular aspects of the transport and toxicity of ochratoxin a. Accounts of Chemical Research. 37: 874-81. PMID 15612677 DOI: 10.1021/ar0302134  0.4
2004 Faucet V, Pfohl-Leszkowicz A, Dai J, Castegnaro M, Manderville RA. Evidence for covalent DNA adduction by ochratoxin A following chronic exposure to rat and subacute exposure to pig. Chemical Research in Toxicology. 17: 1289-96. PMID 15377164 DOI: 10.1021/tx049877s  0.4
2003 Dai J, Wright MW, Manderville RA. An oxygen-bonded c8-deoxyguanosine nucleoside adduct of pentachlorophenol by peroxidase activation: evidence for ambident c8 reactivity by phenoxyl radicals. Chemical Research in Toxicology. 16: 817-21. PMID 12870883 DOI: 10.1021/tx034084b  0.4
2003 Manderville RA, Wade Calcutt M, Dai J, Park G, Gillman IG, Noftle RE, Mohammed AK, Birincioglu M, Dizdaroglu M, Rodriguez H, Akman SA. Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A. Journal of Inorganic Biochemistry. 95: 87-96. PMID 12763652 DOI: 10.1016/S0162-0134(03)00104-1  0.4
2003 Buncel E, Park KT, Dust JM, Manderville RA. Concerning the denticity of the dimethylsulfinyl anion in Meisenheimer complexation. Journal of the American Chemical Society. 125: 5388-92. PMID 12720452 DOI: 10.1021/ja0298489  0.4
2003 Dai J, Wright MW, Manderville RA. Ochratoxin a forms a carbon-bonded c8-deoxyguanosine nucleoside adduct: implications for c8 reactivity by a phenolic radical. Journal of the American Chemical Society. 125: 3716-7. PMID 12656599 DOI: 10.1021/ja034221r  0.4
2003 Park G, Tomlinson JT, Melvin MS, Wright MW, Day CS, Manderville RA. Zinc and copper complexes of prodigiosin: implications for copper-mediated double-strand DNA cleavage. Organic Letters. 5: 113-6. PMID 12529118 DOI: 10.1021/ol027165s  0.4
2003 Buncel E, Dust JM, Manderville RA, Tarkka RM. Regioselectivity of Meisenheimer complexation in reaction of oxygen-centred nucleophiles with picryl aryl ethers: Polar vs. SET mechanisms Canadian Journal of Chemistry. 81: 443-456. DOI: 10.1139/v03-014  0.4
2003 Perry JL, Il'ichev YV, Kempf VR, McClendon J, Park G, Manderville RA, Rüker F, Dockal M, Simon JD. Binding of ochratoxin a derivatives to human serum albumin Journal of Physical Chemistry B. 107: 6644-6647.  0.4
2002 Brow ME, Dai J, Park G, Wright MW, Gillman IG, Manderville RA. Photochemically catalyzed reaction of ochratoxin A with D- and L-cysteine. Photochemistry and Photobiology. 76: 649-56. PMID 12511045 DOI: 10.1562/0031-8655(2002)076<0649:PCROOA>2.0.CO;2  0.4
2002 Dai J, Park G, Wright MW, Adams M, Akman SA, Manderville RA. Detection and characterization of a glutathione conjugate of ochratoxin A. Chemical Research in Toxicology. 15: 1581-8. PMID 12482240 DOI: 10.1021/tx0255929  0.4
2002 Melvin MS, Calcutt MW, Noftle RE, Manderville RA. Influence of the a-ring on the redox and nuclease properties of the prodigiosins: importance of the bipyrrole moiety in oxidative DNA cleavage. Chemical Research in Toxicology. 15: 742-8. PMID 12018997 DOI: 10.1021/tx025508p  0.4
2002 Melvin MS, Tomlinson JT, Park G, Day CS, Saluta GR, Kucera GL, Manderville RA. Influence of the a-ring on the proton affinity and anticancer properties of the prodigiosins. Chemical Research in Toxicology. 15: 734-41. PMID 12018996 DOI: 10.1021/tx025507x  0.4
2001 Manderville RA. Synthesis, proton-affinity and anti-cancer properties of the prodigiosin-group natural products Current Medicinal Chemistry. Anti-Cancer Agents. 1: 195-218. PMID 12678767  0.4
2001 Melvin MS, Wooton KE, Rich CC, Saluta GR, Kucera GL, Lindquist N, Manderville RA. Copper-nuclease efficiency correlates with cytotoxicity for the 4-methoxypyrrolic natural products. Journal of Inorganic Biochemistry. 87: 129-35. PMID 11730894 DOI: 10.1016/S0162-0134(01)00338-5  0.4
2001 Calcutt MW, Gillman IG, Noftle RE, Manderville RA. Electrochemical oxidation of ochratoxin A: correlation with 4-chlorophenol. Chemical Research in Toxicology. 14: 1266-72. PMID 11559042 DOI: 10.1021/tx015516q  0.4
2001 Keck MV, Manderville RA, Hecht SM. Chemical and structural characterization of the interaction of bleomycin A2 with d(CGCGAATTCGCG)2. efficient, double-strand DNA cleavage accessible without structural reorganization. Journal of the American Chemical Society. 123: 8690-700. PMID 11535073 DOI: 10.1021/ja003795i  0.4
2001 Il'ichev YV, Perry JL, Manderville RA, Chignell CF, Simon JD. The pH-dependent primary photoreactions of ochratoxin A Journal of Physical Chemistry B. 105: 11369-11376. DOI: 10.1021/jp012683q  0.4
2000 Melvin MS, Tomlinson JT, Saluta GR, Kucera GL, Lindquist N, Manderville RA. Double-strand DNA cleavage by copper·prodigiosin [24] Journal of the American Chemical Society. 122: 6333-6334. DOI: 10.1021/ja0000798  0.4
1999 Melvin MS, Ferguson DC, Lindquist N, Manderville RA. DNA Binding by 4-Methoxypyrrolic Natural Products. Preference for Intercalation at AT Sites by Tambjamine E and Prodigiosin. The Journal of Organic Chemistry. 64: 6861-6869. PMID 11674696 DOI: 10.1021/jo990944a  0.4
1999 Gillman IG, Clark TN, Manderville RA. Oxidation of ochratoxin A by an Fe-porphyrin system: model for enzymatic activation and DNA cleavage. Chemical Research in Toxicology. 12: 1066-76. PMID 10563832 DOI: 10.1021/tx9901074  0.4
1998 Borah S, Melvin MS, Lindquist N, Manderville RA. Copper-mediated nuclease activity of a tambjamine alkaloid Journal of the American Chemical Society. 120: 4557-4562. DOI: 10.1021/ja9729746  0.4
1998 Gillman IG, Day CS, Manderville RA. Stepwise Formation of a Nonsymmetric Dinuclear Copper Complex of Ochratoxin A Inorganic Chemistry. 37: 6385-6388.  0.4
1998 Gillman IG, Yezek JM, Manderville RA. Ochratoxin A acts as a photoactivatable DNA cleaving agent Chemical Communications. 647-648.  0.4
1998 Dust JM, Manderville RA. Carbon versus oxygen nucleophilic selectivity in the reaction of the aryloxide ions, 2,6- and 3,5-di-tert-butylphenoxide, with the 2- [(nitro)(x)aryl]-4,6-dinitrobenzotriazole 1-oxide series of super- electrophiles. Stereoelectronic factors on C-7 Meisenheimer complex formation versus C-1' S(N)Ar displacement Canadian Journal of Chemistry. 76: 662-671.  0.4
1998 Ardus JA, Gillman IG, Manderville RA. On the role of copper and iron in DNA cleavage by ochratoxin A. Structure-activity relationships in metal binding and copper-mediated DNA cleavage Canadian Journal of Chemistry. 76: 907-918.  0.4
1997 Manderville RA, Buncel E. An Unexpected Ring Protonation in Meisenheimer Complex Formation Journal of Organic Chemistry. 62: 7614-7620.  0.4
1997 Buncel E, Manderville RA, Dust JM. Ambident reactivity of aryloxide ions towards the super-electrophile, 4,6-dinitrobenzofuroxan, Kinetics, thermodynamics and stereoelectronic factors on regioselectivity Journal of the Chemical Society. Perkin Transactions 2. 1019-1026.  0.4
1996 Buncel E, Dust JM, Manderville RA. Ambident reactivity of enolate ions toward 1,3,5-trinitrobenzene. The first observation of an oxygen-bonded enolate Meisenheimer complex Journal of the American Chemical Society. 118: 6072-6073. DOI: 10.1021/ja960590u  0.4
1996 Manderville RA, Dust JM, Buncel E. Reaction pathways for ambident aryloxide O- and C-nucleophiles in SNAr displacement versus Meisenheimer complex formation with picryl halides. Stereoelectronic effects on regioselectivity Journal of Physical Organic Chemistry. 9: 515-528.  0.4
1996 Keum SR, Kazmaier PM, Cheon KS, Manderville RA, Buncel E. The structural identification of dicondensed products derived from the reaction of excess Fischer's base with salicylaldehydes Bulletin of the Korean Chemical Society. 17: 391-393.  0.4
1995 Manderville RA, Ellena JF, Hecht SM. Interaction of Zn(II)·Bleomycin with d(CGCTAGCG)2. A binding model based on NMR experiments and restrained molecular dynamics calculations Journal of the American Chemical Society. 117: 7891-7903. DOI: 10.1021/ja00135a007  0.4
1994 Manderville RA, Ellena JF, Hecht SM. Solution structure of a Zn(II)·bleomycin A5-d(CGCTAGCG)2 complex Journal of the American Chemical Society. 116: 10851-10852. DOI: 10.1021/ja00102a087  0.4
1993 Buncel E, Manderville RA. Ambident reactivity of aryloxide ions towards 1,3,5‐trinitrobenzene, low‐temperature characterization of the elusive Oxygen‐bonded σ‐complexes by 1H and 13C NMR spectroscopy Journal of Physical Organic Chemistry. 6: 71-82. DOI: 10.1002/poc.610060202  0.4
1993 Manderville RA, Buncel E. Regioselectivity and stereoelectronic factors in the reactions of aryloxide nucleophiles with 4-nitrobenzofuroxan Journal of the Chemical Society, Perkin Transactions 2. 1887-1894.  0.4
1993 Manderville RA, Buncel E. Inversion of kinetic and thermodynamic preferences in meisenheimer complex formation: Regioselectivity in the reaction of 2,4,6-trimethylphenoxide ion with 2,4,6-trinitroanisole and the importance of stereoelectronic factors Journal of the American Chemical Society. 115: 8985-8989.  0.4
1992 Keum S‐, Lee K‐, Kazmaier PM, Manderville RA, Buncel E. Thermo‐ and photochromic dyes: Spiro(indolinebenzopyrans). 2—detailed assignment of the 1H NMR spectra and structural aspects of the closed form of 1,3,3‐trimethylspiro(indoline‐2,2′‐benzopyrans) Magnetic Resonance in Chemistry. 30: 1128-1131. DOI: 10.1002/mrc.1260301119  0.4
1992 Buncel E, Dust JM, Joñczyk A, Manderville RA, Onyido I. Regioselectivity in the reaction of ambident phenoxide ion and methoxide and hydroxide ions with 2,4,6-trinitroanisole. Kinetic and thermodynamic control Journal of the American Chemical Society. 114: 5610-5619.  0.4
Show low-probability matches.