Douglas H. Sweet - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology, Pharmacology, Pharmaceutical Chemistry

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Uddin ME, Eisenmann ED, Li Y, Huang KM, Garrison DA, Talebi Z, Gibson AA, Jin Y, Nepal M, Bonilla IM, Fu Q, Sun X, Millar A, Tarasov M, Jay CE, ... ... Sweet DH, et al. MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia. International Journal of Molecular Sciences. 23. PMID 35955741 DOI: 10.3390/ijms23158607  0.36
2021 Sweet DH. Organic Cation Transporter Expression and Function in the CNS. Handbook of Experimental Pharmacology. PMID 33963461 DOI: 10.1007/164_2021_463  0.474
2019 Luo SS, Yu CP, Hsieh YW, Chao PL, Sweet DH, Hou YC, Lin SP. Effects of antibiotics on the pharmacokinetics of indoxyl sulfate, a nephro-cardiovascular toxin. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-20. PMID 31448977 DOI: 10.1080/00498254.2019.1660433  0.516
2018 Lai RE, Jay CE, Sweet DH. Organic solute carrier 22 (SLC22) family: Potential for interactions with food, herbal/dietary supplements, endogenous compounds, and drugs. Journal of Food and Drug Analysis. 26: S45-S60. PMID 29703386 DOI: 10.1016/J.Jfda.2018.03.002  0.399
2017 Pan X, Iyer KA, Liu H, Sweet DH, Dukat M. A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). Bioorganic & Medicinal Chemistry Letters. PMID 28811134 DOI: 10.1016/J.Bmcl.2017.08.008  0.505
2017 Römermann K, Fedrowitz M, Hampel P, Kaczmarek E, Töllner K, Erker T, Sweet DH, Löscher W. Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain. Neuropharmacology. PMID 28192112 DOI: 10.1016/J.Neuropharm.2017.02.006  0.452
2017 Yu CP, Sweet DH, Peng YH, Hsieh YW, Chao PL, Hou YC, Lin SP. Effects of nonsteroidal anti-inflammatory drugs on the renal excretion of indoxyl sulfate, a nephro-cardiovascular toxin, in rats. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 101: 66-70. PMID 28185988 DOI: 10.1016/J.Ejps.2017.02.007  0.442
2015 Peng YH, Sweet DH, Lin SP, Yu CP, Lee Chao PD, Hou YC. Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure. Scientific Reports. 5: 16226. PMID 26552961 DOI: 10.1038/Srep16226  0.428
2015 Foti RS, Tyndale RF, Garcia KL, Sweet DH, Nagar S, Sharan S, Rock DA. "Target-Site" Drug Metabolism and Transport. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1156-68. PMID 25986849 DOI: 10.1124/Dmd.115.064576  0.41
2014 Wang L, Venitz J, Sweet DH. Cumulative organic anion transporter-mediated drug-drug interaction potential of multiple components in salvia miltiorrhiza (danshen) preparations. Pharmaceutical Research. 31: 3503-14. PMID 24962510 DOI: 10.1007/S11095-014-1437-9  0.465
2014 Masereeuw R, Mutsaers HA, Toyohara T, Abe T, Jhawar S, Sweet DH, Lowenstein J. The kidney and uremic toxin removal: glomerulus or tubule? Seminars in Nephrology. 34: 191-208. PMID 24780473 DOI: 10.1016/J.Semnephrol.2014.02.010  0.511
2014 Pan X, Wang L, Gründemann D, Sweet DH. Inhibition of human organic cation transporters by the alkaloids matrine and oxymatrine. Fitoterapia. 92: 206-10. PMID 24291757 DOI: 10.1016/J.Fitote.2013.11.009  0.558
2014 Farthing CA, Sweet DH. Expression and function of organic cation and anion transporters (SLC22 family) in the CNS. Current Pharmaceutical Design. 20: 1472-86. PMID 23789957 DOI: 10.2174/13816128113199990456  0.542
2013 Wang L, Halquist MS, Sweet DH. Simultaneous determination of gallic acid and gentisic acid in organic anion transporter expressing cells by liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 937: 91-6. PMID 24022056 DOI: 10.1016/J.Jchromb.2013.08.024  0.338
2013 Wang L, Pan X, Sweet DH. The anthraquinone drug rhein potently interferes with organic anion transporter-mediated renal elimination. Biochemical Pharmacology. 86: 991-6. PMID 23973525 DOI: 10.1016/J.Bcp.2013.08.016  0.516
2013 Pan X, Wang L, Gründemann D, Sweet DH. Interaction of Ethambutol with human organic cation transporters of the SLC22 family indicates potential for drug-drug interactions during antituberculosis therapy. Antimicrobial Agents and Chemotherapy. 57: 5053-9. PMID 23917312 DOI: 10.1128/Aac.01255-13  0.476
2013 Wang L, Sweet DH. Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11). Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 612527. PMID 23573138 DOI: 10.1155/2013/612527  0.434
2013 Mulgaonkar A, Venitz J, Gründemann D, Sweet DH. Human organic cation transporters 1 (SLC22A1), 2 (SLC22A2), and 3 (SLC22A3) as disposition pathways for fluoroquinolone antimicrobials. Antimicrobial Agents and Chemotherapy. 57: 2705-11. PMID 23545524 DOI: 10.1128/Aac.02289-12  0.51
2013 Breljak D, Brzica H, Sweet DH, Anzai N, Sabolic I. Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys. American Journal of Physiology. Renal Physiology. 304: F1114-26. PMID 23389457 DOI: 10.1152/Ajprenal.00201.2012  0.43
2013 Wang L, Sweet DH. Competitive inhibition of human organic anion transporters 1 (SLC22A6), 3 (SLC22A8) and 4 (SLC22A11) by major components of the medicinal herb Salvia miltiorrhiza (Danshen). Drug Metabolism and Pharmacokinetics. 28: 220-8. PMID 23229784 DOI: 10.2133/Dmpk.Dmpk-12-Rg-116  0.392
2013 Wang L, Sweet DH. Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease. The Aaps Journal. 15: 53-69. PMID 23054972 DOI: 10.1208/S12248-012-9413-Y  0.552
2012 Wang L, Sweet DH. Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11). Biochemical Pharmacology. 84: 1088-95. PMID 22877817 DOI: 10.1016/J.Bcp.2012.07.027  0.415
2012 Wang L, Sweet DH. Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8). Evidence-Based Complementary and Alternative Medicine : Ecam. 2012: 872458. PMID 22844339 DOI: 10.1155/2012/872458  0.509
2012 Mulgaonkar A, Venitz J, Sweet DH. Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters. Expert Opinion On Drug Metabolism & Toxicology. 8: 553-69. PMID 22435536 DOI: 10.1517/17425255.2012.674512  0.45
2011 Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BØ, Nigam SK. Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis. The Journal of Biological Chemistry. 286: 31522-31. PMID 21757732 DOI: 10.1074/Jbc.M111.272534  0.434
2011 Dickman KG, Sweet DH, Bonala R, Ray T, Wu A. Physiological and molecular characterization of aristolochic acid transport by the kidney. The Journal of Pharmacology and Experimental Therapeutics. 338: 588-97. PMID 21546538 DOI: 10.1124/Jpet.111.180984  0.603
2010 Schnabolk GW, Gupta B, Mulgaonkar A, Kulkarni M, Sweet DH. Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles. The Journal of Pharmacology and Experimental Therapeutics. 334: 927-35. PMID 20519554 DOI: 10.1124/Jpet.110.168765  0.765
2010 VanWert AL, Gionfriddo MR, Sweet DH. Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology. Biopharmaceutics & Drug Disposition. 31: 1-71. PMID 19953504 DOI: 10.1002/Bdd.693  0.732
2009 Barros SA, Srimaroeng C, Perry JL, Walden R, Dembla-Rajpal N, Sweet DH, Pritchard JB. Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport. The Journal of Biological Chemistry. 284: 2672-9. PMID 19028678 DOI: 10.1074/Jbc.M808078200  0.514
2008 Vanwert AL, Srimaroeng C, Sweet DH. Organic anion transporter 3 (oat3/slc22a8) interacts with carboxyfluoroquinolones, and deletion increases systemic exposure to ciprofloxacin. Molecular Pharmacology. 74: 122-31. PMID 18381565 DOI: 10.1124/Mol.107.042853  0.739
2008 VanWert AL, Sweet DH. Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates. Pharmaceutical Research. 25: 453-62. PMID 17660957 DOI: 10.1007/S11095-007-9407-0  0.764
2007 Vanwert AL, Bailey RM, Sweet DH. Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G. American Journal of Physiology. Renal Physiology. 293: F1332-41. PMID 17686950 DOI: 10.1152/Ajprenal.00319.2007  0.737
2007 Sweet DH. Kinase signaling pathways regulate fine tuning of transporter activity. American Journal of Physiology. Renal Physiology. 293: F20. PMID 17409280 DOI: 10.1152/Ajprenal.00126.2007  0.432
2006 Whitley AC, Sweet DH, Walle T. Site-specific accumulation of the cancer preventive dietary polyphenol ellagic acid in epithelial cells of the aerodigestive tract. The Journal of Pharmacy and Pharmacology. 58: 1201-9. PMID 16945178 DOI: 10.1211/Jpp.58.9.0006  0.517
2006 Sweet DH, Eraly SA, Vaughn DA, Bush KT, Nigam SK. Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney International. 69: 837-45. PMID 16518343 DOI: 10.1038/Sj.Ki.5000170  0.518
2006 Schnabolk GW, Youngblood GL, Sweet DH. Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). American Journal of Physiology. Renal Physiology. 291: F314-21. PMID 16478971 DOI: 10.1152/Ajprenal.00497.2005  0.761
2005 Whitley AC, Sweet DH, Walle T. The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1097-100. PMID 15870380 DOI: 10.1124/Dmd.105.004275  0.509
2005 Sweet DH. Organic anion transporter (Slc22a) family members as mediators of toxicity. Toxicology and Applied Pharmacology. 204: 198-215. PMID 15845414 DOI: 10.1016/J.Taap.2004.10.016  0.556
2004 Sykes D, Sweet DH, Lowes S, Nigam SK, Pritchard JB, Miller DS. Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. American Journal of Physiology. Renal Physiology. 286: F972-8. PMID 15075193 DOI: 10.1152/Ajprenal.00356.2003  0.599
2004 Youngblood GL, Sweet DH. Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. American Journal of Physiology. Renal Physiology. 287: F236-44. PMID 15068970 DOI: 10.1152/Ajprenal.00012.2004  0.585
2003 Aslamkhan A, Han YH, Walden R, Sweet DH, Pritchard JB. Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells. American Journal of Physiology. Renal Physiology. 285: F775-83. PMID 12837685 DOI: 10.1152/Ajprenal.00140.2003  0.523
2003 Sweet DH, Chan LM, Walden R, Yang XP, Miller DS, Pritchard JB. Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient. American Journal of Physiology. Renal Physiology. 284: F763-9. PMID 12488248 DOI: 10.1152/Ajprenal.00405.2002  0.506
2002 Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. The Journal of Biological Chemistry. 277: 26934-43. PMID 12011098 DOI: 10.1074/Jbc.M203803200  0.594
2001 Pombrio JM, Giangreco A, Li L, Wempe MF, Anders MW, Sweet DH, Pritchard JB, Ballatori N. Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1 Molecular Pharmacology. 60: 1091-1099. PMID 11641438 DOI: 10.1124/Mol.60.5.1091  0.511
2001 Sweet DH, Miller DS, Pritchard JB. Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus. The Journal of Biological Chemistry. 276: 41611-9. PMID 11553644 DOI: 10.1074/Jbc.M108472200  0.525
2001 Sweet DH, Bush KT, Nigam SK. The organic anion transporter family: From physiology to ontogeny and the clinic American Journal of Physiology - Renal Physiology. 281: F197-F205. PMID 11457711 DOI: 10.1152/Ajprenal.2001.281.2.F197  0.54
2001 Han YH, Sweet DH, Hu DN, Pritchard JB. Characterization of a novel cationic drug transporter in human retinal pigment epithelial cells Journal of Pharmacology and Experimental Therapeutics. 296: 450-457. PMID 11160630  0.483
2000 Sweet DH, Miller DS, Pritchard JB. Basolateral localization of organic cation transporter 2 in intact renal proximal tubules. American Journal of Physiology. Renal Physiology. 279: F826-34. PMID 11053042 DOI: 10.1152/Ajprenal.2000.279.5.F826  0.396
1999 Sweet DH, Miller DS, Pritchard JB. Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules. American Journal of Physiology. Renal Physiology. 276: F864-F873. PMID 29591377 DOI: 10.1152/ajprenal.1999.276.6.F864  0.377
1999 Sweet DH, Pritchard JB. rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger American Journal of Physiology - Renal Physiology. 277. PMID 10600936 DOI: 10.1152/Ajprenal.1999.277.6.F890  0.505
1999 Pritchard JB, Sweet DH, Miller DS, Walden R. Mechanism of organic anion transport across the apical membrane of choroid plexus. The Journal of Biological Chemistry. 274: 33382-7. PMID 10559217 DOI: 10.1074/Jbc.274.47.33382  0.48
1999 Sweet DH, Pritchard JB. The molecular biology of renal organic anion and organic cation transporters Cell Biochemistry and Biophysics. 31: 89-118. PMID 10505670 DOI: 10.1007/Bf02738157  0.508
1999 Cihlar T, Lin DC, Pritchard JB, Fuller MD, Mendel DB, Sweet DH. The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1. Molecular Pharmacology. 56: 570-80. PMID 10462545 DOI: 10.1124/Mol.56.3.570  0.524
1999 Sweet DH, Miller DS, Pritchard JB. Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules. The American Journal of Physiology. 276: F864-73. PMID 10362775 DOI: 10.1152/Ajprenal.1999.276.6.F864  0.473
1999 Pan BF, Sweet DH, Pritchard JB, Chen R, Nelson JA. A transfected cell model for the renal toxin transporter, rOCT2 Toxicological Sciences. 47: 181-186. PMID 10220855 DOI: 10.1093/toxsci/47.2.181  0.477
1997 Sweet DH, Wolff NA, Pritchard JB. Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney Journal of Biological Chemistry. 272: 30088-30095. PMID 9374486 DOI: 10.1074/Jbc.272.48.30088  0.566
1997 Sweet DH, Wolff NA, Pritchard JB. Expression cloning and characterization of a novel organic anion transporter from rat kidney Faseb Journal. 11.  0.511
1997 Pritchard JB, Walsh RC, Sweet DH. Characterization of organic cation transporter 2 (OCT2) isolated from rat kidney Faseb Journal. 11.  0.463
1996 Walsh RC, Sweet DH, Hall LA, Pritchard JB. Expression cloning and characterization of a novel organic cation transporter from rat kidney Faseb Journal. 10.  0.52
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