| Year |
Citation |
Score |
| 2020 |
Kovacs SJ, Ting L, Praestgaard J, Sunkara G, Sun H, Stein DS, Tanaka SK, Villano S. An Open-Label Study of the Impact of Hepatic Impairment on the Pharmacokinetics and Safety of Single Oral and Intravenous Doses of Omadacycline. Antimicrobial Agents and Chemotherapy. PMID 32839218 DOI: 10.1128/Aac.01650-20 |
0.366 |
|
| 2018 |
Schuehly U, Ayalasomayajula S, Buchbjerg J, Pal P, Golor G, Prescott MF, Sunkara G, Hinder M, Langenickel TH. Pharmacodynamic interaction between intravenous nitroglycerin and oral sacubitril/valsartan (LCZ696) in healthy subjects. European Journal of Clinical Pharmacology. PMID 29974143 DOI: 10.1007/S00228-018-2509-2 |
0.71 |
|
| 2018 |
Ayalasomayajula S, Schuehly U, Pal P, Chen F, Zhou W, Sunkara G, Langenickel TH. Effect of the angiotensin receptor neprilysin inhibitor sacubitril/valsartan on pharmacokinetics and pharmacodynamics of a single-dose of furosemide. British Journal of Clinical Pharmacology. PMID 29318651 DOI: 10.1111/Bcp.13505 |
0.725 |
|
| 2017 |
Jain JP, Leong FJ, Chen L, Kalluri S, Koradia V, Stein DS, Wolf MC, Sunkara G, Kota J. Bioavailability of lumefantrine is significantly enhanced with a novel formulation approach: A randomized, open-label pharmacokinetic study in healthy volunteers. Antimicrobial Agents and Chemotherapy. PMID 28630183 DOI: 10.1128/Aac.00868-17 |
0.413 |
|
| 2017 |
Hsiao HL, Langenickel TH, Petruck J, Kode K, Ayalasomayajula S, Schuehly U, Greeley M, Pal P, Zhou W, Prescott MF, Sunkara G, Rajman I. Evaluation of pharmacokinetic and pharmacodynamic drug-drug interaction of sacubitril/valsartan (LCZ696) and sildenafil in patients with mild-to-moderate hypertension. Clinical Pharmacology and Therapeutics. PMID 28599060 DOI: 10.1002/Cpt.759 |
0.73 |
|
| 2017 |
Ayalasomayajula S, Langenickel T, Pal P, Boggarapu S, Sunkara G. Erratum to: Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor. Clinical Pharmacokinetics. PMID 28527109 DOI: 10.1007/s40262-017-0558-9 |
0.7 |
|
| 2017 |
Ayalasomayajula S, Langenickel T, Pal P, Boggarapu S, Sunkara G. Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor. Clinical Pharmacokinetics. PMID 28417439 DOI: 10.1007/S40262-017-0543-3 |
0.716 |
|
| 2016 |
Sun H, Ting L, Machineni S, Praestgaard J, Kuemmell A, Stein DS, Sunkara G, Kovacs SJ, Villano S, Tanaka SK. A Randomized, Open-label Study of the Pharmacokinetics and Safety of Oral and Intravenous Administration of Omadacycline to Healthy Subjects. Antimicrobial Agents and Chemotherapy. PMID 27736760 DOI: 10.1128/Aac.01393-16 |
0.39 |
|
| 2016 |
Ayalasomayajula S, Langenickel TH, Chandra P, Wolfson ED, Albrecht D, Zhou W, Pal P, Rajman I, Sunkara G. Effect of food on the oral bioavailability of the angiotensin receptor neprilysin inhibitor sacubitril/valsartan (LCZ696) in healthy subjects
. International Journal of Clinical Pharmacology and Therapeutics. PMID 27719743 DOI: 10.5414/CP202604 |
0.694 |
|
| 2016 |
Akahori M, Ayalasomayajula S, Langenickel T, Pal P, Zhou W, Sunkara G. Pharmacokinetics After Single Ascending Dose, Food Effect, and Safety of Sacubitril/Valsartan (LCZ696), an Angiotensin Receptor and Neprilysin Inhibitor, in Healthy Japanese Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 27324506 DOI: 10.1007/S13318-016-0354-1 |
0.726 |
|
| 2016 |
Ayalasomayajula S, Pan W, Han Y, Yang F, Langenickel T, Pal P, Zhou W, Yuan Y, Rajman I, Sunkara G. Assessment of Drug-Drug Interaction Potential Between Atorvastatin and LCZ696, A Novel Angiotensin Receptor Neprilysin Inhibitor, in Healthy Chinese Male Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 27245340 DOI: 10.1007/S13318-016-0349-Y |
0.731 |
|
| 2016 |
Ayalasomayajula SP, Langenickel TH, Jordaan P, Zhou W, Chandra P, Albrecht D, Pal P, Rajman I, Sunkara G. Effect of renal function on the pharmacokinetics of LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor. European Journal of Clinical Pharmacology. PMID 27230850 DOI: 10.1007/S00228-016-2072-7 |
0.695 |
|
| 2016 |
Bende G, Biswal S, Bhad P, Chen Y, Salunke A, Winter S, Wagner R, Sunkara G. Relative bioavailability of diclofenac potassium from softgel capsule versus powder for oral solution and immediate-release tablet formulation. Clinical Pharmacology in Drug Development. 5: 76-82. PMID 27119581 DOI: 10.1002/Cpdd.215 |
0.335 |
|
| 2016 |
Chitnis SD, Han Y, Yamaguchi M, Mita S, Zhao R, Sunkara G, Kulmatycki K. Population pharmacokinetic modeling and noncompartmental analysis demonstrated bioequivalence between metformin component of metformin/vildagliptin fixed-dose combination products and metformin immediate-release tablet sourced from various countries. Clinical Pharmacology in Drug Development. 5: 40-51. PMID 27119577 DOI: 10.1002/Cpdd.191 |
0.321 |
|
| 2016 |
Gan L, Jiang X, Mendonza A, Swan T, Reynolds C, Nguyen J, Pal P, Neelakantham S, Dahlke M, Langenickel T, Rajman I, Akahori M, Zhou W, Rebello S, Sunkara G. Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects. Clinical Pharmacology in Drug Development. 5: 27-39. PMID 27119576 DOI: 10.1002/Cpdd.181 |
0.475 |
|
| 2016 |
Han Y, Ayalasomayajula S, Pan W, Yang F, Yuan Y, Langenickel T, Hinder M, Kalluri S, Pal P, Sunkara G. Pharmacokinetics, Safety and Tolerability of Sacubitril/Valsartan (LCZ696) After Single-Dose Administration in Healthy Chinese Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 26961539 DOI: 10.1007/S13318-016-0328-3 |
0.746 |
|
| 2016 |
Huskey SW, Zhu CQ, Fredenhagen A, Kuhnol J, Luneau A, Jian Z, Yang Z, Miao Z, Yang F, Jain JP, Sunkara G, Mangold JB, Stein DS. KAE609 (Cipargamin), a new spiroindolone agent for the treatment of malaria: Evaluation of the Absorption, Distribution, Metabolism and Excretion of a single oral 300 mg dose of [14C]KAE609 in healthy male subjects. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26921387 DOI: 10.1124/Dmd.115.069187 |
0.326 |
|
| 2016 |
Gan L, Jiang X, Mendonza A, Swan T, Reynolds C, Nguyen J, Pal P, Neelakantham S, Dahlke M, Langenickel T, Rajman I, Akahori M, Zhou W, Rebello S, Sunkara G. Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects Clinical Pharmacology in Drug Development. 5: 27-39. DOI: 10.1002/cpdd.181 |
0.312 |
|
| 2015 |
Hsiao HL, Langenickel TH, Greeley M, Roberts J, Zhou W, Pal P, Rebello S, Rajman I, Sunkara G. Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol. Clinical Pharmacology in Drug Development. 4: 407-417. PMID 27137712 DOI: 10.1002/Cpdd.183 |
0.459 |
|
| 2015 |
Barve A, Kovacs SJ, Ke J, Crabbe R, Grosgurin P, Menetrey A, Nicolas-Métral V, Dabovic K, Dole K, Zhang J, Praestgaard J, Sunkara G, Stein D. The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans. Clinical Pharmacology in Drug Development. 4: 25-32. PMID 27128001 DOI: 10.1002/Cpdd.114 |
0.395 |
|
| 2015 |
Mendonza A, Hanna I, Meyers D, Koo P, Neelakantham S, Zhu B, Majumdar T, Rebello S, Sunkara G, Chen J. Assessment of pharmacokinetic drug-drug interaction between pradigastat and atazanavir or probenecid. Journal of Clinical Pharmacology. PMID 26189431 DOI: 10.1002/Jcph.595 |
0.397 |
|
| 2015 |
Gan L, Langenickel T, Petruck J, Kode K, Rajman I, Chandra P, Zhou W, Rebello S, Sunkara G. Effects of age and sex on the pharmacokinetics of LCZ696, an angiotensin receptor neprilysin inhibitor. Journal of Clinical Pharmacology. PMID 26073563 DOI: 10.1002/Jcph.571 |
0.374 |
|
| 2015 |
Ayalasomayajula SP, Meyers CD, Yu J, Kagan M, Matott R, Pal P, Majumdar T, Su Z, Crissey A, Rebello S, Sunkara G, Chen J. Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor. Biopharmaceutics & Drug Disposition. PMID 25963481 DOI: 10.1002/Bdd.1958 |
0.711 |
|
| 2015 |
Ayalasomayajula S, Meyers D, Koo P, Salunke A, Majumdar T, Rebello S, Sunkara G, Chen J. Assessment of pharmacokinetic drug-drug interaction between pradigastat and acetaminophen in healthy subjects. European Journal of Clinical Pharmacology. 71: 425-32. PMID 25724644 DOI: 10.1007/S00228-015-1822-2 |
0.714 |
|
| 2015 |
Hirano M, Meyers D, Golla G, Pal P, Pinot P, Lin T, Majumdar T, Rebello S, Sunkara G, Chen J. Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor. Clinical Pharmacokinetics. 54: 761-70. PMID 25633714 DOI: 10.1007/S40262-015-0235-9 |
0.316 |
|
| 2015 |
Ayalasomayajula S, Jordaan P, MBChB, Pal P, Ch P, ra, Albrecht D, Langenickel T, Rajman I, Sunkara G. Assessment of Drug Interaction Potential between LCZ696, an Angiotensin Receptor Neprilysin Inhibitor, and Digoxin or Warfa rin Clinical Pharmacology & Biopharmaceutics. 2015. DOI: 10.4172/2167-065X.1000147 |
0.742 |
|
| 2014 |
Sunkara G, Jiang X, Reynolds C, Serra D, Zhang Y, Ligueros-Saylan M, Ayalasomayajula S, Winter S, Jarugula V. Effect of food on the oral bioavailability of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide fixed dose combination tablets in healthy subjects. Clinical Pharmacology in Drug Development. 3: 487-92. PMID 27129123 DOI: 10.1002/Cpdd.131 |
0.715 |
|
| 2014 |
Sunkara G, Bende G, Mendonza AE, Solar-Yohay S, Biswal S, Neelakantham S, Wagner R, Flarakos J, Zhang Y, Jarugula V. Bioavailability of valsartan oral dosage forms. Clinical Pharmacology in Drug Development. 3: 132-8. PMID 27128457 DOI: 10.1002/Cpdd.56 |
0.336 |
|
| 2014 |
Xia B, Barve A, Heimbach T, Zhang T, Gu H, Wang L, Einolf H, Alexander N, Hanna I, Ke J, Mangold JB, He H, Sunkara G. Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 63: 103-12. PMID 25008118 DOI: 10.1016/J.Ejps.2014.06.021 |
0.382 |
|
| 2014 |
Yan JH, Meyers D, Lee Z, Danis K, Neelakantham S, Majumdar T, Rebello S, Sunkara G, Chen J. Pharmacokinetic and pharmacodynamic drug-drug interaction assessment between pradigastat and digoxin or warfarin. Journal of Clinical Pharmacology. 54: 800-8. PMID 24619917 DOI: 10.1002/Jcph.285 |
0.371 |
|
| 2013 |
Kovacs SJ, Ke J, Praestgaard J, Barve A, Zhang J, Maietta R, Sunkara G, Stein DS. Sa1031 Mild to Moderate Hepatic Impairment Has No Effect on the Single Dose Pharmacokinetics of Alisporivir (ALV) Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63629-X |
0.3 |
|
| 2012 |
Duan J, Chen J, Yin Q, Karan R, Meiser K, Smith HT, Sunkara G. Pharmacokinetics of single and multiple oral doses of valsartan/amlodipine (80/5 mg) in healthy Chinese subjects. International Journal of Clinical Pharmacology and Therapeutics. 50: 33-43. PMID 22192643 DOI: 10.5414/CP201601 |
0.303 |
|
| 2012 |
Jain JP, Lakshminarayana SB, Lefèvre G, Sivasubramanian R, Blasco F, Sunkara G. Differences in the pharmacokinetics of currently approved antimalarial drugs in uncomplicated malaria patients compared to healthy subjects Malaria Journal. 11: 118. DOI: 10.1186/1475-2875-11-S1-P118 |
0.378 |
|
| 2011 |
Bhad P, Ayalasomayajula S, Karan R, Leon S, Riviere GJ, Sunkara G, Jarugula V. Evaluation of pharmacokinetic interactions between amlodipine, valsartan, and hydrochlorothiazide in patients with hypertension. Journal of Clinical Pharmacology. 51: 933-42. PMID 20852001 DOI: 10.1177/0091270010376963 |
0.715 |
|
| 2010 |
Sunkara G, Ayalasomayajula SP, DeRuiter J, Kompella UB. Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor. Brain Research Bulletin. 81: 327-32. PMID 19761819 DOI: 10.1016/J.Brainresbull.2009.09.001 |
0.751 |
|
| 2010 |
Sunkara G, Yeh C, Ligueros-Saylan M, Kawashita H, Koseki N, Fukui Y. Assessment of Ethnic Differences in the Pharmacokinetics and Pharmacodynamics of Valsartan Journal of Bioequivalence & Bioavailability. 2: 120-124. DOI: 10.4172/Jbb.1000043 |
0.402 |
|
| 2009 |
Habtemariam B, Sallas W, Sunkara G, Kern S, Jarugula V, Pillai G. Population pharmacokinetics of valsartan in pediatrics. Drug Metabolism and Pharmacokinetics. 24: 145-52. PMID 19430170 DOI: 10.2133/Dmpk.24.145 |
0.317 |
|
| 2009 |
Blumer J, Batisky DL, Wells T, Shi V, Solar-Yohay S, Sunkara G. Pharmacokinetics of valsartan in pediatric and adolescent subjects with hypertension. Journal of Clinical Pharmacology. 49: 235-41. PMID 19179299 DOI: 10.1177/0091270008329547 |
0.367 |
|
| 2008 |
He YL, Ligueros-Saylan M, Sunkara G, Sabo R, Zhao C, Wang Y, Campestrini J, Pommier F, Dole K, Marion A, Dole WP, Howard D. Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects. Journal of Clinical Pharmacology. 48: 85-95. PMID 17986525 DOI: 10.1177/0091270007307880 |
0.483 |
|
| 2007 |
Ayalasomayajula SP, Dole K, He YL, Ligueros-Saylan M, Wang Y, Campestrini J, Humbert H, Sunkara G. Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects. Current Medical Research and Opinion. 23: 2913-20. PMID 17931461 DOI: 10.1185/030079907X233296 |
0.72 |
|
| 2007 |
He YL, Sabo R, Sunkara G, Bizot MN, Riviere GJ, Leon S, Ligueros-Saylan M, Dole WP, Howard D. Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers. Journal of Clinical Pharmacology. 47: 998-1004. PMID 17660482 DOI: 10.1177/0091270007301802 |
0.41 |
|
| 2007 |
Sunkara G, Sabo R, Wang Y, He YL, Campestrini J, Rosenberg M, Howard D, Dole WP. Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers. Journal of Clinical Pharmacology. 47: 1152-8. PMID 17656620 DOI: 10.1177/0091270007304313 |
0.394 |
|
| 2007 |
He YL, Sabo R, Riviere GJ, Sunkara G, Leon S, Ligueros-Saylan M, Rosenberg M, Dole WP, Howard D. Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Current Medical Research and Opinion. 23: 1131-8. PMID 17519080 DOI: 10.1185/030079907X188008 |
0.422 |
|
| 2007 |
Sunkara G, Reynolds CV, Pommier F, Humbert H, Yeh C, Prasad P. Evaluation of a pharmacokinetic interaction between valsartan and simvastatin in healthy subjects. Current Medical Research and Opinion. 23: 631-40. PMID 17355744 DOI: 10.1185/030079906X167471 |
0.426 |
|
| 2005 |
Sunkara G, Thang‐Dittman C, Yeh C, Ligueros‐Saylan M, Prasad P, Masuda N, Koseki N, Fukui Y. Assessment of ethnic differences in the pharmacokinetics of valsartan Clinical Pharmacology & Therapeutics. 77: 79. DOI: 10.1016/J.Clpt.2004.12.194 |
0.348 |
|
| 2004 |
Sabia H, Sunkara G, Ligueros-Saylan M, Wang Y, Smith H, McLeod J, Prasad P. Effect of a selective CYP2C9 inhibitor on the pharmacokinetics of nateglinide in healthy subjects. European Journal of Clinical Pharmacology. 60: 407-12. PMID 15197517 DOI: 10.1007/S00228-004-0778-4 |
0.402 |
|
| 2004 |
Sunkara G, Ayalasomayajula SP, Rao CS, Vennerstrom JL, DeRuiter J, Kompella UB. Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor. The Journal of Pharmacy and Pharmacology. 56: 351-8. PMID 15025860 DOI: 10.1211/0022357022908 |
0.757 |
|
| 2004 |
Sunkara G, Bigler H, Wang Y, Smith H, Prasad P, McLeod J, Ligueros-Saylan M. The effect of nateglinide on the pharmacokinetics and pharmacodynamics of acenocoumarol. Current Medical Research and Opinion. 20: 41-8. PMID 14741071 DOI: 10.1185/030079903125002685 |
0.386 |
|
| 2003 |
Koushik K, Sunkara G, Gwilt P, Kompella UB. Pathways and kinetics of deslorelin degradation in an airway epithelial cell line (Calu-1). Pharmaceutical Research. 20: 779-87. PMID 12751634 DOI: 10.1023/A:1023489620394 |
0.723 |
|
| 2002 |
Aukunuru JV, Sunkara G, Ayalasomayajula SP, DeRuiter J, Clark RC, Kompella UB. A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications. Pharmaceutical Research. 19: 278-85. PMID 11934234 DOI: 10.1023/A:1014438800893 |
0.718 |
|
| 2001 |
Sunkara G, Kompella UB. Controlled release of bioactive materials--28th international symposium. Carbohydrate drug carriers: cyclodextrins and chitosans. Idrugs : the Investigational Drugs Journal. 4: 1014-6. PMID 15965845 |
0.475 |
|
| 2001 |
Aukunuru JV, Sunkara G, Bandi N, Thoreson WB, Kompella UB. Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor. Pharmaceutical Research. 18: 565-72. PMID 11465409 DOI: 10.1023/A:1011060705599 |
0.716 |
|
| 2000 |
Sunkara G, Deruiter J, Clark CR, Kompella UB. In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor. The Journal of Pharmacy and Pharmacology. 52: 1113-22. PMID 11045892 DOI: 10.1211/0022357001774877 |
0.541 |
|
| 1999 |
Kompella UB, Sunkara G, Thomas E, Clark CR, Deruiter J. Rabbit corneal and conjunctival permeability of the novel aldose reductase inhibitors: N-[[4-(benzoylamino)phenyl] sulphonyl]glycines and N-benzoyl-N-phenylglycines. The Journal of Pharmacy and Pharmacology. 51: 921-7. PMID 10504031 DOI: 10.1211/0022357991773357 |
0.529 |
|
| 1999 |
Sunkara G, Navarre CB, Kompella UB. Influence of pH and temperature on kinetics of ceftiofur degradation in aqueous solutions. The Journal of Pharmacy and Pharmacology. 51: 249-55. PMID 10344624 DOI: 10.1211/0022357991772411 |
0.492 |
|
| 1999 |
Navarre CB, Zhang L, Sunkara G, Duran SH, Kompella UB. Ceftiofur distribution in plasma and joint fluid following regional limb injection in cattle. Journal of Veterinary Pharmacology and Therapeutics. 22: 13-9. PMID 10211712 DOI: 10.1046/J.1365-2885.1999.00186.X |
0.51 |
|
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