Gangadhar Sunkara, Ph.D. - Publications

Affiliations: 
2002 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Pharmacy, Pharmaceutical Chemistry, Ophthalmology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lin W, Heimbach T, Jain JP, Awasthi R, Hamed K, Sunkara G, He H. A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients. Journal of Pharmaceutical Sciences. PMID 27506269 DOI: 10.1016/j.xphs.2016.06.026  0.84
2016 Akahori M, Ayalasomayajula S, Langenickel T, Pal P, Zhou W, Sunkara G. Pharmacokinetics After Single Ascending Dose, Food Effect, and Safety of Sacubitril/Valsartan (LCZ696), an Angiotensin Receptor and Neprilysin Inhibitor, in Healthy Japanese Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 27324506 DOI: 10.1007/s13318-016-0354-1  0.84
2016 Ayalasomayajula S, Han Y, Langenickel T, Malcolm K, Zhou W, Hanna I, Alexander N, Natrillo A, Goswami B, Hinder M, Sunkara G. In vitro and clinical evaluation of OATP-mediated drug interaction potential of sacubitril/valsartan (LCZ696). Journal of Clinical Pharmacy and Therapeutics. PMID 27321165 DOI: 10.1111/jcpt.12408  0.84
2016 Ayalasomayajula S, Pan W, Han Y, Yang F, Langenickel T, Pal P, Zhou W, Yuan Y, Rajman I, Sunkara G. Assessment of Drug-Drug Interaction Potential Between Atorvastatin and LCZ696, A Novel Angiotensin Receptor Neprilysin Inhibitor, in Healthy Chinese Male Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 27245340 DOI: 10.1007/s13318-016-0349-y  0.84
2016 Ayalasomayajula SP, Langenickel TH, Jordaan P, Zhou W, Chandra P, Albrecht D, Pal P, Rajman I, Sunkara G. Effect of renal function on the pharmacokinetics of LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor. European Journal of Clinical Pharmacology. PMID 27230850 DOI: 10.1007/s00228-016-2072-7  0.84
2016 Sun H, Van LM, Floch D, Jiang X, Klein UR, Abrams K, Sunkara G. Pharmacokinetics and Pharmacodynamics of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis. Journal of Clinical Pharmacology. PMID 27119439 DOI: 10.1002/jcph.754  0.84
2016 Han Y, Ayalasomayajula S, Pan W, Yang F, Yuan Y, Langenickel T, Hinder M, Kalluri S, Pal P, Sunkara G. Pharmacokinetics, Safety and Tolerability of Sacubitril/Valsartan (LCZ696) After Single-Dose Administration in Healthy Chinese Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 26961539 DOI: 10.1007/s13318-016-0328-3  0.84
2016 Huskey SW, Zhu CQ, Fredenhagen A, Kuhnol J, Luneau A, Jian Z, Yang Z, Miao Z, Yang F, Jain JP, Sunkara G, Mangold JB, Stein DS. KAE609 (Cipargamin), a new spiroindolone agent for the treatment of malaria: Evaluation of the Absorption, Distribution, Metabolism and Excretion of a single oral 300 mg dose of [14C]KAE609 in healthy male subjects. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26921387 DOI: 10.1124/dmd.115.069187  0.84
2016 Bende G, Biswal S, Bhad P, Chen Y, Salunke A, Winter S, Wagner R, Sunkara G. Relative bioavailability of diclofenac potassium from softgel capsule versus powder for oral solution and immediate-release tablet formulation Clinical Pharmacology in Drug Development. 5: 76-82. DOI: 10.1002/cpdd.215  0.84
2016 Chitnis SD, Han Y, Yamaguchi M, Mita S, Zhao R, Sunkara G, Kulmatycki K. Population pharmacokinetic modeling and noncompartmental analysis demonstrated bioequivalence between metformin component of metformin/vildagliptin fixed-dose combination products and metformin immediate-release tablet sourced from various countries Clinical Pharmacology in Drug Development. 5: 40-51. DOI: 10.1002/cpdd.191  0.84
2016 Gan L, Jiang X, Mendonza A, Swan T, Reynolds C, Nguyen J, Pal P, Neelakantham S, Dahlke M, Langenickel T, Rajman I, Akahori M, Zhou W, Rebello S, Sunkara G. Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects Clinical Pharmacology in Drug Development. 5: 27-39. DOI: 10.1002/cpdd.181  0.84
2015 Mendonza A, Hanna I, Meyers D, Koo P, Neelakantham S, Zhu B, Majumdar T, Rebello S, Sunkara G, Chen J. Assessment of pharmacokinetic drug-drug interaction between pradigastat and atazanavir or probenecid. Journal of Clinical Pharmacology. PMID 26189431 DOI: 10.1002/jcph.595  0.84
2015 Gan L, Langenickel T, Petruck J, Kode K, Rajman I, Chandra P, Zhou W, Rebello S, Sunkara G. Effects of age and sex on the pharmacokinetics of LCZ696, an angiotensin receptor neprilysin inhibitor. Journal of Clinical Pharmacology. PMID 26073563 DOI: 10.1002/jcph.571  0.84
2015 Ayalasomayajula SP, Meyers CD, Yu J, Kagan M, Matott R, Pal P, Majumdar T, Su Z, Crissey A, Rebello S, Sunkara G, Chen J. Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor. Biopharmaceutics & Drug Disposition. PMID 25963481 DOI: 10.1002/bdd.1958  0.84
2015 Chen J, Bhansali S, Neelakantham S, Trusley C, Majumdar T, Rebello S, Sunkara G, Meyers C. Effect of pradigastat, a diacylglycerol acyltransferase 1 inhibitor, on the pharmacokinetics of a combination oral contraceptive in healthy female subjects. International Journal of Clinical Pharmacology and Therapeutics. 53: 317-24. PMID 25740268 DOI: 10.5414/CP202288  0.84
2015 Kulmatycki K, Hanna I, Meyers D, Salunke A, Movva A, Majumdar T, Natrillo A, Vapurcuyan A, Rebello S, Sunkara G, Chen J. Evaluation of a potential transporter-mediated drug interaction between rosuvastatin and pradigastat, a novel DGAT-1 inhibitor. International Journal of Clinical Pharmacology and Therapeutics. 53: 345-55. PMID 25740267 DOI: 10.5414/CP202275  0.84
2015 Ayalasomayajula S, Meyers D, Koo P, Salunke A, Majumdar T, Rebello S, Sunkara G, Chen J. Assessment of pharmacokinetic drug-drug interaction between pradigastat and acetaminophen in healthy subjects. European Journal of Clinical Pharmacology. 71: 425-32. PMID 25724644 DOI: 10.1007/s00228-015-1822-2  0.84
2015 Hirano M, Meyers D, Golla G, Pal P, Pinot P, Lin T, Majumdar T, Rebello S, Sunkara G, Chen J. Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor. Clinical Pharmacokinetics. 54: 761-70. PMID 25633714 DOI: 10.1007/s40262-015-0235-9  0.84
2015 Mita S, Meyers D, Pal P, Lin T, Majumdar T, Rebello S, Sunkara G, Chen J. Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor. Clinical Pharmacokinetics. 54: 751-60. PMID 25627776 DOI: 10.1007/s40262-015-0234-x  0.84
2015 Hsiao Hl, Langenickel TH, Greeley M, Roberts J, Zhou W, Pal P, Rebello S, Rajman I, Sunkara G. Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol Clinical Pharmacology in Drug Development. DOI: 10.1002/cpdd.183  0.84
2015 Barve A, Kovacs SJ, Ke J, Crabbe R, Grosgurin P, Menetrey A, Nicolas-Métral V, Dabovic K, Dole K, Zhang J, Praestgaard J, Sunkara G, Stein D. The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans Clinical Pharmacology in Drug Development. 4: 25-32. DOI: 10.1002/cpdd.114  0.84
2014 Sunkara G, Jiang X, Reynolds C, Serra D, Zhang Y, Ligueros-Saylan M, Ayalasomayajula S, Winter S, Jarugula V. Effect of food on the oral bioavailability of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide fixed dose combination tablets in healthy subjects. Clinical Pharmacology in Drug Development. 3: 487-92. PMID 27129123 DOI: 10.1002/cpdd.131  0.84
2014 Sunkara G, Bende G, Mendonza AE, Solar-Yohay S, Biswal S, Neelakantham S, Wagner R, Flarakos J, Zhang Y, Jarugula V. Bioavailability of valsartan oral dosage forms. Clinical Pharmacology in Drug Development. 3: 132-8. PMID 27128457 DOI: 10.1002/cpdd.56  0.84
2014 Xia B, Barve A, Heimbach T, Zhang T, Gu H, Wang L, Einolf H, Alexander N, Hanna I, Ke J, Mangold JB, He H, Sunkara G. Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 63: 103-12. PMID 25008118 DOI: 10.1016/j.ejps.2014.06.021  0.84
2014 Yan JH, Meyers D, Lee Z, Danis K, Neelakantham S, Majumdar T, Rebello S, Sunkara G, Chen J. Pharmacokinetic and pharmacodynamic drug-drug interaction assessment between pradigastat and digoxin or warfarin. Journal of Clinical Pharmacology. 54: 800-8. PMID 24619917 DOI: 10.1002/jcph.285  0.84
2013 Chakraborty A, Van LM, Skerjanec A, Floch D, Klein UR, Krammer G, Sunkara G, Howard D. Pharmacokinetic and pharmacodynamic properties of canakinumab in patients with gouty arthritis. Journal of Clinical Pharmacology. 53: 1240-51. PMID 24122883 DOI: 10.1002/jcph.162  0.84
2012 Duan J, Chen J, Yin Q, Karan R, Meiser K, Smith HT, Sunkara G. Pharmacokinetics of single and multiple oral doses of valsartan/amlodipine (80/5 mg) in healthy Chinese subjects. International Journal of Clinical Pharmacology and Therapeutics. 50: 33-43. PMID 22192643 DOI: 10.5414/CP201601  0.84
2012 Lin C, Sunkara G, Cannon JB, Ranade V. Recent advances in prodrugs as drug delivery systems. American Journal of Therapeutics. 19: 33-43. PMID 21150770 DOI: 10.1097/MJT.0b013e3181f47f3f  0.84
2011 Bhad P, Ayalasomayajula S, Karan R, Leon S, Riviere GJ, Sunkara G, Jarugula V. Evaluation of pharmacokinetic interactions between amlodipine, valsartan, and hydrochlorothiazide in patients with hypertension. Journal of Clinical Pharmacology. 51: 933-42. PMID 20852001 DOI: 10.1177/0091270010376963  0.84
2010 Sunkara G, Ayalasomayajula SP, DeRuiter J, Kompella UB. Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor. Brain Research Bulletin. 81: 327-32. PMID 19761819 DOI: 10.1016/j.brainresbull.2009.09.001  0.84
2009 Habtemariam B, Sallas W, Sunkara G, Kern S, Jarugula V, Pillai G. Population pharmacokinetics of valsartan in pediatrics. Drug Metabolism and Pharmacokinetics. 24: 145-52. PMID 19430170 DOI: JST.JSTAGE/dmpk/24.145  0.84
2009 Blumer J, Batisky DL, Wells T, Shi V, Solar-Yohay S, Sunkara G. Pharmacokinetics of valsartan in pediatric and adolescent subjects with hypertension. Journal of Clinical Pharmacology. 49: 235-41. PMID 19179299 DOI: 10.1177/0091270008329547  0.84
2008 He YL, Ligueros-Saylan M, Sunkara G, Sabo R, Zhao C, Wang Y, Campestrini J, Pommier F, Dole K, Marion A, Dole WP, Howard D. Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects. Journal of Clinical Pharmacology. 48: 85-95. PMID 17986525 DOI: 10.1177/0091270007307880  0.84
2007 Ayalasomayajula SP, Dole K, He YL, Ligueros-Saylan M, Wang Y, Campestrini J, Humbert H, Sunkara G. Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects. Current Medical Research and Opinion. 23: 2913-20. PMID 17931461 DOI: 10.1185/030079907X233296  0.84
2007 He YL, Sabo R, Sunkara G, Bizot MN, Riviere GJ, Leon S, Ligueros-Saylan M, Dole WP, Howard D. Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers. Journal of Clinical Pharmacology. 47: 998-1004. PMID 17660482 DOI: 10.1177/0091270007301802  0.84
2007 Sunkara G, Sabo R, Wang Y, He YL, Campestrini J, Rosenberg M, Howard D, Dole WP. Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers. Journal of Clinical Pharmacology. 47: 1152-8. PMID 17656620 DOI: 10.1177/0091270007304313  0.84
2007 He YL, Sabo R, Riviere GJ, Sunkara G, Leon S, Ligueros-Saylan M, Rosenberg M, Dole WP, Howard D. Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Current Medical Research and Opinion. 23: 1131-8. PMID 17519080 DOI: 10.1185/030079907X188008  0.84
2007 Sunkara G, Reynolds CV, Pommier F, Humbert H, Yeh C, Prasad P. Evaluation of a pharmacokinetic interaction between valsartan and simvastatin in healthy subjects. Current Medical Research and Opinion. 23: 631-40. PMID 17355744 DOI: 10.1185/030079906X167471  0.84
2004 Sabia H, Sunkara G, Ligueros-Saylan M, Wang Y, Smith H, McLeod J, Prasad P. Effect of a selective CYP2C9 inhibitor on the pharmacokinetics of nateglinide in healthy subjects. European Journal of Clinical Pharmacology. 60: 407-12. PMID 15197517 DOI: 10.1007/s00228-004-0778-4  0.84
2004 Sunkara G, Ayalasomayajula SP, Rao CS, Vennerstrom JL, DeRuiter J, Kompella UB. Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor. The Journal of Pharmacy and Pharmacology. 56: 351-8. PMID 15025860 DOI: 10.1211/0022357022908  0.84
2004 Sunkara G, Bigler H, Wang Y, Smith H, Prasad P, McLeod J, Ligueros-Saylan M. The effect of nateglinide on the pharmacokinetics and pharmacodynamics of acenocoumarol. Current Medical Research and Opinion. 20: 41-8. PMID 14741071 DOI: 10.1185/030079903125002685  0.84
2003 Conjeevaram R, Chaturvedula A, Betageri GV, Sunkara G, Banga AK. Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation. Pharmaceutical Research. 20: 1496-501. PMID 14567646 DOI: 10.1023/A:1025726715063  0.84
2003 Koushik K, Sunkara G, Gwilt P, Kompella UB. Pathways and kinetics of deslorelin degradation in an airway epithelial cell line (Calu-1). Pharmaceutical Research. 20: 779-87. PMID 12751634 DOI: 10.1023/A:1023489620394  0.84
2002 Aukunuru JV, Sunkara G, Ayalasomayajula SP, DeRuiter J, Clark RC, Kompella UB. A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications. Pharmaceutical Research. 19: 278-85. PMID 11934234 DOI: 10.1023/A:1014438800893  0.84
2001 Sunkara G, Kompella UB. Controlled release of bioactive materials--28th international symposium. Carbohydrate drug carriers: cyclodextrins and chitosans. Idrugs : the Investigational Drugs Journal. 4: 1014-6. PMID 15965845  0.96
2001 Sunkara G, Mada SR, Vobalaboina V. Pharmacokinetics and tissue distribution of piperine in animals after i.v. bolus administration Pharmazie. 56: 640-642. PMID 11534342  0.84
2001 Aukunuru JV, Sunkara G, Bandi N, Thoreson WB, Kompella UB. Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor. Pharmaceutical Research. 18: 565-72. PMID 11465409 DOI: 10.1023/A:1011060705599  0.84
2000 Sunkara G, Deruiter J, Clark CR, Kompella UB. In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor. The Journal of Pharmacy and Pharmacology. 52: 1113-22. PMID 11045892  0.84
1999 Kompella UB, Sunkara G, Thomas E, Clark CR, Deruiter J. Rabbit corneal and conjunctival permeability of the novel aldose reductase inhibitors: N-[[4-(benzoylamino)phenyl] sulphonyl]glycines and N-benzoyl-N-phenylglycines. The Journal of Pharmacy and Pharmacology. 51: 921-7. PMID 10504031 DOI: 10.1211/0022357991773357  0.84
1999 Sunkara G, Navarre CB, Kompella UB. Influence of pH and temperature on kinetics of ceftiofur degradation in aqueous solutions. The Journal of Pharmacy and Pharmacology. 51: 249-55. PMID 10344624  0.84
1999 Navarre CB, Zhang L, Sunkara G, Duran SH, Kompella UB. Ceftiofur distribution in plasma and joint fluid following regional limb injection in cattle. Journal of Veterinary Pharmacology and Therapeutics. 22: 13-9. PMID 10211712 DOI: 10.1046/j.1365-2885.1999.00186.x  0.84
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