| Year |
Citation |
Score |
| 2015 |
Valsangkar DS, Downs SM. Acetyl CoA carboxylase inactivation and meiotic maturation in mouse oocytes. Molecular Reproduction and Development. 82: 679-93. PMID 26043180 DOI: 10.1002/Mrd.22505 |
0.806 |
|
| 2015 |
Downs SM. Nutrient pathways regulating the nuclear maturation of mammalian oocytes. Reproduction, Fertility, and Development. 27: 572-82. PMID 25798589 DOI: 10.1071/Rd14343 |
0.447 |
|
| 2014 |
Ya R, Downs SM. Perturbing microtubule integrity blocks AMP-activated protein kinase-induced meiotic resumption in cultured mouse oocytes. Zygote (Cambridge, England). 22: 91-102. PMID 23199370 DOI: 10.1017/S0967199412000457 |
0.821 |
|
| 2013 |
Valsangkar D, Downs SM. A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. Biology of Reproduction. 89: 43. PMID 23863407 DOI: 10.1095/Biolreprod.113.109058 |
0.795 |
|
| 2013 |
Ya R, Downs SM. Suppression of chemically induced and spontaneous mouse oocyte activation by AMP-activated protein kinase. Biology of Reproduction. 88: 70. PMID 23390161 DOI: 10.1095/Biolreprod.112.106120 |
0.818 |
|
| 2012 |
Valsangkar D, Downs SM. Fatty Acid Oxidation and Hormone-Induced Meiotic Resumption in Mouse Oocytes. Biology of Reproduction. 87: 308-308. DOI: 10.1093/Biolreprod/87.S1.308 |
0.744 |
|
| 2011 |
Downs SM. Mouse versus rat: Profound differences in meiotic regulation at the level of the isolated oocyte. Molecular Reproduction and Development. 78: 778-94. PMID 21953615 DOI: 10.1002/Mrd.21377 |
0.489 |
|
| 2011 |
Valsangkar D, Downs SM. Acetyl CoA Carboxylase and Meiotic Maturation in Mouse Oocytes. Biology of Reproduction. 85: 597-597. DOI: 10.1093/Biolreprod/85.S1.597 |
0.765 |
|
| 2011 |
Ya R, Downs SM. Stimulation of AMP-Activated Protein Kinase Promotes Maturation and Suppresses Spontaneous Activation of Mouse Oocytes. Biology of Reproduction. 85: 596-596. DOI: 10.1093/Biolreprod/85.S1.596 |
0.807 |
|
| 2010 |
Downs SM, Ya R, Davis CC. Role of AMPK throughout meiotic maturation in the mouse oocyte: evidence for promotion of polar body formation and suppression of premature activation. Molecular Reproduction and Development. 77: 888-99. PMID 20830737 DOI: 10.1002/Mrd.21229 |
0.813 |
|
| 2010 |
Downs SM. Regulation of the G2/M transition in rodent oocytes. Molecular Reproduction and Development. 77: 566-85. PMID 20578061 DOI: 10.1002/Mrd.21175 |
0.364 |
|
| 2010 |
Ya R, Downs SM. Microtubule Integrity Influences the Activity and Localization of AMP-Activated Protein Kinase During Mouse Oocyte Maturation. Biology of Reproduction. 83: 325-325. DOI: 10.1093/Biolreprod/83.S1.325 |
0.794 |
|
| 2010 |
Downs SM. Mouse Versus Rat: Profound Differences in Meiotic Regulation at the Level of the Cumulus-Enclosed Oocyte. Biology of Reproduction. 83: 320-320. DOI: 10.1093/Biolreprod/83.S1.320 |
0.362 |
|
| 2009 |
Chen J, Chi MM, Moley KH, Downs SM. cAMP pulsing of denuded mouse oocytes increases meiotic resumption via activation of AMP-activated protein kinase. Reproduction (Cambridge, England). 138: 759-70. PMID 19700529 DOI: 10.1530/Rep-08-0535 |
0.534 |
|
| 2009 |
Downs SM, Mosey JL, Klinger J. Fatty acid oxidation and meiotic resumption in mouse oocytes. Molecular Reproduction and Development. 76: 844-53. PMID 19455666 DOI: 10.1093/Biolreprod/78.S1.135B |
0.605 |
|
| 2009 |
Downs SM, Davis C. The Participation of AMP-Activated Protein Kinase Throughout Meiotic Maturation in Mouse Oocytes. Biology of Reproduction. 81: 277-277. DOI: 10.1093/Biolreprod/81.S1.277 |
0.501 |
|
| 2008 |
Chen J, Downs SM. AMP-activated protein kinase is involved in hormone-induced mouse oocyte meiotic maturation in vitro. Developmental Biology. 313: 47-57. PMID 18048025 DOI: 10.1016/J.Ydbio.2007.09.043 |
0.559 |
|
| 2008 |
Downs SM, Chen J. EGF-like peptides mediate FSH-induced maturation of cumulus cell-enclosed mouse oocytes. Molecular Reproduction and Development. 75: 105-14. PMID 17549700 DOI: 10.1002/Mrd.20781 |
0.483 |
|
| 2007 |
LaRosa C, Downs SM. Meiotic induction by heat stress in mouse oocytes: involvement of AMP-activated protein kinase and MAPK family members. Biology of Reproduction. 76: 476-86. PMID 17108331 DOI: 10.1095/Biolreprod.106.057422 |
0.733 |
|
| 2007 |
Chen J, Downs S. AMP-ACTIVATED PROTEIN KINASE (AMPK) IS INVOLVED IN FOLLICLE-STIMULATING HORMONE (FSH)-INDUCED MOUSE OOCYTE MEIOTIC MATURATION Biology of Reproduction. 77: 141-141. DOI: 10.1093/Biolreprod/77.S1.141 |
0.591 |
|
| 2006 |
Downs SM, Chen J. Induction of meiotic maturation in mouse oocytes by adenosine analogs. Molecular Reproduction and Development. 73: 1159-68. PMID 16804878 DOI: 10.1002/Mrd.20439 |
0.572 |
|
| 2006 |
Chen J, Hudson E, Chi MM, Chang AS, Moley KH, Hardie DG, Downs SM. AMPK regulation of mouse oocyte meiotic resumption in vitro. Developmental Biology. 291: 227-38. PMID 16443210 DOI: 10.1016/J.Ydbio.2005.11.039 |
0.595 |
|
| 2006 |
Downs SM, Gilles R, Vanderhoef C, Humpherson PG, Leese HJ. Differential response of cumulus cell-enclosed and denuded mouse oocytes in a meiotic induction model system. Molecular Reproduction and Development. 73: 379-89. PMID 16362973 DOI: 10.1002/Mrd.20416 |
0.412 |
|
| 2006 |
LaRosa C, Downs SM. Stress stimulates AMP-activated protein kinase and meiotic resumption in mouse oocytes. Biology of Reproduction. 74: 585-92. PMID 16280415 DOI: 10.1095/Biolreprod.105.046524 |
0.752 |
|
| 2005 |
LaRosa C, Downs SM. MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism. Molecular Reproduction and Development. 70: 235-45. PMID 15570612 DOI: 10.1002/Mrd.20200 |
0.775 |
|
| 2004 |
Colton SA, Downs SM. Potential role for the sorbitol pathway in the meiotic dysfunction exhibited by oocytes from diabetic mice. Journal of Experimental Zoology. Part a, Comparative Experimental Biology. 301: 439-48. PMID 15114651 DOI: 10.1002/Jez.A.20070 |
0.439 |
|
| 2003 |
Downs SM, Verhoeven A. Glutamine and the maintenance of meiotic arrest in mouse oocytes: influence of culture medium, glucose, and cumulus cells. Molecular Reproduction and Development. 66: 90-7. PMID 12874804 DOI: 10.1002/Mrd.10326 |
0.442 |
|
| 2003 |
Colton SA, Humpherson PG, Leese HJ, Downs SM. Physiological changes in oocyte-cumulus cell complexes from diabetic mice that potentially influence meiotic regulation. Biology of Reproduction. 69: 761-70. PMID 12724281 DOI: 10.1095/Biolreprod.102.013649 |
0.383 |
|
| 2002 |
Downs SM. The biochemistry of oocyte maturation Ernst Schering Research Foundation Workshop. 81-99. PMID 12402541 |
0.394 |
|
| 2002 |
Colton SA, Pieper GM, Downs SM. Altered meiotic regulation in oocytes from diabetic mice Biology of Reproduction. 67: 220-231. PMID 12080021 DOI: 10.1095/Biolreprod67.1.220 |
0.383 |
|
| 2002 |
Downs SM, Hudson ER, Hardie DG. A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes. Developmental Biology. 245: 200-12. PMID 11969266 DOI: 10.1006/Dbio.2002.0613 |
0.593 |
|
| 2002 |
Downs SM, Humpherson PG, Leese HJ. Pyruvate utilization by mouse oocytes is influenced by meiotic status and the cumulus oophorus Molecular Reproduction and Development. 62: 113-123. PMID 11933168 DOI: 10.1002/Mrd.10067 |
0.453 |
|
| 2001 |
Downs SM. A gap-junction-mediated signal, rather than an external paracrine factor, predominates during meiotic induction in isolated mouse oocytes Zygote. 9: 71-82. PMID 11273034 DOI: 10.1017/S0967199401001071 |
0.422 |
|
| 2001 |
Downs SM, Cottom J, Hunzicker-Dunn M. Protein kinase C and meiotic regulation in isolated mouse oocytes Molecular Reproduction and Development. 58: 101-115. PMID 11144213 DOI: 10.1002/1098-2795(200101)58:1<101::Aid-Mrd13>3.0.Co;2-J |
0.575 |
|
| 2001 |
Downs SM, Ruan B, Schroepfer J. Meiosis-activating sterol and the maturation of isolated mouse oocytes Biology of Reproduction. 64: 80-89. PMID 11133661 DOI: 10.1095/Biolreprod64.1.80 |
0.503 |
|
| 2000 |
Downs SM, Hudson ED. Energy substrates and the completion of spontaneous meiotic maturation Zygote. 8: 339-351. PMID 11108555 DOI: 10.1017/S0967199400001131 |
0.382 |
|
| 2000 |
Downs SM. Adenosine blocks hormone-induced meiotic maturation by suppressing purine de novo synthesis Molecular Reproduction and Development. 56: 172-179. PMID 10813849 DOI: 10.1002/(Sici)1098-2795(200006)56:2<172::Aid-Mrd8>3.0.Co;2-2 |
0.557 |
|
| 1999 |
Downs SM. Uptake and metabolism of adenosine mediate a meiosis-arresting action on mouse oocytes Molecular Reproduction and Development. 53: 208-221. PMID 10331459 DOI: 10.1002/(Sici)1098-2795(199906)53:2<208::Aid-Mrd10>3.0.Co;2-O |
0.465 |
|
| 1999 |
Downs SM, Utecht AM. Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes Biology of Reproduction. 60: 1446-1452. PMID 10330104 DOI: 10.1095/Biolreprod60.6.1446 |
0.346 |
|
| 1998 |
Downs SM. Precursors of the purine backbone augment the inhibitory action of hypoxanthine and dibutyryl cAMP on mouse oocyte maturation Journal of Experimental Zoology. 282: 376-384. PMID 9755485 DOI: 10.1002/(Sici)1097-010X(19981015)282:3<376::Aid-Jez10>3.0.Co;2-D |
0.412 |
|
| 1998 |
Downs SM, Humpherson PG, Leese HJ. Meiotic induction in cumulus cell-enclosed mouse oocytes: Involvement of the pentose phosphate pathway Biology of Reproduction. 58: 1084-1094. PMID 9546744 DOI: 10.1095/Biolreprod58.4.1084 |
0.492 |
|
| 1997 |
Downs SM, Houghton FD, Humpherson PG, Leese HJ. Substrate utilization and maturation of cumulus cell-enclosed mouse oocytes: Evidence that pyruvate oxidation does not mediate meiotic induction Journal of Reproduction and Fertility. 110: 1-10. PMID 9227351 DOI: 10.1530/Jrf.0.1100001 |
0.427 |
|
| 1997 |
Downs SM. Hypoxanthine regulation of oocyte maturation in the mouse: Insights using hypoxanthine phosphoribosyltransferase-deficient animals Biology of Reproduction. 57: 54-62. PMID 9209080 DOI: 10.1095/Biolreprod57.1.54 |
0.557 |
|
| 1997 |
Downs SM, Mastropolo AM. Culture conditions affect meiotic regulation in cumulus cell-enclosed mouse oocytes Molecular Reproduction and Development. 46: 551-566. PMID 9094102 DOI: 10.1002/(Sici)1098-2795(199704)46:4<551::Aid-Mrd13>3.0.Co;2-Z |
0.457 |
|
| 1997 |
Downs SM. Involvement of purine nucleotide synthetic pathways in gonadotropin- induced meiotic maturation in mouse cumulus cell-enclosed oocytes Molecular Reproduction and Development. 46: 155-167. PMID 9021747 DOI: 10.1002/(Sici)1098-2795(199702)46:2<155::Aid-Mrd6>3.0.Co;2-P |
0.558 |
|
| 1997 |
Dienhart MK, O'Brien MJ, Downs SM. Uptake and salvage of hypoxanthine mediates developmental arrest in preimplantation mouse embryos Biology of Reproduction. 56: 1-13. PMID 9002627 DOI: 10.1095/Biolreprod56.1.1 |
0.455 |
|
| 1996 |
Dienhart MK, Downs SM. Cyclic AMP reversal of hypoxanthine-arrested preimplantation mouse embryos is EDTA-dependent Zygote. 4: 129-137. PMID 8913026 DOI: 10.1017/S0967199400003002 |
0.461 |
|
| 1996 |
Downs SM, Humpherson PG, Martin KL, Leese HJ. Glucose utilization during gonadotropin-induced meiotic maturation in cumulus cell-enclosed mouse oocytes. Molecular Reproduction and Development. 44: 121-31. PMID 8722700 DOI: 10.1002/(Sici)1098-2795(199605)44:1<121::Aid-Mrd14>3.0.Co;2-7 |
0.442 |
|
| 1995 |
Downs SM. The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte Developmental Biology. 167: 502-512. PMID 7875374 DOI: 10.1006/Dbio.1995.1044 |
0.481 |
|
| 1995 |
Downs SM, Hunzicker-Dunn M. Differential Regulation of Oocyte Maturation and Cumulus Expansion in the Mouse Oocyte- Cumulus Cell Complex by Site-Selective Analogs of Cyclic Adenosine Monophosphate Developmental Biology. 172: 72-85. PMID 7589815 DOI: 10.1006/Dbio.1995.0006 |
0.439 |
|
| 1994 |
Downs SM, Mastropolo AM. The participation of energy substrates in the control of meiotic maturation in murine oocytes Developmental Biology. 162: 154-168. PMID 8125183 DOI: 10.1006/Dbio.1994.1075 |
0.468 |
|
| 1994 |
Downs SM. High performance liquid chromatography analysis of hypoxanthine metabolism in mouse oocyte-cumulus cell complexes: Effects of purine metabolic perturbants Biology of Reproduction. 50: 1403-1412. PMID 8080928 DOI: 10.1095/Biolreprod50.6.1403 |
0.342 |
|
| 1994 |
Downs SM. Induction of meiotic maturation in vivo in the mouse by IMP dehydrogenase inhibitors: Effects on the developmental capacity of ova Molecular Reproduction and Development. 38: 293-302. PMID 7917281 DOI: 10.1002/Mrd.1080380310 |
0.423 |
|
| 1993 |
Downs SM. Purine control of mouse oocyte maturation: Evidence that nonmetabolized hypoxanthine maintains meiotic arrest Molecular Reproduction and Development. 35: 82-94. PMID 8099493 DOI: 10.1002/Mrd.1080350114 |
0.538 |
|
| 1993 |
Downs S. Factors affecting the resumption of meiotic maturation in mammalian oocytes Theriogenology. 39: 65-79. DOI: 10.1016/0093-691X(93)90024-Y |
0.389 |
|
| 1992 |
Fagbohun CF, Downs SM. Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes Journal of Reproduction and Fertility. 96: 681-697. PMID 1339848 |
0.341 |
|
| 1992 |
Downs SM, Buccione R, Eppig JJ. Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G-proteins Journal of Experimental Zoology. 262: 391-404. PMID 1320658 DOI: 10.1002/Jez.1402620405 |
0.497 |
|
| 1991 |
Downs SM, Dow MP. Hypoxanthine-maintained two-cell block in mouse embryos: dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors. Biology of Reproduction. 44: 1025-39. PMID 1873380 DOI: 10.1095/Biolreprod44.6.1025 |
0.374 |
|
| 1991 |
Fagbohun CF, Downs SM. Metabolic coupling and ligand-stimulated meiotic maturation in the mouse oocyte-cumulus cell complex Biology of Reproduction. 45: 851-859. PMID 1666851 DOI: 10.1095/Biolreprod45.6.851 |
0.465 |
|
| 1991 |
Downs SM, Dow MP, Fagbohun CF. The meiotic response of cumulus cell-enclosed mouse oocytes to follicle-stimulating hormone in the presence of different macromolecules. The Journal of Experimental Zoology. 258: 373-83. PMID 1653817 DOI: 10.1002/Jez.1402580313 |
0.498 |
|
| 1990 |
Downs SM. Stimulation of parthenogenesis in mouse ovarian follicles by inhibitors of inosine monophosphate dehydrogenase Biology of Reproduction. 43: 427-436. PMID 2271723 DOI: 10.1095/Biolreprod43.3.427 |
0.474 |
|
| 1990 |
Downs SM. Protein synthesis inhibitors prevent both spontaneous and hormone-dependent maturation of isolated mouse oocytes Molecular Reproduction and Development. 27: 235-243. PMID 2127675 DOI: 10.1002/Mrd.1080270309 |
0.514 |
|
| 1990 |
Fagbohun CF, Downs SM. Maturation of the mouse oocyte-cumulus cell complex: Stimulation by lectins Biology of Reproduction. 42: 413-423. PMID 1692744 DOI: 10.1095/Biolreprod42.3.413 |
0.58 |
|
| 1989 |
Downs SM. Specificity of epidermal growth factor action on maturation of the murine oocyte and cumulus oophorus in vitro Biology of Reproduction. 41: 371-379. PMID 2508778 DOI: 10.1095/Biolreprod41.2.371 |
0.352 |
|
| 1989 |
Downs SM, Daniel SAJ, Bornslaeger EA, Hoppe PC, Eppig JJ. Maintenance of meiotic arrest in mouse oocytes by purines: modulation of cAMP levels and cAMP phosphodiesterase activity Gamete Research. 23: 323-334. PMID 2476369 DOI: 10.1002/Mrd.1120230309 |
0.557 |
|
| 1988 |
Schroeder AC, Downs SM, Eppig JJ. Factors affecting the developmental capacity of mouse oocytes undergoing maturation in vitro Annals of the New York Academy of Sciences. 541: 197-204. PMID 3195905 DOI: 10.1111/J.1749-6632.1988.Tb22256.X |
0.423 |
|
| 1988 |
Eppig JJ, Downs SM. The role of purines in the maintenance of meiotic arrest in mammalian oocytes Progress in Clinical and Biological Research. 267: 103-113. PMID 2907145 |
0.332 |
|
| 1988 |
Eppig JJ, Downs SM. Gonadotropin-induced murine oocyte maturation in vivo is not associated with decreased cyclic adenosine monophosphate in the oocyte-cumulus cell complex Gamete Research. 20: 125-131. PMID 2853129 DOI: 10.1002/Mrd.1120200203 |
0.525 |
|
| 1988 |
Downs SM, Daniel SAJ, Eppig JJ. Induction of maturation in cumulus cell enclosed mouse oocytes by follicle-stimulating hormone and epidermal growth factor: Evidence for a positive stimulus of somatic cell origin Journal of Experimental Zoology. 245: 86-96. PMID 2832512 DOI: 10.1002/Jez.1402450113 |
0.545 |
|
| 1987 |
Eppig JJ, Downs SM. The effect of hypoxanthine on mouse oocyte growth and development in vitro: Maintenance of meiotic arrest and gonadotropin-induced oocyte maturation Developmental Biology. 119: 313-321. PMID 3100361 DOI: 10.1016/0012-1606(87)90037-6 |
0.526 |
|
| 1987 |
Downs SM, Eppig JJ. Induction of mouse oocyte maturation in vivo by perturbants of purine metabolism Biology of Reproduction. 36: 431-437. PMID 2883997 DOI: 10.1095/Biolreprod36.2.431 |
0.495 |
|
| 1986 |
Downs SM, Eppig JJ. The role of purines in the maintenance of meiotic arrest in mouse oocytes Tokai Journal of Experimental and Clinical Medicine. 11: 463-469. PMID 3445261 |
0.367 |
|
| 1986 |
Downs SM, Coleman DL, Eppig JJ. Maintenance of murine oocyte meiotic arrest: uptake and metabolism of hypoxanthine and adenosine by cumulus cell-enclosed and denuded oocytes. Developmental Biology. 117: 174-83. PMID 2875006 DOI: 10.1016/0012-1606(86)90359-3 |
0.436 |
|
| 1986 |
Downs SM, Schroeder AC, Eppig JJ. Developmental capacity of mouse oocytes following maintenance of meiotic arrest in vitro Gamete Research. 15: 305-316. DOI: 10.1002/Mrd.1120150404 |
0.435 |
|
| 1986 |
Downs SM, Schroeder AC, Eppig JJ. Serum maintains the fertilizability of mouse oocytes matured in vitro by preventing hardening of the zona pellucida Gamete Research. 15: 115-122. DOI: 10.1002/Mrd.1120150203 |
0.413 |
|
| 1985 |
Downs SM, Coleman DL, Ward-Bailey PF, Eppig JJ. Hypoxanthine is the principal inhibitor of murine oocyte maturation in a low molecular weight fraction of porcine follicular fluid Proceedings of the National Academy of Sciences of the United States of America. 82: 454-458. PMID 2982158 DOI: 10.1073/Pnas.82.2.454 |
0.39 |
|
| 1985 |
Downs SM, Eppig JJ. A follicular fluid component prevents gonadotropin reversal of cyclic adenosine monophosphate-dependent meiotic arrest in murine oocytes Gamete Research. 11: 83-97. DOI: 10.1002/Mrd.1120110109 |
0.519 |
|
| 1984 |
Eppig JJ, Downs SM. Chemical signals that regulate mammalian oocyte maturation Biology of Reproduction. 30: 1-11. PMID 6320914 DOI: 10.1095/Biolreprod30.1.1 |
0.552 |
|
| 1984 |
Downs SM, Eppig JJ. Cyclic adenosine monophosphate and ovarian follicular fluid act synergistically to inhibit mouse oocyte maturation Endocrinology. 114: 418-427. PMID 6197295 DOI: 10.1210/Endo-114-2-418 |
0.506 |
|
| 1983 |
Downs SM, Longo FJ. An ultrastructural study of preovulatory apical development in mouse ovanan follicles: Effects of indomethacin The Anatomical Record. 205: 159-168. PMID 6846867 DOI: 10.1002/Ar.1092050206 |
0.382 |
|
| 1983 |
Downs SM, Longo FJ. Prostaglandins and preovulatory follicular maturation in mice Journal of Experimental Zoology. 228: 99-108. PMID 6582216 DOI: 10.1002/Jez.1402280111 |
0.416 |
|
| 1982 |
Downs SM, Longo FJ. Effects of indomethacin on preovulatory follicles in immature, superovulated mice American Journal of Anatomy. 164: 265-274. PMID 7124657 DOI: 10.1002/Aja.1001640307 |
0.456 |
|
| 1982 |
Downs SM, Longo FJ. Effects of indomethacin on the ultrastructures of mouse preovulatory follicles Anatomical Record. 202. |
0.312 |
|
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