Harold W. Cook - Publications

Affiliations: 
Dalhousie University, Halifax, Nova Scotia, Canada 
Area:
Biochemistry, Cell Biology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Morash SC, Douglas D, McMaster CR, Cook HW, Byers DM. Expression of MARCKS effector domain mutants alters phospholipase D activity and cytoskeletal morphology of SK-N-MC neuroblastoma cells. Neurochemical Research. 30: 1353-64. PMID 16341931 DOI: 10.1007/S11064-005-8220-6  0.45
2005 Bailey K, Cook HW, McMaster CR. The phospholipid scramblase PLSCR1 increases UV induced apoptosis primarily through the augmentation of the intrinsic apoptotic pathway and independent of direct phosphorylation by protein kinase C delta. Biochimica Et Biophysica Acta. 1733: 199-209. PMID 15863367 DOI: 10.1016/J.Bbalip.2004.12.013  0.465
2004 Yu A, McMaster CR, Byers DM, Ridgway ND, Cook HW. Resistance to UV-induced apoptosis in Chinese-hamster ovary cells overexpressing phosphatidylserine synthases. The Biochemical Journal. 381: 609-18. PMID 15099192 DOI: 10.1042/Bj20031857  0.727
2004 Sundaram M, Cook HW, Byers DM. The MARCKS family of phospholipid binding proteins: regulation of phospholipase D and other cellular components. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 82: 191-200. PMID 15052337 DOI: 10.1139/O03-087  0.376
2003 Murphy A, Sunohara JR, Sundaram M, Ridgway ND, McMaster CR, Cook HW, Byers DM. Induction of protein kinase C substrates, Myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein (MRP), by amyloid beta-protein in mouse BV-2 microglial cells. Neuroscience Letters. 347: 9-12. PMID 12865129 DOI: 10.1016/S0304-3940(03)00648-7  0.34
2003 Yu A, McMaster CR, Byers DM, Ridgway ND, Cook HW. Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1. The Journal of Biological Chemistry. 278: 9706-14. PMID 12509439 DOI: 10.1074/Jbc.M204614200  0.736
2002 Cook HW. Chapter 7 Fatty acid desaturation and chain elongation in eukaryotes New Comprehensive Biochemistry. 36: 141-169. DOI: 10.1016/S0167-7306(02)36009-5  0.315
2001 Sunohara JR, Ridgway ND, Cook HW, Byers DM. Regulation of MARCKS and MARCKS-related protein expression in BV-2 microglial cells in response to lipopolysaccharide. Journal of Neurochemistry. 78: 664-72. PMID 11483670 DOI: 10.1046/J.1471-4159.2001.00458.X  0.354
2000 Yu A, Byers DM, Ridgway ND, McMaster CR, Cook HW. Preferential externalization of newly synthesized phosphatidylserine in apoptotic U937 cells is dependent on caspase-mediated pathways. Biochimica Et Biophysica Acta. 1487: 296-308. PMID 11018481 DOI: 10.1016/S1388-1981(00)00100-1  0.728
2000 Morash SC, Byers DM, Cook HW. Activation of phospholipase D by PKC and GTPγS in human neuroblastoma cells overexpressing MARCKS Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1487: 177-189. PMID 11018470 DOI: 10.1016/S1388-1981(00)00094-9  0.464
1999 Ridgway ND, Byers DM, Cook HW, Storey MK. Integration of phospholipid and sterol metabolism in mammalian cells. Progress in Lipid Research. 38: 337-60. PMID 10793888 DOI: 10.1016/S0163-7827(99)00007-7  0.439
1999 Zhang J, Ming LJ, Sjövall J, Cook HW, Ridgway ND, Byers DM. Progesterone metabolism in human fibroblasts is independent of P-glycoprotein levels and Niemann-Pick type C disease. The Journal of Steroid Biochemistry and Molecular Biology. 70: 123-31. PMID 10622400 DOI: 10.1016/S0960-0760(99)00107-7  0.328
1999 Douglas DN, Fink HS, Ridgway ND, Cook HW, Byers DM. Myristoylated alanine-rich C-kinase substrate is phosphorylated and translocated by a phorbol ester-insensitive and calcium-independent protein kinase C isoform in C6 glioma cell membranes. Biochimica Et Biophysica Acta. 1448: 439-49. PMID 9990296 DOI: 10.1016/S0167-4889(98)00161-X  0.392
1999 Sparrow SM, Carter JM, Ridgway ND, Cook HW, Byers DM. U18666A inhibits intracellular cholesterol transport and neurotransmitter release in human neuroblastoma cells. Neurochemical Research. 24: 69-77. PMID 9973239 DOI: 10.1023/A:1020932130753  0.415
1998 Ridgway ND, Lagace TA, Cook HW, Byers DM. Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization. The Journal of Biological Chemistry. 273: 31621-8. PMID 9813079 DOI: 10.1074/Jbc.273.47.31621  0.405
1998 Storey MK, Byers DM, Cook HW, Ridgway ND. Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol. The Biochemical Journal. 336: 247-56. PMID 9806908 DOI: 10.1042/Bj3360247  0.471
1998 Laurin DE, Byers DM, Frederick FB, Cook HW. Diacylglycerol molecular species in plasma membrane and microsomes change transiently with endothelin-1 treatment of glioma cells Prostaglandins and Other Lipid Mediators. 55: 189-207. PMID 9644111 DOI: 10.1016/S0090-6980(98)00022-7  0.382
1998 Logan HE, Byers DM, Ridgway ND, Cook HW. Phospholipase D activity is altered in X-linked adrenoleukodystrophy heterozygous carriers, but not in hemizygous patients. Biochimica Et Biophysica Acta. 1407: 7-20. PMID 9639664 DOI: 10.1016/S0925-4439(98)00021-0  0.348
1998 Morash SC, Rosé SD, Byers DM, Ridgway ND, Cook HW. Overexpression of myristoylated alanine-rich C-kinase substrate enhances activation of phospholipase D by protein kinase C in SK-N-MC human neuroblastoma cells. The Biochemical Journal. 332: 321-7. PMID 9601059 DOI: 10.1042/Bj3320321  0.47
1998 Cook HW, Ridgway ND, Byers DM. Involvement of phospholipase D and protein kinase C in phorbol ester and fatty acid stimulated turnover of phosphatidylcholine and phosphatidylethanolamine in neural cells. Biochimica Et Biophysica Acta. 1390: 103-17. PMID 9487144 DOI: 10.1016/S0005-2760(97)00162-8  0.441
1998 Ridgway ND, Badiani K, Byers DM, Cook HW. Inhibition of phosphorylation of the oxysterol binding protein by brefeldin A. Biochimica Et Biophysica Acta. 1390: 37-51. PMID 9487139 DOI: 10.1016/S0005-2760(97)00167-7  0.399
1997 Lagace TA, Byers DM, Cook HW, Ridgway ND. Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain. The Biochemical Journal. 326: 205-13. PMID 9337870 DOI: 10.1042/Bj3260205  0.422
1997 Douglas DN, Fink HS, Rosé SD, Ridgway ND, Cook HW, Byers DM. Inhibitors of actin polymerization and calmodulin binding enhance protein kinase C-induced translocation of MARCKS in C6 glioma cells. Biochimica Et Biophysica Acta. 1356: 121-30. PMID 9150270 DOI: 10.1016/S0167-4889(96)00164-4  0.374
1997 Van Iderstine SC, Byers DM, Ridgway ND, Cook HW. Phospholipase D hydrolysis of plasmalogen and diacyl ethanolamine phosphoglycerides by protein kinase C dependent and independent mechanisms. Journal of Lipid Mediators and Cell Signalling. 15: 175-92. PMID 9034963 DOI: 10.1016/S0929-7855(96)00552-4  0.429
1996 Badiani K, Byers DM, Cook HW, Ridgway ND. Effect of fumonisin B1 on phosphatidylethanolamine biosynthesis in Chinese hamster ovary cells. Biochimica Et Biophysica Acta. 1304: 190-6. PMID 8982265 DOI: 10.1016/S0005-2760(96)00119-1  0.408
1996 Cook HW, Morash SC, Rosé SD, Ridgway ND, Byers DM. Protein kinase C isoforms and growth, differentiation and phosphatidylcholine turnover in human neuroblastoma cells. Journal of Lipid Mediators and Cell Signalling. 14: 203-8. PMID 8906563 DOI: 10.1016/0929-7855(96)00526-3  0.425
1996 Mandla SG, Byers DM, Ridgway ND, Cook HW. Differential alterations of ethanolamine and choline phosphoglyceride metabolism by clofibrate and retinoic acid in human fibroblasts are not mediated by phorbol ester-sensitive protein kinase C. Lipids. 31: 747-55. PMID 8827698 DOI: 10.1007/Bf02522891  0.392
1995 Sproull SA, Morash SC, Byers DM, Palmer FBSC, Cook HW. Phorbol ester stimulation of phosphatidylcholine synthesis in four cultured neural cell lines: Correlations with expression of protein kinase C isoforms Neurochemical Research. 20: 1397-1407. PMID 8789601 DOI: 10.1007/Bf00970587  0.428
1994 Byers DM, Douglas JA, Cook HW, Palmer FB, Ridgway ND. Regulation of intracellular cholesterol metabolism is defective in lymphoblasts from Niemann-Pick type C and type D patients. Biochimica Et Biophysica Acta. 1226: 173-80. PMID 8204665 DOI: 10.1016/0925-4439(94)90026-4  0.406
1994 Xu Z, Byers DM, Palmer FBSC, Cook HW. Serine and ethanolamine incorporation into different plasmalogen pools: Subcellular analyses of phosphoglyceride synthesis in cultured glioma cells Neurochemical Research. 19: 769-775. PMID 8065535 DOI: 10.1007/Bf00967718  0.379
1994 Rosé SD, Cook HW, Palmer FB, Ridgway ND, Byers DM. Differential expression of MARCKS and other calmodulin-binding protein kinase C substrates in cultured neuroblastoma and glioma cells. Journal of Neurochemistry. 63: 2314-23. PMID 7964753 DOI: 10.1046/J.1471-4159.1994.63062314.X  0.455
1993 Byers DM, Palmer FBSC, Spence MW, Cook HW. Dissociation of phosphorylation and translocation of a myristoylated protein kinase C substrate (MARCKS protein) in C6 glioma and N1E-115 neuroblastoma Journal of Neurochemistry. 60: 1414-1421. PMID 8455032 DOI: 10.1111/J.1471-4159.1993.Tb03303.X  0.437
1993 Sidhu HS, Rastogi SA, Byers DM, Guernsey DL, Cook HW, Palmer FB, Spence MW. Regulation of low density lipoprotein receptor and 3-hydroxy-3-methyl-glutaryl-CoA reductase activities are differentially affected in Niemann-Pick type C and type D fibroblasts Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 71: 467-474. PMID 8192899 DOI: 10.1139/O93-069  0.433
1992 Byers DM, Morgan MW, Cook HW, Frederick FB, Spence MW. Niemann-Pick Type II fibroblasts exhibit impaired cholesterol esterification in response to shingomyelin hydrolysis Bba - Molecular Basis of Disease. 1138: 20-26. PMID 1737066 DOI: 10.1016/0925-4439(92)90146-E  0.405
1992 Sidhu HS, Rastogi SAR, Byers DM, Cook HW, B.St.C. Palmer F, Spence MW. Cultured fibroblasts from patients with Niemann-Pick disease type C and type D exhibit distinct defects in cholesterol esterification Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1124: 29-35. PMID 1543723 DOI: 10.1016/0005-2760(92)90122-C  0.314
1991 George TP, Cook HW, Byers DM, Palmer FB, Spence MW. Inhibition of phosphatidylcholine and phosphatidylethanolamine biosynthesis by cytochalasin B in cultured glioma cells: potential regulation of biosynthesis by Ca(2+)-dependent mechanisms. Biochimica Et Biophysica Acta. 1084: 185-93. PMID 1854804 DOI: 10.1016/0005-2760(91)90219-8  0.388
1989 George TP, Morash SC, Cook HW, Byers DM, Palmer FB, Spence MW. Phosphatidylcholine biosynthesis in cultured glioma cells: evidence for channeling of intermediates. Biochimica Et Biophysica Acta. 1004: 283-91. PMID 2758024 DOI: 10.1016/0005-2760(89)90075-1  0.445
1989 Morash SC, Cook HW, Spence MW. Lysophosphatidylcholine as an intermediate in phosphatidylcholine metabolism and glycerophosphocholine synthesis in cultured cells: an evaluation of the roles of 1-acyl- and 2-acyl-lysophosphatidylcholine. Biochimica Et Biophysica Acta. 1004: 221-229. PMID 2752020 DOI: 10.1016/0005-2760(89)90271-3  0.432
1989 Byers DM, Cook HW, Palmer FBSC, Spence MW. Cell-specific fatty acylation of proteins in cultured cells of neuronal and glial origin Neurochemical Research. 14: 503-509. PMID 2548106 DOI: 10.1007/Bf00964910  0.442
1989 Cook HW, Spence MW. Dideoxycytidine, an anti-HIV drug, selectively inhibits growth but not phosphatidylcholine metabolism in neuroblastoma and glioma cells. Neurochemical Research. 14: 279-284. PMID 2542824 DOI: 10.1007/Bf00971324  0.415
1988 Morash SC, Cook HW, Spence MW. Phosphatidylcholine metabolism in cultured cells; catabolism via glycerophosphocholine Biochimica Et Biophysica Acta. 961: 194-202. PMID 3390456 DOI: 10.1016/0005-2760(88)90114-2  0.473
1988 Cook HW, Palmer FBSC, Byers DM, Spence MW. Isolation of plasma membranes from cultured glioma cells and application to evaluation of membrane sphingomyelin turnover Analytical Biochemistry. 174: 552-560. PMID 3239757 DOI: 10.1016/0003-2697(88)90055-3  0.388
1988 Glanville TN, Spence MW, Cook HW, Palmer FBSC. Sodium channel activation does not alter lipid metabolism in cultured neuroblastoma cells. Neurochemical Research. 13: 1015-1021. PMID 2853304 DOI: 10.1007/Bf00973144  0.439
1987 Cook HW, Spence MW. Interaction of (n-3) and (n-6) fatty acids in desaturation and chain elongation of essential fatty acids in cultured glioma cells. Lipids. 22: 613-619. PMID 3669924 DOI: 10.1007/Bf02533938  0.36
1987 Cook HW, Spence MW. Studies of the modulation of essential fatty acid metabolism by fatty acids in cultured neuroblastoma and glioma cells. Biochimica Et Biophysica Acta. 918: 217-229. PMID 3105586 DOI: 10.1016/0005-2760(87)90224-4  0.395
1986 Chakravarthy BR, Spence MW, Cook HW. Turnover of phospholipid fatty acyl chains in cultured neuroblastoma cells: involvement of deacylation-reacylation and de novo synthesis in plasma membranes Biochimica Et Biophysica Acta. 879: 264-277. PMID 3778920 DOI: 10.1016/0005-2760(86)90215-8  0.4
1985 Clarke JTR, Cook HW, Spence MW. Studies on the turnover and subcellular localization of membrane gangliosides in cultured neuroblastoma cells. Neurochemical Research. 10: 427-438. PMID 4000396 DOI: 10.1007/Bf00964610  0.393
1985 Mooibroek MJ, Cook HW, Clarke JTR, Spence MW. Catabolism of Exogenous and Endogenous Sphingomyelin and Phosphatidylcholine by Homogenates and Subcellular Fractions of Cultured Neuroblastoma Cells. Effects of Anesthetics Journal of Neurochemistry. 44: 1551-1558. PMID 3989549 DOI: 10.1111/J.1471-4159.1985.Tb08794.X  0.458
1985 Chakravarthy BR, Spence MW, Clarke JTR, Cook HW. Rapid isolation of neuroblastoma plasma membranes on Percoll gradients. Characterization and lipid composition. Biochimica Et Biophysica Acta. 812: 223-233. PMID 3967013 DOI: 10.1016/0005-2736(85)90542-5  0.373
1984 Das DVM, Cook HW, Spence MW. Evidence that neutral spingomyelinase of cultured murine neuroblastoma cells is oriented externally on the plasma membrane Biochimica Et Biophysica Acta. 777: 339-342. PMID 6091759 DOI: 10.1016/0005-2736(84)90437-1  0.45
1983 D'souza CJM, Clarke JTR, Cook HW, Spence MW. Studies on the turnover of endogenous choline-containing phospholipids of cultured neuroblastoma cells Biochimica Et Biophysica Acta. 752: 467-473. PMID 6871241 DOI: 10.1016/0005-2760(83)90277-1  0.44
1983 D'Souza C, Clarke JTR, Cook HW, Spence MW. Phospholipid transfer protein-mediated incorporation and subcellular distribution of exogenous phosphatidylcholine and spingomyelin in cultured neuroblastoma cells Biochimica Et Biophysica Acta. 729: 1-8. PMID 6830780 DOI: 10.1016/0005-2736(83)90448-0  0.453
1983 Messieh S, Clarke JTR, Cook HW, Spence MW. Abnormal neutral lipase activity in acid-lipase-deficient cultured human fibroblasts. Pediatric Research. 17: 770-774. PMID 6622112 DOI: 10.1203/00006450-198309000-00018  0.311
1983 Cook HW, Clarke JTR, Spence MW. Inability of rabbit peritoneal polymorphonuclear leukocytes to synthesize arachidonic acid from linoletc acid Prostaglandins, Leukotrienes and Medicine. 10: 39-52. PMID 6402793 DOI: 10.1016/S0262-1746(83)80019-5  0.333
1982 Cook HW. Chain elongation in the formation of polyunsaturated fatty acids by brain: some properties of the microsomal system. Archives of Biochemistry and Biophysics. 214: 695-704. PMID 7092216 DOI: 10.1016/0003-9861(82)90076-5  0.315
1982 Spence MW, Wakkary J, Clarke JTR, Cook HW. Localization of neutral, magnesium-stimulated sphingomyelinase in plasma membrane of cultured neuroblastoma cells Biochimica Et Biophysica Acta. 719: 162-164. PMID 6293585 DOI: 10.1016/0304-4165(82)90321-X  0.396
1981 Cook HW. Metabolism of triacylglycerol in developing rat brain Neurochemical Research. 6: 1217-1229. PMID 7343860 DOI: 10.1007/Bf00966679  0.347
1981 Cook HW. The influence oftrans-acids on desaturation and elongation of fatty acids in developing brain Lipids. 16: 920-926. PMID 7329212 DOI: 10.1007/Bf02534998  0.329
1981 Hamilton RM, Gillespie CT, Cook HW. Relationships between levels of essential fatty acids and zinc in plasma of cystic fibrosis patients. Lipids. 16: 374-376. PMID 6789026 DOI: 10.1007/Bf02534966  0.308
1979 Cook HW. Incorporation and metabolism of the dietary trans-unsaturated fatty acid, elaidic acid, by developing rat brain. Journal of Neurochemistry. 32: 515-519. PMID 762562 DOI: 10.1111/J.1471-4159.1979.Tb00378.X  0.349
1979 Cook HW. Differential alteration of Δ9 and Δ6 desaturation of fatty acids in rat brain preparations in vitro Lipids. 14: 763-767. PMID 491860 DOI: 10.1007/Bf02533513  0.327
1978 Cook HW. Incorporation, metabolism and positional distribution of trans-unsaturated fatty acids in developing and mature brain. Comparison of elaidate and oleate administered intracerebrally Biochimica Et Biophysica Acta. 531: 245-256. PMID 737188 DOI: 10.1016/0005-2760(78)90206-0  0.354
1978 Cook HW. In vitro formation of polyunsaturated fatty acids by desaturation in rat brain: some properties of the enzymes in developing brain and comparisons with liver. Journal of Neurochemistry. 30: 1327-1334. PMID 670975 DOI: 10.1111/J.1471-4159.1978.Tb10463.X  0.311
1974 Cook HW, Spence MW. Biosynthesis of fatty acids in vitro by homogenate of developing rat brain: desaturation and chain-elongation Biochimica Et Biophysica Acta. 369: 129-141. PMID 4154108 DOI: 10.1016/0005-2760(74)90246-X  0.329
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