Dean M. Hartley - Publications

Affiliations: 
Rush University, Chicago, IL, United States 
Area:
Neuroscience Biology

15/59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pilozzi A, Yu Z, Carreras I, Cormier K, Hartley D, Rogers J, Dedeoglu A, Huang X. A Preliminary Study of Cu Exposure Effects upon Alzheimer's Amyloid Pathology. Biomolecules. 10. PMID 32155778 DOI: 10.3390/biom10030408  0.362
2016 Hamlett ED, Goetzl EJ, Ledreux A, Vasilevko V, Boger HA, LaRosa A, Clark D, Carroll SL, Carmona Iragui M, Fortea J, Mufson EJ, Sabbagh M, Mohammed AH, Hartley D, Doran E, et al. Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27755974 DOI: 10.1016/j.jalz.2016.08.012  0.329
2011 Elliott-Hunt CR, Holmes FE, Hartley DM, Perez S, Mufson EJ, Wynick D. Endogenous galanin protects mouse hippocampal neurons against amyloid toxicity in vitro via activation of galanin receptor-2. Journal of Alzheimer's Disease : Jad. 25: 455-62. PMID 21471641 DOI: 10.3233/Jad-2011-110011  0.446
2010 Jan A, Hartley DM, Lashuel HA. Preparation and characterization of toxic Abeta aggregates for structural and functional studies in Alzheimer's disease research. Nature Protocols. 5: 1186-209. PMID 20539293 DOI: 10.1038/Nprot.2010.72  0.352
2008 Hartley DM, Zhao C, Speier AC, Woodard GA, Li S, Li Z, Walz T. Transglutaminase induces protofibril-like amyloid beta-protein assemblies that are protease-resistant and inhibit long-term potentiation. The Journal of Biological Chemistry. 283: 16790-800. PMID 18397883 DOI: 10.1074/Jbc.M802215200  0.331
2007 Li S, Feig LA, Hartley DM. A brief, but repeated, swimming protocol is sufficient to overcome amyloid beta-protein inhibition of hippocampal long-term potentiation. The European Journal of Neuroscience. 26: 1289-98. PMID 17767506 DOI: 10.1111/J.1460-9568.2007.05760.X  0.3
2006 Li S, Tian X, Hartley DM, Feig LA. The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity. Current Biology : Cb. 16: 2303-13. PMID 17141611 DOI: 10.1016/J.Cub.2006.10.028  0.358
2005 Whalen BM, Selkoe DJ, Hartley DM. Small non-fibrillar assemblies of amyloid beta-protein bearing the Arctic mutation induce rapid neuritic degeneration. Neurobiology of Disease. 20: 254-66. PMID 16242634 DOI: 10.1016/J.Nbd.2005.03.007  0.34
2005 Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, El Agnaf O, Hartley DM, Selkoe DJ. Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2455-62. PMID 15758153 DOI: 10.1523/Jneurosci.4391-04.2005  0.329
2003 Kheterpal I, Lashuel HA, Hartley DM, Walz T, Lansbury PT, Wetzel R. Abeta protofibrils possess a stable core structure resistant to hydrogen exchange. Biochemistry. 42: 14092-8. PMID 14640676 DOI: 10.1021/Bi0357816  0.32
2003 Lashuel HA, Hartley DM, Petre BM, Wall JS, Simon MN, Walz T, Lansbury PT. Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores. Journal of Molecular Biology. 332: 795-808. PMID 12972252 DOI: 10.1016/S0022-2836(03)00927-6  0.356
2002 Lashuel HA, Hartley D, Petre BM, Walz T, Lansbury PT. Neurodegenerative disease: amyloid pores from pathogenic mutations. Nature. 418: 291. PMID 12124613 DOI: 10.1038/418291A  0.312
2001 Walsh DM, Hartley DM, Condron MM, Selkoe DJ, Teplow DB. In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease. The Biochemical Journal. 355: 869-77. PMID 11311152 DOI: 10.1042/Bj3550869  0.333
2000 Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. Neurons Regulate Extracellular Levels of Amyloid β-Protein via Proteolysis by Insulin-Degrading Enzyme The Journal of Neuroscience. 20: 1657-1665. DOI: 10.1523/Jneurosci.20-05-01657.2000  0.323
1999 Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, Benedek GB, Selkoe DJ, Teplow DB. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. The Journal of Biological Chemistry. 274: 25945-52. PMID 10464339 DOI: 10.1074/Jbc.274.36.25945  0.337
Low-probability matches (unlikely to be authored by this person)
2002 Lashuel HA, Hartley DM, Balakhaneh D, Aggarwal A, Teichberg S, Callaway DJ. New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease. The Journal of Biological Chemistry. 277: 42881-90. PMID 12167652 DOI: 10.1074/Jbc.M206593200  0.284
2013 Johnson KA, Minoshima S, Bohnen NI, Donohoe KJ, Foster NL, Herscovitch P, Karlawish JH, Rowe CC, Hedrick S, Pappas V, Carrillo MC, Hartley DM. Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cognitive impairment, and education. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1011-3. PMID 23753186 DOI: 10.2967/Jnumed.113.127068  0.281
2004 Goldstein LE, Hartley DM, Moir RD, Blakely EA, Chang PI, Marcus MA, Martin-Rehrmann M, Ko G, Ericsson MH, Huang X, Tanzi RE, Bush AI, Chylack LT. P1-131 (Aβ) in human lens & aqueous humor: further characterization of a novel AD biomarker Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80454-8  0.276
2004 Ye C, Walsh DM, Selkoe DJ, Hartley DM. Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation. Neuroscience Letters. 366: 320-5. PMID 15288443 DOI: 10.1016/j.neulet.2004.05.060  0.275
2013 Johnson KA, Minoshima S, Bohnen NI, Donohoe KJ, Foster NL, Herscovitch P, Karlawish JH, Rowe CC, Hedrick S, Pappas V, Carrillo MC, Hartley DM. Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cognitive impairment, and education. Amyloid Imaging Task Force of the Alzheimer’s Association and Society for Nuclear Medicine and Molecular Imaging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: e106-9. PMID 23809369 DOI: 10.1016/J.Jalz.2013.06.001  0.269
2013 Carrillo MC, Brashear HR, Logovinsky V, Ryan JM, Feldman HH, Siemers ER, Abushakra S, Hartley DM, Petersen RC, Khachaturian AS, Sperling RA. Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 123-131.e1. PMID 23411394 DOI: 10.1016/J.Jalz.2012.12.004  0.262
2002 Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 417: 74-8. PMID 11986668 DOI: 10.1038/417074A  0.26
2013 Johnson KA, Minoshima S, Bohnen NI, Donohoe KJ, Foster NL, Herscovitch P, Karlawish JH, Rowe CC, Carrillo MC, Hartley DM, Hedrick S, Pappas V, Thies WH. Appropriate use criteria for amyloid PET: a report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's Association. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 476-90. PMID 23359661 DOI: 10.2967/Jnumed.113.120618  0.252
2013 Johnson KA, Minoshima S, Bohnen NI, Donohoe KJ, Foster NL, Herscovitch P, Karlawish JH, Rowe CC, Carrillo MC, Hartley DM, Hedrick S, Pappas V, Thies WH, et al. Appropriate use criteria for amyloid PET: a report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's Association. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: e-1-16. PMID 23360977 DOI: 10.1016/J.Jalz.2013.01.002  0.251
2015 Hartley D, Blumenthal T, Carrillo M, DiPaolo G, Esralew L, Gardiner K, Granholm AC, Iqbal K, Krams M, Lemere C, Lott I, Mobley W, Ness S, Nixon R, Potter H, et al. Down syndrome and Alzheimer's disease: Common pathways, common goals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 700-9. PMID 25510383 DOI: 10.1016/J.Jalz.2014.10.007  0.241
2003 Ye CP, Selkoe DJ, Hartley DM. Protofibrils of amyloid beta-protein inhibit specific K+ currents in neocortical cultures. Neurobiology of Disease. 13: 177-90. PMID 12901832 DOI: 10.1016/S0969-9961(03)00068-8  0.233
2009 Arai JA, Li S, Hartley DM, Feig LA. Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1496-502. PMID 19193896 DOI: 10.1523/Jneurosci.5057-08.2009  0.21
1990 Hartley DM, Snodgrass SR. Folate interactions with cerebral G proteins. Neurochemical Research. 15: 681-6. PMID 2118600 DOI: 10.1007/BF00973648  0.196
2007 Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan K. Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 18754-9. PMID 18000063 DOI: 10.1073/Pnas.0704908104  0.181
2007 Dasgupta S, Roy A, Jana M, Hartley DM, Pahan K. Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Molecular Pharmacology. 72: 934-46. PMID 17625103 DOI: 10.1124/Mol.106.033787  0.175
1988 Hartley DM, Snodgrass SR, Bradshaw PA. The measurement of gamma-glutamyl hydrolase (conjugase) activity in rat brain. Neurochemical Research. 13: 147-51. PMID 3362292 DOI: 10.1007/BF00973326  0.165
2000 Fezoui Y, Hartley DM, Walsh DM, Selkoe DJ, Osterhut JJ, Teplow DB. A de novo designed α-helical peptide forms amyloid fibrils which are not neurotoxic Neurobiology of Aging. 21: 77. DOI: 10.1016/S0197-4580(00)82568-3  0.165
1999 Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, Teplow DB, Selkoe DJ. Protofibrillar Intermediates of Amyloid β-Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons The Journal of Neuroscience. 19: 8876-8884. DOI: 10.1523/JNEUROSCI.19-20-08876.1999  0.161
2000 Fezoui Y, Hartley DM, Harper JD, Khurana R, Walsh DM, Condron MM, Fink AL, Teplow DB. An improved method of preparing the amyloid β-protein for fibrillogenesis and neurotoxicity experiments Neurobiology of Aging. 21: 77. DOI: 10.1016/S0197-4580(00)82569-5  0.16
2017 Grill JD, Apostolova LG, Bullain S, Burns JM, Cox CG, Dick M, Hartley D, Kawas C, Kremen S, Lingler J, Lopez OL, Mapstone M, Pierce A, Rabinovici G, Roberts JS, et al. Communicating mild cognitive impairment diagnoses with and without amyloid imaging. Alzheimer's Research & Therapy. 9: 35. PMID 28472970 DOI: 10.1186/S13195-017-0261-Y  0.151
2000 Fezoui Y, Hartley DM, Walsh DM, Selkoe DJ, Osterhout JJ, Teplow DB. A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils. Nature Structural Biology. 7: 1095-9. PMID 11101888 DOI: 10.1038/81937  0.145
2006 Li S, Tian X, Hartley DM, Feig LA. Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1721-9. PMID 16467520 DOI: 10.1523/Jneurosci.3990-05.2006  0.13
1990 Hartley DM, Monyer H, Colamarino SA, Choi DW. 7-Chlorokynurenate Blocks NMDA Receptor-Mediated Neurotoxicity in Murine Cortical Culture. The European Journal of Neuroscience. 2: 291-295. PMID 12106035 DOI: 10.1111/J.1460-9568.1990.Tb00420.X  0.126
1990 Klingman JG, Hartley DM, Choi DW. Automated determination of excitatory amino acid neurotoxicity in cortical culture Journal of Neuroscience Methods. 31: 47-51. PMID 2308381 DOI: 10.1016/0165-0270(90)90008-4  0.121
1992 Monyer H, Giffard RG, Hartley DM, Dugan LL, Goldberg MP, Choi DW. Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin. Neuron. 8: 967-73. PMID 1350203 DOI: 10.1016/0896-6273(92)90211-U  0.117
2000 Fezoui Y, Hartley DM, Harper JD, Khurana R, Walsh DM, Condron MM, Selkoe DJ, Lansbury PT, Fink AL, Teplow DB. An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 7: 166-78. PMID 11019857 DOI: 10.3109/13506120009146831  0.085
2021 Rehm HL, Page AJH, Smith L, Adams JB, Alterovitz G, Babb LJ, Barkley MP, Baudis M, Beauvais MJS, Beck T, Beckmann JS, Beltran S, Bernick D, Bernier A, Bonfield JK, ... ... Hartley DM, et al. GA4GH: International policies and standards for data sharing across genomic research and healthcare. Cell Genomics. 1. PMID 35072136 DOI: 10.1016/j.xgen.2021.100029  0.084
2021 Loureiro LO, Howe JL, Reuter MS, Iaboni A, Calli K, Roshandel D, Pritišanac I, Moses A, Forman-Kay JD, Trost B, Zarrei M, Rennie O, Lau LYS, Marshall CR, Srivastava S, ... ... Hartley D, et al. A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder. Npj Genomic Medicine. 6: 91. PMID 34737294 DOI: 10.1038/s41525-021-00254-0  0.077
2006 Bandyopadhyay S, Hartley DM, Cahill CM, Lahiri DK, Chattopadhyay N, Rogers JT. Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase. Journal of Neuroscience Research. 84: 106-18. PMID 16724341 DOI: 10.1002/Jnr.20864  0.073
2012 Youmans KL, Tai LM, Kanekiyo T, Stine WB, Michon SC, Nwabuisi-Heath E, Manelli AM, Fu Y, Riordan S, Eimer WA, Binder L, Bu G, Yu C, Hartley DM, LaDu MJ. Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. Molecular Neurodegeneration. 7: 8. PMID 22423893 DOI: 10.1186/1750-1326-7-8  0.073
1990 Monyer H, Hartley DM, Choi DW. 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures. Neuron. 5: 121-6. PMID 2166544 DOI: 10.1016/0896-6273(90)90302-V  0.073
1990 Weiss J, Hartley D, Koh J, Choi D. The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity Science. 247: 1474-1477. PMID 2157282 DOI: 10.1126/Science.2157282  0.07
2022 Trost B, Thiruvahindrapuram B, Chan AJS, Engchuan W, Higginbotham EJ, Howe JL, Loureiro LO, Reuter MS, Roshandel D, Whitney J, Zarrei M, Bookman M, Somerville C, Shaath R, Abdi M, ... ... Hartley DM, et al. Genomic architecture of autism from comprehensive whole-genome sequence annotation. Cell. 185: 4409-4427.e18. PMID 36368308 DOI: 10.1016/j.cell.2022.10.009  0.065
1987 Hartley DM. Glucose-6-phosphate dehydrogenase activity in the freshwater bivalve, Corbicula manilensis Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 88: 471-474. DOI: 10.1016/0305-0491(87)90329-4  0.063
2016 Alphs L, Brashear HR, Chappell P, Conwell Y, Dubrava S, Khin NA, Kozauer N, Hartley DM, Miller DS, Schindler RJ, Siemers ER, Stewart M, Yaffe K. Considerations for the assessment of suicidal ideation and behavior in older adults with cognitive decline and dementia Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2: 48-59. DOI: 10.1016/j.trci.2016.02.001  0.062
2016 Chappell P, Dubrava S, Stewart M, Hartley DM, Alphs L, Brashear HR, Conwell Y, Miller D, Schindler RJ, Siemers ER, Yaffe K. Suicidal ideation and behavior assessment in dementia studies: An Internet survey Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2: 60-68. DOI: 10.1016/j.trci.2016.02.002  0.057
2020 Trost B, Engchuan W, Nguyen CM, Thiruvahindrapuram B, Dolzhenko E, Backstrom I, Mirceta M, Mojarad BA, Yin Y, Dov A, Chandrakumar I, Prasolava T, Shum N, Hamdan O, Pellecchia G, ... ... Hartley D, et al. Genome-wide detection of tandem DNA repeats that are expanded in autism. Nature. PMID 32717741 DOI: 10.1038/S41586-020-2579-Z  0.055
2016 Chappell P, Dubrava S, Stewart M, Hartley DM, Alphs L, Brashear HR, Conwell Y, Miller D, Schindler RJ, Siemers ER, Yaffe K. Suicidal ideation and behavior assessment in dementia studies: An Internet survey. Alzheimer's & Dementia (New York, N. Y.). 2: 60-68. PMID 29067294 DOI: 10.1016/J.Trci.2016.02.002  0.04
2021 Rehm HL, Page AJ, Smith L, Adams JB, Alterovitz G, Babb LJ, Barkley MP, Baudis M, Beauvais MJ, Beck T, Beckmann JS, Beltran S, Bernick D, Bernier A, Bonfield JK, ... ... Hartley DM, et al. GA4GH: International policies and standards for data sharing across genomic research and healthcare Cell Genomics. 1: 100029. DOI: 10.1016/j.xgen.2021.100029  0.034
2017 Stutzmann GE, Hartley D. [F4–06–01]: UPDATE OF THE CALCIUM HYPOTHESIS: A FRAMEWORK FOR INTEGRATING NEW EVIDENCE INTO A COMPREHENSIVE THEORY OF PATHOGENESIS Alzheimer's & Dementia. 13. DOI: 10.1016/j.jalz.2017.07.394  0.027
2016 Alphs L, Brashear HR, Chappell P, Conwell Y, Dubrava S, Khin NA, Kozauer N, Hartley DM, Miller DS, Schindler RJ, Siemers ER, Stewart M, Yaffe K. Considerations for the assessment of suicidal ideation and behavior in older adults with cognitive decline and dementia. Alzheimer's & Dementia (New York, N. Y.). 2: 48-59. PMID 29067293 DOI: 10.1016/J.Trci.2016.02.001  0.024
2008 Hartley DM, Li S. P1‐123: Brief swimming rescues amyloid‐beta protein inhibition of long‐term potentiation Alzheimer's & Dementia. 4. DOI: 10.1016/j.jalz.2008.05.710  0.01
2003 Walsh D, Hartley D, Selkoe D. The Many Faces of Aβ: Structures and Activity Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 3: 277-291. DOI: 10.2174/1568013033483311  0.01
1983 Hartley DM, Johnston JB. Use of the freshwater clam Corbicula manilensis as a monitor for organochlorine pesticides. Bulletin of Environmental Contamination and Toxicology. 31: 33-40. PMID 6882939 DOI: 10.1007/BF01608763  0.01
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