Eduardo A. Nillni - Publications

Affiliations: 
Brown University, Providence, RI 
Area:
Cell Biology, Biochemistry, Physiology Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cakir I, Nillni EA. Endoplasmic Reticulum Stress, the Hypothalamus, and Energy Balance. Trends in Endocrinology and Metabolism: Tem. PMID 30691778 DOI: 10.1016/j.tem.2019.01.002  0.72
2015 Faulkner LD, Dowling AR, Stuart RC, Nillni EA, Hill JW. Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity. Endocrinology. 156: 1372-85. PMID 25590244 DOI: 10.1210/En.2014-1788  0.48
2015 Cyr NE, Steger JS, Toorie AM, Yang JZ, Stuart R, Nillni EA. Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats. Endocrinology. 156: 961-74. PMID 25549049 DOI: 10.1210/en.2014-1970  0.48
2014 Cyr NE, Steger JS, Toorie AM, Yang JZ, Stuart R, Nillni EA. Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats. Endocrinology. 155: 2423-35. PMID 24773342 DOI: 10.1210/en.2013-1998  0.48
2014 Mercer AJ, Stuart RC, Attard CA, Otero-Corchon V, Nillni EA, Low MJ. Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice. American Journal of Physiology. Endocrinology and Metabolism. 306: E904-15. PMID 24518677 DOI: 10.1152/Ajpendo.00540.2013  0.48
2013 Nie Y, Ferrini MG, Liu Y, Anghel A, Espinosa EV, Stuart RC, Lutfy K, Nillni EA, Friedman TC. Morphine treatment selectively regulates expression of rat pituitary POMC and the prohormone convertases PC1/3 and PC2. Peptides. 47: 99-109. PMID 23891651 DOI: 10.1016/j.peptides.2013.07.006  0.48
2013 Cakir I, Cyr NE, Perello M, Litvinov BP, Romero A, Stuart RC, Nillni EA. Obesity induces hypothalamic endoplasmic reticulum stress and impairs proopiomelanocortin (POMC) post-translational processing. The Journal of Biological Chemistry. 288: 17675-88. PMID 23640886 DOI: 10.1074/Jbc.M113.475343  0.48
2013 Cyr NE, Toorie AM, Steger JS, Sochat MM, Hyner S, Perello M, Stuart R, Nillni EA. Mechanisms by which the orexigen NPY regulates anorexigenic α-MSH and TRH. American Journal of Physiology. Endocrinology and Metabolism. 304: E640-50. PMID 23321476 DOI: 10.1152/Ajpendo.00448.2012  0.48
2013 Newton AJ, Hess S, Paeger L, Vogt MC, Fleming Lascano J, Nillni EA, Brüning JC, Kloppenburg P, Xu AW. AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice. Endocrinology. 154: 172-83. PMID 23161869 DOI: 10.1210/en.2012-1643  0.48
2013 Chiappini F, Ramadoss P, Vella KR, Cunha LL, Ye FD, Stuart RC, Nillni EA, Hollenberg AN. Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus. Molecular and Cellular Endocrinology. 365: 84-94. PMID 23000398 DOI: 10.1016/j.mce.2012.09.006  0.48
2012 Cabral A, Valdivia S, Reynaldo M, Cyr NE, Nillni EA, Perello M. Short-term cold exposure activates TRH neurons exclusively in the hypothalamic paraventricular nucleus and raphe pallidus. Neuroscience Letters. 518: 86-91. PMID 22580206 DOI: 10.1016/J.Neulet.2012.04.059  0.48
2012 Cyr NE, Stuart RC, Zhu X, Steiner DF, Nillni EA. Biosynthesis of proTRH-derived peptides in prohormone convertase 1 and 2 knockout mice. Peptides. 35: 42-8. PMID 22421509 DOI: 10.1016/J.Peptides.2012.02.024  0.48
2011 Perello M, Çakir I, Cyr NE, Romero A, Stuart RC, Chiappini F, Hollenberg AN, Nillni EA. Maintenance of the thyroid access during diet-induced obesity in rodents is controlled at the central level (American Journal of Physiology - Endocrinology and Metabolism (2010) 299, DOI:10.1152/ajpendo.00448.2010) American Journal of Physiology - Endocrinology and Metabolism. 300: E422. DOI: 10.1152/Ajpendo.Zh1-6178-Corr.2011  0.48
2010 Cantuti-Castelvetri I, Hernandez LF, Keller-McGandy CE, Kett LR, Landy A, Hollingsworth ZR, Saka E, Crittenden JR, Nillni EA, Young AB, Standaert DG, Graybiel AM. Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats. Plos One. 5: e13861. PMID 21085660 DOI: 10.1371/Journal.Pone.0013861  0.48
2010 Perello M, Cakir I, Cyr NE, Romero A, Stuart RC, Chiappini F, Hollenberg AN, Nillni EA. Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level. American Journal of Physiology. Endocrinology and Metabolism. 299: E976-89. PMID 20858755 DOI: 10.1152/Ajpendo.00448.2010  0.48
2010 Ramadori G, Fujikawa T, Fukuda M, Anderson J, Morgan DA, Mostoslavsky R, Stuart RC, Perello M, Vianna CR, Nillni EA, Rahmouni K, Coppari R. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metabolism. 12: 78-87. PMID 20620997 DOI: 10.1016/J.Cmet.2010.05.010  0.48
2010 Bousquet-Moore D, Prohaska JR, Nillni EA, Czyzyk T, Wetsel WC, Mains RE, Eipper BA. Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. Neurobiology of Disease. 37: 130-40. PMID 19815072 DOI: 10.1016/J.Nbd.2009.09.016  0.48
2009 Cakir I, Perello M, Lansari O, Messier NJ, Vaslet CA, Nillni EA. Hypothalamic Sirt1 regulates food intake in a rodent model system. Plos One. 4: e8322. PMID 20020036 DOI: 10.1371/Journal.Pone.0008322  0.48
2009 Bousquet-Moore D, Ma XM, Nillni EA, Czyzyk TA, Pintar JE, Eipper BA, Mains RE. Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper. Endocrinology. 150: 1739-47. PMID 19022883 DOI: 10.1210/en.2008-1202  0.48
2008 Romero A, Cakir I, Vaslet CA, Stuart RC, Lansari O, Lucero HA, Nillni EA. Role of a pro-sequence in the secretory pathway of prothyrotropin-releasing hormone. The Journal of Biological Chemistry. 283: 31438-48. PMID 18779326 DOI: 10.1074/jbc.M803413200  0.48
2008 Perello M, Stuart R, Nillni EA. Prothyrotropin-releasing hormone targets its processing products to different vesicles of the secretory pathway. The Journal of Biological Chemistry. 283: 19936-47. PMID 18474603 DOI: 10.1074/Jbc.M800732200  0.48
2007 Perello M, Stuart RC, Vaslet CA, Nillni EA. Cold exposure increases the biosynthesis and proteolytic processing of prothyrotropin-releasing hormone in the hypothalamic paraventricular nucleus via beta-adrenoreceptors. Endocrinology. 148: 4952-64. PMID 17584968 DOI: 10.1210/En.2007-0522  0.48
2007 Perello M, Nillni EA. The biosynthesis and processing of neuropeptides: lessons from prothyrotropin releasing hormone (proTRH). Frontiers in Bioscience : a Journal and Virtual Library. 12: 3554-65. PMID 17485321 DOI: 10.2741/2334  0.48
2007 Mulcahy LR, Nillni EA. Discovery of new peptides from old prohormones: insights for energy balance and beyond. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3545-53. PMID 17485320  1
2007 Goldstein J, Perello M, Nillni EA. PreproThyrotropin-releasing hormone 178-199 affects tyrosine hydroxylase biosynthesis in hypothalamic neurons: a possible role for pituitary prolactin regulation. Journal of Molecular Neuroscience : Mn. 31: 69-82. PMID 17416971 DOI: 10.1007/Bf02686119  0.48
2007 Enriori PJ, Evans AE, Sinnayah P, Jobst EE, Tonelli-Lemos L, Billes SK, Glavas MM, Grayson BE, Perello M, Nillni EA, Grove KL, Cowley MA. Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. Cell Metabolism. 5: 181-94. PMID 17339026 DOI: 10.1016/J.Cmet.2007.02.004  0.48
2007 Perello M, Stuart RC, Nillni EA. Differential effects of fasting and leptin on proopiomelanocortin peptides in the arcuate nucleus and in the nucleus of the solitary tract. American Journal of Physiology. Endocrinology and Metabolism. 292: E1348-57. PMID 17227963 DOI: 10.1152/Ajpendo.00466.2006  0.48
2007 Voss-Andreae A, Murphy JG, Ellacott KL, Stuart RC, Nillni EA, Cone RD, Fan W. Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Endocrinology. 148: 1550-60. PMID 17194736 DOI: 10.1210/En.2006-1389  0.48
2006 Perello M, Stuart RC, Nillni EA. The role of intracerebroventricular administration of leptin in the stimulation of prothyrotropin releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology. 147: 3296-306. PMID 16627588 DOI: 10.1210/En.2005-1533  0.48
2006 Perello M, Friedman T, Paez-Espinosa V, Shen X, Stuart RC, Nillni EA. Thyroid hormones selectively regulate the posttranslational processing of prothyrotropin-releasing hormone in the paraventricular nucleus of the hypothalamus. Endocrinology. 147: 2705-16. PMID 16497799 DOI: 10.1210/En.2005-1609  0.48
2006 Mulcahy LR, Barker AJ, Nillni EA. Disruption of disulfide bond formation alters the trafficking of prothyrotropin releasing hormone (proTRH)-derived peptides. Regulatory Peptides. 133: 123-33. PMID 16257458 DOI: 10.1016/j.regpep.2005.09.027  1
2005 Mulcahy LR, Vaslet CA, Nillni EA. Prohormone-convertase 1 processing enhances post-Golgi sorting of prothyrotropin-releasing hormone-derived peptides. The Journal of Biological Chemistry. 280: 39818-26. PMID 16204236 DOI: 10.1074/jbc.M507193200  0.48
2004 Sanchez VC, Goldstein J, Stuart RC, Hovanesian V, Huo L, Munzberg H, Friedman TC, Bjorbaek C, Nillni EA. Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin-releasing hormone. The Journal of Clinical Investigation. 114: 357-69. PMID 15286802 DOI: 10.1172/JCI21620  0.48
2004 Guo L, Münzberg H, Stuart RC, Nillni EA, Bjørbaek C. N-acetylation of hypothalamic alpha-melanocyte-stimulating hormone and regulation by leptin. Proceedings of the National Academy of Sciences of the United States of America. 101: 11797-802. PMID 15280541 DOI: 10.1073/pnas.0403165101  0.48
2004 Posner SF, Vaslet CA, Jurofcik M, Lee A, Seidah NG, Nillni EA. Stepwise posttranslational processing of progrowth hormone-releasing hormone (proGHRH) polypeptide by furin and PC1. Endocrine. 23: 199-213. PMID 15146101 DOI: 10.1385/ENDO:23:2-3:199  0.48
2004 Jing E, Nillni EA, Sanchez VC, Stuart RC, Good DJ. Deletion of the Nhlh2 transcription factor decreases the levels of the anorexigenic peptides alpha melanocyte-stimulating hormone and thyrotropin-releasing hormone and implicates prohormone convertases I and II in obesity. Endocrinology. 145: 1503-13. PMID 14701669 DOI: 10.1210/en.2003-0834  0.48
2003 Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37: 649-61. PMID 12597862 DOI: 10.1016/S0896-6273(03)00063-1  0.48
2002 Nillni EA, Xie W, Mulcahy L, Sanchez VC, Wetsel WC. Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice. The Journal of Biological Chemistry. 277: 48587-95. PMID 12270926 DOI: 10.1074/Jbc.M206702200  0.48
2001 Nillni EA, Aird F, Seidah NG, Todd RB, Koenig JI. PreproTRH(178-199) and two novel peptides (pFQ7 and pSE14) derived from its processing, which are produced in the paraventricular nucleus of the rat hypothalamus, are regulated during suckling. Endocrinology. 142: 896-906. PMID 11159863 DOI: 10.1210/Endo.142.2.7954  0.48
2001 Harris M, Aschkenasi C, Elias CF, Chandrankunnel A, Nillni EA, Bjøorbaek C, Elmquist JK, Flier JS, Hollenberg AN. Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling. The Journal of Clinical Investigation. 107: 111-20. PMID 11134186 DOI: 10.1172/JCI10741  0.48
2000 Nillni EA, Vaslet C, Harris M, Hollenberg A, Bjørbak C, Flier JS. Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways. The Journal of Biological Chemistry. 275: 36124-33. PMID 10967095 DOI: 10.1074/jbc.M003549200  0.48
1998 Bruhn TO, Huang SS, Vaslet C, Nillni EA. Glucocorticoids modulate the biosynthesis and processing of prothyrotropin releasing-hormone (proTRH). Endocrine. 9: 143-52. PMID 9867248 DOI: 10.1385/ENDO:9:2:143  0.48
1997 Schaner P, Todd RB, Seidah NG, Nillni EA. Processing of prothyrotropin-releasing hormone by the family of prohormone convertases Journal of Biological Chemistry. 272: 19958-19968. PMID 9242664 DOI: 10.1074/jbc.272.32.19958  0.48
Show low-probability matches.