Howard D. Beall - Publications

Affiliations: 
University of Montana, Missoula, MT 
Area:
Toxicology, Pharmaceutical Chemistry

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Weaver MJ, Stump S, Campbell MJ, Backos DS, Li C, Reigan P, Adams E, Beall HD, Natale NR. 10-N-heterocylic aryl-isoxazole-amides (AIMs) have robust anti-tumor activity against breast and brain cancer cell lines and useful fluorescence properties. Bioorganic & Medicinal Chemistry. 28: 115781. PMID 33038788 DOI: 10.1016/j.bmc.2020.115781  0.52
2018 Stump S, Mou TC, Sprang SR, Natale NR, Beall HD. Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene. Plos One. 13: e0205584. PMID 30312328 DOI: 10.1371/Journal.Pone.0205584  0.52
2015 Weaver MJ, Kearns AK, Stump S, Li C, Gajewski MP, Rider KC, Backos DS, Reigan PR, Beall HD, Natale NR. AIMing towards improved antitumor efficacy. Bioorganic & Medicinal Chemistry Letters. 25: 1765-70. PMID 25782743 DOI: 10.1016/J.Bmcl.2015.02.063  0.52
2014 Yilmaz A, Mohamed N, Patterson KA, Tang Y, Shilo K, Villalona-Calero MA, Davis ME, Zhou X, Frankel W, Otterson GA, Beall HD, Zhao W. Increased NQO1 but not c-MET and survivin expression in non-small cell lung carcinoma with KRAS mutations. International Journal of Environmental Research and Public Health. 11: 9491-502. PMID 25222473 DOI: 10.3390/Ijerph110909491  0.52
2014 Duncan NS, Beall HD, Kearns AK, Li C, Natale NR. Ethyl 3-(9-chloro-10-oxo-9,10-di-hydro-anthracen-9-yl)-5-methyl-isoxazole-4-carboxyl-ate. Acta Crystallographica. Section E, Structure Reports Online. 70: o315-6. PMID 24765016 DOI: 10.1107/S1600536814003080  0.52
2013 Newsome JJ, Hassani M, Swann E, Bibby JM, Beall HD, Moody CJ. Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1. Bioorganic & Medicinal Chemistry. 21: 2999-3009. PMID 23635904 DOI: 10.1016/J.Bmc.2013.03.071  0.52
2013 Keyari CM, Kearns AK, Duncan NS, Eickholt EA, Abbott G, Beall HD, Diaz P. Synthesis of new quinolinequinone derivatives and preliminary exploration of their cytotoxic properties. Journal of Medicinal Chemistry. 56: 3806-19. PMID 23574193 DOI: 10.1021/Jm301689X  0.52
2012 Mirzaei YR, Weaver MJ, Steiger SA, Kearns AK, Gajewski MP, Rider KC, Beall HD, Natale NR. Improved synthesis of 3-aryl isoxazoles containing fused aromatic rings. Tetrahedron. 68: 10360-10364. PMID 23526841 DOI: 10.1016/J.Tet.2012.09.084  0.52
2012 Kearns AK, Gajewski MP, Natale NR, Beall HD. Abstract 1767: Anthracenyl isoxazole amides (AIMs) as novel agents for brain tumors Cancer Research. 72: 1767-1767. DOI: 10.1158/1538-7445.Am2012-1767  0.52
2010 Cai W, Hassani M, Karki R, Walter ED, Koelsch KH, Seradj H, Lineswala JP, Mirzaei H, York JS, Olang F, Sedighi M, Lucas JS, Eads TJ, Rose AS, Charkhzarrin S, ... ... Beall HD, et al. Synthesis, metabolism and in vitro cytotoxicity studies on novel lavendamycin antitumor agents. Bioorganic & Medicinal Chemistry. 18: 1899-909. PMID 20149966 DOI: 10.1016/J.Bmc.2010.01.037  0.52
2009 Gajewski MP, Beall H, Schnieder M, Stranahan SM, Mosher MD, Rider KC, Natale NR. Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity. Bioorganic & Medicinal Chemistry Letters. 19: 4067-9. PMID 19560922 DOI: 10.1016/J.Bmcl.2009.06.019  0.52
2008 Hassani M, Cai W, Koelsch KH, Holley DC, Rose AS, Olang F, Lineswala JP, Holloway WG, Gerdes JM, Behforouz M, Beall HD. Lavendamycin antitumor agents: structure-based design, synthesis, and NAD(P)H:quinone oxidoreductase 1 (NQO1) model validation with molecular docking and biological studies. Journal of Medicinal Chemistry. 51: 3104-15. PMID 18457384 DOI: 10.1021/Jm701066A  0.52
2007 Newsome JJ, Colucci MA, Hassani M, Beall HD, Moody CJ. Benzimidazole- and benzothiazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1. Organic & Biomolecular Chemistry. 5: 3665-73. PMID 17971996 DOI: 10.1039/B713044A  0.52
2007 Newsome JJ, Swann E, Hassani M, Bray KC, Slawin AM, Beall HD, Moody CJ. Indolequinone antitumour agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase. Organic & Biomolecular Chemistry. 5: 1629-40. PMID 17571194 DOI: 10.1039/B703370B  0.52
2007 He W, Greenwell RJ, Brooks DM, Calderón-Garcidueñas L, Beall HD, Coffin JD. Arsenic exposure in pregnant mice disrupts placental vasculogenesis and causes spontaneous abortion. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 244-53. PMID 17569693 DOI: 10.1093/Toxsci/Kfm162  0.52
2007 Pereira FE, Coffin JD, Beall HD. Activation of protein kinase C and disruption of endothelial monolayer integrity by sodium arsenite--Potential mechanism in the development of atherosclerosis. Toxicology and Applied Pharmacology. 220: 164-77. PMID 17306850 DOI: 10.1016/J.Taap.2006.12.035  0.52
2007 Beall HD, Coffin JD. Toxicology and the endothelium Endothelial Biomedicine. 527-535. DOI: 10.1017/CBO9780511546198.060  0.52
2006 Bunderson M, Pereira F, Schneider MC, Shaw PK, Coffin JD, Beall HD. Manganese enhances peroxynitrite and leukotriene E4 formation in bovine aortic endothelial cells exposed to arsenic. Cardiovascular Toxicology. 6: 15-23. PMID 16845179 DOI: 10.1385/Ct:6:1:15  0.52
2005 Hassani M, Cai W, Holley DC, Lineswala JP, Maharjan BR, Ebrahimian GR, Seradj H, Stocksdale MG, Mohammadi F, Marvin CC, Gerdes JM, Beall HD, Behforouz M. Novel lavendamycin analogues as antitumor agents: synthesis, in vitro cytotoxicity, structure-metabolism, and computational molecular modeling studies with NAD(P)H:quinone oxidoreductase 1. Journal of Medicinal Chemistry. 48: 7733-49. PMID 16302813 DOI: 10.1021/Jm050758Z  0.52
2004 Bunderson M, Brooks DM, Walker DL, Rosenfeld ME, Coffin JD, Beall HD. Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis. Toxicology and Applied Pharmacology. 201: 32-9. PMID 15519606 DOI: 10.1016/J.Taap.2004.04.008  0.52
2004 Fryatt T, Pettersson HI, Gardipee WT, Bray KC, Green SJ, Slawin AM, Beall HD, Moody CJ. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1). Bioorganic & Medicinal Chemistry. 12: 1667-87. PMID 15028260 DOI: 10.1016/J.Bmc.2004.01.021  0.52
2002 Whatmore JL, Swann E, Barraja P, Newsome JJ, Bunderson M, Beall HD, Tooke JE, Moody CJ. Comparative study of isoflavone, quinoxaline and oxindole families of anti-angiogenic agents. Angiogenesis. 5: 45-51. PMID 12549859 DOI: 10.1023/A:1021528628524  0.52
2002 Bunderson M, Coffin JD, Beall HD. Arsenic induces peroxynitrite generation and cyclooxygenase-2 protein expression in aortic endothelial cells: possible role in atherosclerosis. Toxicology and Applied Pharmacology. 184: 11-8. PMID 12392964 DOI: 10.1006/Taap.2002.9492  0.52
2002 Beall HD, Sloan KB. Topical delivery of 5-fluorouracil (5-FU) by 1,3-bisalkylcarbonyl-5-FU prodrugs. International Journal of Pharmaceutics. 231: 43-9. PMID 11719012 DOI: 10.1016/S0378-5173(01)00869-9  0.52
2001 Swann E, Barraja P, Oberlander AM, Gardipee WT, Hudnott AR, Beall HD, Moody CJ. Indolequinone antitumor agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase. Part 2. Journal of Medicinal Chemistry. 44: 3311-9. PMID 11563930 DOI: 10.1021/Jm010884C  0.52
2001 Beall HD, Sloan KB. Topical delivery of 5-fluorouracil (5-Fu) by 3-alkylcarbonyl-5-Fu prodrugs. International Journal of Pharmaceutics. 217: 127-37. PMID 11292549 DOI: 10.1016/S0378-5173(01)00609-3  0.52
2000 Ross D, Kepa JK, Winski SL, Beall HD, Anwar A, Siegel D. NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms. Chemico-Biological Interactions. 129: 77-97. PMID 11154736 DOI: 10.1016/S0009-2797(00)00199-X  0.52
2000 Beall HD, Winski SI. Mechanisms of action of quinone-containing alkylating agents. I: NQO1-directed drug development. Frontiers in Bioscience : a Journal and Virtual Library. 5: D639-48. PMID 10877993 DOI: 10.2741/Beall  0.52
1999 Fryatt T, Goroski DT, Nilson ZD, Moody CJ, Beall HD. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1). Bioorganic & Medicinal Chemistry Letters. 9: 2195-8. PMID 10465544 DOI: 10.1016/S0960-894X(99)00369-8  0.52
1998 Beall HD, Hudnott AR, Winski S, Siegel D, Swann E, Ross D, Moody CJ. Indolequinone antitumor agents: relationship between quinone structure and rate of metabolism by recombinant human NQO1. Bioorganic & Medicinal Chemistry Letters. 8: 545-8. PMID 9871615 DOI: 10.1016/S0960-894X(98)00069-9  0.52
1998 Beall HD, Winski S, Swann E, Hudnott AR, Cotterill AS, O'Sullivan N, Green SJ, Bien R, Siegel D, Ross D, Moody CJ. Indolequinone antitumor agents: correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity. Journal of Medicinal Chemistry. 41: 4755-66. PMID 9822546 DOI: 10.1021/Jm980328R  0.52
1998 Sloan KB, Beall HD, Taylor HE, Getz JJ, Villaneuva R, Nipper R, Smith K. Transdermal delivery of theophylline from alcohol vehicles International Journal of Pharmaceutics. 171: 185-193. DOI: 10.1016/S0378-5173(98)00190-2  0.52
1997 Fish DN, Beall HD, Goodwin SD, Fox JL. Stability of sumatriptan succinate in extemporaneously prepared oral liquids. American Journal of Health-System Pharmacy : Ajhp : Official Journal of the American Society of Health-System Pharmacists. 54: 1619-22. PMID 9248606 DOI: 10.1093/ajhp/54.14.1619  0.52
1997 Traver RD, Siegel D, Beall HD, Phillips RM, Gibson NW, Franklin WA, Ross D. Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase). British Journal of Cancer. 75: 69-75. PMID 9000600 DOI: 10.1038/bjc.1997.11  0.52
1997 Patrick AI, Beall HD, Gilroy P, Sloan KB. Effect of vehicles on topical delivery of 5-fluorouracil (5FU) by 1-acyl-5FU prodrugs International Journal of Pharmaceutics. 154: 39-48. DOI: 10.1016/S0378-5173(97)00108-7  0.52
1996 Beall HD, Liu Y, Siegel D, Bolton EM, Gibson NW, Ross D. Role of NAD(P)H:quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin. Biochemical Pharmacology. 51: 645-52. PMID 8615901 DOI: 10.1016/S0006-2952(95)00223-5  0.52
1996 Beall HD, Sloan KB. Transdermal delivery of 5-fluorouracil (5-FU) by 1-alkylcarbonyl-5-FU prodrugs International Journal of Pharmaceutics. 129: 203-210. DOI: 10.1016/0378-5173(95)04327-6  0.52
1995 Peterson DM, Fisher J, Beall HD, Ross D. Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNA. Cancer Letters. 90: 133-8. PMID 7736448 DOI: 10.1016/0304-3835(95)03694-R  0.52
1993 Prakash AS, Beall H, Ross D, Gibson NW. Sequence-selective alkylation and cross-linking induced by mitomycin C upon activation by DT-diaphorase. Biochemistry. 32: 5518-25. PMID 8504072 DOI: 10.1021/Bi00072A005  0.52
1993 Ross D, Siegel D, Beall H, Prakash AS, Mulcahy RT, Gibson NW. DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C. Cancer Metastasis Reviews. 12: 83-101. PMID 8375023 DOI: 10.1007/BF00689803  0.52
1993 Beall HD, Prankerd RJ, Todaro LJ, Sloan KB. Structure of 3-acetyl-5-fluorouracil (5-FU): implication for its rearrangements during hydrolysis and upon heating. Pharmaceutical Research. 10: 905-12. PMID 8321861 DOI: 10.1023/A:1018925614514  0.52
1993 Beall HD, Getz JJ, Sloan KB. The estimation of relative water solubility for prodrugs that are unstable in water International Journal of Pharmaceutics. 93: 37-47. DOI: 10.1016/0378-5173(93)90162-9  0.52
1993 Sloan KB, Getz JJ, Beall HD, Prankerd RJ. Transdermal delivery of 5-fluorouracil (5-FU) through hairless mouse skin by 1-alkylaminocarbonyl-5-FU prodrugs: Physicochemical characterization of prodrugs and correlations with transdermal delivery International Journal of Pharmaceutics. 93: 27-36. DOI: 10.1016/0378-5173(93)90161-8  0.52
1992 Siegel D, Beall H, Senekowitsch C, Kasai M, Arai H, Gibson NW, Ross D. Bioreductive activation of mitomycin C by DT-diaphorase. Biochemistry. 31: 7879-85. PMID 1510975 DOI: 10.1021/Bi00149A019  0.52
1991 Sloan KB, Beall HD, Weimar WR, Villanueva R. The effect of receptor phase composition on the permeability of hairless mouse skin in diffusion cell experiments International Journal of Pharmaceutics. 73: 97-104. DOI: 10.1016/0378-5173(91)90031-I  0.52
1990 Saab AN, Sloan KB, Beall HD, Villaneuva R. Effect of aminomethyl (N-Mannich base) derivatization on the ability of S6-acetyloxymethyl-6-mercaptopurine prodrug to deliver 6-mercaptopurine through hairless mouse skin. Journal of Pharmaceutical Sciences. 79: 1099-104. PMID 2079657 DOI: 10.1002/jps.2600791212  0.52
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