Year |
Citation |
Score |
2012 |
Xu W, Lu JP, Ye QZ. Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. Journal of Medicinal Chemistry. 55: 8021-7. PMID 22913487 DOI: 10.1021/jm3008695 |
0.32 |
|
2012 |
Lu JP, Yuan XH, Ye QZ. Structural analysis of inhibition of Mycobacterium tuberculosis methionine aminopeptidase by bengamide derivatives. European Journal of Medicinal Chemistry. 47: 479-84. PMID 22118830 DOI: 10.1016/j.ejmech.2011.11.017 |
0.355 |
|
2011 |
Wang WL, Chai SC, Ye QZ. Synthesis and biological evaluation of salicylate-based compounds as a novel class of methionine aminopeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 7151-4. PMID 22001086 DOI: 10.1016/J.Bmcl.2011.09.080 |
0.429 |
|
2011 |
Chai SC, Wang WL, Ding DR, Ye QZ. Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase. European Journal of Medicinal Chemistry. 46: 3537-40. PMID 21575996 DOI: 10.1016/J.Ejmech.2011.04.056 |
0.389 |
|
2011 |
Yuan H, Chai SC, Lam CK, Howard Xu H, Ye QZ. Two methionine aminopeptidases from Acinetobacter baumannii are functional enzymes. Bioorganic & Medicinal Chemistry Letters. 21: 3395-8. PMID 21524572 DOI: 10.1016/J.Bmcl.2011.03.116 |
0.331 |
|
2011 |
Lu JP, Yuan XH, Yuan H, Wang WL, Wan B, Franzblau SG, Ye QZ. Inhibition of Mycobacterium tuberculosis methionine aminopeptidases by bengamide derivatives. Chemmedchem. 6: 1041-8. PMID 21465667 DOI: 10.1002/Cmdc.201100003 |
0.3 |
|
2010 |
Lu JP, Ye QZ. Expression and characterization of Mycobacterium tuberculosis methionine aminopeptidase type 1a. Bioorganic & Medicinal Chemistry Letters. 20: 2776-9. PMID 20363127 DOI: 10.1016/j.bmcl.2010.03.067 |
0.332 |
|
2009 |
Chai SC, Ye QZ. Metal-mediated inhibition is a viable approach for inhibiting cellular methionine aminopeptidase. Bioorganic & Medicinal Chemistry Letters. 19: 6862-4. PMID 19889537 DOI: 10.1016/J.Bmcl.2009.10.082 |
0.303 |
|
2009 |
Talukdar A, Breen M, Bacher A, Illarionov B, Fischer M, Georg G, Ye QZ, Cushman M. Discovery and development of a small molecule library with lumazine synthase inhibitory activity Journal of Organic Chemistry. 74: 5123-5134. PMID 19552377 DOI: 10.1021/Jo900238Q |
0.335 |
|
2009 |
Zhao Y, Bacher A, Illarionov B, Fischer M, Georg G, Ye QZ, Fanwick PE, Franzblau SG, Wan B, Cushman M. Discovery and development of the covalent hydrates of trifluoromethylated pyrazoles as riboflavin synthase inhibitors with antibiotic activity against Mycobacterium tuberculosis Journal of Organic Chemistry. 74: 5297-5303. PMID 19545132 DOI: 10.1021/Jo900768C |
0.346 |
|
2009 |
Wang WL, Chai SC, Ye QZ. Synthesis and structure-function analysis of Fe(II)-form-selective antibacterial inhibitors of Escherichia coli methionine aminopeptidase. Bioorganic & Medicinal Chemistry Letters. 19: 1080-3. PMID 19167218 DOI: 10.1016/J.Bmcl.2009.01.011 |
0.332 |
|
2008 |
Wang WL, Chai SC, Huang M, He HZ, Hurley TD, Ye QZ. Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity. Journal of Medicinal Chemistry. 51: 6110-20. PMID 18785729 DOI: 10.1021/Jm8005788 |
0.364 |
|
2008 |
Chai SC, Wang WL, Ye QZ. FE(II) is the native cofactor for Escherichia coli methionine aminopeptidase. The Journal of Biological Chemistry. 283: 26879-85. PMID 18669631 DOI: 10.1074/Jbc.M804345200 |
0.331 |
|
2007 |
Galam L, Hadden MK, Ma Z, Ye QZ, Yun BG, Blagg BS, Matts RL. High-throughput assay for the identification of Hsp90 inhibitors based on Hsp90-dependent refolding of firefly luciferase. Bioorganic & Medicinal Chemistry. 15: 1939-46. PMID 17223347 DOI: 10.1016/J.Bmc.2007.01.004 |
0.362 |
|
2006 |
Xie SX, Huang WJ, Ma ZQ, Huang M, Hanzlik RP, Ye QZ. Structural analysis of metalloform-selective inhibition of methionine aminopeptidase. Acta Crystallographica. Section D, Biological Crystallography. 62: 425-32. PMID 16552144 DOI: 10.1107/S0907444906003878 |
0.311 |
|
2006 |
Avila C, Hadden MK, Ma Z, Kornilayev BA, Ye QZ, Blagg BS. High-throughput screening for Hsp90 ATPase inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 3005-8. PMID 16530412 DOI: 10.1016/j.bmcl.2006.02.063 |
0.326 |
|
2006 |
Huang M, Xie SX, Ma ZQ, Hanzlik RP, Ye QZ. Metal mediated inhibition of methionine aminopeptidase by quinolinyl sulfonamides. Biochemical and Biophysical Research Communications. 339: 506-13. PMID 16300729 DOI: 10.1016/J.Bbrc.2005.11.042 |
0.367 |
|
2005 |
Huang QQ, Huang M, Nan FJ, Ye QZ. Metalloform-selective inhibition: synthesis and structure-activity analysis of Mn(II)-form-selective inhibitors of Escherichia coli methionine aminopeptidase. Bioorganic & Medicinal Chemistry Letters. 15: 5386-91. PMID 16219464 DOI: 10.1016/j.bmcl.2005.09.019 |
0.305 |
|
2005 |
Cui YM, Huang QQ, Xu J, Chen LL, Li JY, Ye QZ, Li J, Nan FJ. Identification of potent type I MetAPs inhibitors by simple bioisosteric replacement. Part 2: SAR studies of 5-heteroalkyl substituted TCAT derivatives. Bioorganic & Medicinal Chemistry Letters. 15: 4130-5. PMID 16005224 DOI: 10.1016/j.bmcl.2005.06.005 |
0.387 |
|
2005 |
Cui YM, Huang QQ, Xu J, Chen LL, Li JY, Ye QZ, Li J, Nan FJ. Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives. Bioorganic & Medicinal Chemistry Letters. 15: 3732-6. PMID 15993057 DOI: 10.1016/j.bmcl.2005.05.055 |
0.332 |
|
2004 |
Ye QZ, Xie SX, Huang M, Huang WJ, Lu JP, Ma ZQ. Metalloform-selective inhibitors of escherichia coli methionine aminopeptidase and X-ray structure of a Mn(II)-form enzyme complexed with an inhibitor. Journal of the American Chemical Society. 126: 13940-1. PMID 15506752 DOI: 10.1021/ja045864p |
0.302 |
|
2004 |
Li JY, Chen LL, Cui YM, Luo QL, Gu M, Nan FJ, Ye QZ. Characterization of full length and truncated type I human methionine aminopeptidases expressed from Escherichia coli. Biochemistry. 43: 7892-8. PMID 15196033 DOI: 10.1021/bi0360859 |
0.328 |
|
2003 |
Li JY, Chen LL, Cui YM, Luo QL, Li J, Nan FJ, Ye QZ. Specificity for inhibitors of metal-substituted methionine aminopeptidase. Biochemical and Biophysical Research Communications. 307: 172-9. PMID 12849997 |
0.312 |
|
2003 |
Luo QL, Li JY, Liu ZY, Chen LL, Li J, Qian Z, Shen Q, Li Y, Lushington GH, Ye QZ, Nan FJ. Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae. Journal of Medicinal Chemistry. 46: 2631-40. PMID 12801227 DOI: 10.1021/jm0300532 |
0.312 |
|
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