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Brett R. Blackman - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering
Website:
https://med.virginia.edu/faculty/faculty-listing/bb6w/
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Collado MS, Cole BK, Figler RA, Lawson M, Manka D, Simmers MB, Hoang S, Serrano F, Blackman BR, Sinha S, Wamhoff BR. Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes. Stem Cells Translational Medicine. PMID 28628273 DOI: 10.1002/Sctm.17-0004  0.814
2016 Feaver RE, Cole BK, Lawson MJ, Hoang SA, Marukian S, Blackman BR, Figler RA, Sanyal AJ, Wamhoff BR, Dash A. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. Jci Insight. 1: e90954. PMID 27942596 DOI: 10.1172/Jci.Insight.90954  0.765
2016 Dash A, Figler RA, Blackman BR, Marukian S, Collado MS, Lawson MJ, Hoang SA, Mackey AJ, Manka D, Cole BK, Feaver RE, Sanyal AJ, Wamhoff BR. Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 27939613 DOI: 10.1016/J.Tiv.2016.11.014  0.751
2016 Simmers MB, Cole BK, Ogletree ML, Chen Z, Xu Y, Kong LJ, Mackman N, Blackman BR, Wamhoff BR. Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells. Thrombosis Research. 143: 34-39. PMID 27179130 DOI: 10.1016/J.Thromres.2016.04.022  0.809
2015 Terelius Y, Figler RA, Marukian S, Collado MS, Lawson MJ, Mackey AJ, Manka D, Qualls CW, Blackman BR, Wamhoff BR, Dash A. Transcriptional Profiling Suggests That Nevirapine and Ritonavir Cause Drug Induced Liver Injury Through Distinct Mechanisms in Primary Human Hepatocytes. Chemico-Biological Interactions. PMID 26626330 DOI: 10.1016/J.Cbi.2015.11.023  0.354
2015 Cole BK, Simmers MB, Feaver R, Qualls CW, Collado MS, Berzin E, Figler RA, Pryor AW, Lawson M, Mackey A, Manka D, Wamhoff BR, Turk JR, Blackman BR. An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2185-95. PMID 26293464 DOI: 10.1161/Atvbaha.115.306245  0.756
2015 Feaver R, Collado S, Hoang S, Berzin E, Armstrong A, Gardner D, Liu H, Mackey A, Manka D, Shealy D, Blackman B. FRI0069 Neutralization of IL6 by Sirukumab (SIR) Inhibits Inflammation and Cellular Stress in a Human Vascular Surrogate System of Atherosclerosis Annals of the Rheumatic Diseases. 74: 444.2-445. DOI: 10.1136/annrheumdis-2015-eular.5132  0.772
2013 Dash A, Simmers MB, Deering TG, Berry DJ, Feaver RE, Hastings NE, Pruett TL, LeCluyse EL, Blackman BR, Wamhoff BR. Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro. American Journal of Physiology. Cell Physiology. 304: C1053-63. PMID 23485712 DOI: 10.1152/Ajpcell.00331.2012  0.709
2013 Feaver RE, Gelfand BD, Blackman BR. Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells. Nature Communications. 4: 1525. PMID 23443553 DOI: 10.1038/Ncomms2530  0.796
2012 Zhou G, Hamik A, Nayak L, Tian H, Shi H, Lu Y, Sharma N, Liao X, Hale A, Boerboom L, Feaver RE, Gao H, Desai A, Schmaier A, Gerson SL, ... ... Blackman BR, et al. Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice. The Journal of Clinical Investigation. 122: 4727-31. PMID 23160196 DOI: 10.1172/Jci66056  0.804
2012 Tilghman RW, Blais EM, Cowan CR, Sherman NE, Grigera PR, Jeffery ED, Fox JW, Blackman BR, Tschumperlin DJ, Papin JA, Parsons JT. Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. Plos One. 7: e37231. PMID 22623999 DOI: 10.1371/Journal.Pone.0037231  0.314
2011 Janiczek RL, Blackman BR, Roy RJ, Meyer CH, Acton ST, Epstein FH. Three-dimensional phase contrast angiography of the mouse aortic arch using spiral MRI. Magnetic Resonance in Medicine. 66: 1382-90. PMID 21656547 DOI: 10.1002/Mrm.22937  0.331
2011 Gelfand BD, Meller J, Pryor AW, Kahn M, Bortz PD, Wamhoff BR, Blackman BR. Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1625-33. PMID 21527747 DOI: 10.1161/Atvbaha.111.227827  0.712
2010 Tilghman RW, Cowan CR, Mih JD, Koryakina Y, Gioeli D, Slack-Davis JK, Blackman BR, Tschumperlin DJ, Parsons JT. Matrix rigidity regulates cancer cell growth and cellular phenotype Plos One. 5. PMID 20886123 DOI: 10.1371/Journal.Pone.0012905  0.345
2010 Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circulation Research. 106: 1703-11. PMID 20378855 DOI: 10.1161/Circresaha.109.216283  0.811
2010 Orr AW, Hastings NE, Blackman BR, Wamhoff BR. Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. Journal of Vascular Research. 47: 168-80. PMID 19851078 DOI: 10.1159/000250095  0.81
2009 Hastings NE, Feaver RE, Lee MY, Wamhoff BR, Blackman BR. Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 725-31. PMID 19229069 DOI: 10.1161/Atvbaha.109.184382  0.764
2009 Jin L, Hastings NE, Blackman BR, Somlyo AV. Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury. Journal of Muscle Research and Cell Motility. 30: 41-55. PMID 19205907 DOI: 10.1007/S10974-009-9173-1  0.809
2009 Thomas JA, Deaton RA, Hastings NE, Shang Y, Moehle CW, Eriksson U, Topouzis S, Wamhoff BR, Blackman BR, Owens GK. PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns. American Journal of Physiology. Heart and Circulatory Physiology. 296: H442-52. PMID 19028801 DOI: 10.1152/Ajpheart.00165.2008  0.812
2008 Anderson CR, Hastings NE, Blackman BR, Price RJ. Capillary sprout endothelial cells exhibit a CD36 low phenotype: regulation by shear stress and vascular endothelial growth factor-induced mechanism for attenuating anti-proliferative thrombospondin-1 signaling. The American Journal of Pathology. 173: 1220-8. PMID 18772338 DOI: 10.2353/Ajpath.2008.071194  0.799
2008 Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707  0.801
2008 Orr AW, Hahn C, Blackman BR, Schwartz MA. p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow. Circulation Research. 103: 671-9. PMID 18669917 DOI: 10.1161/Circresaha.108.182097  0.398
2008 Feaver RE, Hastings NE, Pryor A, Blackman BR. GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1534-41. PMID 18556570 DOI: 10.1161/Atvbaha.108.167999  0.786
2007 Hastings NE, Simmers MB, McDonald OG, Wamhoff BR, Blackman BR. Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. American Journal of Physiology. Cell Physiology. 293: C1824-33. PMID 17913848 DOI: 10.1152/Ajpcell.00385.2007  0.798
2007 Simmers MB, Pryor AW, Blackman BR. Arterial shear stress regulates endothelial cell-directed migration, polarity, and morphology in confluent monolayers. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1937-46. PMID 17586613 DOI: 10.1152/Ajpheart.00534.2007  0.806
2007 Orr AW, Stockton R, Simmers MB, Sanders JM, Sarembock IJ, Blackman BR, Schwartz MA. Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. The Journal of Cell Biology. 176: 719-27. PMID 17312022 DOI: 10.1083/Jcb.200609008  0.814
2007 Orr AW, Stockton R, Simmers M, Sanders JM, Blackman BR, Schwartz MA. Matrix‐specific PAK activation regulates vascular permeability in atherosclerosis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A268-D  0.807
2007 Orr AW, Stockton R, Simmers MB, Sanders JM, Sarembock IJ, Blackman BR, Alexander Schwartz M. Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis The Journal of Experimental Medicine. 204: i7-i7. DOI: 10.1084/JEM2043OIA7  0.774
2006 Gelfand BD, Epstein FH, Blackman BR. Spatial and spectral heterogeneity of time-varying shear stress profiles in the carotid bifurcation by phase-contrast MRI. Journal of Magnetic Resonance Imaging : Jmri. 24: 1386-92. PMID 17083089 DOI: 10.1002/Jmri.20765  0.682
2006 Wieghaus KA, Capitosti SM, Anderson CR, Price RJ, Blackman BR, Brown ML, Botchwey EA. Small molecule inducers of angiogenesis for tissue engineering. Tissue Engineering. 12: 1903-13. PMID 16889520 DOI: 10.1089/Ten.2006.12.1903  0.427
2006 GARCÍA-CARDEÑA G, COMANDER JI, BLACKMAN BR, ANDERSON KR, GIMBRONE MA. Mechanosensitive Endothelial Gene Expression Profiles Annals of the New York Academy of Sciences. 947: 1-6. DOI: 10.1111/J.1749-6632.2001.Tb03924.X  0.398
2004 Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, Kamm RD, García-Cardeña G, Gimbrone MA. Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proceedings of the National Academy of Sciences of the United States of America. 101: 14871-6. PMID 15466704 DOI: 10.1073/Pnas.0406073101  0.372
2004 Browning E, Pryor A, Blackman B. Dynamic Remodeling Of Endothelial Adheren Junctions In Response To Long-Term Adaptation To Arterial Hemodynamics Cardiovascular Pathology. 13: 4-5. DOI: 10.1016/J.Carpath.2004.03.007  0.32
2002 Blackman BR, García-Cardeña G, Gimbrone MA. A new in vitro model to evaluate differential responses of endothelial cells to simulated arterial shear stress waveforms. Journal of Biomechanical Engineering. 124: 397-407. PMID 12188206 DOI: 10.1115/1.1486468  0.357
2001 García-Cardeña G, Comander J, Anderson KR, Blackman BR, Gimbrone MA. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype Proceedings of the National Academy of Sciences of the United States of America. 98: 4478-4485. PMID 11296290 DOI: 10.1073/Pnas.071052598  0.426
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