| Year |
Citation |
Score |
| 2024 |
Sun F, Xiao G, Qu Z. PDLIM2 is a novel E5 ubiquitin ligase enhancer that stabilizes ROC1 and recruits the ROC1-SCF ubiquitin ligase to ubiquitinate and degrade NF-κB RelA. Cell & Bioscience. 14: 99. PMID 39080804 DOI: 10.1186/s13578-024-01281-x |
0.408 |
|
| 2024 |
Sun F, Xiao Y, Shapiro SD, Qu Z, Xiao G. Critical and distinct roles of cell type-specific NF-κB2 in lung cancer. Jci Insight. 9. PMID 38385745 DOI: 10.1172/jci.insight.164188 |
0.356 |
|
| 2018 |
Li L, Han L, Sun F, Zhou J, Ohaegbulam KC, Tang X, Zang X, Steinbrecher KA, Qu Z, Xiao G. NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8 T cells for tumor promotion. Oncoimmunology. 7: e1435250. PMID 29872577 DOI: 10.1080/2162402X.2018.1435250 |
0.45 |
|
| 2017 |
Zhou J, Qu Z, Sun F, Han L, Li L, Yan S, Stabile LP, Chen LF, Siegfried JM, Xiao G. Myeloid STAT3 promotes lung tumorigenesis by transforming tumor immunosurveillance into tumor-promoting inflammation. Cancer Immunology Research. PMID 28108629 DOI: 10.1158/2326-6066.Cir-16-0073 |
0.335 |
|
| 2015 |
Sun F, Qu Z, Xiao Y, Zhou J, Burns TF, Stabile LP, Siegfried JM, Xiao G. NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function. Oncogene. PMID 26300007 DOI: 10.1038/Onc.2015.299 |
0.521 |
|
| 2015 |
Qu Z, Xiao G. Systematic detection of noncanonical NF-κB activation. Methods in Molecular Biology (Clifton, N.J.). 1280: 121-54. PMID 25736747 DOI: 10.1007/978-1-4939-2422-6_8 |
0.515 |
|
| 2015 |
Qu Z, Xiao G. Identification and characterization of novel NF-kB dependent genes involved in HTLV-I pathogenesis Retrovirology. 12. DOI: 10.1186/1742-4690-12-S1-P93 |
0.45 |
|
| 2013 |
Wu X, Qi J, Bradner JE, Xiao G, Chen LF. Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling. The Journal of Biological Chemistry. 288: 36094-105. PMID 24189064 DOI: 10.1074/Jbc.M113.485029 |
0.533 |
|
| 2013 |
Kimura R, Senba M, Cutler SJ, Ralph SJ, Xiao G, Mori N. Human T cell leukemia virus type I tax-induced IκB-ζ modulates tax-dependent and tax-independent gene expression in T cells. Neoplasia (New York, N.Y.). 15: 1110-24. PMID 24027435 DOI: 10.1593/Neo.131140 |
0.496 |
|
| 2012 |
Xiao G. NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination? Retrovirology. 9: 78. PMID 23009565 DOI: 10.1186/1742-4690-9-78 |
0.491 |
|
| 2012 |
Arabi A, Ullah K, Branca RM, Johansson J, Bandarra D, Haneklaus M, Fu J, Ariës I, Nilsson P, Den Boer ML, Pokrovskaja K, Grandér D, Xiao G, Rocha S, Lehtiö J, et al. Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway. Nature Communications. 3: 976. PMID 22864569 DOI: 10.1038/ncomms1975 |
0.488 |
|
| 2012 |
Qu Z, Fu J, Ma H, Zhou J, Jin M, Mapara MY, Grusby MJ, Xiao G. PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease. Cell & Bioscience. 2: 23. PMID 22731402 DOI: 10.1186/2045-3701-2-23 |
0.358 |
|
| 2011 |
Xiao G, Fu J. NF-κB and cancer: a paradigm of Yin-Yang. American Journal of Cancer Research. 1: 192-221. PMID 21969033 |
0.395 |
|
| 2011 |
Qu Z, Xiao G. Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis. Viruses. 3: 714-49. PMID 21743832 DOI: 10.3390/v3060714 |
0.346 |
|
| 2011 |
Imanishi Y, Hu B, Xiao G, Yao X, Cheng SY. Angiopoietin-2, an angiogenic regulator, promotes initial growth and survival of breast cancer metastases to the lung through the integrin-linked kinase (ILK)-AKT-B cell lymphoma 2 (Bcl-2) pathway. The Journal of Biological Chemistry. 286: 29249-60. PMID 21680733 DOI: 10.1074/Jbc.M111.235689 |
0.332 |
|
| 2011 |
Fu J, Qu Z, Yan P, Ishikawa C, Aqeilan RI, Rabson AB, Xiao G. The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis. Blood. 117: 1652-61. PMID 21115974 DOI: 10.1182/Blood-2010-08-303073 |
0.53 |
|
| 2011 |
Fu J, Qu Z, Yan P, Li S, Song X, Ishikawa C, Aqeilan RI, Mori N, Rabson AB, Xiao G. Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis Retrovirology. 8: A157. DOI: 10.1186/1742-4690-8-S1-A157 |
0.542 |
|
| 2010 |
Fu J, Yan P, Li S, Qu Z, Xiao G. Molecular determinants of PDLIM2 in suppressing HTLV-I Tax-mediated tumorigenesis. Oncogene. 29: 6499-6507. PMID 20838382 DOI: 10.1038/Onc.2010.374 |
0.395 |
|
| 2010 |
Qu Z, Fu J, Yan P, Hu J, Cheng SY, Xiao G. Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer. The Journal of Biological Chemistry. 285: 11786-92. PMID 20185823 DOI: 10.1074/Jbc.M109.086561 |
0.4 |
|
| 2010 |
Qu Z, Yan P, Fu J, Jiang J, Grusby MJ, Smithgall TE, Xiao G. DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target. Cancer Research. 70: 1766-72. PMID 20145149 DOI: 10.1158/0008-5472.Can-09-3263 |
0.503 |
|
| 2010 |
Huang B, Qu Z, Victor A, Zhang C, Yang X, Ito K, Xiao G, Ito Y, Shapiro D, Chen L. Abstract LB-5: RUNX3 targets estrogen receptorαfor proteasome-mediated degradation suppressing breast cancer tumorigenesis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-5 |
0.316 |
|
| 2009 |
Yan P, Qu Z, Ishikawa C, Mori N, Xiao G. Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax. Neoplasia (New York, N.Y.). 11: 1036-41. PMID 19794962 DOI: 10.1593/Neo.09752 |
0.379 |
|
| 2009 |
Yan P, Fu J, Qu Z, Li S, Tanaka T, Grusby MJ, Xiao G. PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation. Blood. 113: 4370-80. PMID 19131544 DOI: 10.1182/Blood-2008-10-185660 |
0.406 |
|
| 2008 |
Vatsyayan J, Qing G, Xiao G, Hu J. SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processing. Embo Reports. 9: 885-90. PMID 18617892 DOI: 10.1038/embor.2008.122 |
0.737 |
|
| 2007 |
Yan P, Qing G, Qu Z, Wu CC, Rabson A, Xiao G. Targeting autophagic regulation of NFkappaB in HTLV-I transformed cells by geldanamycin: implications for therapeutic interventions. Autophagy. 3: 600-3. PMID 17671417 DOI: 10.4161/Auto.4761 |
0.671 |
|
| 2007 |
Qing G, Yan P, Qu Z, Liu H, Xiao G. Hsp90 regulates processing of NF-kappa B2 p100 involving protection of NF-kappa B-inducing kinase (NIK) from autophagy-mediated degradation. Cell Research. 17: 520-30. PMID 17563756 DOI: 10.1038/Cr.2007.47 |
0.745 |
|
| 2007 |
Xiao G. Autophagy and NF-kappaB: fight for fate. Cytokine & Growth Factor Reviews. 18: 233-43. PMID 17485237 DOI: 10.1016/j.cytogfr.2007.04.006 |
0.396 |
|
| 2007 |
Qing G, Qu Z, Xiao G. Endoproteolytic processing of C-terminally truncated NF-kappaB2 precursors at kappaB-containing promoters. Proceedings of the National Academy of Sciences of the United States of America. 104: 5324-9. PMID 17363471 DOI: 10.1073/Pnas.0609914104 |
0.711 |
|
| 2006 |
Qing G, Yan P, Xiao G. Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK). Cell Research. 16: 895-901. PMID 17088896 DOI: 10.1038/Sj.Cr.7310109 |
0.673 |
|
| 2006 |
Xiao G, Rabson AB, Young W, Qing G, Qu Z. Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease. Cytokine & Growth Factor Reviews. 17: 281-93. PMID 16793322 DOI: 10.1016/J.Cytogfr.2006.04.005 |
0.722 |
|
| 2005 |
Qing G, Qu Z, Xiao G. Stabilization of basally translated NF-kappaB-inducing kinase (NIK) protein functions as a molecular switch of processing of NF-kappaB2 p100. The Journal of Biological Chemistry. 280: 40578-82. PMID 16223731 DOI: 10.1074/Jbc.M508776200 |
0.742 |
|
| 2005 |
Qing G, Xiao G. Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100. The Journal of Biological Chemistry. 280: 9765-8. PMID 15677466 DOI: 10.1074/Jbc.C400502200 |
0.718 |
|
| 2005 |
Qing G, Qu Z, Xiao G. Regulation of NF-kappa B2 p100 processing by its cis-acting domain. The Journal of Biological Chemistry. 280: 18-27. PMID 15485830 DOI: 10.1074/Jbc.M406619200 |
0.713 |
|
| 2004 |
Qu Z, Qing G, Rabson A, Xiao G. Tax deregulation of NF-kappaB2 p100 processing involves both beta-TrCP-dependent and -independent mechanisms. The Journal of Biological Chemistry. 279: 44563-72. PMID 15310758 DOI: 10.1074/Jbc.M403689200 |
0.724 |
|
| 2004 |
Xiao G, Fong A, Sun SC. Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation. The Journal of Biological Chemistry. 279: 30099-105. PMID 15140882 DOI: 10.1074/Jbc.M401428200 |
0.523 |
|
| 2003 |
Sun SC, Xiao G. Deregulation of NF-kappaB and its upstream kinases in cancer. Cancer Metastasis Reviews. 22: 405-22. PMID 12884915 DOI: 10.1023/A:1023733231406 |
0.428 |
|
| 2001 |
Xiao G, Cvijic ME, Fong A, Harhaj EW, Uhlik MT, Waterfield M, Sun SC. Retroviral oncoprotein tax induces processing of NF-κB2/p100 in T cells: Evidence for the involvement of IKKα Embo Journal. 20: 6805-6815. PMID 11726516 DOI: 10.1093/Emboj/20.23.6805 |
0.544 |
|
| 2001 |
Senftleben U, Cao Y, Xiao G, Greten FR, Krähn G, Bonizzi G, Chen Y, Hu Y, Fong A, Sun SC, Karin M. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science (New York, N.Y.). 293: 1495-9. PMID 11520989 DOI: 10.1126/Science.1062677 |
0.481 |
|
| 2001 |
Xiao G, Harhaj EW, Sun SC. NF-κB-inducing kinase regulates the processing of NF-κB2 p100 Molecular Cell. 7: 401-409. PMID 11239468 DOI: 10.1016/S1097-2765(01)00187-3 |
0.541 |
|
| 2000 |
Sun SC, Harhaj EW, Xiao G, Good L. Activation of I-κB kinase by the HTLV type 1 Tax protein: Mechanistic insights into the adaptor function of IKKγ Aids Research and Human Retroviruses. 16: 1591-1596. PMID 11080796 DOI: 10.1089/08892220050193001 |
0.411 |
|
| 2000 |
Xiao G, Sun SC. Activation of IKKα and IKKβ through their fusion with HTLV-I tax protein Oncogene. 19: 5198-5203. PMID 11064457 DOI: 10.1038/sj.onc.1203894 |
0.33 |
|
| 2000 |
Xiao G, Harhaj EW, Sun SC. Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in tax-mediated activation of IKK Journal of Biological Chemistry. 275: 34060-34067. PMID 10906125 |
0.309 |
|
| 2000 |
Xiao G, Sun SC. Negative regulation of the nuclear factor κB-inducing kinase by a cis- acting domain Journal of Biological Chemistry. 275: 21081-21085. PMID 10887201 DOI: 10.1074/jbc.M002552200 |
0.418 |
|
| 2000 |
Rivera-Walsh I, Cvijic ME, Xiao G, Sun SC. The NF-κB signaling pathway is not required for fas ligand gene induction but mediates protection from activation-induced cell death Journal of Biological Chemistry. 275: 25222-25230. PMID 10837465 DOI: 10.1074/Jbc.M000444200 |
0.388 |
|
| 2000 |
Harhaj EW, Good L, Xiao G, Uhlik M, Cvijic ME, Rivera-Walsh I, Sun SC. Somatic mutagenesis studies of NF-κB signaling in human T cells: Evidence for an essential role of IKKγ, in NP-κB activation by T-cell costimulatory signals and HTLV-I Tax protein Oncogene. 19: 1448-1456. PMID 10723136 DOI: 10.1038/sj.onc.1203445 |
0.345 |
|
| 1998 |
Uhlik M, Good L, Xiao G, Harhaj EW, Zandi E, Karin M, Sun SC. NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I tax-mediated NF-κB activation Journal of Biological Chemistry. 273: 21132-21136. PMID 9694868 DOI: 10.1074/Jbc.273.33.21132 |
0.451 |
|
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