Jes K. Klarlund - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Cell Biology, Molecular Biology, Physiology Biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Klarlund JK, Callaghan JD, Stella NA, Kowalski RP, McNamara NA, Shanks RMQ. Use of Collagen Binding Domains to Deliver Molecules to the Cornea. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 31593501 DOI: 10.1089/Jop.2019.0065  0.346
2015 Brothers KM, Stella NA, Hunt KM, Romanowski EG, Liu X, Klarlund JK, Shanks RM. Putting on the brakes: Bacterial impediment of wound healing. Scientific Reports. 5: 14003. PMID 26365869 DOI: 10.1038/Srep14003  0.361
2012 Klarlund JK. Dual modes of motility at the leading edge of migrating epithelial cell sheets. Proceedings of the National Academy of Sciences of the United States of America. 109: 15799-804. PMID 23019364 DOI: 10.1073/Pnas.1210992109  0.483
2011 Block ER, Tolino MA, Klarlund JK. Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor. Cellular Signalling. 23: 2051-5. PMID 21840393 DOI: 10.1016/J.Cellsig.2011.07.021  0.791
2011 Tolino MA, Block ER, Klarlund JK. Brief treatment with heparin-binding EGF-like growth factor, but not with EGF, is sufficient to accelerate epithelial wound healing. Biochimica Et Biophysica Acta. 1810: 875-8. PMID 21640162 DOI: 10.1016/J.Bbagen.2011.05.011  0.77
2011 Klarlund JK, Block ER. Free edges in epithelia as cues for motility. Cell Adhesion & Migration. 5: 106-10. PMID 20953155 DOI: 10.4161/Cam.5.2.13728  0.777
2010 Block ER, Tolino MA, Lozano JS, Lathrop KL, Sullenberger RS, Mazie AR, Klarlund JK. Free edges in epithelial cell sheets stimulate epidermal growth factor receptor signaling. Molecular Biology of the Cell. 21: 2172-81. PMID 20462956 DOI: 10.1091/Mbc.E09-12-1026  0.795
2010 Block ER, Tolino MA, Klarlund JK. Pyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells. The Journal of Biological Chemistry. 285: 13372-9. PMID 20215112 DOI: 10.1074/Jbc.M109.083089  0.801
2009 Klarlund JK, Cherniack AD, McMahon M, Czech MP. P-63: Activation of the Raf/Mitogen-activated protein kinase pathway is not sufficient for disassembly of Grb2/Sos or p21ras desensitization Experimental and Clinical Endocrinology & Diabetes. 104: 128-129. DOI: 10.1055/S-0029-1211606  0.706
2008 Block ER, Klarlund JK. Wounding sheets of epithelial cells activates the epidermal growth factor receptor through distinct short- and long-range mechanisms. Molecular Biology of the Cell. 19: 4909-17. PMID 18799627 DOI: 10.1091/Mbc.E08-01-0097  0.801
2008 Lozano JS, Chay EY, Healey J, Sullenberger R, Klarlund JK. Activation of the epidermal growth factor receptor by hydrogels in artificial tears. Experimental Eye Research. 86: 500-5. PMID 18242602 DOI: 10.1016/J.Exer.2007.12.003  0.471
2007 Spix JK, Chay EY, Block ER, Klarlund JK. Hepatocyte growth factor induces epithelial cell motility through transactivation of the epidermal growth factor receptor. Experimental Cell Research. 313: 3319-25. PMID 17643426 DOI: 10.1016/J.Yexcr.2007.06.006  0.795
2006 Mazie AR, Spix JK, Block ER, Achebe HB, Klarlund JK. Epithelial cell motility is triggered by activation of the EGF receptor through phosphatidic acid signaling. Journal of Cell Science. 119: 1645-54. PMID 16569667 DOI: 10.1242/Jcs.02858  0.783
2004 Block ER, Matela AR, SundarRaj N, Iszkula ER, Klarlund JK. Wounding induces motility in sheets of corneal epithelial cells through loss of spatial constraints: role of heparin-binding epidermal growth factor-like growth factor signaling. The Journal of Biological Chemistry. 279: 24307-12. PMID 15039441 DOI: 10.1074/Jbc.M401058200  0.799
2001 Klarlund JK, Holik J, Chawla A, Park JG, Buxton J, Czech MP. Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1. The Journal of Biological Chemistry. 276: 40065-70. PMID 11445584 DOI: 10.1074/Jbc.M105260200  0.634
2001 Klarlund JK, Czech MP. Isolation and properties of GRP1, an ADP-ribosylation factor (ARF)-guanine nucleotide exchange protein regulated by phosphatidylinositol 3,4,5-trisphosphate. Methods in Enzymology. 329: 279-89. PMID 11210545 DOI: 10.1016/S0076-6879(01)29089-2  0.614
2000 Lietzke SE, Bose S, Cronin T, Klarlund J, Chawla A, Czech MP, Lambright DG. Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains. Molecular Cell. 6: 385-94. PMID 10983985 DOI: 10.1016/S1097-2765(00)00038-1  0.575
2000 Klarlund JK, Tsiaras W, Holik JJ, Chawla A, Czech MP. Distinct polyphosphoinositide binding selectivities for pleckstrin homology domains of GRP1-like proteins based on diglycine versus triglycine motifs. The Journal of Biological Chemistry. 275: 32816-21. PMID 10913124 DOI: 10.1074/Jbc.M002435200  0.587
2000 Emoto M, Klarlund JK, Waters SB, Hu V, Buxton JM, Chawla A, Czech MP. A role for phospholipase D in GLUT4 glucose transporter translocation. The Journal of Biological Chemistry. 275: 7144-51. PMID 10702282 DOI: 10.1074/Jbc.275.10.7144  0.575
1999 Langille SE, Patki V, Klarlund JK, Buxton JM, Holik JJ, Chawla A, Corvera S, Czech MP. ADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1. The Journal of Biological Chemistry. 274: 27099-104. PMID 10480924 DOI: 10.1074/Jbc.274.38.27099  0.778
1998 Clodi M, Vollenweider P, Klarlund J, Nakashima N, Martin S, Czech MP, Olefsky JM. Effects of General Receptor for Phosphoinositides 1 on Insulin and Insulin-Like Growth Factor I-Induced Cytoskeletal Rearrangement, Glucose Transporter-4 Translocation, and Deoxyribonucleic Acid Synthesis* * This work was supported by Grants J 01287-Med and J 1584-Med from the Erwin Schrödinger Stipendium by the Fonds zur Förderung der wissenschaftlichen Forschung, Austria (to M.C.); a grant from the Schweizerische Stiftung für Medizinisch-Biologische Stipendien (to P.V.); and in part by NIH Grant DK-33651. Endocrinology. 139: 4984-4990. PMID 28204246 DOI: 10.1210/Endo.139.12.6351  0.611
1998 Klarlund JK, Rameh LE, Cantley LC, Buxton JM, Holik JJ, Sakelis C, Patki V, Corvera S, Czech MP. Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. The Journal of Biological Chemistry. 273: 1859-62. PMID 9442017 DOI: 10.1074/Jbc.273.4.1859  0.728
1997 Klarlund JK, Guilherme A, Holik JJ, Virbasius JV, Chawla A, Czech MP. Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains. Science (New York, N.Y.). 275: 1927-30. PMID 9072969 DOI: 10.1126/Science.275.5308.1927  0.784
1997 Guilherme A, Klarlund JK, Krystal G, Czech MP. Regulation of phosphatidylinositol 3,4,5-trisphosphate 5'-phosphatase activity by insulin. The Journal of Biological Chemistry. 271: 29533-6. PMID 8939879 DOI: 10.1074/Jbc.271.47.29533  0.612
1996 Rigby MR, Bortell R, Greiner DL, Czech MP, Klarlund JK, Mordes JP, Rossini AA. The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal. Diabetes. 45: 1419-26. PMID 8826980 DOI: 10.2337/Diab.45.10.1419  0.589
1996 Klarlund JK, Cherniack AD, McMahon M, Czech MP. Role of the Raf/mitogen-activated protein kinase pathway in p21(ras) desensitization Journal of Biological Chemistry. 271: 16674-16677. PMID 8663295 DOI: 10.1074/Jbc.271.28.16674  0.74
1995 Cherniack AD, Klarlund JK, Conway BR, Czech MP. Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin. The Journal of Biological Chemistry. 270: 1485-8. PMID 7829473 DOI: 10.1074/Jbc.270.4.1485  0.697
1995 Klarlund JK, Cherniack AD, Czech MP. Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors Journal of Biological Chemistry. 270: 23421-23428. PMID 7559502 DOI: 10.1074/Jbc.270.40.23421  0.734
1993 Baltensperger K, Kozma LM, Cherniack AD, Klarlund JK, Chawla A, Banerjee U, Czech MP. Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes. Science (New York, N.Y.). 260: 1950-2. PMID 8391166 DOI: 10.1126/Science.8391166  0.738
1993 Kozma L, Baltensperger K, Klarlund J, Porras A, Santos E, Czech MP. The ras signaling pathway mimics insulin action on glucose transporter translocation. Proceedings of the National Academy of Sciences of the United States of America. 90: 4460-4. PMID 8389451 DOI: 10.1073/Pnas.90.10.4460  0.576
1988 Klarlund JK, Latini S, Forchhammer J. Numerous proteins phosphorylated on tyrosine and enhanced tyrosine kinase activities in vanadate-treated NIH 3T3 fibroblasts Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 971: 112-120. DOI: 10.1016/0167-4889(88)90167-X  0.444
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