Ari M.P. Koskinen, Ph.D. - Publications

Affiliations: 
Chemistry Aalto University, Espoo, Finland 
Area:
organic synthesis, natural products, chemical biology
Website:
http://users.aalto.fi/akoskine/

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Huy PH, Westphal JC, Koskinen AM. Concise, stereodivergent and highly stereoselective synthesis of cis- and trans-2-substituted 3-hydroxypiperidines - development of a phosphite-driven cyclodehydration. Beilstein Journal of Organic Chemistry. 10: 369-83. PMID 24605158 DOI: 10.3762/Bjoc.10.35  0.355
2014 Laine AE, Lood C, Koskinen AM. Pharmacological importance of optically active tetrahydro-β-carbolines and synthetic approaches to create the C1 stereocenter. Molecules (Basel, Switzerland). 19: 1544-67. PMID 24473212 DOI: 10.3390/Molecules19021544  0.312
2014 Koskinen AM. Boron enolate chemistry toward the syntheses of polyketide stereotetrads. Chemical Record (New York, N.Y.). 14: 52-61. PMID 24420331 DOI: 10.1002/Tcr.201300033  0.405
2013 Passiniemi M, Koskinen AM. Garner's aldehyde as a versatile intermediate in the synthesis of enantiopure natural products. Beilstein Journal of Organic Chemistry. 9: 2641-59. PMID 24367429 DOI: 10.3762/Bjoc.9.300  0.352
2013 Huy PH, Koskinen AM. Efficient, stereodivergent access to 3-piperidinols by traceless P(OEt)3 cyclodehydration. Organic Letters. 15: 5178-81. PMID 24090120 DOI: 10.1021/Ol4026588  0.333
2013 Karjalainen OK, Nieger M, Koskinen AM. Diastereoselective intramolecular allyl transfer from allyl carbamate accompanied by 5-endo-trig ring closure. Angewandte Chemie (International Ed. in English). 52: 2551-4. PMID 23341176 DOI: 10.1002/Anie.201209443  0.368
2011 Passiniemi M, Koskinen AM. Asymmetric synthesis of Pachastrissamine (Jaspine B) and its diastereomers via η3-allylpalladium intermediates. Organic & Biomolecular Chemistry. 9: 1774-83. PMID 21264408 DOI: 10.1039/C0Ob00643B  0.356
2010 Karppanen EJ, Koskinen AM. The 9-phenyl-9-fluorenyl group for nitrogen protection in enantiospecific synthesis. Molecules (Basel, Switzerland). 15: 6512-47. PMID 20877241 DOI: 10.3390/Molecules15096512  0.357
2010 Habrant D, Koskinen AM. Towards the total synthesis of calyculin C: preparation of the C(9)-C(25) spiroketal-dipropionate unit. Organic & Biomolecular Chemistry. 8: 4364-73. PMID 20683542 DOI: 10.1039/C0Ob00092B  0.389
2010 Habrant D, Rauhala V, Koskinen AM. Conversion of carbonyl compounds to alkynes: general overview and recent developments. Chemical Society Reviews. 39: 2007-17. PMID 20502799 DOI: 10.1039/B915418C  0.323
2010 Karjalainen OK, Passiniemi M, Koskinen AM. Short and straightforward synthesis of (-)-1-deoxygalactonojirimycin. Organic Letters. 12: 1145-7. PMID 20170191 DOI: 10.1021/Ol100037C  0.345
2010 Fagerholm AE, Habrant D, Koskinen AM. Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C. Marine Drugs. 8: 122-72. PMID 20161975 DOI: 10.3390/Md80100122  0.328
2010 Käsnänen H, Myllymäki MJ, Minkkilä A, Kataja AO, Saario SM, Nevalainen T, Koskinen AM, Poso A. 3-Heterocycle-phenyl N-alkylcarbamates as FAAH inhibitors: design, synthesis and 3D-QSAR studies. Chemmedchem. 5: 213-31. PMID 20024981 DOI: 10.1002/Cmdc.200900390  0.303
2009 Myllymäki MJ, Käsnänen H, Kataja AO, Lahtela-Kakkonen M, Saario SM, Poso A, Koskinen AM. Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields. European Journal of Medicinal Chemistry. 44: 4179-91. PMID 19539407 DOI: 10.1016/J.Ejmech.2009.05.012  0.331
2007 Kumpulainen ET, Koskinen AM, Rissanen K. Total synthesis of amaminol A: establishment of the absolute stereochemistry. Organic Letters. 9: 5043-5. PMID 17956115 DOI: 10.1021/Ol7022856  0.362
2007 Abe AM, Sauerland SJ, Koskinen AM. Highly enantioselective conjugate addition of thiols using mild scandium triflate catalysis. The Journal of Organic Chemistry. 72: 5411-3. PMID 17550292 DOI: 10.1021/Jo070492Z  0.328
2005 Koskinen AM, Helaja J, Kumpulainen ET, Koivisto J, Mansikkamäki H, Rissanen K. Locked conformations for proline pyrrolidine ring: synthesis and conformational analysis of cis- and trans-4-tert-butylprolines. The Journal of Organic Chemistry. 70: 6447-53. PMID 16050708 DOI: 10.1021/Jo050838A  0.375
2005 Tois J, Vahermo M, Koskinen A. Novel and convenient synthesis of 4(1H)quinolones Tetrahedron Letters. 46: 735-737. DOI: 10.1016/J.Tetlet.2004.12.046  0.301
2003 Karisalmi K, Rissanen K, Koskinen AM. An enantioselective synthesis of the C(33)-C(37) fragment of Amphotericin B. Organic & Biomolecular Chemistry. 1: 3193-6. PMID 14527151 DOI: 10.1039/B305845J  0.356
2002 Nevalainen M, Koskinen AM. Total synthesis of nor-1,6-germacradien-5-ols. The Journal of Organic Chemistry. 67: 1554-60. PMID 11871886 DOI: 10.1021/Jo016110L  0.335
2002 Koskinen A, Pihko P. Laboratoriotyöt integroidaan luentoihin: Teknillisen korkeakoulun orgaanisen kemian laboratorio pyrkii Euroopan kärkiviisikkoon Kemia-Kemi/Finnish Chemical Journal. 29: 31-33.  0.53
2001 Nevalainen M, Kauppinen PM, Koskinen AM. Synthesis of Fmoc-protected trans-4-methylproline. The Journal of Organic Chemistry. 66: 2061-6. PMID 11300901 DOI: 10.1021/Jo005726S  0.326
2000 Koskinen PM, Koskinen AM. Total synthesis of sphingosine and its analogs. Methods in Enzymology. 311: 458-79. PMID 10563344 DOI: 10.1016/S0076-6879(00)11100-0  0.374
2000 Lajunen M, Koskinen A. Hajos–Parrish ketone: approaches toward C-ring precursors of 7-deoxytaxol Journal of the Chemical Society-Perkin Transactions 1. 1439-1443. DOI: 10.1039/A909471G  0.4
1999 Lindvall MK, Koskinen AM. Origins of Stereoselectivity in the Corey-Chaykovsky Reaction. Insights from Quantum Chemistry. The Journal of Organic Chemistry. 64: 4596-4606. PMID 11674528 DOI: 10.1021/Jo9818935  0.32
1998 Pihko PM, Koskinen AM. Synthesis of the C(26)-C(32) Oxazole Fragment of Calyculin C: A Test Case for Oxazole Syntheses. The Journal of Organic Chemistry. 63: 92-98. PMID 11674047 DOI: 10.1021/Jo971167M  0.612
1997 Lindvall MK, Pihko PM, Koskinen AM. The binding mode of calyculin A to protein phosphatase-1. A novel spiroketal vector model. The Journal of Biological Chemistry. 272: 23312-6. PMID 9287341 DOI: 10.1074/Jbc.272.37.23312  0.559
1993 Koskinen A. Asymmetric synthesis of chiral macrocyclic ligands Pure and Applied Chemistry. 65: 1465-1470. DOI: 10.1351/Pac199365071465  0.308
1987 Lounasmaa M, Karvinen E, Koskinen A, Jokela R. Novel applications of the modified polonovski reaction-IX. A new route to wenkert's enamine Tetrahedron. 43: 2135-2146. DOI: 10.1016/S0040-4020(01)86795-8  0.567
1986 Lounasmaa M, Koskinen A, O'Connell J. NMR Studies of Alkaloids. Assignment of the Configuration at C(20) in Tubotaiwine (Dihydrocondylocarpine) Helvetica Chimica Acta. 69: 1343-1348. DOI: 10.1002/Hlca.19860690608  0.536
1986 Lounasmaa M, Koskinen A, O'connell J. NMR Studies of Alkaloids. Assignment of the Configuration at C(20) in Tubotaiwine (Dihydrocondylocarpine). Cheminform. 17. DOI: 10.1002/Chin.198652301  0.534
1985 Koskinen AM, Rapoport H. Synthetic and conformational studies on anatoxin-a: a potent acetylcholine agonist. Journal of Medicinal Chemistry. 28: 1301-9. PMID 4032432 DOI: 10.1002/Chin.198552240  0.462
1984 Lounasmaa M, Koskinen A. Modified Polonovski reaction, a versatile synthetic tool Heterocycles. 22: 1591-1612. DOI: 10.1002/Chin.198448368  0.512
1984 Koskinen A, Lounasmaa M. Tryptophan derived pyridinium salts: preparation, reductive cyanation and addition reactions Heterocycles. 22: 733-744. DOI: 10.1002/Chin.198439169  0.533
1983 Lounasmaa M, Koskinen A. 13C NMR Spectral Analysis of a-Aminonitriles Heterocycles. 20: 563. DOI: 10.3987/R-1983-04-0563  0.517
1983 Lounasmaa M, Koskinen A, somersalo P. NMR Spectroacopic Studies of Tryptophan Derivatives Heterocycles. 20: 557. DOI: 10.3987/R-1983-04-0557  0.519
1983 Koskinen A, Lounasmaa M. Mild general synthesis of 4-substituted piperidines Journal of the Chemical Society, Chemical Communications. 821-822. DOI: 10.1039/C39830000821  0.566
1983 Koskinen A, Lounasmaa M. Novel applications of the modified polonovski reaction - V1 silyl enolates as nucleophilic alkylating reagents Tetrahedron Letters. 24: 1951-1952. DOI: 10.1016/S0040-4039(00)81814-6  0.553
1983 Koskinen A, Lounasmaa M. Regiospecific functionalisation of carbon atoms α to heterocyclic nitrogen Tetrahedron. 39: 1627-1633. DOI: 10.1016/S0040-4020(01)88573-2  0.524
1983 Suortti T, Koskinen A. Necatorin, a highly mutagenic compound from Lactarius necator Phytochemistry. 22: 2873-2874. DOI: 10.1016/S0031-9422(00)97723-9  0.325
1983 Koskinen A, Lounasmaa M. Mild General Synthesis Of 4-Substituted Piperidines Cheminform. 14. DOI: 10.1002/Chin.198349228  0.558
1982 Lounasmaa M, Koskinen A. A plausible biogenetic proposal for koumine. Planta Medica. 44: 120-1. PMID 17402092 DOI: 10.1055/S-2007-971416  0.437
1982 Koskinen A, Lounasmaa M. Biogenesis of the ajmaline type alkaloids. Planta Medica. 45: 248-9. PMID 17396924 DOI: 10.1055/S-2007-971385  0.444
1982 Koskinen A. 13C NMR Spectroscopy of Substituted Imidazoles Heterocycles. 19: 1633. DOI: 10.3987/R-1982-09-1633  0.369
1982 Lounasmaa M, Koskinen A. On the Structure of Ajmalinol Heterocycles. 19: 851. DOI: 10.3987/R-1982-05-0851  0.452
1982 Lounasmaa M, Koskinen A. Indoloquinolizidine synthesis. Stereochemistry and mechanism of cyclisation Tetrahedron Letters. 23: 1489-1492. DOI: 10.1016/S0040-4039(00)87140-3  0.567
1982 Lounasmaa M, Koskinen A. Novel applications of the modified polonovski reaction. A biomimetic synthesis of quinuclidines Tetrahedron Letters. 23: 349-352. DOI: 10.1016/S0040-4039(00)86828-8  0.574
1982 Lounasmaa M, Koskinen A. Novel Applications Of The Modified Polonovski Reaction. Ii. Regiocontrolled Iminium Ion Formation Cheminform. 14: 2115. DOI: 10.1002/Chin.198315236  0.49
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