| Year |
Citation |
Score |
| 2021 |
Gobeil SM, Bobay BG, Juvvadi PR, Cole DC, Heitman J, Steinbach WJ, Venters RA, Spicer LD. Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs. Mbio. e0300021. PMID 34809463 DOI: 10.1128/mBio.03000-21 |
0.595 |
|
| 2020 |
Juvvadi PR, Bobay BG, Gobeil SMC, Cole DC, Venters RA, Heitman J, Spicer LD, Steinbach WJ. FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus. Biochemical and Biophysical Research Communications. PMID 32192767 DOI: 10.1016/J.Bbrc.2020.03.062 |
0.585 |
|
| 2019 |
Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, et al. Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nature Communications. 10: 4275. PMID 31537789 DOI: 10.1038/S41467-019-12199-1 |
0.603 |
|
| 2019 |
Gobeil SMC, Ebert MCCJC, Park J, Gagné D, Doucet N, Berghuis AM, Pleiss J, Pelletier JN. The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Scientific Reports. 9: 6656. PMID 31040324 DOI: 10.1038/S41598-019-42866-8 |
0.675 |
|
| 2019 |
Gobeil SMC, Bobay BG, Spicer LD, Venters RA. N, C and H resonance assignments of FKBP12 proteins from the pathogenic fungi Mucor circinelloides and Aspergillus fumigatus. Biomolecular Nmr Assignments. PMID 30707421 DOI: 10.1007/S12104-019-09878-X |
0.604 |
|
| 2015 |
Gobeil SM, Gagné D, Doucet N, Pelletier JN. (15)N, (13)C and (1)H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant. Biomolecular Nmr Assignments. PMID 26386961 DOI: 10.1007/S12104-015-9645-8 |
0.663 |
|
| 2014 |
Gobeil SM, Clouthier CM, Park J, Gagné D, Berghuis AM, Doucet N, Pelletier JN. Maintenance of native-like protein dynamics may not be required for engineering functional proteins. Chemistry & Biology. 21: 1330-40. PMID 25200606 DOI: 10.1016/J.Chembiol.2014.07.016 |
0.673 |
|
| 2012 |
Clouthier CM, Morin S, Gobeil SM, Doucet N, Blanchet J, Nguyen E, Gagné SM, Pelletier JN. Chimeric β-lactamases: global conservation of parental function and fast time-scale dynamics with increased slow motions. Plos One. 7: e52283. PMID 23284969 DOI: 10.1371/Journal.Pone.0052283 |
0.661 |
|
| 2010 |
Morin S, Clouthier CM, Gobeil S, Pelletier JN, Gagné SM. Backbone resonance assignments of an artificially engineered TEM-1/PSE-4 Class A β-lactamase chimera. Biomolecular Nmr Assignments. 4: 127-30. PMID 20383614 DOI: 10.1007/S12104-010-9227-8 |
0.61 |
|
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