| Year |
Citation |
Score |
| 2025 |
Zhu J, Liang M, Sun K, Wei Y, Guo R, Zhang L, Shi J, Ma D, Hu Q, Huang G, Lu P. De novo design of transmembrane fluorescence-activating proteins. Nature. PMID 39972138 DOI: 10.1038/s41586-025-08598-8 |
0.423 |
|
| 2024 |
Lv X, Zhang Y, Sun K, Yang Q, Luo J, Tao L, Lu P. De novo design of mini-protein binders broadly neutralizing Clostridioides difficile toxin B variants. Nature Communications. 15: 8521. PMID 39358329 DOI: 10.1038/s41467-024-52582-1 |
0.316 |
|
| 2024 |
Sun K, Li S, Zheng B, Zhu Y, Wang T, Liang M, Yao Y, Zhang K, Zhang J, Li H, Han D, Zheng J, Coventry B, Cao L, Baker D, ... ... Lu P, et al. Accurate de novo design of heterochiral protein-protein interactions. Cell Research. PMID 39143121 DOI: 10.1038/s41422-024-01014-2 |
0.453 |
|
| 2024 |
Peruzzi JA, Gunnels TF, Edelstein HI, Lu P, Baker D, Leonard JN, Kamat NP. Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions. Nature Communications. 15: 5618. PMID 38965227 DOI: 10.1038/s41467-024-49678-z |
0.403 |
|
| 2024 |
Peruzzi JA, Steinkühler J, Vu TQ, Gunnels TF, Hu VT, Lu P, Baker D, Kamat NP. Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes. Nature Communications. 15: 3162. PMID 38605024 DOI: 10.1038/s41467-024-47163-1 |
0.459 |
|
| 2023 |
Höcker B, Lu P, Glasgow A, Marks DS, Chatterjee P, Slusky JSG, Schueler-Furman O, Huang P. How can the protein design community best support biologists who want to harness AI tools for protein structure prediction and design? Cell Systems. 14: 629-632. PMID 37591202 DOI: 10.1016/j.cels.2023.07.005 |
0.617 |
|
| 2022 |
Zhu J, Lu P. Computational design of transmembrane proteins. Current Opinion in Structural Biology. 74: 102381. PMID 35537282 DOI: 10.1016/j.sbi.2022.102381 |
0.441 |
|
| 2022 |
Zhou C, Lu P. De novo design of membrane transport proteins. Proteins. PMID 35305033 DOI: 10.1002/prot.26336 |
0.418 |
|
| 2021 |
Hosseinzadeh P, Watson PR, Craven TW, Li X, Rettie S, Pardo-Avila F, Bera AK, Mulligan VK, Lu P, Ford AS, Weitzner BD, Stewart LJ, Moyer AP, Di Piazza M, Whalen JG, et al. Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites. Nature Communications. 12: 3384. PMID 34099674 DOI: 10.1038/s41467-021-23609-8 |
0.4 |
|
| 2020 |
Xu C, Lu P, Gamal El-Din TM, Pei XY, Johnson MC, Uyeda A, Bick MJ, Xu Q, Jiang D, Bai H, Reggiano G, Hsia Y, Brunette TJ, Dou J, Ma D, et al. Computational design of transmembrane pores. Nature. PMID 32848250 DOI: 10.1038/S41586-020-2646-5 |
0.698 |
|
| 2019 |
Chen Z, Boyken SE, Jia M, Busch F, Flores-Solis D, Bick MJ, Lu P, VanAernum ZL, Sahasrabuddhe A, Langan RA, Bermeo S, Brunette TJ, Mulligan VK, Carter LP, DiMaio F, et al. Programmable design of orthogonal protein heterodimers. Nature. 565: 106-111. PMID 30568301 DOI: 10.1038/s41586-018-0802-y |
0.669 |
|
| 2018 |
Ma D, Wang Z, Merrikh CN, Lang KS, Lu P, Li X, Merrikh H, Rao Z, Xu W. Crystal structure of a membrane-bound O-acyltransferase. Nature. PMID 30283133 DOI: 10.1038/S41586-018-0568-2 |
0.458 |
|
| 2018 |
Jiang D, Gamal El-Din TM, Ing C, Lu P, Pomès R, Zheng N, Catterall WA. Structural basis for gating pore current in periodic paralysis. Nature. PMID 29769724 DOI: 10.1038/S41586-018-0120-4 |
0.315 |
|
| 2018 |
Lu P, Min D, DiMaio F, Wei KY, Vahey MD, Boyken SE, Chen Z, Fallas JA, Ueda G, Sheffler W, Mulligan VK, Xu W, Bowie JU, Baker D. Accurate computational design of multipass transmembrane proteins. Science (New York, N.Y.). 359: 1042-1046. PMID 29496880 DOI: 10.1126/Science.Aaq1739 |
0.668 |
|
| 2015 |
Bai XC, Yan C, Yang G, Lu P, Ma D, Sun L, Zhou R, Scheres SH, Shi Y. An atomic structure of human γ-secretase. Nature. 525: 212-7. PMID 26280335 DOI: 10.1038/Nature14892 |
0.493 |
|
| 2014 |
Xie T, Yan C, Zhou R, Zhao Y, Sun L, Yang G, Lu P, Ma D, Shi Y. Crystal structure of the γ-secretase component nicastrin. Proceedings of the National Academy of Sciences of the United States of America. 111: 13349-54. PMID 25197054 DOI: 10.1073/Pnas.1414837111 |
0.46 |
|
| 2014 |
Lu P, Bai XC, Ma D, Xie T, Yan C, Sun L, Yang G, Zhao Y, Zhou R, Scheres SH, Shi Y. Three-dimensional structure of human γ-secretase. Nature. 512: 166-70. PMID 25043039 DOI: 10.1038/Nature13567 |
0.503 |
|
| 2014 |
Lu P, Ma D, Yan C, Gong X, Du M, Shi Y. Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase. Proceedings of the National Academy of Sciences of the United States of America. 111: 1813-8. PMID 24449903 DOI: 10.1073/Pnas.1323931111 |
0.458 |
|
| 2013 |
Ma D, Lu P, Shi Y. Substrate selectivity of the acid-activated glutamate/γ-aminobutyric acid (GABA) antiporter GadC from Escherichia coli. The Journal of Biological Chemistry. 288: 15148-53. PMID 23589309 DOI: 10.1074/Jbc.M113.474502 |
0.41 |
|
| 2013 |
Lu P, Ma D, Chen Y, Guo Y, Chen GQ, Deng H, Shi Y. L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia. Cell Research. 23: 635-44. PMID 23337585 DOI: 10.1038/Cr.2013.13 |
0.381 |
|
| 2012 |
Ma D, Lu P, Yan C, Fan C, Yin P, Wang J, Shi Y. Structure and mechanism of a glutamate-GABA antiporter. Nature. 483: 632-6. PMID 22407317 DOI: 10.1038/Nature10917 |
0.459 |
|
| 2012 |
Huang W, Choi W, Hu W, Mi N, Guo Q, Ma M, Liu M, Tian Y, Lu P, Wang FL, Deng H, Liu L, Gao N, Yu L, Shi Y. Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein. Cell Research. 22: 473-89. PMID 22310240 DOI: 10.1038/Cr.2012.24 |
0.542 |
|
| 2009 |
Wang Y, Huang Y, Wang J, Cheng C, Huang W, Lu P, Xu YN, Wang P, Yan N, Shi Y. Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature. 462: 467-72. PMID 19940917 DOI: 10.1038/Nature08610 |
0.572 |
|
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