| Year |
Citation |
Score |
| 2023 |
Bilget Guven E, Durmaz Sahin I, Altiparmak D, Servili B, Essiz S, Cetin-Atalay R, Tuncbilek M. Newly synthesized 6-substituted piperazine/phenyl-9-cyclopentyl containing purine nucleobase analogs act as potent anticancer agents and induce apoptosis inhibiting Src in hepatocellular carcinoma cells. Rsc Medicinal Chemistry. 14: 2658-2676. PMID 38107180 DOI: 10.1039/d3md00440f |
0.418 |
|
| 2023 |
Hawash M, Ergun SG, Kahraman DC, Olgac A, Hamel E, Cetin-Atalay R, Baytas SN. Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies. Journal of Molecular Structure. 1285. PMID 37234266 DOI: 10.1016/j.molstruc.2023.135477 |
0.735 |
|
| 2022 |
Turanlı S, Nalbat E, Lengerli D, İbiş K, Güntekin Ergün S, Akhan Güzelcan E, Muyan M, Cetin-Atalay R, Çalışkan B, Banoglu E. Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with Growth Inhibitory and Antitumor Activity. Acs Omega. 7: 36206-36226. PMID 36278052 DOI: 10.1021/acsomega.2c03405 |
0.417 |
|
| 2021 |
Hawash M, Kahraman DC, Ergun SG, Cetin-Atalay R, Baytas SN. Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines. Bmc Chemistry. 15: 66. PMID 34930409 DOI: 10.1186/s13065-021-00793-8 |
0.719 |
|
| 2021 |
İbiş K, Nalbat E, Çalışkan B, Kahraman DC, Cetin-Atalay R, Banoglu E. Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells. European Journal of Medicinal Chemistry. 221: 113489. PMID 33951549 DOI: 10.1016/j.ejmech.2021.113489 |
0.421 |
|
| 2021 |
Hawash M, Kahraman DC, Cetin-Atalay R, Baytas S. Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation. Chemistry & Biodiversity. PMID 33713038 DOI: 10.1002/cbdv.202001037 |
0.73 |
|
| 2020 |
Sahin ID, Christodoulou MS, Guzelcan EA, Koyas A, Karaca C, Passarella D, Cetin-Atalay R. A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition. Scientific Reports. 10: 11814. PMID 32678233 DOI: 10.1038/S41598-020-68775-9 |
0.485 |
|
| 2019 |
Ozgencil F, Eren G, Ozkan Y, Guntekin-Ergun S, Cetin-Atalay R. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorganic & Medicinal Chemistry. 115217. PMID 31818629 DOI: 10.1016/J.Bmc.2019.115217 |
0.386 |
|
| 2019 |
Eren G, Bruno A, Guntekin-Ergun S, Cetin-Atalay R, Ozgencil F, Ozkan Y, Gozelle M, Kaya SG, Costantino G. Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors. Journal of Molecular Graphics & Modelling. 89: 60-73. PMID 30870650 DOI: 10.1016/J.Jmgm.2019.02.014 |
0.419 |
|
| 2019 |
Güzelcan EA, Baxendale IR, Cetin-Atalay R, Baumann M. Synthesis of new derivatives of boehmeriasin A and their biological evaluation in liver cancer. European Journal of Medicinal Chemistry. 166: 243-255. PMID 30716712 DOI: 10.1016/J.Ejmech.2019.01.056 |
0.487 |
|
| 2018 |
Türe A, Kahraman DC, Cetin-Atalay R, Helvacıoğlu S, Charehsaz M, Küçükgüzel İ. Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine-(thio)urea hybrids as potential kinase inhibitors. Computational Biology and Chemistry. 78: 227-241. PMID 30579980 DOI: 10.1016/J.Compbiolchem.2018.12.003 |
0.525 |
|
| 2018 |
Inceler N, Ozkan Y, Turan NN, Kahraman DC, Cetin-Atalay R, Baytas SN. Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents. Medchemcomm. 9: 795-811. PMID 30108969 DOI: 10.1039/C8Md00022K |
0.711 |
|
| 2018 |
Rifaioglu AS, Atas H, Martin MJ, Cetin-Atalay R, Atalay V, Dogan T. Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases. Briefings in Bioinformatics. PMID 30084866 DOI: 10.1093/Bib/Bby061 |
0.304 |
|
| 2018 |
Tuncbilek M, Kucukdumlu A, Guven EB, Altiparmak D, Cetin-Atalay R. Synthesis of novel 6-substituted amino-9-(β-d-ribofuranosyl)purine analogs and their bioactivities on human epithelial cancer cells. Bioorganic & Medicinal Chemistry Letters. PMID 29326016 DOI: 10.1016/J.Bmcl.2017.12.070 |
0.498 |
|
| 2018 |
Çevik D, Yılmazgöz ŞB, Kan Y, Güzelcan EA, Durmaz I, Çetin-Atalay R, Kırmızıbekmez H. Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action Industrial Crops and Products. 124: 389-396. DOI: 10.1016/J.Indcrop.2018.08.014 |
0.446 |
|
| 2018 |
Kucukoglu K, Gul M, Gul HI, Cetin-Atalay R, Geny B. Cytotoxicities of novel hydrazone compounds with pyrrolidine moiety: inhibition of mitochondrial respiration may be a possible mechanism of action for the cytotoxicity of new hydrazones Medicinal Chemistry Research. 27: 2116-2124. DOI: 10.1007/S00044-018-2220-Y |
0.421 |
|
| 2017 |
Kahraman DC, Hanquet G, Jeanmart L, Lanners S, Šramel P, Boháč A, Cetin-Atalay R. Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells. Medchemcomm. 8: 81-87. PMID 30108693 DOI: 10.1039/C6Md00392C |
0.421 |
|
| 2017 |
Aichinger W, Krappe S, Cetin AE, Cetin-Atalay R, Üner A, Benz M, Wittenberg T, Stamminger M, Münzenmayer C. Automated cancer stem cell recognition in H and E stained tissue using convolutional neural networks and color deconvolution Proceedings of Spie. 10140. DOI: 10.1117/12.2254036 |
0.311 |
|
| 2016 |
Durmaz I, Guven EB, Ersahin T, Ozturk M, Calis I, Cetin-Atalay R. Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 23: 42-51. PMID 26902406 DOI: 10.1016/J.Phymed.2015.11.012 |
0.412 |
|
| 2016 |
Mumcuoglu M, Gurkan-Alp AS, Buyukbingol E, Cetin-Atalay R. Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells. Steroids. 108: 31-8. PMID 26898539 DOI: 10.1016/J.Steroids.2016.02.008 |
0.399 |
|
| 2016 |
Aytaç PS, Durmaz I, Houston DR, Çetin-Atalay R, Tozkoparan B. Novel triazolothiadiazines act as potent anticancer agents in liver cancer cells through Akt and ASK-1 proteins. Bioorganic & Medicinal Chemistry. 24: 858-72. PMID 26810835 DOI: 10.1016/J.Bmc.2016.01.013 |
0.498 |
|
| 2016 |
Kucukoglu K, Gul HI, Gul M, Cetin-Atalay R, Baratli Y, Geny B. Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration Letters in Drug Design & Discovery. 13: 734-741. DOI: 10.2174/1570180813666160113002907 |
0.318 |
|
| 2016 |
Çinar U, Çetin YY, Çetin-Atalay R, Çetin AE. Classification of human carcinoma cells using multispectral imagery Proceedings of Spie. 9791: 1-6. DOI: 10.1117/12.2217022 |
0.341 |
|
| 2015 |
Stucchi M, Cairati S, Cetin-Atalay R, Christodoulou MS, Grazioso G, Pescitelli G, Silvani A, Yildirim DC, Lesma G. Application of the Ugi reaction with multiple amino acid-derived components: synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics. Organic & Biomolecular Chemistry. 13: 4993-5005. PMID 25821154 DOI: 10.1039/C5Ob00218D |
0.327 |
|
| 2015 |
Ç?kla-Süzgün P, Kaushik-Basu N, Basu A, Arora P, Talele TT, Durmaz I, Çetin-Atalay R, Küçükgüzel ?G. Anti-cancer and anti-hepatitis C virus NS5B polymerase activity of etodolac 1,2,4-triazoles. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-8. PMID 25676325 DOI: 10.3109/14756366.2014.971780 |
0.444 |
|
| 2015 |
Gurdal EE, Buclulgan E, Durmaz I, Cetin-Atalay R, Yarim M. Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives. Anti-Cancer Agents in Medicinal Chemistry. 15: 382-9. PMID 25511511 DOI: 10.2174/1871520615666141216151101 |
0.523 |
|
| 2015 |
Gurdal EE, Durmaz I, Cetin-Atalay R, Yarim M. Cytotoxic activities of some benzothiazole-piperazine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry. 30: 649-54. PMID 25333766 DOI: 10.3109/14756366.2014.959513 |
0.525 |
|
| 2015 |
Kucukoglu K, Mete E, Cetin-Atalay R, Gul HI. Synthesis of 3-aroyl-4-aryl-1-isopropylamino-4-piperidinols and evaluation of the cytotoxicities of the compounds against human hepatoma and breast cancer cell lines. Journal of Enzyme Inhibition and Medicinal Chemistry. 30: 564-8. PMID 25198889 DOI: 10.3109/14756366.2014.951350 |
0.43 |
|
| 2015 |
Önen-Bayram FE, Buran K, Durmaz I, Berk B, Cetin-Atalay R. 3-Propionyl-thiazolidine-4-carboxylic acid ethyl esters: a family of antiproliferative thiazolidines Medchemcomm. 6: 90-93. DOI: 10.1039/C4Md00306C |
0.389 |
|
| 2015 |
Ersahin T, Tuncbag N, Acar A, Cetin-Atalay R. P0402 : Combination therapy for hepatocellular carcinoma: A systems biology perspective on the synergistic antitumor activity of sorafenib with PI3K/AKT pathway inhibitors Journal of Hepatology. 62: S464. DOI: 10.1016/S0168-8278(15)30614-0 |
0.324 |
|
| 2014 |
Gurdal EE, Durmaz I, Cetin-Atalay R, Yarim M. Synthesis and cytotoxicity studies of novel benzhydrylpiperazine carboxamide and thioamide derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry. 29: 205-14. PMID 23391169 DOI: 10.3109/14756366.2013.765416 |
0.481 |
|
| 2014 |
Gezici O, Durmaz I, Bilget Güven E, Ünal O, Özgün A, Cetin-Atalay R, Tuncel D. Dual functionality of conjugated polymer nanoparticles as an anticancer drug carrier and a fluorescent probe for cell imaging Rsc Advances. 4: 1302-1309. DOI: 10.1039/C3Ra45120H |
0.382 |
|
| 2013 |
Simioni C, Martelli AM, Cani A, Cetin-Atalay R, McCubrey JA, Capitani S, Neri LM. The AKT inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated AKT-1 and synergizes with conventional chemotherapy. Oncotarget. 4: 1496-506. PMID 24036604 DOI: 10.18632/Oncotarget.1236 |
0.393 |
|
| 2013 |
Yildiz G, Arslan-Ergul A, Bagislar S, Konu O, Yuzugullu H, Gursoy-Yuzugullu O, Ozturk N, Ozen C, Ozdag H, Erdal E, Karademir S, Sagol O, Mizrak D, Bozkaya H, Ilk HG, ... ... Cetin-Atalay R, et al. Genome-wide transcriptional reorganization associated with senescence-to-immortality switch during human hepatocellular carcinogenesis. Plos One. 8: e64016. PMID 23691139 DOI: 10.1371/Journal.Pone.0064016 |
0.331 |
|
| 2013 |
Gurdal EE, Yarim M, Durmaz I, Cetin-Atalay R. Cytotoxic activities of some novel benzhydrylpiperazine derivatives. Drug Research. 63: 121-8. PMID 23447090 DOI: 10.1055/s-0032-1333275 |
0.396 |
|
| 2013 |
Keskin F, Suhre A, Kose K, Ersahin T, Cetin AE, Cetin-Atalay R. Image classification of human carcinoma cells using complex wavelet-based covariance descriptors. Plos One. 8: e52807. PMID 23341908 DOI: 10.1371/Journal.Pone.0052807 |
0.415 |
|
| 2012 |
Gurkan-Alp AS, Mumcuoglu M, Andac CA, Dayanc E, Cetin-Atalay R, Buyukbingol E. Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives. European Journal of Medicinal Chemistry. 58: 346-54. PMID 23142674 DOI: 10.1016/J.Ejmech.2012.10.013 |
0.471 |
|
| 2012 |
Onen-Bayram FE, Durmaz I, Scherman D, Herscovici J, Cetin-Atalay R. A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells. Bioorganic & Medicinal Chemistry. 20: 5094-102. PMID 22867707 DOI: 10.1016/J.Bmc.2012.07.016 |
0.508 |
|
| 2012 |
Koksal M, Yarim M, Durmaz I, Cetin-Atalay R. Synthesis and cytotoxic activity of novel 3-methyl-1-[(4-substitutedpiperazin-1-yl)methyl]-1H-indole derivatives. Arzneimittel-Forschung. 62: 389-94. PMID 22753155 DOI: 10.1055/S-0032-1314868 |
0.412 |
|
| 2011 |
Mete E, Gul HI, Cetin-Atalay R, Das U, Sahin E, Gul M, Kazaz C, Dimmock JR. The design and cytotoxic evaluation of some 1-aryl-3-isopropylamino-1-propanone hydrochlorides towards human Huh-7 hepatoma cells. Archiv Der Pharmazie. 344: 333-9. PMID 21319206 DOI: 10.1002/Ardp.201000194 |
0.471 |
|
| 2011 |
Buontempo F, Ersahin T, Missiroli S, Senturk S, Etro D, Ozturk M, Capitani S, Cetin-Atalay R, Neri ML. Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status. Investigational New Drugs. 29: 1303-13. PMID 20628892 DOI: 10.1007/S10637-010-9486-3 |
0.423 |
|
| 2009 |
Sayan B, Emre NC, Irmak MB, Ozturk M, Cetin-Atalay R. Nuclear exclusion of p33ING1b tumor suppressor protein: explored in HCC cells using a new highly specific antibody. Hybridoma (2005). 28: 1-6. PMID 19132896 DOI: 10.1089/Hyb.2008.0058 |
0.386 |
|
| 2006 |
Ozturk N, Erdal E, Mumcuoglu M, Akcali KC, Yalcin O, Senturk S, Arslan-Ergul A, Gur B, Yulug I, Cetin-Atalay R, Yakicier C, Yagci T, Tez M, Ozturk M. Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 2178-83. PMID 16461895 DOI: 10.1073/Pnas.0510877103 |
0.367 |
|
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