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Laurent Lacroix - Publications

Affiliations: 
2001- Paris INSERM, Rennes, Bretagne, France 
Area:
i-motif, G-quadruplex, telomere, replication
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Esnault C, Magat T, Zine El Aabidine A, Garcia-Oliver E, Cucchiarini A, Bouchouika S, Lleres D, Goerke L, Luo Y, Verga D, Lacroix L, Feil R, Spicuglia S, Mergny JL, Andrau JC. G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions. Nature Genetics. PMID 37400615 DOI: 10.1038/s41588-023-01437-4  0.69
2022 Luo Y, Granzhan A, Marquevielle J, Cucchiarini A, Lacroix L, Amrane S, Verga D, Mergny JL. Guidelines for G-quadruplexes: I. In vitro characterization. Biochimie. PMID 36596406 DOI: 10.1016/j.biochi.2022.12.019  0.708
2021 Cheng M, Qiu D, Tamon L, Ištvánková E, Víšková P, Amrane S, Guédin A, Chen J, Lacroix L, Ju H, Trantírek L, Sahakyan AB, Zhou J, Mergny JL. Thermal and pH stabilities of i-DNA: confronting in vitro experiments with models and in-cell NMR data. Angewandte Chemie (International Ed. in English). PMID 33605024 DOI: 10.1002/anie.202016801  0.69
2020 Gazanion E, Lacroix L, Alberti P, Gurung P, Wein S, Cheng M, Mergny JL, Gomes AR, Lopez-Rubio JJ. Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. Plos Genetics. 16: e1008917. PMID 32628663 DOI: 10.1371/journal.pgen.1008917  0.664
2020 Prorok P, Artufel M, Aze A, Coulombe P, Peiffer I, Lacroix L, Guédin A, Mergny JL, Damaschke J, Schepers A, Cayrou C, Teulade-Fichou MP, Ballester B, Méchali M. Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity. Nature Communications. 11: 3058. PMID 32528032 DOI: 10.1038/S41467-020-16122-X  0.66
2019 Prorok P, Artufel M, Aze A, Coulombe P, Peiffer I, Lacroix L, Guédin A, Mergny JL, Damaschke J, Schepers A, Ballester B, Méchali M. Involvement of G-quadruplex regions in mammalian replication origin activity. Nature Communications. 10: 3274. PMID 31332171 DOI: 10.1038/S41467-019-11104-0  0.726
2019 Saad M, Guédin A, Amor S, Bedrat A, Tourasse NJ, Fayyad-Kazan H, Pratviel G, Lacroix L, Mergny JL. Mapping and characterization of G-quadruplexes in the genome of the social amoeba Dictyostelium discoideum. Nucleic Acids Research. PMID 30923812 DOI: 10.1093/Nar/Gkz196  0.695
2018 Guédin A, Lin LY, Armane S, Lacroix L, Mergny JL, Thore S, Yatsunyk LA. Quadruplexes in 'Dicty': crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome. Nucleic Acids Research. PMID 29718337 DOI: 10.1093/Nar/Gky290  0.709
2016 Bedrat A, Lacroix L, Mergny JL. Re-evaluation of G-quadruplex propensity with G4Hunter. Nucleic Acids Research. 44: 1746-59. PMID 26792894 DOI: 10.1093/Nar/Gkw006  0.699
2011 Lacroix L, Séosse A, Mergny JL. Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands. Nucleic Acids Research. 39: e21. PMID 21106496 DOI: 10.1093/Nar/Gkq1199  0.708
2010 Lim KW, Lacroix L, Yue DJ, Lim JK, Lim JM, Phan AT. Coexistence of two distinct G-quadruplex conformations in the hTERT promoter. Journal of the American Chemical Society. 132: 12331-42. PMID 20704263 DOI: 10.1021/ja101252n  0.442
2010 Guédin A, Lacroix L, Mergny JL. Thermal melting studies of ligand DNA interactions. Methods in Molecular Biology (Clifton, N.J.). 613: 25-35. PMID 19997875 DOI: 10.1007/978-1-60327-418-0_2  0.633
2009 Lim KW, Alberti P, Guédin A, Lacroix L, Riou JF, Royle NJ, Mergny JL, Phan AT. Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad. Nucleic Acids Research. 37: 6239-48. PMID 19692585 DOI: 10.1093/Nar/Gkp630  0.699
2009 Mergny JL, Lacroix L. UV Melting of G-Quadruplexes. Current Protocols in Nucleic Acid Chemistry. Unit 17.1. PMID 19488970 DOI: 10.1002/0471142700.Nc1701S37  0.647
2008 Lyonnais S, Piétrement O, Chepelianski A, Guéron S, Lacroix L, Le Cam E, Mergny JL. Functionalization of DNA G-Wires for patterning and nanofabrication. Nucleic Acids Symposium Series (2004). 689-90. PMID 18776567 DOI: 10.1093/nass/nrn348  0.695
2008 De Cian A, Gros J, Guédin A, Haddi M, Lyonnais S, Guittat L, Riou JF, Trentesaux C, Saccà B, Lacroix L, Alberti P, Mergny JL. DNA and RNA quadruplex ligands. Nucleic Acids Symposium Series (2004). 7-8. PMID 18776226 DOI: 10.1093/nass/nrn004  0.713
2008 Gros J, Guédin A, Mergny JL, Lacroix L. G-quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC Chembiochem. 9: 2075-2079. PMID 18683270 DOI: 10.1002/Cbic.200800300  0.65
2008 Gros J, Aviñó A, Lopez de la Osa J, González C, Lacroix L, Pérez A, Orozco M, Eritja R, Mergny JL. 8-Amino guanine accelerates tetramolecular G-quadruplex formation. Chemical Communications (Cambridge, England). 2926-8. PMID 18566727 DOI: 10.1039/B801221K  0.671
2008 Monchaud D, Yang P, Lacroix L, Teulade-Fichou MP, Mergny JL. A metal-mediated conformational switch controls G-quadruplex binding affinity. Angewandte Chemie (International Ed. in English). 47: 4858-61. PMID 18496803 DOI: 10.1002/Anie.200800468  0.617
2008 Guédin A, De Cian A, Gros J, Lacroix L, Mergny JL. Sequence effects in single-base loops for quadruplexes. Biochimie. 90: 686-96. PMID 18294461 DOI: 10.1016/J.Biochi.2008.01.009  0.673
2008 De Cian A, Lacroix L, Douarre C, Temime-Smaali N, Trentesaux C, Riou JF, Mergny JL. Targeting telomeres and telomerase. Biochimie. 90: 131-55. PMID 17822826 DOI: 10.1016/J.Biochi.2007.07.011  0.619
2007 De Cian A, Cristofari G, Reichenbach P, De Lemos E, Monchaud D, Teulade-Fichou MP, Shin-Ya K, Lacroix L, Lingner J, Mergny JL. Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proceedings of the National Academy of Sciences of the United States of America. 104: 17347-52. PMID 17954919 DOI: 10.1073/Pnas.0707365104  0.641
2007 Mergny JL, Lacroix L, Riou JF. Telomerase: a dimeric ménage à trois. Chembiochem : a European Journal of Chemical Biology. 8: 1483-5. PMID 17625802 DOI: 10.1002/Cbic.200700272  0.579
2007 De Cian A, Guittat L, Kaiser M, Saccà B, Amrane S, Bourdoncle A, Alberti P, Teulade-Fichou MP, Lacroix L, Mergny JL. Fluorescence-based melting assays for studying quadruplex ligands. Methods (San Diego, Calif.). 42: 183-95. PMID 17472900 DOI: 10.1016/J.Ymeth.2006.10.004  0.693
2007 Gros J, Rosu F, Amrane S, De Cian A, Gabelica V, Lacroix L, Mergny JL. Guanines are a quartet's best friend: Impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes Nucleic Acids Research. 35: 3064-3075. PMID 17452368 DOI: 10.1093/Nar/Gkm111  0.685
2006 Alberti P, Bourdoncle A, Saccà B, Lacroix L, Mergny JL. DNA nanomachines and nanostructures involving quadruplexes. Organic & Biomolecular Chemistry. 4: 3383-91. PMID 17036128 DOI: 10.1039/B605739J  0.698
2006 Bourdoncle A, Estévez Torres A, Gosse C, Lacroix L, Vekhoff P, Le Saux T, Jullien L, Mergny JL. Quadruplex-based molecular beacons as tunable DNA probes. Journal of the American Chemical Society. 128: 11094-105. PMID 16925427 DOI: 10.1021/Ja0608040  0.447
2006 Luu KN, Phan AT, Kuryavyi V, Lacroix L, Patel DJ. Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold. Journal of the American Chemical Society. 128: 9963-70. PMID 16866556 DOI: 10.1021/Ja062791W  0.362
2005 Gros J, Webba da Silva M, De Cian A, Amrane S, Rosu F, Bourdoncle A, Saccà B, Alberti P, Lacroix L, Mergny JL. Kinetics and thermodynamics of G-quadruplexes. Nucleic Acids Symposium Series (2004). 61-2. PMID 17150633 DOI: 10.1093/nass/49.1.61  0.714
2005 Mergny JL, Li J, Lacroix L, Amrane S, Chaires JB. Thermal difference spectra: a specific signature for nucleic acid structures. Nucleic Acids Research. 33: e138. PMID 16157860 DOI: 10.1093/Nar/Gni134  0.623
2005 Saccà B, Lacroix L, Mergny JL. The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides. Nucleic Acids Research. 33: 1182-92. PMID 15731338 DOI: 10.1093/Nar/Gki257  0.682
2005 Mergny JL, De Cian A, Ghelab A, Saccà B, Lacroix L. Kinetics of tetramolecular quadruplexes. Nucleic Acids Research. 33: 81-94. PMID 15642696 DOI: 10.1093/Nar/Gki148  0.673
2005 Mergny JL, Li J, Lacroix L, Amrane S, Chaires JB. Thermal difference spectra: A specific signature for nucleic acid structures Nucleic Acids Research. 33: 1-6. DOI: 10.1093/nar/gni134  0.581
2004 Guittat L, Alberti P, Gomez D, De Cian A, Pennarun G, Lemarteleur T, Belmokhtar C, Paterski R, Morjani H, Trentesaux C, Mandine E, Boussin F, Mailliet P, Lacroix L, Riou JF, et al. Targeting human telomerase for cancer therapeutics. Cytotechnology. 45: 75-90. PMID 19003245 DOI: 10.1007/S10616-004-5127-Z  0.622
2004 Horn V, Lacroix L, Gautier T, Takasugi M, Mergny JL, Lacoste J. Triple helix formation with Drosophila satellite repeats. Unexpected stabilization by copper ions. Biochemistry. 43: 11196-205. PMID 15366929 DOI: 10.1021/Bi049287T  0.65
2004 Gomez D, Lemarteleur T, Lacroix L, Mailliet P, Mergny JL, Riou JF. Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing. Nucleic Acids Research. 32: 371-9. PMID 14729921 DOI: 10.1093/Nar/Gkh181  0.662
2003 Mergny JL, Lacroix L. Analysis of thermal melting curves. Oligonucleotides. 13: 515-37. PMID 15025917 DOI: 10.1089/154545703322860825  0.648
2003 Gomez D, Aouali N, Londoño-Vallejo A, Lacroix L, Mégnin-Chanet F, Lemarteleur T, Douarre C, Shin-ya K, Mailliet P, Trentesaux C, Morjani H, Mergny JL, Riou JF. Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration. The Journal of Biological Chemistry. 278: 50554-62. PMID 14525974 DOI: 10.1074/Jbc.M308440200  0.653
2003 Rosu F, De Pauw E, Guittat L, Alberti P, Lacroix L, Mailliet P, Riou JF, Mergny JL. Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis. Biochemistry. 42: 10361-71. PMID 12950163 DOI: 10.1021/Bi034531M  0.67
2003 Alberti P, Lacroix L, Guittat L, Hélène C, Mergny JL. Nucleic acids as targets for antitelomerase agents. Mini Reviews in Medicinal Chemistry. 3: 23-36. PMID 12570852 DOI: 10.2174/1389557033405485  0.623
2002 Mills M, Lacroix L, Arimondo PB, Leroy JL, François JC, Klump H, Mergny JL. Unusual DNA conformations: Implications for telomeres Current Medicinal Chemistry - Anti-Cancer Agents. 2: 627-644. PMID 12678729 DOI: 10.2174/1568011023353877  0.715
2002 Mills M, Arimondo PB, Lacroix L, Garestier T, Klump H, Mergny JL. Chemical modification of the third strand: differential effects on purine and pyrimidine triple helix formation. Biochemistry. 41: 357-66. PMID 11772035 DOI: 10.1021/Bi011122M  0.676
2001 Mergny JL, Lacroix L, Teulade-Fichou MP, Hounsou C, Guittat L, Hoarau M, Arimondo PB, Vigneron JP, Lehn JM, Riou JF, Garestier T, Hélène C. Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proceedings of the National Academy of Sciences of the United States of America. 98: 3062-7. PMID 11248032 DOI: 10.1073/Pnas.051620698  0.703
2000 Lacroix L, Mergny JL. Chemical modification of pyrimidine TFOs: effect on i-motif and triple helix formation. Archives of Biochemistry and Biophysics. 381: 153-63. PMID 11019831 DOI: 10.1006/Abbi.2000.1934  0.686
2000 Lacroix L, Arimondo PB, Takasugi M, Hélène C, Mergny JL. Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions. Biochemical and Biophysical Research Communications. 270: 363-9. PMID 10753631 DOI: 10.1006/Bbrc.2000.2438  0.656
2000 Lacroix L, Liénard H, Labourier E, Djavaheri-Mergny M, Lacoste J, Leffers H, Tazi J, Hélène C, Mergny JL. Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro. Nucleic Acids Research. 28: 1564-75. PMID 10710423 DOI: 10.1093/Nar/28.7.1564  0.648
2000 François JC, Lacoste J, Lacroix L, Mergny JL. Design of antisense and triplex-forming oligonucleotides. Methods in Enzymology. 313: 74-95. PMID 10595350 DOI: 10.1016/S0076-6879(00)13006-X  0.66
1999 Mills M, Arimondo PB, Lacroix L, Garestier T, Hélène C, Klump H, Mergny JL. Energetics of strand-displacement reactions in triple helices: a spectroscopic study. Journal of Molecular Biology. 291: 1035-54. PMID 10518941 DOI: 10.1006/Jmbi.1999.3014  0.662
1999 Lacroix L, Lacoste J, Reddoch JF, Mergny JL, Levy DD, Seidman MM, Matteucci MD, Glazer PM. Triplex formation by oligonucleotides containing 5-(1-propynyl)-2'-deoxyuridine: decreased magnesium dependence and improved intracellular gene targeting. Biochemistry. 38: 1893-901. PMID 10026270 DOI: 10.1021/Bi982290Q  0.726
1998 Mergny JL, Phan AT, Lacroix L. Following G-quartet formation by UV-spectroscopy. Febs Letters. 435: 74-8. PMID 9755862 DOI: 10.1016/S0014-5793(98)01043-6  0.656
1998 Raha M, Lacroix L, Glazer PM. Mutagenesis Mediated by Triple Helix–Forming Oligonucleotides Conjugated to Psoralen: Effects of Linker Arm Length and Sequence Context Photochemistry and Photobiology. 67: 289-294. DOI: 10.1111/J.1751-1097.1998.Tb05201.X  0.545
1996 Lacroix L, Mergny JL, Leroy JL, Hélène C. Inability of RNA to form the i-motif: implications for triplex formation. Biochemistry. 35: 8715-22. PMID 8679634 DOI: 10.1021/Bi960107S  0.695
1995 Mergny JL, Lacroix L, Han X, Leroy JL, Hélène C. Intramolecular folding of pyrimidine oligodeoxynucleotides into an i-DNA motif Journal of the American Chemical Society. 117: X-8898. DOI: 10.1021/Ja00140A001  0.65
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