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Geoffrey M. Cooper - Publications

Affiliations: 
Biology Boston University, Boston, MA, United States 
Area:
Cancer Research
Website:
http://www.bu.edu/biology/people/faculty/cooper/

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Adams KW, Kletsov S, Lamm RJ, Elman JS, Mullenbrock S, Cooper GM. Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells. Plos One. 12: e0170076. PMID 28076410 DOI: 10.1371/journal.pone.0170076  0.8
2012 Nayak G, Cooper GM. p53 is a major component of the transcriptional and apoptotic program regulated by PI 3-kinase/Akt/GSK3 signaling. Cell Death & Disease. 3: e400. PMID 23059819 DOI: 10.1038/cddis.2012.138  0.8
2011 Mullenbrock S, Shah J, Cooper GM. Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell differentiation. The Journal of Biological Chemistry. 286: 45131-45. PMID 22065583 DOI: 10.1074/jbc.M111.274076  0.8
2011 Tullai JW, Graham JR, Cooper GM. A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells. Cell Cycle (Georgetown, Tex.). 10: 3072-7. PMID 21900749 DOI: 10.4161/cc.10.18.17321  0.8
2011 Terragni J, Nayak G, Banerjee S, Medrano JL, Graham JR, Brennan JF, Sepulveda S, Cooper GM. The E-box binding factors Max/Mnt, MITF, and USF1 act coordinately with FoxO to regulate expression of proapoptotic and cell cycle control genes by phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3 signaling. The Journal of Biological Chemistry. 286: 36215-27. PMID 21873430 DOI: 10.1074/jbc.M111.246116  0.8
2011 Tullai JW, Tacheva S, Owens LJ, Graham JR, Cooper GM. AP-1 is a component of the transcriptional network regulated by GSK-3 in quiescent cells. Plos One. 6: e20150. PMID 21647439 DOI: 10.1371/journal.pone.0020150  0.8
2010 Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, Batzoglou S. Identifying a high fraction of the human genome to be under selective constraint using GERP++. Plos Computational Biology. 6: e1001025. PMID 21152010 DOI: 10.1371/journal.pcbi.1001025  0.32
2010 Graham JR, Hendershott MC, Terragni J, Cooper GM. mRNA degradation plays a significant role in the program of gene expression regulated by phosphatidylinositol 3-kinase signaling. Molecular and Cellular Biology. 30: 5295-305. PMID 20855526 DOI: 10.1128/MCB.00303-10  0.8
2010 Ng SB, Bigham AW, Buckingham KJ, Hannibal MC, McMillin MJ, Gildersleeve HI, Beck AE, Tabor HK, Cooper GM, Mefford HC, Lee C, Turner EH, Smith JD, Rieder MJ, Yoshiura K, et al. Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nature Genetics. 42: 790-3. PMID 20711175 DOI: 10.1038/ng.646  0.32
2010 Saxena UH, Owens L, Graham JR, Cooper GM, Hansen U. Prolyl isomerase Pin1 regulates transcription factor LSF (TFCP2) by facilitating dephosphorylation at two serine-proline motifs. The Journal of Biological Chemistry. 285: 31139-47. PMID 20682773 DOI: 10.1074/jbc.M109.078808  0.8
2010 Cooper GM, Goode DL, Ng SB, Sidow A, Bamshad MJ, Shendure J, Nickerson DA. Single-nucleotide evolutionary constraint scores highlight disease-causing mutations. Nature Methods. 7: 250-1. PMID 20354513 DOI: 10.1038/nmeth0410-250  0.32
2010 Goode DL, Cooper GM, Schmutz J, Dickson M, Gonzales E, Tsai M, Karra K, Davydov E, Batzoglou S, Myers RM, Sidow A. Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes. Genome Research. 20: 301-10. PMID 20067941 DOI: 10.1101/gr.102210.109  0.32
2010 Graham JR, Tullai JW, Cooper GM. GSK-3 represses growth factor-inducible genes by inhibiting NF-κB in quiescent cells Journal of Biological Chemistry. 285: 4472-4480. PMID 20018891 DOI: 10.1074/jbc.M109.053785  0.8
2009 Saxena UH, Powell CM, Fecko JK, Cacioppo R, Chou HS, Cooper GM, Hansen U. Phosphorylation by cyclin C/cyclin-dependent kinase 2 following mitogenic stimulation of murine fibroblasts inhibits transcriptional activity of LSF during G1 progression. Molecular and Cellular Biology. 29: 2335-45. PMID 19237534 DOI: 10.1128/MCB.00687-08  0.8
2008 Cooper GM, Johnson JA, Langaee TY, Feng H, Stanaway IB, Schwarz UI, Ritchie MD, Stein CM, Roden DM, Smith JD, Veenstra DL, Rettie AE, Rieder MJ. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood. 112: 1022-7. PMID 18535201 DOI: 10.1182/blood-2008-01-134247  0.32
2008 Reiner AP, Barber MJ, Guan Y, Ridker PM, Lange LA, Chasman DI, Walston JD, Cooper GM, Jenny NS, Rieder MJ, Durda JP, Smith JD, Novembre J, Tracy RP, Rotter JI, et al. Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. American Journal of Human Genetics. 82: 1193-201. PMID 18439552 DOI: 10.1016/j.ajhg.2008.03.017  0.32
2008 Cooper GM, Brown CD. Qualifying the relationship between sequence conservation and molecular function. Genome Research. 18: 201-5. PMID 18245453 DOI: 10.1101/gr.7205808  0.32
2008 Terragni J, Graham JR, Adams KW, Schaffer ME, Tullai JW, Cooper GM. Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors. Bmc Cell Biology. 9: 6. PMID 18226221 DOI: 10.1186/1471-2121-9-6  0.8
2008 Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ, Cooper GM, Roos C, Voight BF, Havulinna AS, Wahlstrand B, Hedner T, Corella D, Tai ES, Ordovas JM, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nature Genetics. 40: 189-97. PMID 18193044 DOI: 10.1038/ng.75  0.32
2008 Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ, Cooper GM, Roos C, Voight BF, Havulinna AS, Wahlstrand B, Hedner T, Corella D, Tai ES, Ordovas JM, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans (Nature Genetics (2008) 40, (189-197)) Nature Genetics. 40: 1384. DOI: 10.1038/ng1108-1384a  0.32
2007 Clark TG, Andrew T, Cooper GM, Margulies EH, Mullikin JC, Balding DJ. Functional constraint and small insertions and deletions in the ENCODE regions of the human genome Genome Biology. 8. PMID 17784950 DOI: 10.1186/gb-2007-8-9-r180  0.32
2007 Kaelin CB, Cooper GM, Sidow A, Barsh GS. Mammalian comparative sequence analysis of the Agrp locus. Plos One. 2: e702. PMID 17684549 DOI: 10.1371/journal.pone.0000702  0.32
2007 Tullai JW, Schaffer ME, Mullenbrock S, Sholder G, Kasif S, Cooper GM. Immediate-early and delayed primary response genes are distinct in function and genomic architecture. The Journal of Biological Chemistry. 282: 23981-95. PMID 17575275 DOI: 10.1074/jbc.M702044200  0.8
2007 Margulies EH, Cooper GM, Asimenos G, Thomas DJ, Dewey CN, Siepel A, Birney E, Keefe D, Schwartz AS, Hou M, Taylor J, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, et al. Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Research. 17: 760-74. PMID 17567995 DOI: 10.1101/gr.6034307  0.32
2007 Tullai JW, Chen J, Schaffer ME, Kamenetsky E, Kasif S, Cooper GM. Glycogen synthase kinase-3 represses cyclic AMP response element-binding protein (CREB)-targeted immediate early genes in quiescent cells. The Journal of Biological Chemistry. 282: 9482-91. PMID 17277356 DOI: 10.1074/jbc.M700067200  0.8
2007 Adams KW, Cooper GM. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis. The Journal of Biological Chemistry. 282: 6192-200. PMID 17200126 DOI: 10.1074/jbc.M610643200  0.8
2005 Stone EA, Cooper GM, Sidow A. Trade-offs in detecting evolutionarily constrained sequence by comparative genomics. Annual Review of Genomics and Human Genetics. 6: 143-64. PMID 16124857 DOI: 10.1146/annurev.genom.6.080604.162146  0.32
2005 Cooper GM, Stone EA, Asimenos G, Green ED, Batzoglou S, Sidow A. Distribution and intensity of constraint in mammalian genomic sequence. Genome Research. 15: 901-13. PMID 15965027 DOI: 10.1101/gr.3577405  0.32
2005 Gross VS, Hess M, Cooper GM. Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis. Molecular Reproduction and Development. 70: 324-32. PMID 15625701 DOI: 10.1002/mrd.20212  0.8
2004 Cooper GM, Singaravelu SAG, Sidow A. ABC: Software for interactive browsing of genomic multiple sequence alignment data Bmc Bioinformatics. 5. PMID 15588288 DOI: 10.1186/1471-2105-5-192  0.32
2004 Martín J, Odoom K, Tuite G, Dunn G, Hopewell N, Cooper G, Fitzharris C, Butler K, Hall WW, Minor PD. Long-term excretion of vaccine-derived poliovirus by a healthy child Journal of Virology. 78: 13839-13847. PMID 15564492 DOI: 10.1128/JVI.78.24.13839-13847.2004  1
2004 Feingold EA, Good PJ, Guyer MS, Kamholz S, Liefer L, Wetterstrand K, Collins FS, Gingeras TR, Kampa D, Sekinger EA, Cheng J, Hirsch H, Ghosh S, Zhu Z, Patel S, ... ... Cooper GM, et al. The ENCODE (ENCyclopedia of DNA Elements) Project Science. 306: 636-640. PMID 15499007 DOI: 10.1126/science.1105136  0.32
2004 Tullai JW, Schaffer ME, Mullenbrock S, Kasif S, Cooper GM. Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways. The Journal of Biological Chemistry. 279: 20167-77. PMID 14769801 DOI: 10.1074/jbc.M309260200  0.8
2003 Pagon Z, Volker J, Cooper GM, Hansen U. Mammalian transcription factor LSF is a target of ERK signaling. Journal of Cellular Biochemistry. 89: 733-46. PMID 12858339 DOI: 10.1002/jcb.10549  0.8
2002 Martín J, Samoilovich E, Dunn G, Lackenby A, Feldman E, Heath A, Svirchevskaya E, Cooper G, Yermalovich M, Minor PD. Isolation of an intertypic poliovirus capsid recombinant from a child with vaccine-associated paralytic poliomyelitis Journal of Virology. 76: 10921-10928. PMID 12368335 DOI: 10.1128/JVI.76.21.10921-10928.2002  1
2002 Hartley D, Cooper GM. Role of mTOR in the degradation of IRS-1: regulation of PP2A activity. Journal of Cellular Biochemistry. 85: 304-14. PMID 11948686 DOI: 10.1002/jcb.10135  0.8
1996 Yao QY, Tierney RJ, Croom-Carter D, Cooper GM, Ellis CJ, Rowe M, Rickinson AB. Isolation of intertypic recombinants of Epstein-Barr virus from T- cell-immunocompromised individuals Journal of Virology. 70: 4895-4903. PMID 8763992  1
1996 Yao QY, Tierney RJ, Croom-Carter D, Dukers D, Cooper GM, Ellis CJ, Rowe M, Rickinson AB. Frequency of multiple Epstein-Barr virus infections in T-cell- immunocompromised individuals Journal of Virology. 70: 4884-4894. PMID 8763991  1
1984 Cooper GM. Structural and functional analysis of ras and Blym oncogenes Current Topics in Microbiology and Immunology. 113: 34-36. PMID 6478867  1
1976 Cooper GM, Temin HM. Lack of infectivity of the endogenous avian leukosis virus-related genes in the DNA of uninfected chicken cells. Journal of Virology. 17: 422-30. PMID 176424  1
1975 Cooper GM, Temin HM. Infectious DNA from cells infected with Rous sarcoma virus, reticuloendotheliosis virus or Rous-associated virus-O. Cold Spring Harbor Symposia On Quantitative Biology. 39: 1027-32. PMID 169004  1
1975 Schildkraut I, Cooper GM, Greer S. Selective inhibition of the replication of herpes simplex virus by 5-halogenated analogues of deoxycytidine. Molecular Pharmacology. 11: 153-8. PMID 164617  1
1974 Cooper GM, Temin HM. Infectious rous sarcoma virus and reticuloendotheliosis virus DNAs. Journal of Virology. 14: 1132-41. PMID 4372391  1
1973 Cooper GM, Greer S. Phosphorylation of 5-halogenated deoxycytidine analogues by deoxycytidine kinase. Molecular Pharmacology. 9: 704-10. PMID 4762632  1
1973 Cooper GM, Greer S. The effect of inhibition of cytidine deaminase by tetrahydrouridine on the utilization of deoxycytidine and 5-bromodeoxycytidine for deoxyribonucleic acid synthesis. Molecular Pharmacology. 9: 698-703. PMID 4762631  1
1973 Cooper GM. Phosphorylation of 5 bromodeoxycytidine in cells infected with herpes simplex virus Proceedings of the National Academy of Sciences of the United States of America. 70: II. PMID 4359489  1
1972 Cooper GM, Dunning WF, Greer S. Role of catabolism in pyrimidine utilization for nucleic acid synthesis in vivo. Cancer Research. 32: 390-7. PMID 5058194  1
1970 Cooper GM, Greer S. Irreversible inhibition of dehalogenation of 5-iodouracil by 5-diazouracil and reversible inhibition by 5-cyanouracil. Cancer Research. 30: 2937-41. PMID 5494578  1
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