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Balendu S. Avvaru, Ph.D. - Publications

Affiliations: 
2010 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Biochemistry, General Biophysics, Molecular Biology
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14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kim JK, Lomelino CL, Avvaru BS, Mahon BP, McKenna R, Park S, Kim CU. Active-site solvent replenishment observed during human carbonic anhydrase II catalysis. Iucrj. 5: 93-102. PMID 29354275 DOI: 10.2210/Pdb5Y2S/Pdb  0.687
2016 Kim CU, Song H, Avvaru BS, Gruner SM, Park S, McKenna R. Tracking solvent and protein movement during CO2 release in carbonic anhydrase II crystals. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114542 DOI: 10.1073/Pnas.1520786113  0.666
2013 Mikulski R, West D, Sippel KH, Avvaru BS, Aggarwal M, Tu C, McKenna R, Silverman DN. Water networks in fast proton transfer during catalysis by human carbonic anhydrase II. Biochemistry. 52: 125-31. PMID 23215152 DOI: 10.1021/Bi301099K  0.692
2011 Carta F, Garaj V, Maresca A, Wagner J, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT. Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry. 19: 3105-19. PMID 21515057 DOI: 10.1016/J.Bmc.2011.04.005  0.607
2011 Mikulski R, Avvaru BS, Tu C, Case N, McKenna R, Silverman DN. Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II. Archives of Biochemistry and Biophysics. 506: 181-7. PMID 21145876 DOI: 10.1016/J.Abb.2010.12.004  0.698
2010 Pacchiano F, Aggarwal M, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT. Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Chemical Communications (Cambridge, England). 46: 8371-3. PMID 20922253 DOI: 10.1039/C0Cc02707C  0.76
2010 Avvaru BS, Arenas DJ, Tu C, Tanner DB, McKenna R, Silverman DN. Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II. Archives of Biochemistry and Biophysics. 502: 53-9. PMID 20637176 DOI: 10.1016/J.Abb.2010.07.010  0.643
2010 Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 4376-81. PMID 20605094 DOI: 10.1016/J.Bmcl.2010.06.082  0.663
2010 Wagner J, Avvaru BS, Robbins AH, Scozzafava A, Supuran CT, McKenna R. Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations. Bioorganic & Medicinal Chemistry. 18: 4873-8. PMID 20598552 DOI: 10.1016/J.Bmc.2010.06.028  0.657
2010 Avvaru BS, Kim CU, Sippel KH, Gruner SM, Agbandje-McKenna M, Silverman DN, McKenna R. A short, strong hydrogen bond in the active site of human carbonic anhydrase II. Biochemistry. 49: 249-51. PMID 20000378 DOI: 10.1021/Bi902007B  0.749
2009 Avvaru BS, Busby SA, Chalmers MJ, Griffin PR, Venkatakrishnan B, Agbandje-McKenna M, Silverman DN, McKenna R. Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network. Biochemistry. 48: 7365-72. PMID 19583303 DOI: 10.1021/Bi9007512  0.695
2009 Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties. Biochemistry. 48: 1322-31. PMID 19170619 DOI: 10.1021/Bi802035F  0.71
2008 Zheng J, Avvaru BS, Tu C, McKenna R, Silverman DN. Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II. Biochemistry. 47: 12028-36. PMID 18942852 DOI: 10.1021/Bi801473W  0.693
2008 Domsic JF, Avvaru BS, Kim CU, Gruner SM, Agbandje-McKenna M, Silverman DN, McKenna R. Entrapment of carbon dioxide in the active site of carbonic anhydrase II. The Journal of Biological Chemistry. 283: 30766-71. PMID 18768466 DOI: 10.1074/Jbc.M805353200  0.736
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