Susan Gasser, Ph.D. - Publications

1986-2001 Swiss Institute for Experimental Cancer Research, Lausanne, VD, Switzerland 
 2001-2004 Molecular Biology Université de Genève, Genève, Genève, Switzerland 
 2004- Friedrich Miescher Institute for Biomedical Research, Basel, Basel-Stadt, Switzerland 
 2005- Molecular Biology Universität Basel, Basel, Basel-Stadt, Switzerland 

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gübeli RJ, Bertoldo D, Shimada K, Gerhold CB, Hurst V, Takahashi Y, Harada K, Mothukuri GK, Wilbs J, Harata M, Gasser SM, Heinis C. -Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4. Acs Chemical Biology. PMID 33843189 DOI: 10.1021/acschembio.0c00825  0.36
2021 Fuchs J, Cheblal A, Gasser SM. Underappreciated Roles of DNA Polymerase δ in Replication Stress Survival. Trends in Genetics : Tig. PMID 33608117 DOI: 10.1016/j.tig.2020.12.003  0.36
2021 Challa K, Schmid CD, Kitagawa S, Cheblal A, Iesmantavicius V, Seeber A, Amitai A, Seebacher J, Hauer MH, Shimada K, Gasser SM. Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair. Molecular Cell. PMID 33529595 DOI: 10.1016/j.molcel.2020.12.021  0.6
2020 Padeken J, Methot S, Zeller P, Delaney CE, Kalck V, Gasser SM. Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression. Genes & Development. PMID 33303642 DOI: 10.1101/gad.344234.120  0.32
2020 Forey R, Barthe A, Tittel-Elmer M, Wery M, Barrault MB, Ducrot C, Seeber A, Krietenstein N, Szachnowski U, Skrzypczak M, Ginalski K, Rowicka M, Cobb JA, Rando OJ, Soutourina J, ... ... Gasser SM, et al. A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization. Molecular Cell. PMID 33278361 DOI: 10.1016/j.molcel.2020.11.010  0.6
2020 Cheblal A, Challa K, Seeber A, Shimada K, Yoshida H, Ferreira HC, Amitai A, Gasser SM. DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement. Molecular Cell. PMID 32970994 DOI: 10.1016/j.molcel.2020.09.002  0.6
2020 Mattout A, Gaidatzis D, Kalck V, Gasser SM. A Nuclear RNA Degradation Pathway Helps Silence Polycomb/H3K27me3-Marked Loci in . Cold Spring Harbor Symposia On Quantitative Biology. PMID 32350050 DOI: 10.1101/sqb.2019.84.040238  1
2020 Mattout A, Gaidatzis D, Padeken J, Schmid CD, Aeschimann F, Kalck V, Gasser SM. LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay. Nature Cell Biology. PMID 32251399 DOI: 10.1038/s41556-020-0504-1  1
2020 Harr JC, Schmid CD, Muñoz-Jiménez C, Romero-Bueno R, Kalck V, Gonzalez-Sandoval A, Hauer MH, Padeken J, Askjaer P, Mattout A, Gasser SM. Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model. Genes & Development. PMID 32139421 DOI: 10.1101/gad.332213.119  1
2020 Deshpande I, Keusch JJ, Challa K, Iesmantavicius V, Gasser SM, Gut H. The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin. The Embo Journal. 39: e103976. PMID 31894584 DOI: 10.15252/embj.2019103976  0.32
2019 Deshpande I, Keusch JJ, Challa K, Iesmantavicius V, Gasser SM, Gut H. The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin. The Embo Journal. e101744. PMID 31515872 DOI: 10.15252/embj.2019101744  0.32
2019 Cabianca DS, Muñoz-Jiménez C, Kalck V, Gaidatzis D, Padeken J, Seeber A, Askjaer P, Gasser SM. Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei. Nature. 569: 734-739. PMID 31118512 DOI: 10.1038/S41586-019-1243-Y  1
2019 Hurst V, Shimada K, Gasser SM. Nuclear Actin and Actin-Binding Proteins in DNA Repair. Trends in Cell Biology. PMID 30954333 DOI: 10.1016/j.tcb.2019.02.010  0.36
2019 Padeken J, Zeller P, Towbin B, Katic I, Kalck V, Methot SP, Gasser SM. Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression. Genes & Development. PMID 30804228 DOI: 10.1101/gad.322495.118  0.32
2019 Delaney CE, Methot SP, Guidi M, Katic I, Gasser SM, Padeken J. Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65. The Journal of Cell Biology. PMID 30737265 DOI: 10.1083/jcb.201811038  0.32
2019 Klein HL, Bačinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, ... ... Gasser SM, et al. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell (Graz, Austria). 6: 1-64. PMID 30652105 DOI: 10.15698/Mic2019.01.664  0.36
2018 Seeber A, Hauer MH, Gasser SM. Chromosome Dynamics in Response to DNA Damage. Annual Review of Genetics. PMID 30208290 DOI: 10.1146/Annurev-Genet-120417-031334  0.6
2018 Marcomini I, Shimada K, Delgoshaie N, Yamamoto I, Seeber A, Cheblal A, Horigome C, Naumann U, Gasser SM. Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation. Cell Reports. 24: 2614-2628.e4. PMID 30184497 DOI: 10.1016/J.Celrep.2018.07.102  0.6
2017 Hauer MH, Gasser SM. Chromatin and nucleosome dynamics in DNA damage and repair. Genes & Development. 31: 2204-2221. PMID 29284710 DOI: 10.1101/gad.307702.117  0.6
2017 Deshpande I, Seeber A, Shimada K, Keusch JJ, Gut H, Gasser SM. Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Molecular Cell. PMID 29033322 DOI: 10.1016/J.Molcel.2017.09.019  0.6
2017 Shimada K, Gasser SM. A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage. The Journal of Cell Biology. PMID 28235945 DOI: 10.1083/jcb.201701038  0.36
2017 Amitai A, Seeber A, Gasser SM, Holcman D. Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories. Cell Reports. 18: 1200-1214. PMID 28147275 DOI: 10.1016/J.Celrep.2017.01.018  0.6
2017 Hauer MH, Seeber A, Singh V, Thierry R, Sack R, Amitai A, Kryzhanovska M, Eglinger J, Holcman D, Owen-Hughes T, Gasser SM. Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates. Nature Structural & Molecular Biology. PMID 28067915 DOI: 10.1038/Nsmb.3347  0.6
2016 Seeber A, Hegnauer AM, Hustedt N, Deshpande I, Poli J, Eglinger J, Pasero P, Gut H, Shinohara M, Hopfner KP, Shimada K, Gasser SM. RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. Molecular Cell. PMID 27889450 DOI: 10.1016/J.Molcel.2016.10.032  0.6
2016 Seeber A, Gasser SM. Chromatin organization and dynamics in double-strand break repair. Current Opinion in Genetics & Development. 43: 9-16. PMID 27810555 DOI: 10.1016/J.Gde.2016.10.005  0.88
2016 Gonzalez-Sandoval A, Gasser SM. Mechanism of chromatin segregation to the nuclear periphery in C. elegans embryos. Worm. 5: e1190900. PMID 27695653 DOI: 10.1080/21624054.2016.1190900  1
2016 Zeller P, Padeken J, van Schendel R, Kalck V, Tijsterman M, Gasser SM. Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability. Nature Genetics. 48: 1385-1395. PMID 27668659 DOI: 10.1038/ng.3672  0.32
2016 Horigome C, Gasser SM. SUMO wrestles breaks to the nuclear ring's edge. Cell Cycle (Georgetown, Tex.). 15: 3011-3013. PMID 27484885 DOI: 10.1080/15384101.2016.1216904  0.36
2016 Gonzalez-Sandoval A, Gasser SM. On TADs and LADs: Spatial Control Over Gene Expression. Trends in Genetics : Tig. PMID 27312344 DOI: 10.1016/j.tig.2016.05.004  1
2016 Cabianca DS, Gasser SM. Spatial segregation of heterochromatin: Uncovering functionality in a multicellular organism. Nucleus (Austin, Tex.). 7: 301-7. PMID 27187571 DOI: 10.1080/19491034.2016.1187354  0.32
2016 Horigome C, Bustard DE, Marcomini I, Delgoshaie N, Tsai-Pflugfelder M, Cobb JA, Gasser SM. PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL. Genes & Development. PMID 27056668 DOI: 10.1101/gad.277665.116  1
2016 Poli J, Gerhold CB, Tosi A, Hustedt N, Seeber A, Sack R, Herzog F, Pasero P, Shimada K, Hopfner KP, Gasser SM. Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress. Genes & Development. 30: 337-54. PMID 26798134 DOI: 10.1101/Gad.273813.115  0.6
2016 Harr JC, Gonzalez-Sandoval A, Gasser SM. Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man. Embo Reports. 17: 139-55. PMID 26792937 DOI: 10.15252/embr.201541809  1
2015 Gonzalez-Sandoval A, Towbin BD, Kalck V, Cabianca DS, Gaidatzis D, Hauer MH, Geng L, Wang L, Yang T, Wang X, Zhao K, Gasser SM. Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos. Cell. PMID 26607792 DOI: 10.1016/j.cell.2015.10.066  1
2015 Mattout A, Aaronson Y, Sailaja BS, Raghu Ram EV, Harikumar A, Mallm JP, Sim KH, Nissim-Rafinia M, Supper E, Singh PB, Sze SK, Gasser SM, Rippe K, Meshorer E. Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells. Genome Biology. 16: 213. PMID 26415775 DOI: 10.1186/s13059-015-0760-8  1
2015 Mattout A, Cabianca DS, Gasser SM. Chromatin states and nuclear organization in development--a view from the nuclear lamina. Genome Biology. 16: 174. PMID 26303512 DOI: 10.1186/s13059-015-0747-5  1
2015 Marcomini I, Gasser SM. Nuclear organization in DNA end processing: Telomeres vs double-strand breaks. Dna Repair. 32: 134-40. PMID 26004856 DOI: 10.1016/j.dnarep.2015.04.024  0.36
2015 Padeken J, Zeller P, Gasser SM. Repeat DNA in genome organization and stability. Current Opinion in Genetics & Development. 31: 12-9. PMID 25917896 DOI: 10.1016/j.gde.2015.03.009  0.32
2015 Horigome C, Dion V, Seeber A, Gehlen LR, Gasser SM. Visualizing the spatiotemporal dynamics of DNA damage in budding yeast. Methods in Molecular Biology (Clifton, N.J.). 1292: 77-96. PMID 25804749 DOI: 10.1007/978-1-4939-2522-3_6  0.6
2015 Hustedt N, Seeber A, Sack R, Tsai-Pflugfelder M, Bhullar B, Vlaming H, van Leeuwen F, Guénolé A, van Attikum H, Srivas R, Ideker T, Shimada K, Gasser SM. Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling. Molecular Cell. 57: 273-89. PMID 25533186 DOI: 10.1016/J.Molcel.2014.11.016  1
2015 Gerhold CB, Hauer MH, Gasser SM. INO80-C and SWR-C: guardians of the genome. Journal of Molecular Biology. 427: 637-51. PMID 25451604 DOI: 10.1016/j.jmb.2014.10.015  0.6
2014 Horigome C, Oma Y, Konishi T, Schmid R, Marcomini I, Hauer MH, Dion V, Harata M, Gasser SM. SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice. Molecular Cell. 55: 626-39. PMID 25066231 DOI: 10.1016/j.molcel.2014.06.027  1
2014 Weisman R, Cohen A, Gasser SM. TORC2-a new player in genome stability. Embo Molecular Medicine. 6: 995-1002. PMID 24992933 DOI: 10.15252/Emmm.201403959  1
2014 Seeber A, Dion V, Gasser SM. Remodelers move chromatin in response to DNA damage. Cell Cycle (Georgetown, Tex.). 13: 877-8. PMID 24552812 DOI: 10.4161/Cc.28200  0.6
2013 Hustedt N, Gasser SM, Shimada K. Replication checkpoint: tuning and coordination of replication forks in s phase. Genes. 4: 388-434. PMID 24705211 DOI: 10.3390/genes4030388  0.36
2013 Ferreira HC, Towbin BD, Jegou T, Gasser SM. The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery. The Journal of Cell Biology. 203: 727-35. PMID 24297748 DOI: 10.1083/jcb.201307181  1
2013 Gasser SM, le Coutre J. Nutrition and the biology of human ageing: molecular mechanisms underlying ageing. The Journal of Nutrition, Health & Aging. 17: 710-1. PMID 24097028 DOI: 10.1007/s12603-013-0373-4  1
2013 Shimada K, Filipuzzi I, Stahl M, Helliwell SB, Studer C, Hoepfner D, Seeber A, Loewith R, Movva NR, Gasser SM. TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Molecular Cell. 51: 829-39. PMID 24035500 DOI: 10.1016/J.Molcel.2013.08.019  1
2013 Seeber A, Dion V, Gasser SM. Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes & Development. 27: 1999-2008. PMID 24029917 DOI: 10.1101/Gad.222992.113  0.6
2013 Dion V, Kalck V, Seeber A, Schleker T, Gasser SM. Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. Embo Reports. 14: 984-91. PMID 24018421 DOI: 10.1038/Embor.2013.142  0.6
2013 Grunstein M, Gasser SM. Epigenetics in Saccharomyces cerevisiae. Cold Spring Harbor Perspectives in Biology. 5. PMID 23818500 DOI: 10.1101/cshperspect.a017491  1
2013 Towbin BD, Gonzalez-Sandoval A, Gasser SM. Mechanisms of heterochromatin subnuclear localization. Trends in Biochemical Sciences. 38: 356-63. PMID 23746617 DOI: 10.1016/j.tibs.2013.04.004  1
2013 Gonzalez-Sandoval A, Towbin BD, Gasser SM. The formation and sequestration of heterochromatin during development: delivered on 7 September 2012 at the 37th FEBS Congress in Sevilla, Spain. The Febs Journal. 280: 3212-9. PMID 23648132 DOI: 10.1111/febs.12319  1
2013 Rohner S, Kalck V, Wang X, Ikegami K, Lieb JD, Gasser SM, Meister P. Promoter- and RNA polymerase II-dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans. The Journal of Cell Biology. 200: 589-604. PMID 23460676 DOI: 10.1083/jcb.201207024  1
2013 Seeber A, Hauer M, Gasser SM. Nucleosome remodelers in double-strand break repair. Current Opinion in Genetics & Development. 23: 174-84. PMID 23352131 DOI: 10.1016/J.Gde.2012.12.008  0.6
2013 Oppikofer M, Kueng S, Keusch JJ, Hassler M, Ladurner AG, Gut H, Gasser SM. Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. The Embo Journal. 32: 437-49. PMID 23299941 DOI: 10.1038/Emboj.2012.343  0.32
2012 Towbin BD, González-Aguilera C, Sack R, Gaidatzis D, Kalck V, Meister P, Askjaer P, Gasser SM. Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. Cell. 150: 934-47. PMID 22939621 DOI: 10.1016/j.cell.2012.06.051  1
2012 Hegnauer AM, Hustedt N, Shimada K, Pike BL, Vogel M, Amsler P, Rubin SM, van Leeuwen F, Guénolé A, van Attikum H, Thomä NH, Gasser SM. An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks. The Embo Journal. 31: 3768-83. PMID 22820947 DOI: 10.1038/emboj.2012.195  1
2012 Shimada K, Gasser SM. DNA replication: Pif1 pulls the plug on stalled replication forks. Current Biology : Cb. 22: R404-5. PMID 22625857 DOI: 10.1016/j.cub.2012.04.015  0.36
2012 Dion V, Kalck V, Horigome C, Towbin BD, Gasser SM. Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nature Cell Biology. 14: 502-9. PMID 22484486 DOI: 10.1038/ncb2465  1
2011 Meister P, Schott S, Bedet C, Xiao Y, Rohner S, Bodennec S, Hudry B, Molin L, Solari F, Gasser SM, Palladino F. Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism. Genome Biology. 12: R123. PMID 22185090 DOI: 10.1186/gb-2011-12-12-r123  1
2011 Mattout A, Pike BL, Towbin BD, Bank EM, Gonzalez-Sandoval A, Stadler MB, Meister P, Gruenbaum Y, Gasser SM. An EDMD mutation in C. elegans lamin blocks muscle-specific gene relocation and compromises muscle integrity. Current Biology : Cb. 21: 1603-14. PMID 21962710 DOI: 10.1016/J.Cub.2011.08.030  1
2011 Ehrentraut S, Hassler M, Oppikofer M, Kueng S, Weber JM, Mueller JW, Gasser SM, Ladurner AG, Ehrenhofer-Murray AE. Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79. Genes & Development. 25: 1835-46. PMID 21896656 DOI: 10.1101/Gad.17175111  1
2011 Horigome C, Okada T, Shimazu K, Gasser SM, Mizuta K. Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres. The Embo Journal. 30: 3799-811. PMID 21822217 DOI: 10.1038/emboj.2011.267  1
2011 Ferreira HC, Luke B, Schober H, Kalck V, Lingner J, Gasser SM. The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nature Cell Biology. 13: 867-74. PMID 21666682 DOI: 10.1038/Ncb2263  1
2011 Oppikofer M, Kueng S, Martino F, Soeroes S, Hancock SM, Chin JW, Fischle W, Gasser SM. A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. The Embo Journal. 30: 2610-21. PMID 21666601 DOI: 10.1038/Emboj.2011.170  1
2011 Meister P, Mango SE, Gasser SM. Locking the genome: nuclear organization and cell fate. Current Opinion in Genetics & Development. 21: 167-74. PMID 21345665 DOI: 10.1016/j.gde.2011.01.023  1
2011 Stulemeijer IJ, Pike BL, Faber AW, Verzijlbergen KF, van Welsem T, Frederiks F, Lenstra TL, Holstege FC, Gasser SM, van Leeuwen F. Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms. Epigenetics & Chromatin. 4: 2. PMID 21291527 DOI: 10.1186/1756-8935-4-2  1
2011 Kitada T, Schleker T, Sperling AS, Xie W, Gasser SM, Grunstein M. γH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle (Georgetown, Tex.). 10: 293-300. PMID 21212735 DOI: 10.4161/Cc.10.2.14536  1
2011 Gehlen LR, Nagai S, Shimada K, Meister P, Taddei A, Gasser SM. Nuclear geometry and rapid mitosis ensure asymmetric episome segregation in yeast. Current Biology : Cb. 21: 25-33. PMID 21194950 DOI: 10.1016/j.cub.2010.12.016  1
2011 Gasser SM, Li E. Epigenetics and disease: pharmaceutical opportunities. Preface Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 67. PMID 21141721  1
2010 Towbin BD, Meister P, Pike BL, Gasser SM. Repetitive transgenes in C. elegans accumulate heterochromatic marks and are sequestered at the nuclear envelope in a copy-number- and lamin-dependent manner. Cold Spring Harbor Symposia On Quantitative Biology. 75: 555-65. PMID 21467137 DOI: 10.1101/sqb.2010.75.041  1
2010 Meister P, Gehlen LR, Varela E, Kalck V, Gasser SM. Visualizing yeast chromosomes and nuclear architecture. Methods in Enzymology. 470: 535-67. PMID 20946824 DOI: 10.1016/S0076-6879(10)70021-5  1
2010 Taddei A, Schober H, Gasser SM. The budding yeast nucleus. Cold Spring Harbor Perspectives in Biology. 2: a000612. PMID 20554704 DOI: 10.1101/cshperspect.a000612  1
2010 Yoshida T, Shimada K, Oma Y, Kalck V, Akimura K, Taddei A, Iwahashi H, Kugou K, Ohta K, Gasser SM, Harata M. Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores. Plos Genetics. 6: e1000910. PMID 20419146 DOI: 10.1371/journal.pgen.1000910  0.36
2010 Varela E, Schlecht U, Moina A, Fackenthal JD, Washburn BK, Niederhauser-Wiederkehr C, Tsai-Pflugfelder M, Primig M, Gasser SM, Esposito RE. Mitotic expression of Spo13 alters M-phase progression and nucleolar localization of Cdc14 in budding yeast. Genetics. 185: 841-54. PMID 20407133 DOI: 10.1534/Genetics.109.113746  1
2010 Meister P, Towbin BD, Pike BL, Ponti A, Gasser SM. The spatial dynamics of tissue-specific promoters during C. elegans development. Genes & Development. 24: 766-82. PMID 20395364 DOI: 10.1101/gad.559610  1
2010 Dion V, Shimada K, Gasser SM. Actin-related proteins in the nucleus: life beyond chromatin remodelers. Current Opinion in Cell Biology. 22: 383-91. PMID 20303249 DOI: 10.1016/  0.36
2010 Ebrahimi H, Robertson ED, Taddei A, Gasser SM, Donaldson AD, Hiraga S. Early initiation of a replication origin tethered at the nuclear periphery. Journal of Cell Science. 123: 1015-9. PMID 20197407 DOI: 10.1242/jcs.060392  1
2010 Schleker T, Shimada K, Sack R, Pike BL, Gasser SM. Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation. Cell Cycle (Georgetown, Tex.). 9: 350-63. PMID 20046099 DOI: 10.4161/cc.9.2.10448  1
2009 Bühler M, Gasser SM. Silent chromatin at the middle and ends: lessons from yeasts. The Embo Journal. 28: 2149-61. PMID 19629038 DOI: 10.1038/emboj.2009.185  1
2009 Schober H, Ferreira H, Kalck V, Gehlen LR, Gasser SM. Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes & Development. 23: 928-38. PMID 19390087 DOI: 10.1101/gad.1787509  1
2009 Varela E, Shimada K, Laroche T, Leroy D, Gasser SM. Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression. The Embo Journal. 28: 1562-75. PMID 19387493 DOI: 10.1038/emboj.2009.111  1
2009 Towbin BD, Meister P, Gasser SM. The nuclear envelope--a scaffold for silencing? Current Opinion in Genetics & Development. 19: 180-6. PMID 19303765 DOI: 10.1016/j.gde.2009.01.006  1
2009 Friedel AM, Pike BL, Gasser SM. ATR/Mec1: coordinating fork stability and repair. Current Opinion in Cell Biology. 21: 237-44. PMID 19230642 DOI: 10.1016/  1
2009 Martino F, Kueng S, Robinson P, Tsai-Pflugfelder M, van Leeuwen F, Ziegler M, Cubizolles F, Cockell MM, Rhodes D, Gasser SM. Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Molecular Cell. 33: 323-34. PMID 19217406 DOI: 10.1016/J.Molcel.2009.01.009  1
2008 Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (New York, N.Y.). 322: 597-602. PMID 18948542 DOI: 10.1126/Science.1162790  1
2008 Shimada K, Oma Y, Schleker T, Kugou K, Ohta K, Harata M, Gasser SM. Ino80 chromatin remodeling complex promotes recovery of stalled replication forks. Current Biology : Cb. 18: 566-75. PMID 18406137 DOI: 10.1016/j.cub.2008.03.049  0.36
2008 Rohner S, Gasser SM, Meister P. Modules for cloning-free chromatin tagging in Saccharomyces cerevisae. Yeast (Chichester, England). 25: 235-9. PMID 18302313 DOI: 10.1002/yea.1580  1
2008 Schober H, Kalck V, Vega-Palas MA, Van Houwe G, Sage D, Unser M, Gartenberg MR, Gasser SM. Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast. Genome Research. 18: 261-71. PMID 18096749 DOI: 10.1101/Gr.6687808  1
2007 Sexton T, Schober H, Fraser P, Gasser SM. Gene regulation through nuclear organization. Nature Structural & Molecular Biology. 14: 1049-55. PMID 17984967 DOI: 10.1038/nsmb1324  1
2007 Meister P, Taddei A, Ponti A, Baldacci G, Gasser SM. Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. The Embo Journal. 26: 1315-26. PMID 17304223 DOI: 10.1038/sj.emboj.7601538  1
2007 Shimada K, Gasser SM. The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae. Cell. 128: 85-99. PMID 17218257 DOI: 10.1016/j.cell.2006.11.045  0.36
2006 Meister P, Taddei A, Gasser SM. In and out of the replication factory. Cell. 125: 1233-5. PMID 16814710 DOI: 10.1016/j.cell.2006.06.014  1
2006 Taddei A, Van Houwe G, Hediger F, Kalck V, Cubizolles F, Schober H, Gasser SM. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature. 441: 774-8. PMID 16760983 DOI: 10.1038/nature04845  1
2006 Hediger F, Berthiau AS, van Houwe G, Gilson E, Gasser SM. Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. The Embo Journal. 25: 857-67. PMID 16467853 DOI: 10.1038/sj.emboj.7600976  1
2006 Rosa A, Maddocks JH, Neumann FR, Gasser SM, Stasiak A. Measuring limits of telomere movement on nuclear envelope. Biophysical Journal. 90: L24-6. PMID 16339888 DOI: 10.1529/biophysj.105.077974  1
2006 Gehlen LR, Rosa A, Klenin K, Langowski J, Gasser SM, Bystricky K. Spatially confined polymer chains: Implications of chromatin fibre flexibility and peripheral anchoring on telomere-telomere interaction Journal of Physics Condensed Matter. 18: S245-S252. DOI: 10.1088/0953-8984/18/14/S09  1
2006 Rosa A, Neumann FR, Gasser SM, Stasiak A. Long time behaviour of diffusing particles in constrained geometries; Application to chromatin motion Journal of Physics Condensed Matter. 18: S235-S243. DOI: 10.1088/0953-8984/18/14/S08  1
2005 Cobb JA, Schleker T, Rojas V, Bjergbaek L, Tercero JA, Gasser SM. Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes & Development. 19: 3055-69. PMID 16357221 DOI: 10.1101/gad.361805  1
2005 Bystricky K, Laroche T, van Houwe G, Blaszczyk M, Gasser SM. Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization. The Journal of Cell Biology. 168: 375-87. PMID 15684028 DOI: 10.1083/jcb.200409091  1
2005 Bjergbaek L, Cobb JA, Tsai-Pflugfelder M, Gasser SM. Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. The Embo Journal. 24: 405-17. PMID 15616582 DOI: 10.1038/sj.emboj.7600511  1
2004 Gartenberg MR, Neumann FR, Laroche T, Blaszczyk M, Gasser SM. Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell. 119: 955-67. PMID 15620354 DOI: 10.1016/J.Cell.2004.11.008  1
2004 Bystricky K, Heun P, Gehlen L, Langowski J, Gasser SM. Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques Proceedings of the National Academy of Sciences of the United States of America. 101: 16495-16500. PMID 15545610 DOI: 10.1073/pnas.0402766101  1
2004 Cobb JA, Shimada K, Gasser SM. Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response. Current Opinion in Genetics & Development. 14: 292-300. PMID 15172673 DOI: 10.1016/j.gde.2004.04.001  1
2003 Khakhar RR, Cobb JA, Bjergbaek L, Hickson ID, Gasser SM. RecQ helicases: multiple roles in genome maintenance. Trends in Cell Biology. 13: 493-501. PMID 12946629 DOI: 10.1016/S0962-8924(03)00171-5  1
2003 Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM. DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. The Embo Journal. 22: 4325-36. PMID 12912929 DOI: 10.1093/emboj/cdg391  1
2003 Spector DL, Gasser SM. A molecular dissection of nuclear function. Conference on the dynamic nucleus: questions and implications. Embo Reports. 4: 18-23. PMID 12524514 DOI: 10.1038/Sj.Embor.Embor701  1
2002 Shimada K, Pasero P, Gasser SM. ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes & Development. 16: 3236-52. PMID 12502744 DOI: 10.1101/gad.239802  0.36
2002 Bjergbaek L, Cobb JA, Gasser SM. RecQ helicases and genome stability: lessons from model organisms and human disease. Swiss Medical Weekly. 132: 433-42. PMID 12457301  1
2002 Duncker BP, Shimada K, Tsai-Pflugfelder M, Pasero P, Gasser SM. An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proceedings of the National Academy of Sciences of the United States of America. 99: 16087-92. PMID 12441400 DOI: 10.1073/pnas.252093999  0.36
2002 Cobb JA, Bjergbaek L, Gasser SM. RecQ helicases: at the heart of genetic stability. Febs Letters. 529: 43-8. PMID 12354611 DOI: 10.1016/S0014-5793(02)03269-6  1
2002 Teixeira MT, Forstemann K, Gasser SM, Lingner J. Intracellular trafficking of yeast telomerase components. Embo Reports. 3: 652-9. PMID 12101098 DOI: 10.1093/Embo-Reports/Kvf133  1
2002 Lamond AI, Gasser SM. Nucleus and gene expression Current Opinion in Cell Biology. 14: 259-261. DOI: 10.1016/S0955-0674(02)00323-X  1
2001 Heun P, Laroche T, Shimada K, Furrer P, Gasser SM. Chromosome dynamics in the yeast interphase nucleus. Science (New York, N.Y.). 294: 2181-6. PMID 11739961 DOI: 10.1126/science.1065366  1
2001 Heun P, Laroche T, Raghuraman MK, Gasser SM. The positioning and dynamics of origins of replication in the budding yeast nucleus. The Journal of Cell Biology. 152: 385-400. PMID 11266454 DOI: 10.1083/jcb.152.2.385  1
2001 Maillet L, Gaden F, Brevet V, Fourel G, Martin SG, Dubrana K, Gasser SM, Gilson E. Ku-deficient yeast strains exhibit alternative states of silencing competence. Embo Reports. 2: 203-10. PMID 11266361 DOI: 10.1093/Embo-Reports/Kve044  1
2001 Perrod S, Cockell MM, Laroche T, Renauld H, Ducrest AL, Bonnard C, Gasser SM. A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. The Embo Journal. 20: 197-209. PMID 11226170 DOI: 10.1093/emboj/20.1.197  1
2000 Laroche T, Martin SG, Tsai-Pflugfelder M, Gasser SM. The dynamics of yeast telomeres and silencing proteins through the cell cycle. Journal of Structural Biology. 129: 159-74. PMID 10806066 DOI: 10.1006/Jsbi.2000.4240  1
2000 Stone EM, Heun P, Laroche T, Pillus L, Gasser SM. MAP kinase signaling induces nuclear reorganization in budding yeast. Current Biology : Cb. 10: 373-82. PMID 10753745 DOI: 10.1016/S0960-9822(00)00413-9  1
1999 Blasco MA, Gasser SM, Lingner J. Telomeres and telomerase. Genes & Development. 13: 2353-9. PMID 10500091 DOI: 10.1101/Gad.13.18.2353  1
1999 Martin SG, Laroche T, Suka N, Grunstein M, Gasser SM. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell. 97: 621-33. PMID 10367891 DOI: 10.1016/S0092-8674(00)80773-4  1
1998 Cockell M, Gotta M, Palladino F, Martin SG, Gasser SM. Targeting Sir proteins to sites of action: a general mechanism for regulated repression. Cold Spring Harbor Symposia On Quantitative Biology. 63: 401-12. PMID 10384305 DOI: 10.1101/Sqb.1998.63.401  1
1998 Gotta M, Palladino F, Gasser SM. Functional characterization of the N terminus of Sir3p Molecular and Cellular Biology. 18: 6110-6120. PMID 9742128  1
1998 Laroche T, Martin SG, Gotta M, Gorham HC, Pryde FE, Louis EJ, Gasser SM. Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Current Biology : Cb. 8: 653-6. PMID 9635192 DOI: 10.1016/S0960-9822(98)70252-0  1
1998 Gasser SM, Paro R, Stewart F, Aasland R. The genetics of epigenetics. Cellular and Molecular Life Sciences : Cmls. 54: 1-5. PMID 9487382  1
1998 Gasser SM, Paro R, Stewart F, Aasland R. Epigenetic control of transcription. Introduction: The genetics of epigenetics Cellular and Molecular Life Sciences. 54: 1-5. DOI: 10.1007/s000180050120  1
1997 Gotta M, Strahl-Bolsinger S, Renauld H, Laroche T, Kennedy BK, Grunstein M, Gasser SM. Localization of Sir2p: the nucleolus as a compartment for silent information regulators. The Embo Journal. 16: 3243-55. PMID 9214640 DOI: 10.1093/Emboj/16.11.3243  1
1997 Kennedy BK, Gotta M, Sinclair DA, Mills K, McNabb DS, Murthy M, Pak SM, Laroche T, Gasser SM, Guarente L. Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell. 89: 381-91. PMID 9150138 DOI: 10.1016/S0092-8674(00)80219-6  1
1995 Grunstein M, Hecht A, Fisher-Adams G, Wan J, Mann RK, Strahl-Bolsinger S, Laroche T, Gasser S. The regulation of euchromatin and heterochromatin by histones in yeast. Journal of Cell Science. Supplement. 19: 29-36. PMID 8655644 DOI: 10.1242/Jcs.1995.Supplement_19.4  1
1995 Hecht A, Laroche T, Strahl-Bolsinger S, Gasser SM, Grunstein M. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell. 80: 583-92. PMID 7867066 DOI: 10.1016/0092-8674(95)90512-X  1
1995 Cockell M, Palladino F, Laroche T, Kyrion G, Liu C, Lustig AJ, Gasser SM. The carboxy termini of Sir4 and RAP1 affect Sir3 localization: Evidence for a multicomponent complex required for yeast telomeric silencing Journal of Cell Biology. 129: 909-924. PMID 7744964 DOI: 10.1083/jcb.129.4.909  1
1994 Dang Q, Alghisi GC, Gasser SM. Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction Journal of Molecular Biology. 243: 10-24. PMID 7932731 DOI: 10.1006/jmbi.1994.1626  1
1994 Palladino F, Gasser SM. Telomere maintenance and gene repression: a common end? Current Opinion in Cell Biology. 6: 373-379. PMID 7917328 DOI: 10.1016/0955-0674(94)90029-9  1
1993 Gilson E, Roberge M, Giraldo R, Rhodes D, Gasser SM. Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. Journal of Molecular Biology. 231: 293-310. PMID 8510148 DOI: 10.1006/Jmbi.1993.1283  1
1993 Palladino F, Laroche T, Gilson E, Axelrod A, Pillus L, Gasser SM. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres Cell. 75: 543-555. PMID 8221893 DOI: 10.1016/0092-8674(93)90388-7  1
1993 Palladino F, Laroche T, Gilson E, Pillus L, Gasser SM. The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane Cold Spring Harbor Symposia On Quantitative Biology. 58: 733-746. PMID 7956091 DOI: 10.1101/Sqb.1993.058.01.081  1
1992 Roberge M, Gasser SM. DNA loops: structural and functional properties of scaffold-attached regions. Molecular Microbiology. 6: 419-23. PMID 1560771 DOI: 10.1111/j.1365-2958.1992.tb01485.x  1
1992 Gasser SM, Walter R, Dang Q, Cardenas ME. Topoisomerase II: its functions and phosphorylation Antonie Van Leeuwenhoek. 62: 15-24. PMID 1332607 DOI: 10.1007/BF00584459  1
1992 Cardenas ME, Dang Q, Glover CV, Gasser SM. Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo. The Embo Journal. 11: 1785-96. PMID 1316274  1
1992 Klein F, Laroche T, Cardenas ME, Hofmann JF, Schweizer D, Gasser SM. Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast. The Journal of Cell Biology. 117: 935-48. PMID 1315786 DOI: 10.1083/jcb.117.5.935  1
1991 Raska I, Michel LS, Jarnik M, Dundr M, Fakan S, Gasser S, Gassmann M, Hubscher U, Izaurralde E, Martinez E, Richter A, Dubochet J. Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells Journal of Electron Microscopy Technique. 18: 91-105. PMID 1886006 DOI: 10.1002/Jemt.1060180202  1
1990 Cardenas ME, Laroche T, Gasser SM. The composition and morphology of yeast nuclear scaffolds. Journal of Cell Science. 96: 439-50. PMID 22096810  1
1990 Verdier JM, Stalder R, Roberge M, Amati B, Sentenac A, Gasser SM. Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro. Nucleic Acids Research. 18: 7033-9. PMID 2263463 DOI: 10.1093/Nar/18.23.7033  1
1990 Amati B, Pick L, Laroche T, Gasser SM. Nuclear scaffold attachment stimulates, but is not essential for ARS activity in Saccharomyces cerevisiae: analysis of the Drosophila ftz SAR. The Embo Journal. 9: 4007-16. PMID 2123454 DOI: 10.1002/J.1460-2075.1990.Tb07622.X  1
1990 Amati B, Gasser SM. Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts. Molecular and Cellular Biology. 10: 5442-54. PMID 2118998 DOI: 10.1128/mcb.10.10.5442  1
1989 Hofmann JF, Laroche T, Brand AH, Gasser SM. RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML. Cell. 57: 725-37. PMID 2655930 DOI: 10.1016/0092-8674(89)90788-5  1
1988 Mirkovitch J, Gasser SM, Laemmli UK. Scaffold attachment of DNA loops in metaphase chromosomes. Journal of Molecular Biology. 200: 101-9. PMID 3132557 DOI: 10.1016/0022-2836(88)90336-1  1
1987 Gasser SM, Laemmli UK. Improved methods for the isolation of individual and clustered mitotic chromosomes. Experimental Cell Research. 173: 85-98. PMID 3678386 DOI: 10.1016/0014-4827(87)90334-X  1
1987 Mirkovitch J, Gasser SM, Laemmli UK. Relation of chromosome structure and gene expression. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 317: 563-74. PMID 2894689 DOI: 10.1098/Rstb.1987.0081  1
1986 Gasser SM, Laemmli UK. The organisation of chromatin loops: characterization of a scaffold attachment site. The Embo Journal. 5: 511-8. PMID 16453673 DOI: 10.1002/J.1460-2075.1986.Tb04240.X  1
1986 Gasser SM, Laroche T, Falquet J, Boy de la Tour E, Laemmli UK. Metaphase chromosome structure. Involvement of topoisomerase II. Journal of Molecular Biology. 188: 613-29. PMID 3016287 DOI: 10.1016/S0022-2836(86)80010-9  1
1986 Gasser SM, Laemmli UK. Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster. Cell. 46: 521-30. PMID 3015418 DOI: 10.1016/0092-8674(86)90877-9  1
1983 Riezman H, Hay R, Gasser S, Daum G, Schneider G, Witte C, Schatz G. The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. The Embo Journal. 2: 1105-11. PMID 16453466 DOI: 10.1002/J.1460-2075.1983.Tb01553.X  1
1983 Gasser SM, Schatz G. Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane. The Journal of Biological Chemistry. 258: 3427-30. PMID 6339485  1
1982 Gasser SM, Ohashi A, Daum G, Böhni PC, Gibson J, Reid GA, Yonetani T, Schatz G. Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps Proceedings of the National Academy of Sciences of the United States of America. 79: 267-271. PMID 7043457 DOI: 10.1073/Pnas.79.2.267  1
1982 Daum G, Gasser SM, Schatz G. Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. The Journal of Biological Chemistry. 257: 13075-80. PMID 6752147  1
1982 Gasser SM, Daum G, Schatz G. Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. The Journal of Biological Chemistry. 257: 13034-41. PMID 6215405  1
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