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Cheng-Wen Wu, MD, PhD - Publications

Affiliations: 
1972-1980 Albert Einstein College of Medicine, New York, New York, United States 
 1980-1990 Stony Brook University, Stony Brook, NY, United States 
 2001- National Yang-Ming University, Allendale Charter Township, Taipei City, Taiwan 
Area:
Molecular Biology
Website:
https://www.thevalleefoundation.org/programs/vvp/cheng-wen-wu-md-phd
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62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lin SC, Chung CH, Chung CH, Kuo MH, Hsieh CH, Chiu YF, Shieh YS, Chou YT, Wu CW. OCT4B mediates hypoxia-induced cancer dissemination. Oncogene. PMID 30209362 DOI: 10.1038/S41388-018-0487-6  0.336
2018 Hong SY, Kao YR, Lee TC, Wu CW. Upregulation of E3 ubiquitin ligase CBLC enhances EGFR dysregulation and signaling in lung adenocarcinoma. Cancer Research. PMID 29945960 DOI: 10.1158/0008-5472.Can-17-3858  0.331
2018 Lee T, Lin Y, Liu Y, Wu C. Abstract 5508: ANKRD52 inhibited tumor metastasis in lung adenocarcinoma Cancer Research. 78: 5508-5508. DOI: 10.1158/1538-7445.Am2018-5508  0.338
2018 Hong S, Kao Y, Lee T, Wu C. Abstract 3319: Epigenetic upregulation of E3 ubiquitin ligase CBLC enhances EGFR dysregulation and signaling Cancer Research. 78: 3319-3319. DOI: 10.1158/1538-7445.Am2018-3319  0.341
2018 Cheng C, Chou K, Wu C, Su N, Peng C, Su Y, Chang J, Ho A, Lin H, Chen CG, Chang Y, Lim K, Chang Y. Abstract 3060: EGFR-mediated interleukin enhancer-binding factor 3 contributes to formation and survival of cancer stem-like tumorspheres through regulating HER3/ERBB3 expression as a therapeutic target against EGFR-positive non-small cell lung cancer Cancer Research. 78: 3060-3060. DOI: 10.1158/1538-7445.Am2018-3060  0.323
2018 Lin Y, Hong S, Kao Y, Wu C. Abstract 2642: CBLC is a potential biomarker for the susceptibility to paclitaxel in lung adenocarcinoma Cancer Research. 78: 2642-2642. DOI: 10.1158/1538-7445.Am2018-2642  0.302
2017 Lin TW, Chen MT, Lin LT, Huang PI, Lo WL, Yang YP, Lu KH, Chen YW, Chiou SH, Wu CW. TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma. Oncotarget. 8: 56612-56625. PMID 28915616 DOI: 10.18632/Oncotarget.17979  0.318
2017 Wen KC, Sung PL, Hsieh SL, Chou YT, Lee OK, Wu CW, Wang PH. α2,3-sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells. Oncotarget. PMID 28423672 DOI: 10.18632/Oncotarget.15994  0.318
2017 Cheng C, Chang J, Lin H, Ho A, Lim K, Chang C, Chang Y, Wu C. Abstract 934: EGFR induces ILF3 and G9a expressions to maintain Oct4-mediated stemness property in lung cancer Cancer Research. 77: 934-934. DOI: 10.1158/1538-7445.Am2017-934  0.307
2017 Lin Y, Liu Y, Lee T, Wu C. Abstract 4843: ANKRD52 inhibited tumor metastasis through dephosphorylation of PAK1 in lung adenocarcinoma Cancer Research. 77: 4843-4843. DOI: 10.1158/1538-7445.Am2017-4843  0.337
2016 Lin SC, Chou YT, Jiang SS, Chang JL, Chung CH, Kao YR, Chang IS, Wu CW. Epigenetic switch between SOX2 and SOX9 regulates cancer cell plasticity. Cancer Research. PMID 27758880 DOI: 10.1158/0008-5472.Can-15-3178  0.33
2016 Pan CM, Wang ML, Chiou SH, Chen HY, Wu CW. Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings. Oncotarget. PMID 27486982 DOI: 10.18632/Oncotarget.10939  0.348
2015 Hong CF, Lin SY, Chou YT, Wu CW. MicroRNA-7 Compromises p53-dependent Apoptosis by Controlling the Expression of the Chromatin Remodeling Factor SMARCD1. The Journal of Biological Chemistry. PMID 26542803 DOI: 10.1074/Jbc.M115.667568  0.305
2015 Kuo HY, Hsu HT, Chen YC, Chang YW, Liu FT, Wu CW. Galectin-3 modulates the EGFR signaling-mediated regulation of Sox2 expression via c-Myc in lung cancer. Glycobiology. PMID 26447186 DOI: 10.1093/Glycob/Cwv088  0.349
2015 Li MY, Lai PL, Chou YT, Chi AP, Mi YZ, Khoo KH, Chang GD, Wu CW, Meng TC, Chen GC. Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation. Oncogene. 34: 3791-803. PMID 25263444 DOI: 10.1038/Onc.2014.312  0.319
2015 Wen K, Wang P, Sung P, Lee M, Wu C. Abstract 5171: EpCAM expression governs tumor growth or distant metastasis of human endometrial cancer: grow or go theory Cancer Research. 75: 5171-5171. DOI: 10.1158/1538-7445.Am2015-5171  0.302
2015 Hsieh C, Chou Y, Wu C. Abstract 40: HB-EGF‑mediated CITED4 signaling in lung cancer Cancer Research. 75: 40-40. DOI: 10.1158/1538-7445.Am2015-40  0.337
2014 Kuo HY, Huang YS, Tseng CH, Chen YC, Chang YW, Shih HM, Wu CW. PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2. Cell Cycle (Georgetown, Tex.). 13: 3132-42. PMID 25486572 DOI: 10.4161/15384101.2014.949212  0.331
2014 Wang Y, Kuo M, Huang C, Hsiao S, Wu C, Chou Y. Abstract 5302: CITED2 as a molecular switch for hypoxia-mediated proliferation Cancer Research. 74: 5302-5302. DOI: 10.1158/1538-7445.Am2014-5302  0.318
2014 Pan C, Wang M, Wu C. Abstract 125: A novel OSM inhibition of cancer metastasis and epithelial‐mesenchymal transition in lung adenocarcinoma through STAT1‐mediated suppression of Slug Cancer Research. 74: 125-125. DOI: 10.1158/1538-7445.Am2014-125  0.358
2013 Kuo HY, Chen YC, Chang HY, Jeng JC, Lin EH, Pan CM, Chang YW, Wang ML, Chou YT, Shih HM, Wu CW. The PML isoform IV is a negative regulator of nuclear EGFR's transcriptional activity in lung cancer. Carcinogenesis. 34: 1708-16. PMID 23563092 DOI: 10.1093/Carcin/Bgt109  0.335
2013 Chou Y, Lee C, Hsiao S, Lin S, Lin S, Wang Y, Wu C. Abstract 5253: SOX2-mediated cell survival and chemoresistance in lung cancer. Cancer Research. 73: 5253-5253. DOI: 10.1158/1538-7445.Am2013-5253  0.322
2013 Kuo H, Chen Y, Chang H, Jeng J, Lin E, Pan C, Wang M, Chou Y, Shih H, Wu C. Abstract 3047: The PML isoform IV is a negative regulator of nuclear EGFR's transcriptional activity in lung cancer. Cancer Research. 73: 3047-3047. DOI: 10.1158/1538-7445.Am2013-3047  0.339
2012 Wang ML, Pan CM, Chiou SH, Chen WH, Chang HY, Lee OK, Hsu HS, Wu CW. Oncostatin m modulates the mesenchymal-epithelial transition of lung adenocarcinoma cells by a mesenchymal stem cell-mediated paracrine effect. Cancer Research. 72: 6051-64. PMID 23139208 DOI: 10.1158/0008-5472.Can-12-1568  0.319
2012 Yeh S, Yang P, Lu H, Chang C, Wu C. Targeting androgen receptor as a new potential therapeutic approach to battle tobacco carcinogens-induced non-small cell lung cancer Journal of Translational Medicine. 10. DOI: 10.1186/1479-5876-10-S2-A8  0.312
2011 Chou Y, Lee C, Lin S, Wu C. Abstract 4992: A Sox2-EGFR positive feedback loop contributes to oncogenesis of lung cancer Cancer Research. 71: 4992-4992. DOI: 10.1158/1538-7445.Am2011-4992  0.326
2011 Lu H, Yeh S, Chou Y, Tsai Y, Chang C, Wu C. Abstract 2126: Androgen receptor regulates lung cancer progress through modulation of OCT-4 expression Cancer Research. 71: 2126-2126. DOI: 10.1158/1538-7445.Am2011-2126  0.321
2010 Chiou SH, Wang ML, Chou YT, Chen CJ, Hong CF, Hsieh WJ, Chang HT, Chen YS, Lin TW, Hsu HS, Wu CW. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Research. 70: 10433-44. PMID 21159654 DOI: 10.1158/0008-5472.Can-10-2638  0.318
2010 Chou Y, Hsu C, Kao Y, Wu C. Abstract 274: Cited2, a novel EGFR-induced coactivator, plays a key role in lung cancer progression Cancer Research. 70: 274-274. DOI: 10.1158/1538-7445.Am10-274  0.344
2009 Hong CF, Chou YT, Lin YS, Wu CW. MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation. The Journal of Biological Chemistry. 284: 19613-22. PMID 19443654 DOI: 10.1074/Jbc.M109.005017  0.343
2005 Shieh YS, Lai CY, Kao YR, Shiah SG, Chu YW, Lee HS, Wu CW. Expression of axl in lung adenocarcinoma and correlation with tumor progression. Neoplasia (New York, N.Y.). 7: 1058-64. PMID 16354588 DOI: 10.1593/Neo.05640  0.301
2005 Chang YW, Chen SC, Cheng EC, Ko YP, Lin YC, Kao YR, Tsay YG, Yang PC, Wu CW, Roffler SR. CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells. International Journal of Cancer. Journal International Du Cancer. 116: 243-52. PMID 15812828 DOI: 10.1002/Ijc.21089  0.306
2004 Hsu CH, Chang MD, Tai KY, Yang YT, Wang PS, Chen CJ, Wang YH, Lee SC, Wu CW, Juan LJ. HCMV IE2-mediated inhibition of HAT activity downregulates p53 function. The Embo Journal. 23: 2269-80. PMID 15141169 DOI: 10.1038/Sj.Emboj.7600239  0.32
2000 Hong T, Yang P, Peck K, Chen JJW, Yang S, Chen Y, Wu C. Profiling the downstream genes of tumor suppressor PTEN in lung cancer cells by complementary DNA microarray American Journal of Respiratory Cell and Molecular Biology. 23: 355-363. PMID 10970827 DOI: 10.1165/Ajrcmb.23.3.4002  0.33
2000 Huang CF, Wang YC, Tsao DA, Tung SF, Lin YS, Wu CW. Antagonism between members of the CNC-bZIP family and the immediate-early protein IE2 of human cytomegalovirus. The Journal of Biological Chemistry. 275: 12313-20. PMID 10766871 DOI: 10.1074/Jbc.275.16.12313  0.314
1999 Tung SF, Chuang JY, Lin CT, Lai MY, Wu CW, Lin YS. Inhibition of hTAFII32-binding implicated in the transcriptional repression by central regions of mutant p53 proteins. The Journal of Biological Chemistry. 274: 7748-55. PMID 10075665 DOI: 10.1074/Jbc.274.12.7748  0.303
1998 Tsao DA, Wu CW, Lin YS. Molecular cloning of bovine telomerase RNA. Gene. 221: 51-8. PMID 9852949 DOI: 10.1016/S0378-1119(98)00432-6  0.332
1998 Tsai HL, Kou GH, Tang FM, Wu CW, Lin YS. Negative regulation of a heterologous promoter by human cytomegalovirus immediate-early protein IE2. Virology. 238: 372-9. PMID 9400610 DOI: 10.1006/Viro.1997.8855  0.303
1978 Wu CW. Photochemical cross-linking studies on the interaction of escherichia coli RNA polymerase with T7 DNA Biochemistry. 17: 2954-2961. PMID 359036 DOI: 10.1021/Bi00608A003  0.341
1978 Wu FYH, Wu CW. Inhibition of Escherichia coli RNA polymerase by bis(1-anilino-8-naphthalenesulfonate) Biochemistry. 17: 138-144. PMID 338032 DOI: 10.1021/Bi00594A020  0.381
1978 Speckhard DC, Wu FY, Wu CW. Role of the intrinsic metal in RNA polymerase from Escherichia coli. In vivo substitution of tightly bound zinc with cobalt. Biochemistry. 16: 5228-34. PMID 336082 DOI: 10.1021/Bi00643A011  0.305
1977 Wu C, Yarbrough L, Wu F, Hillel Z. Corrections - Spatial relationship of the δ Subunit and the Rifampicin Binding Site in RNA Polymerase of Escherichia coli Biochemistry. 16: 2312-2312. DOI: 10.1021/Bi00629A600  0.667
1976 Wu FY, Yarbrough LR, Wu CW. Conformational transition of Escherichia coli RNA polymerase induced by the interaction of sigma subunit with core enzyme. Biochemistry. 15: 3254-8. PMID 782516 DOI: 10.1021/Bi00660A014  0.692
1976 Yarbrough LR, Wu FY, Wu CW. Molecular mechanism of the rifampicin -RNA polymerase interaction. Biochemistry. 15: 2669-76. PMID 779828 DOI: 10.1021/bi00657a029  0.67
1976 Wu CW, Yarbrough LR, Wu FY, Hillel Z. Spatial relationship of the sigma subunit and the rifampicin binding site in RNA polymerase of Escherichia coli. Biochemistry. 15: 2097-104. PMID 776217 DOI: 10.1021/Bi00655A011  0.684
1976 Wu CW, Yarbrough LR. N-(1-pyrene)maleimide: a fluorescent cross-linking reagent. Biochemistry. 15: 2863-8. PMID 7290 DOI: 10.1021/bi00658a025  0.611
1975 Wu CW, Yarbrough LR, Hillel Z, Wu FY. Sigma cycle during in vitro transcription: demonstration by nanosecond fluorescence depolarization spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 72: 3019-23. PMID 1103133 DOI: 10.1073/Pnas.72.8.3019  0.676
1974 Yarbrough LR, Wu CW. Role of sulfhydryl residues of Escherichia coli ribonucleic acid polymerase in template recognition and specific initiation Journal of Biological Chemistry. 249: 4079-4085. PMID 4605073  0.666
1974 Hammes GG, Wu CW. Kinetics of allosteric enzymes Annual Review of Biophysics and Bioengineering. 3: 1-33. PMID 4371650  0.458
1974 Wu FYH, Wu CW. Fluorescent affinity labeling of initiation site on ribonucleic acid polymerase of Escherichia coli Biochemistry. 13: 2562-2566. PMID 4364835 DOI: 10.1021/Bi00709A014  0.412
1973 Steinemann A, Wu C, Stryer L. Conformational aspects of rhodopsin and retinal disc membranes. Journal of Supramolecular Structure. 1: 348-53. PMID 4767463 DOI: 10.1002/jss.400010410  0.473
1973 Wu CW, Hammes GG. Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with an adenosine 5′-triphosphate analog Biochemistry. 12: 1400-1408. PMID 4572360 DOI: 10.1021/Bi00731A021  0.513
1972 Wu CW, Stryer L. Proximity relationships in rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 69: 1104-8. PMID 4504322 DOI: 10.1073/Pnas.69.5.1104  0.503
1971 Scrutton MC, Wu CW, Goldthwait DA. The presence and possible role of zinc in RNA polymerase obtained from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 68: 2497-501. PMID 4944629 DOI: 10.1073/Pnas.68.10.2497  0.619
1971 Hammes GG, Wu CW. Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with carbamyl phosphate Biochemistry. 10: 2150-2156. PMID 4935107 DOI: 10.1021/Bi00787A030  0.484
1971 Hammes GG, Wu CW. Regulation of enzyme activity Science. 172: 1205-1211. PMID 4930512 DOI: 10.1126/Science.172.3989.1205  0.459
1971 Hammes GG, Wu CW. Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with aspartate analogs Biochemistry. 10: 1051-1057. PMID 4927804 DOI: 10.1021/Bi00782A018  0.483
1970 Hammes GG, Porter RW, Wu CW. Determination of the number of regulatory and catalytic sites on aspartate transcarbamylase. Biochemistry. 9: 2992-4. PMID 5474800 DOI: 10.1021/Bi00817A009  0.428
1970 Eckfeldt J, Hammes GG, Mohr SC, Wu CW. Relaxation spectra of aspartate transcarbamylase. I. Interaction of 5-bromocytidine triphosphate with native enzyme and regulatory subunit Biochemistry. 9: 3353-3362. PMID 4941833 DOI: 10.1021/Bi00819A010  0.495
1969 Wu CW, Goldthwait DA. Studies of nucleotide binding to the ribonucleic acid polymerase by equilibrium dialysis. Biochemistry. 8: 4458-64. PMID 4900995 DOI: 10.1021/Bi00839A035  0.585
1969 Wu CW, Goldthwait DA. Studies of nucleotide binding to the ribonucleic acid polymerase by a fluoresence technique. Biochemistry. 8: 4450-8. PMID 4900994 DOI: 10.1021/Bi00839A034  0.579
1969 Anthony DD, Goldthwait DA, Wu CW. Studies with the ribonucleic acid polymerase. II. Kinetic aspects of initiation and polymerization. Biochemistry. 8: 246-56. PMID 4887854 DOI: 10.1021/Bi00829A035  0.562
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